Q9Y4B6

DDB1- and CUL4-associated factor 1 // UniProt Profile

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Species	H. sapiens
Number of Interactions	166 / 229
Average Interaction Score	0.907

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	CUL4 RING ubiquitin ligase complex (GO:0080008)	0.86	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Fibrillar center (GO:0001650)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Fibrillar center (GO:0001650)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Signalosome (GO:0008180)	1	Experimental: inferred from direct assay	GO	PubMed

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Interactions

All Details

Q9Y4B6

Interaction Score

O14746

(UniProtKB/Swiss-Prot/P) Details

Telomerase reverse transcriptase

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Ribonucleoprotein complex (GO:0030529)	0.999	Experimental: experimental	Organelle	PubMed
Cytosol	Telomerase holoenzyme complex (GO:0005697)	0.999	Unknown: traceable author statement	GO	PubMed
Cytosol	Telomerase catalytic core complex (GO:0000333)	0.999	Experimental: inferred from mutant phenotype	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial nucleoid (GO:0042645)	0.8	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	PML body (GO:0016605)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear telomere cap complex (GO:0000783)	1	Unknown: inferred by curator	GO	PubMed
Nucleus	RNA-directed RNA polymerase complex (GO:0031379)	1	Predicted: inferred from physical interaction	GO	PubMed
Nucleus	Chromosome (GO:0005694)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nuclear chromosome, telomeric region (GO:0000784)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Chromosome, telomeric region (GO:0000781)	1	Unknown: inferred by curator	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.79	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.79	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y4B6

Interaction Score

P04637

(UniProtKB/Swiss-Prot/P) Details

Cellular tumor antigen p53

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular (GO:0005622)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.972	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.972	Experimental: experimental	Organelle	PubMed
Mitochondrion	Mitochondrial matrix (GO:0005759)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear matrix (GO:0016363)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	PML body (GO:0016605)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Transcription factor TFIID complex (GO:0005669)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nuclear chromatin (GO:0000790)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Replication fork (GO:0005657)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y4B6

Interaction Score

Q8IY92

(UniProtKB/Swiss-Prot/P) Details

Structure-specific endonuclease subunit SLX4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Holliday junction resolvase complex (GO:0048476)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear chromosome, telomeric region (GO:0000784)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Slx1-Slx4 complex (GO:0033557)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear chromatin (GO:0000790)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	ERCC4-ERCC1 complex (GO:0070522)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Chromosome, telomeric region (GO:0000781)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q9Y4B6

Interaction Score

P03372

(UniProtKB/Swiss-Prot/P) Details

Estrogen receptor

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
N/A	Transcriptional preinitiation complex (GO:0097550)	0.8	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.992	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.992	Unknown: traceable author statement	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Chromosome (GO:0005694)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nuclear chromatin (GO:0000790)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Transcriptionally active chromatin (GO:0035327)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.902	Unknown: non-traceable author statement	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.902	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y4B6

Interaction Score

P07992

(UniProtKB/Swiss-Prot/P) Details

DNA excision repair protein ERCC-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	0.94	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Transcription factor TFIID complex (GO:0005669)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nuclear chromosome, telomeric region (GO:0000784)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleotide-excision repair complex (GO:0000109)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	ERCC4-ERCC1 complex (GO:0070522)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleotide-excision repair factor 1 complex (GO:0000110)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q9Y4B6

Interaction Score

P19338

(UniProtKB/Swiss-Prot/P) Details

Nucleolin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.958	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cell cortex (GO:0005938)	0.958	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.958	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y4B6

Interaction Score

Q92547

(UniProtKB/Swiss-Prot/P) Details

DNA topoisomerase 2-binding protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.931	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Male germ cell nucleus (GO:0001673)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	PML body (GO:0016605)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Spindle pole (GO:0000922)	0.931	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	0.931	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	0.931	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Chromosome (GO:0005694)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Condensed nuclear chromosome (GO:0000794)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y4B6

Interaction Score

Q13547

(UniProtKB/Swiss-Prot/P) Details

Histone deacetylase 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Neuronal cell body (GO:0043025)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.902	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.902	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	NuRD complex (GO:0016581)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Transcription factor complex (GO:0005667)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Unknown: HDA	GO	PubMed
Nucleus	Histone deacetylase complex (GO:0000118)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Sin3 complex (GO:0016580)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear chromatin (GO:0000790)	1	Unknown: HDA	GO	PubMed
Nucleus	Chromatin (GO:0000785)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Heterochromatin (GO:0000792)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y4B6

Interaction Score

O15379

(UniProtKB/Swiss-Prot/P) Details

Histone deacetylase 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.972	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.972	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Transcriptional repressor complex (GO:0017053)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Histone deacetylase complex (GO:0000118)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.96	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Spindle microtubule (GO:0005876)	0.972	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.8	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y4B6

Interaction Score

P78527

(UniProtKB/Swiss-Prot/P) Details

DNA-dependent protein kinase catalytic subunit

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.86	Unknown: traceable author statement	GO	PubMed
Cytosol	Nonhomologous end joining complex (GO:0070419)	0.86	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Transcription factor complex (GO:0005667)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Nucleus	Protein-DNA complex (GO:0032993)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	DNA-dependent protein kinase-DNA ligase 4 complex (GO:0005958)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear chromosome, telomeric region (GO:0000784)	1	Unknown: HDA	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.96	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.96	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y4B6

