Q9Y573

Actin-binding protein IPP    //   UniProt Profile 

Custom Settings: Use these controls to filter the data displayed on this page. The parameters apply to both the query protein and its interactors. Details







The (filtered) results are available for download, see the help for details. Download The Results

Species

 H. sapiens

Number of Interactions

 16 / 29

Average Interaction Score

 0.727

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cul3-RING ubiquitin ligase complex (GO:0031463) 0.997 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.997 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.997 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.997 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytoskeleton (GO:0005856) 0.997 Experimental: experimental Organelle PubMed 
Cytosol Actin cytoskeleton (GO:0015629) 0.997 Unknown: traceable author statement GO PubMed 

First-Neighbour Network Visualization

Toggle Display

The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.


Interactions

All Details

Q9Y573

Interaction Score
0.997

Q9H0H5

(UniProtKB/Swiss-Prot/P) Details

Rac GTPase-activating protein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Midbody (GO:0030496) 0.972 Experimental: inferred from direct assay GO PubMed 
Membrane Flemming body (GO:0090543) 0.972 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cleavage furrow (GO:0032154) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Unknown: traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Human Proteinpedia PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.86 Experimental: experimental eSLDB PubMed 
Secretory-pathway Acrosomal vesicle (GO:0001669) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 1 Experimental: experimental eSLDB PubMed 
Cytosol Centralspindlin complex (GO:0097149) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Mitotic spindle (GO:0072686) 1 Experimental: inferred from mutant phenotype GO PubMed 
Cytosol Spindle midzone (GO:0051233) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Microtubule (GO:0005874) 1 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Extrinsic to internal side of plasma membrane (GO:0031234) 0.972 Experimental: inferred from direct assay GO PubMed 
Cytosol Vesicle (GO:0031982) 1 Experimental: experimental eSLDB PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 1 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9Y573

Interaction Score
0.997

Q9Y2M5

(UniProtKB/Swiss-Prot/P) Details

Kelch-like protein 20

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cul3-RING ubiquitin ligase complex (GO:0031463) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 1 Unknown: inferred from electronic annotation GO PubMed 
Nucleus PML body (GO:0016605) 0.8 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.992 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.992 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Trans-Golgi network (GO:0005802) 0.992 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 1 Experimental: experimental Organelle PubMed 
Cytosol Actin cytoskeleton (GO:0015629) 1 Unknown: traceable author statement GO PubMed 
Membrane Dendrite (GO:0030425) 0.51 Unknown: inferred from electronic annotation GO PubMed 
Membrane Axon (GO:0030424) 0.51 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9Y573

Interaction Score
0.997

Q9GZZ9

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin-like modifier-activating enzyme 5

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.3 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9Y573

Interaction Score
0.997

Q86UX7

(UniProtKB/Swiss-Prot/P) Details

Fermitin family homolog 3

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.8 Experimental: experimental Human Proteinpedia PubMed 
Secretory-pathway Platelet alpha granule lumen (GO:0031093) 0.3 Unknown: traceable author statement GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 1 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Podosome (GO:0002102) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Cell projection (GO:0042995) 0.986 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.86 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.86 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.986 Experimental: experimental eSLDB PubMed 
Membrane Membrane (GO:0016020) 0.986 Unknown: HDA GO PubMed 
Membrane Membrane (GO:0016020) 0.986 Experimental: experimental MatrixDB PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 1 Unknown: HDA GO PubMed 
Membrane Cell junction (GO:0030054) 0.986 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9Y573

Interaction Score
0.997

Q9P1Z2

(UniProtKB/Swiss-Prot/P) Details

Calcium-binding and coiled-coil domain-containing protein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.992 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.992 Experimental: experimental Human Proteinpedia PubMed 
Nucleus Nucleus (GO:0005634) 0.992 Predicted: pTarget method LOCATE PubMed 
Nucleus Nuclear chromatin (GO:0000790) 0.992 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed 

