Q9Y233

cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A // UniProt Profile

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Species	H. sapiens
Number of Interactions	8 / 8
Average Interaction Score	0.544

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Perikaryon (GO:0043204)	0.987	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.987	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.987	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.987	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.987	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: inferred from electronic annotation	GO	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

Q9Y233

Interaction Score

0.995

P14866

(UniProtKB/Swiss-Prot/P) Details

Heterogeneous nuclear ribonucleoprotein L

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Ribonucleoprotein complex (GO:0030529)	0.999	Experimental: experimental	Organelle	PubMed
Cytosol	Ribonucleoprotein granule (GO:0035770)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.999	Experimental: experimental	Human Proteinpedia	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.999	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y233

Interaction Score

0.986

P42574

(UniProtKB/Swiss-Prot/P) Details

Caspase-3

Q9Y233

Interaction Score

0.959

P11387

(UniProtKB/Swiss-Prot/P) Details

DNA topoisomerase 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Perikaryon (GO:0043204)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasmic mRNA processing body (GO:0000932)	0.972	Experimental: inferred from direct assay	GO	PubMed
Cytosol	DNA topoisomerase complex (ATP-hydrolyzing) (GO:0009330)	0.972	Experimental: inferred from mutant phenotype	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Nucleus	Fibrillar center (GO:0001650)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Fibrillar center (GO:0001650)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Nucleus	Protein-DNA complex (GO:0032993)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Nucleus	Nuclear chromosome (GO:0000228)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Replication fork protection complex (GO:0031298)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y233

Interaction Score

0.72

P47710

(UniProtKB/Swiss-Prot/P) Details

Alpha-S1-casein

Q9Y233

Interaction Score

0.691

Q9UNX4

(UniProtKB/Swiss-Prot/P) Details

WD repeat-containing protein 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Small-subunit processome (GO:0032040)	0.7	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Pwp2p-containing subcomplex of 90S preribosome (GO:0034388)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nuclear membrane (GO:0031965)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear membrane (GO:0031965)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q9Y233

Interaction Score

Q5TDG3

(UniProtKB/TrEmbl/P) Details

WD repeat domain 3, isoform CRA_b

Q9Y233

Interaction Score

Q9BVT2

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein

Q9Y233

Interaction Score

Q6NTA2

(UniProtKB/TrEmbl/P) Details

HNRNPL protein

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Q9Y233

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

Q9Y233

P14866

Heterogeneous nuclear ribonucleoprotein L

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9Y233

P42574

Caspase-3

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9Y233

P11387

DNA topoisomerase 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9Y233

P47710

Alpha-S1-casein

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9Y233

Q9UNX4

WD repeat-containing protein 3

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9Y233

Q5TDG3

WD repeat domain 3, isoform CRA_b

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9Y233

Q9BVT2

Uncharacterized protein

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9Y233

Q6NTA2

HNRNPL protein

Localizations:

Interaction Source Database:

Interaction Source Publication: