Q13520

Aquaporin-6 // UniProt Profile

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Species	H. sapiens
Number of Interactions	221 / 223
Average Interaction Score	0.928

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Cytoplasmic vesicle membrane (GO:0030659)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.996	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.996	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	0.996	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	0.996	Unknown: traceable author statement	GO	PubMed
Membrane	Apical plasma membrane (GO:0016324)	0.996	Predicted: inferred from biological aspect of ancestor	GO	PubMed

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Interactions

All Details

Q13520

Interaction Score

0.999

P02786

(UniProtKB/Swiss-Prot/P) Details

Transferrin receptor protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Cell surface (GO:0009986)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Coated pit (GO:0005905)	0.994	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.994	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Recycling endosome (GO:0055037)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Early endosome (GO:0005769)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endosome membrane (GO:0010008)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Lysosome (GO:0005764)	0.994	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Melanosome (GO:0042470)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Clathrin coated vesicle membrane (GO:0030665)	1	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.98	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.98	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.98	Unknown: HDA	GO	PubMed
Extracellular	Blood microparticle (GO:0072562)	0.98	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	1	Unknown: non-traceable author statement	GO	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: pTarget method	LOCATE	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	External side of plasma membrane (GO:0009897)	1	Experimental: inferred from genetic interaction	GO	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Experimental: inferred from genetic interaction	GO	PubMed
Membrane	Basolateral plasma membrane (GO:0016323)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.994	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.999

P50281

(UniProtKB/Swiss-Prot/P) Details

Matrix metalloproteinase-14

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.8	Experimental: inferred from mutant phenotype	GO	PubMed
Secretory-pathway	Golgi lumen (GO:0005796)	0.98	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Macropinosome (GO:0044354)	0.98	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.98	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Melanosome (GO:0042470)	0.98	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Intermediate filament cytoskeleton (GO:0045111)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intermediate filament cytoskeleton (GO:0045111)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.998	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.998	Experimental: inferred from mutant phenotype	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.998	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.999	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Experimental: experimental	Organelle	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	0.999	Unknown: traceable author statement	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.999	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.999

P11215

(UniProtKB/Swiss-Prot/P) Details

Integrin alpha-M

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Tertiary granule membrane (GO:0070821)	0.3	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.988	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.988	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.988	Experimental: inferred from direct assay	GO	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: pTarget method	LOCATE	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	External side of plasma membrane (GO:0009897)	1	Unknown: non-traceable author statement	GO	PubMed
Membrane	Integrin complex (GO:0008305)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.3	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.999

P29972

(UniProtKB/Swiss-Prot/P) Details

Aquaporin-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Apical part of cell (GO:0045177)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.992	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear membrane (GO:0031965)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	Brush border (GO:0005903)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Brush border membrane (GO:0031526)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.988	Experimental: experimental	MatrixDB	PubMed
Extracellular	Symbiont-containing vacuole (GO:0020003)	0.988	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Symbiont-containing vacuole membrane (GO:0020005)	0.988	Experimental: inferred from direct assay	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: pTarget method	LOCATE	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Sarcolemma (GO:0042383)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Apical plasma membrane (GO:0016324)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Basolateral plasma membrane (GO:0016323)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Basal plasma membrane (GO:0009925)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.992	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.999

P52803

(UniProtKB/Swiss-Prot/P) Details

Ephrin-A5

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.972	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.972	Experimental: experimental	MatrixDB	PubMed
Extracellular	Basement membrane (GO:0005604)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Anchored to external side of plasma membrane (GO:0031362)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Caveola (GO:0005901)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Adherens junction (GO:0005912)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.999

Q9Y5Q5

(UniProtKB/Swiss-Prot/P) Details

Atrial natriuretic peptide-converting enzyme

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nuclear body (GO:0016604)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear body (GO:0016604)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	0.96	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.958	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.958	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.958	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.999

Q13277

(UniProtKB/Swiss-Prot/P) Details

Syntaxin-3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.902	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear body (GO:0016604)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Vacuole (GO:0005773)	0.902	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Melanosome (GO:0042470)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Specific granule (GO:0042581)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Zymogen granule membrane (GO:0042589)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Azurophil granule (GO:0042582)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Synaptic vesicle (GO:0008021)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Growth cone (GO:0030426)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Lamellipodium (GO:0030027)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Neuron projection (GO:0043005)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Dendrite (GO:0030425)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	SNARE complex (GO:0031201)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Apical plasma membrane (GO:0016324)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.902	Unknown: HDA	GO	PubMed
Membrane	Cell-cell junction (GO:0005911)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Presynaptic membrane (GO:0042734)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.999