Q9Y573

Interaction Score
0.997

Q13618

(UniProtKB/Swiss-Prot/P) Details

Cullin-3

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cul3-RING ubiquitin ligase complex (GO:0031463) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytosol (GO:0005829) 1 Unknown: traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 0.937 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.937 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.937 Unknown: traceable author statement GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.86 Experimental: experimental eSLDB PubMed 
Secretory-pathway Golgi membrane (GO:0000139) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Polar microtubule (GO:0005827) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Sperm flagellum (GO:0036126) 0.86 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.86 Unknown: HDA GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 1 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9Y573

Interaction Score
0.996

O00487

(UniProtKB/Swiss-Prot/P) Details

26S proteasome non-ATPase regulatory subunit 14

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.998 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytosol (GO:0005829) 0.998 Unknown: traceable author statement GO PubMed 
Cytosol Proteasome complex (GO:0000502) 0.998 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosolic proteasome complex (GO:0031597) 0.998 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Proteasome accessory complex (GO:0022624) 0.998 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Proteasome regulatory particle, lid subcomplex (GO:0008541) 0.998 Experimental: inferred from mutant phenotype GO PubMed 
Nucleus Nucleus (GO:0005634) 0.902 Unknown: HDA GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.902 Unknown: traceable author statement GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.902 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Secretory granule lumen (GO:0034774) 0.3 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.3 Unknown: traceable author statement GO PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9Y573

Interaction Score
0.992

Q9NXS3

(UniProtKB/Swiss-Prot/P) Details

Kelch-like protein 28

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cul3-RING ubiquitin ligase complex (GO:0031463) 0.995 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.995 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.995 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.995 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9Y573

Interaction Score
0.989

O43813

(UniProtKB/Swiss-Prot/P) Details

LanC-like protein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.992 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.992 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.992 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: pTarget method LOCATE PubMed 
Cytosol Microtubule cytoskeleton (GO:0015630) 0.992 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.998 Experimental: experimental eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.998 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.998 Experimental: experimental Organelle PubMed 
Membrane Integral to plasma membrane (GO:0005887) 0.998 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9Y573

Interaction Score
0.938

J3KNY7

(UniProtKB/TrEmbl/P) Details

BTB (POZ) domain containing 5, isoform CRA_d

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.94 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytosol (GO:0005829) 0.94 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9Y573

Interaction Score
0.938

P49917

(UniProtKB/Swiss-Prot/P) Details

DNA ligase 4

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.94 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Nonhomologous end joining complex (GO:0070419) 0.94 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus DNA ligase IV complex (GO:0032807) 1 Experimental: inferred from mutant phenotype GO PubMed 
Nucleus DNA-dependent protein kinase-DNA ligase 4 complex (GO:0005958) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Nucleus Nuclear chromosome, telomeric region (GO:0000784) 1 Unknown: inferred by curator GO PubMed 
Nucleus Condensed chromosome (GO:0000793) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9Y573

Interaction Score
0.798

Q53TN2

(UniProtKB/TrEmbl/P) Details

LanC lantibiotic synthetase component C-like 1 (Bacterial), isoform CRA_a

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.8 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: pTarget method LOCATE PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9Y573

Interaction Score
0

A0A0C4DGV9

(UniProtKB/TrEmbl/P) Details

DNA ligase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleoplasm (GO:0005654) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9Y573

Interaction Score
0

A0AV05

(UniProtKB/TrEmbl/P) Details

Zinc finger protein 517

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9Y573

Interaction Score
0

Q05D32

(UniProtKB/Swiss-Prot/P) Details

CTD small phosphatase-like protein 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.988 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.988 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.988 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9Y573

Interaction Score
0

Q6ZMY9

(UniProtKB/Swiss-Prot/P) Details

Zinc finger protein 517

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.987 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.987 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.987 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.987 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

⇦ Back to the Search Page
⇦ Back to Starting Page

ComPPI is published in Nucleic Acids Research Database Issue 2015