Interaction Score

O95071

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase UBR5

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.992	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y4B6

Interaction Score

Q01081

(UniProtKB/Swiss-Prot/P) Details

Splicing factor U2AF 35 kDa subunit

Q9Y4B6

Interaction Score

Q9BY41

(UniProtKB/Swiss-Prot/P) Details

Histone deacetylase 8

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.79	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.79	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Histone deacetylase complex (GO:0000118)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Chromosome (GO:0005694)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nuclear chromosome (GO:0000228)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y4B6

Interaction Score

Q99627

(UniProtKB/Swiss-Prot/P) Details

COP9 signalosome complex subunit 8

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Signalosome (GO:0008180)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y4B6

Interaction Score

Q96S94

(UniProtKB/Swiss-Prot/P) Details

Cyclin-L2

Q9Y4B6

Interaction Score

Q92769

(UniProtKB/Swiss-Prot/P) Details

Histone deacetylase 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.3	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	NuRD complex (GO:0016581)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Unknown: HDA	GO	PubMed
Nucleus	ESC/E(Z) complex (GO:0035098)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Sin3 complex (GO:0016580)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear chromatin (GO:0000790)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y4B6

Interaction Score

Q7L590

(UniProtKB/Swiss-Prot/P) Details

Protein MCM10 homolog

Q9Y4B6

Interaction Score

Q92889

(UniProtKB/Swiss-Prot/P) Details

DNA repair endonuclease XPF

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Transcription factor TFIID complex (GO:0005669)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nuclear chromosome, telomeric region (GO:0000784)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleotide-excision repair complex (GO:0000109)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	ERCC4-ERCC1 complex (GO:0070522)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleotide-excision repair factor 1 complex (GO:0000110)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Chromosome, telomeric region (GO:0000781)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q9Y4B6

Interaction Score

P16403

(UniProtKB/Swiss-Prot/P) Details

Histone H1.2

Q9Y4B6

Interaction Score

P22736

(UniProtKB/Swiss-Prot/P) Details

Nuclear receptor subfamily 4 group A member 1

Q9Y4B6

Interaction Score

Q14527

(UniProtKB/Swiss-Prot/P) Details

Helicase-like transcription factor

Q9Y4B6

Interaction Score

Q9BT78

(UniProtKB/Swiss-Prot/P) Details

COP9 signalosome complex subunit 4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.996	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.996	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.996	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.996	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Unknown: HDA	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Signalosome (GO:0008180)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Synaptic vesicle (GO:0008021)	0.8	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.8	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y4B6

Interaction Score

Q96T60

(UniProtKB/Swiss-Prot/P) Details

Bifunctional polynucleotide phosphatase/kinase

Q9Y4B6

Interaction Score

Q9NWT8

(UniProtKB/Swiss-Prot/P) Details

Aurora kinase A-interacting protein

Q9Y4B6

Interaction Score

P48431

(UniProtKB/Swiss-Prot/P) Details

Transcription factor SOX-2

Q9Y4B6

Interaction Score

Q92905

(UniProtKB/Swiss-Prot/P) Details

COP9 signalosome complex subunit 5

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Eukaryotic translation initiation factor 3 complex (GO:0005852)	0.999	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Signalosome (GO:0008180)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Synaptic vesicle (GO:0008021)	0.8	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Chromatin (GO:0000785)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.3	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

Q9Y4B6

Interaction Score

Q16531

(UniProtKB/Swiss-Prot/P) Details

DNA damage-binding protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	CUL4 RING ubiquitin ligase complex (GO:0080008)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Cytosol	Cul4A-RING ubiquitin ligase complex (GO:0031464)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cul4B-RING ubiquitin ligase complex (GO:0031465)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Nucleus	Nuclear chromosome, telomeric region (GO:0000784)	1	Unknown: HDA	GO	PubMed
Extracellular	Extracellular space (GO:0005615)	0.3	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	0.8	Experimental: experimental	MatrixDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

Q9Y4B6

Interaction Score

Q9Y3Z3

(UniProtKB/Swiss-Prot/P) Details

Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

Q9Y4B6

Interaction Score

P35240

(UniProtKB/Swiss-Prot/P) Details

Merlin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cleavage furrow (GO:0032154)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cell body (GO:0044297)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Apical part of cell (GO:0045177)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Early endosome (GO:0005769)	0.8	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Cortical actin cytoskeleton (GO:0030864)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Ruffle membrane (GO:0032587)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Lamellipodium (GO:0030027)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Filopodium membrane (GO:0031527)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Neuron projection (GO:0043005)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Membrane (GO:0016020)	1	Unknown: HDA	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Human Proteinpedia	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Vesicle (GO:0031982)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Adherens junction (GO:0005912)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

HPRD, BioGRID

Interaction Source Publication:

PubMed

Q9Y4B6

Interaction Score

Q9UBW8

(UniProtKB/Swiss-Prot/P) Details

COP9 signalosome complex subunit 7a

Q9Y4B6

Interaction Score

Q9UNS2

(UniProtKB/Swiss-Prot/P) Details

COP9 signalosome complex subunit 3

Q9Y4B6

Interaction Score

Q96NY9

(UniProtKB/Swiss-Prot/P) Details

Crossover junction endonuclease MUS81

Q9Y4B6

Interaction Score

P39687

(UniProtKB/Swiss-Prot/P) Details

Acidic leucine-rich nuclear phosphoprotein 32 family member A

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.999	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.96	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.96	Experimental: experimental	Organelle	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y4B6

Interaction Score

Q16539

(UniProtKB/Swiss-Prot/P) Details

Mitogen-activated protein kinase 14

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.997	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.997	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.997	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.997	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.997	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.79	Predicted: SVM decision tree	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.79	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.999	Unknown: traceable author statement	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Secretory granule lumen (GO:0034774)	0.3	Unknown: traceable author statement	GO	PubMed
Cytosol	Spindle pole (GO:0000922)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.3	Unknown: traceable author statement	GO	PubMed
Membrane	Membrane (GO:0016020)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y4B6

Interaction Score

Q96AY2

(UniProtKB/Swiss-Prot/P) Details

Crossover junction endonuclease EME1

Q9Y4B6

Interaction Score

Q8IY81

(UniProtKB/Swiss-Prot/P) Details

pre-rRNA processing protein FTSJ3

Q9Y4B6

Interaction Score

Q7L5N1

(UniProtKB/Swiss-Prot/P) Details

COP9 signalosome complex subunit 6

Q9Y4B6

Interaction Score

Q9NRC8

(UniProtKB/Swiss-Prot/P) Details

NAD-dependent protein deacetylase sirtuin-7

Q9Y4B6

Interaction Score

Q9H9Q2

(UniProtKB/Swiss-Prot/P) Details

COP9 signalosome complex subunit 7b

Q9Y4B6

Interaction Score

Q13315

(UniProtKB/Swiss-Prot/P) Details

Serine-protein kinase ATM

Q9Y4B6

Interaction Score

O60293

(UniProtKB/Swiss-Prot/P) Details

Zinc finger C3H1 domain-containing protein

Q9Y4B6

Interaction Score

Q01860

(UniProtKB/Swiss-Prot/P) Details

POU domain, class 5, transcription factor 1

Q9Y4B6

Interaction Score

O43151

(UniProtKB/Swiss-Prot/P) Details

Methylcytosine dioxygenase TET3

Q9Y4B6

Interaction Score

P68431

(UniProtKB/Swiss-Prot/P) Details

Histone H3.1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear chromosome (GO:0000228)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleosome (GO:0000786)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nuclear nucleosome (GO:0000788)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.86	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	0.86	Experimental: experimental	MatrixDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.3	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y4B6

Interaction Score

Q16695

(UniProtKB/Swiss-Prot/P) Details

Histone H3.1t

Q9Y4B6

Interaction Score

Q9NRM7

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein kinase LATS2

Q9Y4B6

Interaction Score

Q15843

(UniProtKB/Swiss-Prot/P) Details

NEDD8

Q9Y4B6

Interaction Score

Q13535

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein kinase ATR

Q9Y4B6

Interaction Score

Q9UM54

(UniProtKB/Swiss-Prot/P) Details

Unconventional myosin-VI

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Coated pit (GO:0005905)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Apical part of cell (GO:0045177)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cell cortex (GO:0005938)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear membrane (GO:0031965)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	DNA-directed RNA polymerase II, holoenzyme (GO:0016591)	0.998	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Lysosomal membrane (GO:0005765)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.998	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endocytic vesicle (GO:0030139)	0.998	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Clathrin coated vesicle membrane (GO:0030665)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Clathrin-coated endocytic vesicle (GO:0045334)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Unconventional myosin complex (GO:0016461)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Filamentous actin (GO:0031941)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Ruffle (GO:0001726)	0.952	Experimental: inferred from direct assay	GO	PubMed
Membrane	Ruffle membrane (GO:0032587)	0.952	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Microvillus (GO:0005902)	0.952	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.952	Unknown: HDA	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.952	Unknown: traceable author statement	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y4B6

Interaction Score

Q9BV73

(UniProtKB/Swiss-Prot/P) Details

Centrosome-associated protein CEP250

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: experimental	Organelle	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.998	Experimental: inferred from mutant phenotype	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	1	Unknown: non-traceable author statement	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Centriole (GO:0005814)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Chromosome (GO:0005694)	0.998	Experimental: experimental	Organelle	PubMed
Membrane	Cilium (GO:0005929)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y4B6

Interaction Score

Q08050

(UniProtKB/Swiss-Prot/P) Details

Forkhead box protein M1

Q9Y4B6

Interaction Score

Q5SY16

(UniProtKB/Swiss-Prot/P) Details

Polynucleotide 5'-hydroxyl-kinase NOL9

Q9Y4B6

Interaction Score

P62877

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase RBX1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	VCB complex (GO:0030891)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cullin-RING ubiquitin ligase complex (GO:0031461)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cul7-RING ubiquitin ligase complex (GO:0031467)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cul3-RING ubiquitin ligase complex (GO:0031463)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cul2-RING ubiquitin ligase complex (GO:0031462)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cul5-RING ubiquitin ligase complex (GO:0031466)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cul4A-RING ubiquitin ligase complex (GO:0031464)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cul4B-RING ubiquitin ligase complex (GO:0031465)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	SCF ubiquitin ligase complex (GO:0019005)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Nuclear SCF ubiquitin ligase complex (GO:0043224)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y4B6

