A2RU14

Transmembrane protein 218    //   UniProt Profile 

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Species

 H. sapiens

Number of Interactions

 59 / 61

Average Interaction Score

 0.939

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Cilium (GO:0005929) 0.971 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.971 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.971 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.971 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.


Interactions

All Details

A2RU14

Interaction Score
0.998

P41181

(UniProtKB/Swiss-Prot/P) Details

Aquaporin-2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.992 Experimental: experimental eSLDB PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.657 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Recycling endosome (GO:0055037) 0.657 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Transport vesicle membrane (GO:0030658) 0.657 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Integral to membrane (GO:0016021) 1 Experimental: experimental eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: pTarget method LOCATE PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to plasma membrane (GO:0005887) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Apical plasma membrane (GO:0016324) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Basolateral plasma membrane (GO:0016323) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Vesicle (GO:0031982) 0.992 Experimental: experimental eSLDB PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.992 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.997

P16410

(UniProtKB/Swiss-Prot/P) Details

Cytotoxic T-lymphocyte protein 4

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.988 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 0.8 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.988 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Clathrin-coated endocytic vesicle (GO:0045334) 0.988 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to membrane (GO:0016021) 0.999 Experimental: experimental eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.999 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.999 Experimental: experimental Organelle PubMed 
Membrane External side of plasma membrane (GO:0009897) 0.999 Experimental: inferred from direct assay GO PubMed 
Membrane Integral to plasma membrane (GO:0005887) 0.999 Experimental: inferred from mutant phenotype GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.997

P11912

(UniProtKB/Swiss-Prot/P) Details

B-cell antigen receptor complex-associated protein alpha chain

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane B cell receptor complex (GO:0019815) 0.999 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: inferred from biological aspect of ancestor GO PubMed 
Secretory-pathway Multivesicular body (GO:0005771) 0.7 Predicted: inferred from sequence or structural similarity GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to membrane (GO:0016021) 0.999 Experimental: experimental eSLDB PubMed 
Membrane Membrane raft (GO:0045121) 0.999 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.999 Unknown: traceable author statement GO PubMed 
Membrane External side of plasma membrane (GO:0009897) 0.999 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Integral to plasma membrane (GO:0005887) 0.999 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.996

Q9BQ51

(UniProtKB/Swiss-Prot/P) Details

Programmed cell death 1 ligand 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Endomembrane system (GO:0012505) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytosol (GO:0005829) 0.86 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.958 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.958 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.958 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Membrane (GO:0016020) 0.98 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.98 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.98 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.98 Unknown: traceable author statement GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.995

P57739

(UniProtKB/Swiss-Prot/P) Details

Claudin-2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleoplasm (GO:0005654) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Cytoskeleton (GO:0005856) 0.8 Experimental: experimental eSLDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.994 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.994 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.994 Unknown: inferred from electronic annotation GO PubMed 
Membrane Cell junction (GO:0030054) 0.994 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Tight junction (GO:0005923) 0.994 Predicted: inferred from sequence or structural similarity GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.995

Q96BA8

(UniProtKB/Swiss-Prot/P) Details

Cyclic AMP-responsive element-binding protein 3-like protein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.94 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.995 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.995 Predicted: inferred from sequence or structural similarity GO PubMed 
Nucleus Nucleus (GO:0005634) 0.995 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.86 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Lysosome (GO:0005764) 0.94 Predicted: pTarget method LOCATE PubMed 
Nucleus Nuclear chromatin (GO:0000790) 0.995 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.972 Experimental: inferred from direct assay GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.972 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.972 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.994

Q96FE7

(UniProtKB/Swiss-Prot/P) Details

Phosphoinositide-3-kinase-interacting protein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: pTarget method LOCATE PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Membrane (GO:0016020) 0.971 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.971 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.971 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.971 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.993

A2A2Y4

(UniProtKB/Swiss-Prot/P) Details

FERM domain-containing protein 3

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Cytoskeleton (GO:0005856) 0.91 Predicted: inferred from biological aspect of ancestor GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.958 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.958 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.958 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.993

Q3SXY8

(UniProtKB/Swiss-Prot/P) Details

ADP-ribosylation factor-like protein 13B

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.979 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 0.979 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.979 Unknown: unspecified method The Human Protein Atlas PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.982 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.982 Experimental: experimental Human Proteinpedia PubMed 
Nucleus Nucleus (GO:0005634) 0.982 Predicted: pTarget method LOCATE PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Microtubule cytoskeleton (GO:0015630) 0.979 Unknown: unspecified method The Human Protein Atlas PubMed 
Cytosol Axoneme (GO:0005930) 0.979 Unknown: inferred from electronic annotation GO PubMed 
Membrane Cilium (GO:0005929) 0.937 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Cilium membrane (GO:0060170) 0.937 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Motile cilium (GO:0031514) 0.937 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.992

P19397

(UniProtKB/Swiss-Prot/P) Details

Leukocyte surface antigen CD53

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Cell surface (GO:0009986) 1 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Tertiary granule membrane (GO:0070821) 0.3 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Experimental: experimental eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane Immunological synapse (GO:0001772) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Integral to plasma membrane (GO:0005887) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.3 Unknown: HDA GO PubMed 
Membrane Cell-cell junction (GO:0005911) 1 Predicted: inferred from sequence or structural similarity GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.992

O95452

(UniProtKB/Swiss-Prot/P) Details

Gap junction beta-6 protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.999 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.999 Predicted: pTarget method LOCATE PubMed 
Membrane Connexon complex (GO:0005922) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Membrane Apical plasma membrane (GO:0016324) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Membrane Cell junction (GO:0030054) 0.999 Experimental: inferred from direct assay GO PubMed 
Membrane Cell junction (GO:0030054) 0.999 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.991

Q6ZS10

(UniProtKB/Swiss-Prot/P) Details

C-type lectin domain family 17, member A

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Cell surface (GO:0009986) 0.972 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.972 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.972 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.991

Q6PEY1

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 88

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.8 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.958 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.958 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.958 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.989

P43628

(UniProtKB/Swiss-Prot/P) Details

Killer cell immunoglobulin-like receptor 2DL3

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.94 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to membrane (GO:0016021) 0.986 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.986 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.986 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.986 Experimental: experimental Organelle PubMed 
Membrane Integral to plasma membrane (GO:0005887) 0.986 Unknown: traceable author statement GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.989

Q96BI3

(UniProtKB/Swiss-Prot/P) Details

Gamma-secretase subunit APH-1A

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Endoplasmic reticulum (GO:0005783) 1 Experimental: experimental eSLDB PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 1 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 1 Experimental: experimental eSLDB PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Golgi cisterna membrane (GO:0032580) 1 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.999 Unknown: HDA GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.999 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.999 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.999 Unknown: traceable author statement GO PubMed 
Membrane Gamma-secretase complex (GO:0070765) 0.999 Experimental: inferred from direct assay GO PubMed 
Membrane Integral to plasma membrane (GO:0005887) 0.999 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.989

Q9UGN4

(UniProtKB/Swiss-Prot/P) Details

CMRF35-like molecule 8

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.79 Predicted: SVM decision tree eSLDB PubMed 
Secretory-pathway Tertiary granule membrane (GO:0070821) 0.79 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Membrane (GO:0016020) 0.971 Experimental: inferred from direct assay GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.971 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.971 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.971 Unknown: traceable author statement GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.3 Unknown: HDA GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.989

Q8IUN9

(UniProtKB/Swiss-Prot/P) Details

C-type lectin domain family 10 member A

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.999 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.999 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.999 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.999 Predicted: pTarget method LOCATE PubMed 
Membrane Plasma membrane (GO:0005886) 0.999 Experimental: experimental Organelle PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.989

Q9NTQ9

(UniProtKB/Swiss-Prot/P) Details

Gap junction beta-4 protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.96 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleolus (GO:0005730) 0.96 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.999 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.999 Predicted: pTarget method LOCATE PubMed 
Membrane Connexon complex (GO:0005922) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Membrane Cell junction (GO:0030054) 0.999 Experimental: inferred from direct assay GO PubMed 
Membrane Cell junction (GO:0030054) 0.999 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.989

Q15125

(UniProtKB/Swiss-Prot/P) Details

3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nuclear envelope (GO:0005635) 0.8 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.999 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.999 Experimental: experimental Organelle PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.999 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.999 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 0.999 Unknown: traceable author statement GO PubMed 
Cytosol Peroxisome (GO:0005777) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Cytoplasmic vesicle (GO:0031410) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.958 Predicted: SVM decision tree eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.958 Experimental: experimental Organelle PubMed 
Membrane Integral to plasma membrane (GO:0005887) 0.958 Unknown: traceable author statement GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.989

Q9BZJ8

(UniProtKB/Swiss-Prot/P) Details

G-protein coupled receptor 61

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Endosome (GO:0005768) 0.86 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endosome membrane (GO:0010008) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.998 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.998 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.998 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.998 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Receptor complex (GO:0043235) 0.998 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.988

Q13520

(UniProtKB/Swiss-Prot/P) Details

Aquaporin-6

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Cytoplasmic vesicle membrane (GO:0030659) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.996 Predicted: SVM decision tree eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.996 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 0.996 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to plasma membrane (GO:0005887) 0.996 Unknown: traceable author statement GO PubMed 
Membrane Apical plasma membrane (GO:0016324) 0.996 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.988

P08034

(UniProtKB/Swiss-Prot/P) Details

Gap junction beta-1 protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 0.3 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.996 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.996 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.996 Predicted: pTarget method LOCATE PubMed 
Membrane Plasma membrane (GO:0005886) 0.996 Experimental: experimental Organelle PubMed 
Membrane Lateral plasma membrane (GO:0016328) 0.996 Unknown: inferred from electronic annotation GO PubMed 
Membrane Connexon complex (GO:0005922) 0.996 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.987

P34981

(UniProtKB/Swiss-Prot/P) Details

Thyrotropin-releasing hormone receptor

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.994 Experimental: experimental eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.994 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.994 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 0.994 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to plasma membrane (GO:0005887) 0.994 Unknown: traceable author statement GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.987

P54849

(UniProtKB/Swiss-Prot/P) Details

Epithelial membrane protein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleoplasm (GO:0005654) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.994 Unknown: traceable author statement GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.994 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.994 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.994 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.994 Predicted: pTarget method LOCATE PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.987

Q96CE8

(UniProtKB/Swiss-Prot/P) Details

Transmembrane 4 L6 family member 18

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.3 Unknown: unspecified method The Human Protein Atlas PubMed 
Nucleus Nucleolus (GO:0005730) 0.3 Unknown: unspecified method The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.982 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.982 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.982 Predicted: pTarget method LOCATE PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.986

O95279

(UniProtKB/Swiss-Prot/P) Details

Potassium channel subfamily K member 5

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.992 Experimental: experimental eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.992 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 0.992 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to plasma membrane (GO:0005887) 0.992 Unknown: traceable author statement GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.986

P48051

(UniProtKB/Swiss-Prot/P) Details

G protein-activated inward rectifier potassium channel 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Golgi apparatus (GO:0005794) 0.3 Unknown: HDA GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Voltage-gated potassium channel complex (GO:0008076) 0.991 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.991 Unknown: HDA GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.991 Predicted: pTarget method LOCATE PubMed 
Membrane Plasma membrane (GO:0005886) 0.991 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 0.991 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.986

Q9H7M9

(UniProtKB/Swiss-Prot/P) Details

V-type immunoglobulin domain-containing suppressor of T-cell activation

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to membrane (GO:0016021) 0.972 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.972 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.972 Experimental: experimental Human Proteinpedia PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.986

Q9Y4D2

(UniProtKB/Swiss-Prot/P) Details

Sn1-specific diacylglycerol lipase alpha

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Varicosity (GO:0043196) 0.971 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to membrane (GO:0016021) 0.971 Predicted: SVM decision tree eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.971 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.971 Experimental: experimental Human Proteinpedia PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.985

Q3KNW5

(UniProtKB/Swiss-Prot/P) Details

Solute carrier family 10 member 6

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.987 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.987 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.987 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.987 Predicted: pTarget method LOCATE PubMed 
Membrane Plasma membrane (GO:0005886) 0.987 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.983

Q8TDT2

(UniProtKB/Swiss-Prot/P) Details

Probable G-protein coupled receptor 152

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.982 Experimental: experimental eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.982 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to plasma membrane (GO:0005887) 0.982 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.982

Q8TB36

(UniProtKB/Swiss-Prot/P) Details

Ganglioside-induced differentiation-associated protein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.988 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.988 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.988 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.992 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.992 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Mitochondrion Integral to mitochondrial outer membrane (GO:0031307) 0.992 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.3 Unknown: HDA GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.79 Unknown: HDA GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.79 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.981

Q4KMG9

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 52B

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.958 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.958 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.3 Unknown: HDA GO PubMed 
Membrane Focal adhesion (GO:0005925) 0.958 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.975

P47884

(UniProtKB/Swiss-Prot/P) Details

Olfactory receptor 1D4

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.958 Predicted: SVM decision tree eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.958 Experimental: experimental Organelle PubMed 
Membrane Integral to plasma membrane (GO:0005887) 0.958 Unknown: traceable author statement GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.975

Q9BVX2

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 106C

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
N/A Cellular component (GO:0005575) 0.3 Unknown: no biological data available GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.86 Experimental: experimental eSLDB PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.958 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.958 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.958 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.973

Q9Y282

(UniProtKB/Swiss-Prot/P) Details

Endoplasmic reticulum-Golgi intermediate compartment protein 3

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.986 Experimental: experimental eSLDB PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 0.986 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Endoplasmic reticulum-Golgi intermediate compartment membrane (GO:0033116) 0.986 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.986 Experimental: experimental eSLDB PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.986 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.853 Unknown: HDA GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.853 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.853 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.97

Q86VR2

(UniProtKB/Swiss-Prot/P) Details

Reticulophagy regulator 3

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nuclear membrane (GO:0031965) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.79 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.79 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.97

Q6ZP80

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 182

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.79 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.79 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.959

Q8TED1

(UniProtKB/Swiss-Prot/P) Details

Probable glutathione peroxidase 8

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Secretory-pathway Endoplasmic reticulum lumen (GO:0005788) 0.3 Unknown: traceable author statement GO PubMed 
Cytosol Actin cytoskeleton (GO:0015629) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to membrane (GO:0016021) 0.3 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.958

Q9NXB9

(UniProtKB/Swiss-Prot/P) Details

Elongation of very long chain fatty acids protein 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.987 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.987 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 0.987 Unknown: traceable author statement GO PubMed 
Secretory-pathway Integral to endoplasmic reticulum membrane (GO:0030176) 0.987 Predicted: inferred from biological aspect of ancestor GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.91 Predicted: SVM decision tree eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.91 Predicted: pTarget method LOCATE PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.953

O15342

(UniProtKB/Swiss-Prot/P) Details

V-type proton ATPase subunit e 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Endosome membrane (GO:0010008) 0.51 Unknown: traceable author statement GO PubMed 
Secretory-pathway Phagocytic vesicle membrane (GO:0030670) 0.51 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.897 Unknown: traceable author statement GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.897 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.897 Unknown: inferred from electronic annotation GO PubMed 
Membrane Proton-transporting V-type ATPase, V0 domain (GO:0033179) 0.897 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.953

Q96HJ5

(UniProtKB/Swiss-Prot/P) Details

Membrane-spanning 4-domains subfamily A member 3

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Perinuclear region of cytoplasm (GO:0048471) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.8 Experimental: experimental eSLDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.853 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.853 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.853 Unknown: traceable author statement GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.94

Q8N112

(UniProtKB/Swiss-Prot/P) Details

Leucine-rich single-pass membrane protein 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.86 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.86 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.933

Q53GL0

(UniProtKB/Swiss-Prot/P) Details

Pleckstrin homology domain-containing family O member 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.79 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.79 Predicted: PAML algorithm PA-GOSUB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.937 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.937 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.937 Predicted: pTarget method LOCATE PubMed 
Membrane Muscle cell projection membrane (GO:0036195) 0.51 Unknown: inferred from electronic annotation GO PubMed 
Membrane Ruffle membrane (GO:0032587) 0.51 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.928