P61266

(UniProtKB/Swiss-Prot/P) Details

Syntaxin-1B

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.657	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.91	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Synaptic vesicle (GO:0008021)	0.91	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Spindle (GO:0005819)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Axon (GO:0030424)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	SNARE complex (GO:0031201)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Neuromuscular junction (GO:0031594)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Presynaptic active zone membrane (GO:0048787)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.999

P07204

(UniProtKB/Swiss-Prot/P) Details

Thrombomodulin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.86	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Vacuolar membrane (GO:0005774)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.958	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.958	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.958	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Membrane (GO:0016020)	0.999	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.999	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Experimental: experimental	Organelle	PubMed
Membrane	Apicolateral plasma membrane (GO:0016327)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	0.999	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.999

O95183

(UniProtKB/Swiss-Prot/P) Details

Vesicle-associated membrane protein 5

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.987	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.8	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.987	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.987	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Late endosome (GO:0005770)	0.987	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle membrane (GO:0030659)	0.987	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Experimental: experimental	eSLDB	PubMed
Membrane	SNARE complex (GO:0031201)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Integral to organelle membrane (GO:0031301)	0.987	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Vesicle (GO:0031982)	0.987	Experimental: experimental	eSLDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.987	Unknown: HDA	GO	PubMed
Membrane	Intercalated disc (GO:0014704)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.999

Q7Z6L0

(UniProtKB/Swiss-Prot/P) Details

Proline-rich transmembrane protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Synaptic vesicle (GO:0008021)	0.79	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Synaptic vesicle membrane (GO:0030672)	0.79	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendritic spine (GO:0043197)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Postsynaptic density (GO:0014069)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Nerve terminal (GO:0043679)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Vesicle (GO:0031982)	0.7	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Presynaptic membrane (GO:0042734)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Postsynaptic membrane (GO:0045211)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.999

Q8TAC9

(UniProtKB/Swiss-Prot/P) Details

Secretory carrier-associated membrane protein 5

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: experimental	Human Proteinpedia	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: experimental	Human Proteinpedia	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Trans-Golgi network membrane (GO:0032588)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Recycling endosome membrane (GO:0055038)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Synaptic vesicle membrane (GO:0030672)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.999	Experimental: inferred from direct assay	GO	PubMed
Membrane	SNARE complex (GO:0031201)	0.999	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Predicted: pTarget method	LOCATE	PubMed
Membrane	Cell junction (GO:0030054)	0.999	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.999

P45844

(UniProtKB/Swiss-Prot/P) Details

ATP-binding cassette sub-family G member 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.8	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Unknown: HDA	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Recycling endosome (GO:0055037)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.999	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Unknown: HDA	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Predicted: pTarget method	LOCATE	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Experimental: experimental	Organelle	PubMed
Membrane	External side of plasma membrane (GO:0009897)	0.999	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.999

Q9H7V2

(UniProtKB/Swiss-Prot/P) Details

Synapse differentiation-inducing gene protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cell body (GO:0044297)	0.988	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.988	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Early endosome membrane (GO:0031901)	0.7	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Dendritic shaft (GO:0043198)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Dendritic spine (GO:0043197)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Postsynaptic density (GO:0014069)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Excitatory synapse (GO:0060076)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Postsynaptic membrane (GO:0045211)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.999

Q9H0Q3

(UniProtKB/Swiss-Prot/P) Details

FXYD domain-containing ion transport regulator 6

Q13520

Interaction Score

0.999

O00180

(UniProtKB/Swiss-Prot/P) Details

Potassium channel subfamily K member 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Perikaryon (GO:0043204)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.972	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.972	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Recycling endosome (GO:0055037)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Brush border membrane (GO:0031526)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendrite (GO:0030425)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Potassium channel complex (GO:0034705)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Voltage-gated potassium channel complex (GO:0008076)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: pTarget method	LOCATE	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Apical plasma membrane (GO:0016324)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Synapse (GO:0045202)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.999

Q99519

(UniProtKB/Swiss-Prot/P) Details

Sialidase-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Lysosome (GO:0005764)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Lysosome (GO:0005764)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Lysosome (GO:0005764)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Lysosomal lumen (GO:0043202)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Lysosomal membrane (GO:0005765)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Membrane (GO:0016020)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Vesicle (GO:0031982)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.999

O14493

(UniProtKB/Swiss-Prot/P) Details

Claudin-4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoskeleton (GO:0005856)	0.8	Experimental: experimental	eSLDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Chloride channel complex (GO:0034707)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: pTarget method	LOCATE	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Lateral plasma membrane (GO:0016328)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Apicolateral plasma membrane (GO:0016327)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Membrane	Apical plasma membrane (GO:0016324)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Basal plasma membrane (GO:0009925)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Tight junction (GO:0005923)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.999