Interaction Score

0.999

Q13620

(UniProtKB/Swiss-Prot/P) Details

Cullin-4B

Q9Y4B6

Interaction Score

0.999

P55895

(UniProtKB/Swiss-Prot/P) Details

V(D)J recombination-activating protein 2

Q9Y4B6

Interaction Score

0.999

Q8NFU7

(UniProtKB/Swiss-Prot/P) Details

Methylcytosine dioxygenase TET1

Q9Y4B6

Interaction Score

0.999

O43303

(UniProtKB/Swiss-Prot/P) Details

Centriolar coiled-coil protein of 110 kDa

Q9Y4B6

Interaction Score

0.999

O14978

(UniProtKB/Swiss-Prot/P) Details

Zinc finger protein 263

Q9Y4B6

Interaction Score

0.999

O15213

(UniProtKB/Swiss-Prot/P) Details

WD repeat-containing protein 46

Q9Y4B6

Interaction Score

0.999

Q92630

(UniProtKB/Swiss-Prot/P) Details

Dual specificity tyrosine-phosphorylation-regulated kinase 2

Q9Y4B6

Interaction Score

0.999

Q07020

(UniProtKB/Swiss-Prot/P) Details

60S ribosomal protein L18

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Ribonucleoprotein complex (GO:0030529)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Polysomal ribosome (GO:0042788)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytosolic large ribosomal subunit (GO:0022625)	1	Unknown: HDA	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Unknown: HDA	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	0.992	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.972	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.972	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Rough endoplasmic reticulum (GO:0005791)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.51	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.51	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y4B6

Interaction Score

0.998

P35398

(UniProtKB/Swiss-Prot/P) Details

Nuclear receptor ROR-alpha

Q9Y4B6

Interaction Score

0.998

Q02539

(UniProtKB/Swiss-Prot/P) Details

Histone H1.1

Q9Y4B6

Interaction Score

0.998

Q6N021

(UniProtKB/Swiss-Prot/P) Details

Methylcytosine dioxygenase TET2

Q9Y4B6

Interaction Score

0.998

P49116

(UniProtKB/Swiss-Prot/P) Details

Nuclear receptor subfamily 2 group C member 2

Q9Y4B6

Interaction Score

0.997

Q9H0W8

(UniProtKB/Swiss-Prot/P) Details

Protein SMG9

Q9Y4B6

Interaction Score

0.997

O94888

(UniProtKB/Swiss-Prot/P) Details

UBX domain-containing protein 7

Q9Y4B6

Interaction Score

0.997

Q9BW61

(UniProtKB/Swiss-Prot/P) Details

DET1- and DDB1-associated protein 1

Q9Y4B6

Interaction Score

0.997

Q9BRQ0

(UniProtKB/Swiss-Prot/P) Details

Pygopus homolog 2

Q9Y4B6

Interaction Score

0.996

P15918

(UniProtKB/Swiss-Prot/P) Details

V(D)J recombination-activating protein 1

Q9Y4B6

Interaction Score

0.996

Q6K0P9

(UniProtKB/Swiss-Prot/P) Details

Pyrin and HIN domain-containing protein 1

Q9Y4B6

Interaction Score

0.996

P30153

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Protein phosphatase type 2A complex (GO:0000159)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.86	Unknown: non-traceable author statement	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.86	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	0.972	Unknown: non-traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.972	Experimental: experimental	Organelle	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Unknown: non-traceable author statement	GO	PubMed
Nucleus	Chromosome, centromeric region (GO:0000775)	0.972	Experimental: inferred from direct assay	GO	PubMed
Membrane	Dendrite (GO:0030425)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.657	Unknown: non-traceable author statement	GO	PubMed
Membrane	Lateral plasma membrane (GO:0016328)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y4B6

Interaction Score

0.996

Q96MN5

(UniProtKB/Swiss-Prot/P) Details

Transcription elongation factor A N-terminal and central domain-containing protein 2

Q9Y4B6

Interaction Score

0.996

Q13616

(UniProtKB/Swiss-Prot/P) Details

Cullin-1

Q9Y4B6

Interaction Score

0.996

P26373

(UniProtKB/Swiss-Prot/P) Details

60S ribosomal protein L13

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	Organelle	PubMed
Cytosol	Ribonucleoprotein complex (GO:0030529)	0.999	Experimental: experimental	Organelle	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytosolic ribosome (GO:0022626)	0.999	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosolic large ribosomal subunit (GO:0022625)	0.999	Unknown: HDA	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.972	Unknown: HDA	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	0.972	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	0.972	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.96	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y4B6

Interaction Score

0.996

P18124

(UniProtKB/Swiss-Prot/P) Details

60S ribosomal protein L7

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Unknown: HDA	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	Organelle	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Ribonucleoprotein complex (GO:0030529)	0.999	Experimental: experimental	Organelle	PubMed
Cytosol	Polysome (GO:0005844)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytosolic large ribosomal subunit (GO:0022625)	0.999	Unknown: HDA	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.971	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.971	Unknown: HDA	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	0.971	Unknown: HDA	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	0.971	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Postsynaptic density (GO:0014069)	0.902	Experimental: inferred from experiment	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.902	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.902	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y4B6

Interaction Score

0.996

Q8NHY2

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase COP1

Q9Y4B6

Interaction Score

0.994

P30154

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.8	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Membrane raft (GO:0045121)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y4B6