P02545

(UniProtKB/Swiss-Prot/P) Details

Prelamin-A/C

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Endomembrane system (GO:0012505) 0.998 Experimental: experimental Organelle PubMed 
Cytosol Cytoplasm (GO:0005737) 0.998 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytosol (GO:0005829) 0.998 Unknown: traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Unknown: HDA GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Lamin filament (GO:0005638) 1 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nuclear membrane (GO:0031965) 1 Unknown: HDA GO PubMed 
Nucleus Nuclear envelope (GO:0005635) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear speck (GO:0016607) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 0.998 Experimental: experimental Organelle PubMed 
Extracellular Extracellular matrix (GO:0031012) 0.8 Experimental: experimental MatrixDB PubMed 
Cytosol Organelle inner membrane (GO:0019866) 0.998 Experimental: experimental Organelle PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.923

Q5T700

(UniProtKB/Swiss-Prot/P) Details

Low-density lipoprotein receptor class A domain-containing protein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.79 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.3 Unknown: unspecified method The Human Protein Atlas PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.79 Unknown: unspecified method The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to membrane (GO:0016021) 0.3 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.92

Q9GZR5

(UniProtKB/Swiss-Prot/P) Details

Elongation of very long chain fatty acids protein 4

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.998 Experimental: experimental eSLDB PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.998 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.998 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Integral to endoplasmic reticulum membrane (GO:0030176) 0.998 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.8 Experimental: experimental eSLDB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.92

Q8WUV1

(UniProtKB/TrEmbl/P) Details

Tetraspanin

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.8 Experimental: experimental eSLDB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.916

Q8WWF3

(UniProtKB/Swiss-Prot/P) Details

Serine-rich single-pass membrane protein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.79 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.79 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.916

Q6UWW9

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 207

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.79 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.79 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.908

Q9BZL3

(UniProtKB/Swiss-Prot/P) Details

Small integral membrane protein 3

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.3 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.883

O75889

(UniProtKB/TrEmbl/P) Details

Killer cell lectin-like receptor subfamily A, member 1, isoform CRA_a

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Integral to membrane (GO:0016021) 0.91 Predicted: SVM decision tree eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.91 Predicted: pTarget method LOCATE PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.806

Q5JX71

(UniProtKB/Swiss-Prot/P) Details

Protein FAM209A

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.3 Unknown: HDA GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.3 Unknown: HDA GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.799

Q8WWH4

(UniProtKB/Swiss-Prot/P) Details

Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.999 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Pi-body (GO:0071546) 0.999 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Cytosol (GO:0005829) 0.999 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.778

P12004

(UniProtKB/Swiss-Prot/P) Details

Proliferating cell nuclear antigen

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol PCNA complex (GO:0043626) 0.972 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nuclear body (GO:0016604) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear body (GO:0016604) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus PCNA-p21 complex (GO:0070557) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Centrosome (GO:0005813) 0.972 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear chromosome, telomeric region (GO:0000784) 1 Unknown: HDA GO PubMed 
Nucleus Nuclear replication fork (GO:0043596) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Replication fork (GO:0005657) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Replisome (GO:0030894) 1 Unknown: traceable author statement GO PubMed 
Nucleus DNA replication factor C complex (GO:0005663) 1 Unknown: traceable author statement GO PubMed 
Nucleus Chromatin (GO:0000785) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.972 Unknown: HDA GO PubMed 

Interaction Source Database:

IntAct, CCSB, BioGRID

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.752

Q9NR31

(UniProtKB/Swiss-Prot/P) Details

GTP-binding protein SAR1a

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.998 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.94 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.998 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.998 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.998 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Golgi membrane (GO:0000139) 0.998 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway COPII vesicle coat (GO:0030127) 0.998 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.64

A0A0S2Z4U3

(UniProtKB/TrEmbl/P) Details

Syndecan

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.56

Q6PL24

(UniProtKB/Swiss-Prot/P) Details

Protein TMED8

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

A2RU14

Interaction Score
0.56

Q5TCI8

(UniProtKB/TrEmbl/P) Details

Prelamin-A/C

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

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ComPPI is published in Nucleic Acids Research Database Issue 2015