Interaction Score

0.994

Q96GG9

(UniProtKB/Swiss-Prot/P) Details

DCN1-like protein 1

Q9Y4B6

Interaction Score

0.994

Q8IVT5

(UniProtKB/Swiss-Prot/P) Details

Kinase suppressor of Ras 1

Q9Y4B6

Interaction Score

0.994

Q8IWL3

(UniProtKB/Swiss-Prot/P) Details

Iron-sulfur cluster co-chaperone protein HscB, mitochondrial

Q9Y4B6

Interaction Score

0.994

Q13619

(UniProtKB/Swiss-Prot/P) Details

Cullin-4A

Q9Y4B6

Interaction Score

0.994

P13051

(UniProtKB/Swiss-Prot/P) Details

Uracil-DNA glycosylase

Q9Y4B6

Interaction Score

0.994

Q9Y6A4

(UniProtKB/Swiss-Prot/P) Details

Cilia- and flagella-associated protein 20

Q9Y4B6

Interaction Score

0.993

P62241

(UniProtKB/Swiss-Prot/P) Details

40S ribosomal protein S8

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.98	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.98	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytosolic small ribosomal subunit (GO:0022627)	0.98	Unknown: HDA	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.956	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.956	Unknown: HDA	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.956	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.956	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.96	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.51	Unknown: HDA	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.98	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.51	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y4B6

Interaction Score

0.993

P0CG48

(UniProtKB/Swiss-Prot/P) Details

Polyubiquitin-C

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Myelin sheath (GO:0043209)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.969	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.969	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytosol (GO:0005829)	0.969	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrial outer membrane (GO:0005741)	0.3	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.956	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.956	Unknown: HDA	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.956	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.956	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.657	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endosome membrane (GO:0010008)	0.657	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endocytic vesicle membrane (GO:0030666)	0.657	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.902	Experimental: experimental	MatrixDB	PubMed
Extracellular	Host cell (GO:0043657)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular space (GO:0005615)	0.902	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	0.902	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.902	Unknown: traceable author statement	GO	PubMed
Cytosol	Vesicle (GO:0031982)	0.969	Unknown: HDA	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.969	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y4B6

Interaction Score

0.992

O75449

(UniProtKB/Swiss-Prot/P) Details

Katanin p60 ATPase-containing subunit A1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Midbody (GO:0030496)	0.8	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Spindle (GO:0005819)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Spindle pole (GO:0000922)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Mitotic spindle pole (GO:0097431)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Centrosome (GO:0005813)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Microtubule (GO:0005874)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y4B6

Interaction Score

0.992

Q9H492

(UniProtKB/Swiss-Prot/P) Details

Microtubule-associated proteins 1A/1B light chain 3A

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Experimental: experimental	Human Proteinpedia	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.79	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Late endosome (GO:0005770)	0.79	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Autophagic vacuole (GO:0005776)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Autophagic vacuole membrane (GO:0000421)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Microtubule (GO:0005874)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.86	Experimental: experimental	eSLDB	PubMed
Cytosol	Organelle membrane (GO:0031090)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Synapse (GO:0045202)	0.86	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y4B6

Interaction Score

0.991

O95835

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein kinase LATS1

Q9Y4B6

Interaction Score

0.99

J3KNF3

(UniProtKB/TrEmbl/P) Details

Methylcytosine dioxygenase TET3

Q9Y4B6

Interaction Score

0.988

Q9Y5L4

(UniProtKB/Swiss-Prot/P) Details

Mitochondrial import inner membrane translocase subunit Tim13

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: pTarget method	LOCATE	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	Organelle	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial intermembrane space protein transporter complex (GO:0042719)	1	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrial inner membrane (GO:0005743)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Fibrillar center (GO:0001650)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Fibrillar center (GO:0001650)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.8	Experimental: experimental	eSLDB	PubMed
Cytosol	Organelle inner membrane (GO:0019866)	0.8	Experimental: experimental	Organelle	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y4B6

Interaction Score

0.988

A0A0D9SFF0

(UniProtKB/TrEmbl/P) Details

Forkhead box protein M1

Q9Y4B6

Interaction Score

0.987

Q96C28

(UniProtKB/Swiss-Prot/P) Details

Zinc finger protein 707

Q9Y4B6

Interaction Score

0.981

Q53GA5

(UniProtKB/TrEmbl/P) Details

Cellular tumor antigen p53

Q9Y4B6

Interaction Score

0.98

P62837

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin-conjugating enzyme E2 D2

Q9Y4B6

Interaction Score

0.976

Q9UBT1

(UniProtKB/TrEmbl/P) Details

Estrogen receptor

Q9Y4B6

Interaction Score

0.972

Q6P1M3

(UniProtKB/Swiss-Prot/P) Details

Lethal(2) giant larvae protein homolog 2

Q9Y4B6

Interaction Score

0.971

Q96BY2

(UniProtKB/Swiss-Prot/P) Details

Modulator of apoptosis 1

Q9Y4B6

Interaction Score

0.97

Q02878

(UniProtKB/Swiss-Prot/P) Details

60S ribosomal protein L6

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	Organelle	PubMed
Cytosol	Ribonucleoprotein complex (GO:0030529)	0.999	Experimental: experimental	Organelle	PubMed
Cytosol	Polysomal ribosome (GO:0042788)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosolic large ribosomal subunit (GO:0022625)	0.999	Unknown: HDA	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.79	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.79	Unknown: HDA	GO	PubMed
Secretory-pathway	Rough endoplasmic reticulum (GO:0005791)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Postsynaptic density (GO:0014069)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.96	Experimental: experimental	MatrixDB	PubMed
Extracellular	Intercellular bridge (GO:0045171)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Membrane (GO:0016020)	0.657	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.657	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y4B6

Interaction Score

0.958

Q96EV8

(UniProtKB/Swiss-Prot/P) Details

Dysbindin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Midbody (GO:0030496)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Midbody (GO:0030496)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Sarcoplasm (GO:0016528)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	BLOC-1 complex (GO:0031083)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.956	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Endosome membrane (GO:0010008)	0.956	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Melanosome membrane (GO:0033162)	0.956	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Synaptic vesicle membrane (GO:0030672)	0.956	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Growth cone (GO:0030426)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Neuron projection (GO:0043005)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Dendritic spine (GO:0043197)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Postsynaptic density (GO:0014069)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Axon (GO:0030424)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Sarcolemma (GO:0042383)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Postsynaptic membrane (GO:0045211)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y4B6

Interaction Score

0.958

P13533

(UniProtKB/Swiss-Prot/P) Details

Myosin-6

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Myofibril (GO:0030016)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Sarcomere (GO:0030017)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Z disc (GO:0030018)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Myosin complex (GO:0016459)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Myosin filament (GO:0032982)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Muscle myosin complex (GO:0005859)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Stress fiber (GO:0001725)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y4B6

Interaction Score

0.958

Q5JTW2

(UniProtKB/Swiss-Prot/P) Details

Centrosomal protein of 78 kDa

Q9Y4B6

Interaction Score

0.957

Q93034

(UniProtKB/Swiss-Prot/P) Details

Cullin-5

Q9Y4B6

Interaction Score

0.953

Q9Y2B4

(UniProtKB/Swiss-Prot/P) Details

TP53-target gene 5 protein

Q9Y4B6

Interaction Score

0.943

A6NFV8

(UniProtKB/TrEmbl/P) Details

Dysbindin

Q9Y4B6

Interaction Score

0.941

Q0VGE8

(UniProtKB/Swiss-Prot/P) Details

Zinc finger protein 816

Q9Y4B6

Interaction Score

0.94

K4DI93

(UniProtKB/TrEmbl/P) Details

Cullin 4B, isoform CRA_e

Q9Y4B6

Interaction Score

0.94

Q6IT96

(UniProtKB/TrEmbl/P) Details

Histone deacetylase

Q9Y4B6

Interaction Score

0.94

Q05BZ6

(UniProtKB/TrEmbl/P) Details

HLTF protein

Q9Y4B6

Interaction Score

0.939

Q96CW1

(UniProtKB/Swiss-Prot/P) Details

AP-2 complex subunit mu

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.928	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.928	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Lysosomal membrane (GO:0005765)	0.928	Unknown: traceable author statement	GO	PubMed
Cytosol	Endolysosome membrane (GO:0036020)	0.928	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endocytic vesicle membrane (GO:0030666)	0.657	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Clathrin-coated endocytic vesicle (GO:0045334)	0.657	Unknown: non-traceable author statement	GO	PubMed
Secretory-pathway	Clathrin-coated endocytic vesicle membrane (GO:0030669)	0.657	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	AP-2 adaptor complex (GO:0030122)	0.972	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.972	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.972	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.928	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y4B6

Interaction Score

0.938

C9JVE2

(UniProtKB/TrEmbl/P) Details

DCN1-like protein

Q9Y4B6

Interaction Score

0.938

A0PJJ0

(UniProtKB/TrEmbl/P) Details

LLGL2 protein

Q9Y4B6

Interaction Score

0.938

F2Z381

(UniProtKB/TrEmbl/P) Details

POU class 5 homeobox 1 transcript variant 6

Q9Y4B6

Interaction Score

0.938

M1S623

(UniProtKB/TrEmbl/P) Details

POU domain protein

Q9Y4B6

Interaction Score

0.938

H0Y4W6

(UniProtKB/TrEmbl/P) Details

Estrogen receptor

Q9Y4B6

Interaction Score

0.938

A8MUD9

(UniProtKB/TrEmbl/P) Details

60S ribosomal protein L7

Q9Y4B6

Interaction Score

0.931

P04629

(UniProtKB/Swiss-Prot/P) Details

High affinity nerve growth factor receptor

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Neuronal cell body (GO:0043025)	0.897	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.897	Unknown: unspecified method	The Human Protein Atlas	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.897	Unknown: unspecified method	The Human Protein Atlas	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.7	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.994	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.994	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Early endosome (GO:0005769)	0.994	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Late endosome membrane (GO:0031902)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Early endosome membrane (GO:0031901)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Late endosome (GO:0005770)	0.994	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Lysosome (GO:0005764)	0.897	Predicted: pTarget method	LOCATE	PubMed
Membrane	Dendrite (GO:0030425)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Axon (GO:0030424)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Receptor complex (GO:0043235)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y4B6

Interaction Score

0.92

A0A0A0MR50

(UniProtKB/TrEmbl/P) Details

Cullin-4A

Q9Y4B6

Interaction Score

0.91

Q5JR94

(UniProtKB/TrEmbl/P) Details

40S ribosomal protein S8

Q9Y4B6

Interaction Score

0.91

Q53ES5

(UniProtKB/TrEmbl/P) Details

MUS81 endonuclease homolog

Q9Y4B6

Interaction Score

0.902

Q5TB80

(UniProtKB/Swiss-Prot/P) Details

Centrosomal protein of 162 kDa

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Spindle (GO:0005819)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centriole (GO:0005814)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Axonemal microtubule (GO:0005879)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

Q9Y4B6

Interaction Score

0.902

P0DN76

(UniProtKB/Swiss-Prot/P) Details

Splicing factor U2AF 35 kDa subunit-like protein

Q9Y4B6

Interaction Score

0.86

P42566

(UniProtKB/Swiss-Prot/P) Details

Epidermal growth factor receptor substrate 15

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Coated pit (GO:0005905)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Aggresome (GO:0016235)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Early endosome membrane (GO:0031901)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Cilium membrane (GO:0060170)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.999	Experimental: experimental	eSLDB	PubMed
Membrane	Membrane (GO:0016020)	0.999	Unknown: HDA	GO	PubMed
Membrane	AP-2 adaptor complex (GO:0030122)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Experimental: experimental	Organelle	PubMed
Membrane	Apical plasma membrane (GO:0016324)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Basal plasma membrane (GO:0009925)	0.999	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y4B6

Interaction Score

0.86

Q9HCE1

(UniProtKB/Swiss-Prot/P) Details

Putative helicase MOV-10

Q9Y4B6

Interaction Score

0.858

Q9BVG8

(UniProtKB/Swiss-Prot/P) Details

Kinesin-like protein KIFC3

Q9Y4B6

Interaction Score

0.858

P50914

(UniProtKB/Swiss-Prot/P) Details

60S ribosomal protein L14

Q9Y4B6

Interaction Score

0.836

P04004

(UniProtKB/Swiss-Prot/P) Details

Vitronectin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.996	Experimental: experimental	eSLDB	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.972	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.972	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.996	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Rough endoplasmic reticulum lumen (GO:0048237)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi lumen (GO:0005796)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.999	Experimental: experimental	eSLDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.999	Unknown: non-traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.999	Predicted: pTarget method	LOCATE	PubMed
Extracellular	Extracellular region (GO:0005576)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.999	Unknown: HDA	GO	PubMed
Extracellular	Blood microparticle (GO:0072562)	0.999	Unknown: HDA	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.999	Experimental: experimental	MatrixDB	PubMed
Extracellular	Basement membrane (GO:0005604)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Membrane (GO:0016020)	0.86	Experimental: experimental	MatrixDB	PubMed
Membrane	Alphav-beta3 integrin-vitronectin complex (GO:0071062)	0.86	Unknown: traceable author statement	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.972	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y4B6

Interaction Score

0.826

J3QRV5

(UniProtKB/TrEmbl/P) Details

Lethal(2) giant larvae protein homolog 2

Q9Y4B6

Interaction Score

0.826

Q8N441

(UniProtKB/Swiss-Prot/P) Details

Fibroblast growth factor receptor-like 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.998	Experimental: experimental	eSLDB	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.998	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.998	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Transport vesicle (GO:0030133)	0.998	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.998	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.998	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Vesicle (GO:0031982)	0.96	Experimental: experimental	eSLDB	PubMed
Membrane	Cell-cell contact zone (GO:0044291)	0.998	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y4B6

Interaction Score

0.808

Q5JR04

(UniProtKB/TrEmbl/P) Details

Mov10, Moloney leukemia virus 10, homolog (Mouse), isoform CRA_a

Q9Y4B6

Interaction Score

0.806

Q9Y2J2

(UniProtKB/Swiss-Prot/P) Details

Band 4.1-like protein 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.937	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.937	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.937	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Postsynaptic density (GO:0014069)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Juxtaparanode region of axon (GO:0044224)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Paranode region of axon (GO:0033270)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Axolemma (GO:0030673)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Cell-cell junction (GO:0005911)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

Q9Y4B6

Interaction Score

0.8

A0A2R8YCS7

(UniProtKB/TrEmbl/P) Details

Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

Q9Y4B6

Interaction Score

0.8

D6RAX7

(UniProtKB/TrEmbl/P) Details

COP9 constitutive photomorphogenic-like protein subunit 4 isoform 2

Q9Y4B6

Interaction Score

0.8

A0A087X1P5

(UniProtKB/TrEmbl/P) Details

COP9 signalosome complex subunit 7b

Q9Y4B6

Interaction Score

0.8

J3KQ34

(UniProtKB/TrEmbl/P) Details

COP9 signalosome complex subunit 7b

Q9Y4B6

Interaction Score

0.8

J3KQ41

(UniProtKB/TrEmbl/P) Details

COP9 signalosome complex subunit 7b

Q9Y4B6

Interaction Score

0.8

A0A087WT22

(UniProtKB/TrEmbl/P) Details

Cellular tumor antigen p53

Q9Y4B6

Interaction Score

0.8

A0A087WXZ1

(UniProtKB/TrEmbl/P) Details

Cellular tumor antigen p53

Q9Y4B6

Interaction Score

0.8

A0A087X1Q1

(UniProtKB/TrEmbl/P) Details

Cellular tumor antigen p53

Q9Y4B6

Interaction Score

0.8

A0A2R8YD63

(UniProtKB/TrEmbl/P) Details

DNA topoisomerase 2-binding protein 1

Q9Y4B6

Interaction Score

0.8

A7E2X7

(UniProtKB/TrEmbl/P) Details

Topoisomerase (DNA) II binding protein 1

Q9Y4B6

Interaction Score

0.8

B4E0K5

(UniProtKB/TrEmbl/P) Details

Mitogen-activated protein kinase

Q9Y4B6

Interaction Score

0.8

Q5T170

(UniProtKB/TrEmbl/P) Details

Pygopus homolog 2 (Drosophila), isoform CRA_a

Q9Y4B6

Interaction Score

0.8

A0A0C4DGA6

(UniProtKB/TrEmbl/P) Details

Helicase-like transcription factor

Q9Y4B6

Interaction Score

0.8

Q53Y49

(UniProtKB/TrEmbl/P) Details

FOXM1C

Q9Y4B6

Interaction Score

0.783

A0A0C4DFP5

(UniProtKB/TrEmbl/P) Details

Nuclear receptor ROR-alpha

Q9Y4B6

Interaction Score

0.783

A0A0A0MRM8

(UniProtKB/TrEmbl/P) Details

Unconventional myosin-VI

Q9Y4B6

Interaction Score

0.757

P61313

(UniProtKB/Swiss-Prot/P) Details

60S ribosomal protein L15

Q9Y4B6

Interaction Score

0.721

Q9HD64

(UniProtKB/Swiss-Prot/P) Details

X antigen family member 1

Q9Y4B6

Interaction Score

0.7

Q7Z780

(UniProtKB/TrEmbl/P) Details

U2 small nuclear RNA auxiliary factor 1

Q9Y4B6

Interaction Score

0.7

A0AV47

(UniProtKB/TrEmbl/P) Details

Topoisomerase (DNA) II binding protein 1

Q9Y4B6

Interaction Score

0.7

Q05BV8

(UniProtKB/TrEmbl/P) Details

TOPBP1 protein

Q9Y4B6

Interaction Score

0.7

Q8TBK5

(UniProtKB/TrEmbl/P) Details

60S ribosomal protein L6

Q9Y4B6

Interaction Score

0.688

A0A087WYP9

(UniProtKB/TrEmbl/P) Details

Dysbindin

Q9Y4B6

Interaction Score

0.688

D6RJC6

(UniProtKB/TrEmbl/P) Details

Dysbindin

Q9Y4B6

Interaction Score

0.688

A8K7B7

(UniProtKB/TrEmbl/P) Details

Protein phosphatase 2 (Formerly 2A), regulatory subunit A (PR 65), alpha isoform

Q9Y4B6

Interaction Score

0.688

B3KQV6

(UniProtKB/TrEmbl/P) Details

cDNA FLJ33169 fis, clone ADRGL2000384, highly similar to Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

Q9Y4B6

Interaction Score

0.688

A0PJ49

(UniProtKB/TrEmbl/P) Details

FGFRL1 protein

Q9Y4B6

Interaction Score

0.602

Q59H15

(UniProtKB/TrEmbl/P) Details

SAM domain-and HD domain-containing protein 1 variant

Q9Y4B6

Interaction Score

0.602

Q6ZTQ7

(UniProtKB/TrEmbl/P) Details

cDNA FLJ44352 fis, clone TRACH3006412, highly similar to Homo sapiens COP9 constitutive photomorphogenic homolog subunit 7B

Q9Y4B6

Interaction Score

0.602

A0A0A0MRA8

(UniProtKB/TrEmbl/P) Details

Band 4.1-like protein 3

Q9Y4B6

Interaction Score

0.602

A8MST6

(UniProtKB/TrEmbl/P) Details

Centrosomal protein of 78 kDa

Q9Y4B6

Interaction Score

E9PFW3

(UniProtKB/TrEmbl/P) Details

AP-2 complex subunit mu

Q9Y4B6

Interaction Score

A8K968

(UniProtKB/TrEmbl/P) Details

Band 4.1-like protein 3

Q9Y4B6

Interaction Score

X5DR71

(UniProtKB/TrEmbl/P) Details

Tyrosine-protein kinase receptor

Q9Y4B6

Interaction Score

Q9NZE8

(UniProtKB/Swiss-Prot/P) Details

39S ribosomal protein L35, mitochondrial

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Q9Y4B6

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

Q9Y4B6

O14746

Telomerase reverse transcriptase

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9Y4B6

P04637

Cellular tumor antigen p53

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9Y4B6

Q8IY92

Structure-specific endonuclease subunit SLX4

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9Y4B6

P03372

Estrogen receptor

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9Y4B6

P07992

DNA excision repair protein ERCC-1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9Y4B6

P19338

Nucleolin

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9Y4B6

Q92547

DNA topoisomerase 2-binding protein 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9Y4B6

Q13547

Histone deacetylase 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9Y4B6

O15379

Histone deacetylase 3

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9Y4B6

P78527

DNA-dependent protein kinase catalytic subunit

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9Y4B6

O95071

E3 ubiquitin-protein ligase UBR5

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9Y4B6

Q01081

Splicing factor U2AF 35 kDa subunit

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9Y4B6