O43752

(UniProtKB/Swiss-Prot/P) Details

Syntaxin-6

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.96	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Trans-Golgi network (GO:0005802)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Trans-Golgi network membrane (GO:0032588)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Early endosome (GO:0005769)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Phagocytic vesicle (GO:0045335)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Clathrin-coated vesicle (GO:0030136)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Integral to synaptic vesicle membrane (GO:0030285)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.998	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.998	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	SNARE complex (GO:0031201)	0.998	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.998	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.998	Experimental: experimental	Organelle	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.999

P60033

(UniProtKB/Swiss-Prot/P) Details

CD81 antigen

Q13520

Interaction Score

0.999

Q0VAQ4

(UniProtKB/Swiss-Prot/P) Details

Small cell adhesion glycoprotein

Q13520

Interaction Score

0.999

Q6UX40

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 107

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Midbody (GO:0030496)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Flemming body (GO:0090543)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytosol (GO:0005829)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Lysosome (GO:0005764)	0.94	Predicted: pTarget method	LOCATE	PubMed
Membrane	Ciliary transition zone (GO:0035869)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	TCTN-B9D complex (GO:0036038)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.999

Q9UHI5

(UniProtKB/Swiss-Prot/P) Details

Large neutral amino acids transporter small subunit 2

Q13520

Interaction Score

0.998

Q86Y82

(UniProtKB/Swiss-Prot/P) Details

Syntaxin-12

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Endomembrane system (GO:0012505)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Pre-autophagosomal structure (GO:0000407)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Cytosol	BLOC-1 complex (GO:0031083)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.996	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Recycling endosome membrane (GO:0055038)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Early endosome membrane (GO:0031901)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Phagocytic vesicle (GO:0045335)	0.996	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.998	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.998	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Membrane raft (GO:0045121)	0.998	Experimental: inferred from direct assay	GO	PubMed
Membrane	SNARE complex (GO:0031201)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Vesicle (GO:0031982)	1	Experimental: inferred from mutant phenotype	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.998

Q9P0L0

(UniProtKB/Swiss-Prot/P) Details

Vesicle-associated membrane protein-associated protein A

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.994	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.86	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nuclear membrane (GO:0031965)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.996	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum exit site (GO:0070971)	0.996	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.996	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.994	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.997	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.997	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.997	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Vesicle (GO:0031982)	0.994	Experimental: inferred from direct assay	GO	PubMed
Membrane	Tight junction (GO:0005923)	0.997	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.998

Q8TBE7

(UniProtKB/Swiss-Prot/P) Details

Solute carrier family 35 member G2

Q13520

Interaction Score

0.998

P21145

(UniProtKB/Swiss-Prot/P) Details

Myelin and lymphocyte protein

Q13520

Interaction Score

0.998

Q9UBY5

(UniProtKB/Swiss-Prot/P) Details

Lysophosphatidic acid receptor 3

Q13520

Interaction Score

0.998

Q15836

(UniProtKB/Swiss-Prot/P) Details

Vesicle-associated membrane protein 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Intracellular (GO:0005622)	0.994	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.994	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.994	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Trans-Golgi network membrane (GO:0032588)	0.997	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Recycling endosome (GO:0055037)	0.997	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Recycling endosome membrane (GO:0055038)	0.997	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Phagocytic vesicle membrane (GO:0030670)	0.997	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Secretory granule (GO:0030141)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Clathrin-coated vesicle (GO:0030136)	0.997	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Clathrin coated vesicle membrane (GO:0030665)	0.997	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Integral to synaptic vesicle membrane (GO:0030285)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Transport vesicle (GO:0030133)	0.997	Unknown: traceable author statement	GO	PubMed
Membrane	Neuron projection (GO:0043005)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.997	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.997	Unknown: traceable author statement	GO	PubMed
Membrane	SNARE complex (GO:0031201)	0.997	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.997	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Apical plasma membrane (GO:0016324)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.997	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.998

Q9NP94

(UniProtKB/Swiss-Prot/P) Details

Zinc transporter ZIP2

Q13520

Interaction Score

0.998

Q14210

(UniProtKB/Swiss-Prot/P) Details

Lymphocyte antigen 6D

Q13520

Interaction Score

0.998

O14735

(UniProtKB/Swiss-Prot/P) Details

CDP-diacylglycerol--inositol 3-phosphatidyltransferase

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nuclear membrane (GO:0031965)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.998	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.998	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.998	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.998	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Lysosome (GO:0005764)	0.7	Predicted: pTarget method	LOCATE	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.996	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.996	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.996	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.998

Q96FZ5

(UniProtKB/Swiss-Prot/P) Details

CKLF-like MARVEL transmembrane domain-containing protein 7

Q13520

Interaction Score

0.998

Q9UPZ6

(UniProtKB/Swiss-Prot/P) Details

Thrombospondin type-1 domain-containing protein 7A

Q13520

Interaction Score

0.998

Q9BSR8

(UniProtKB/Swiss-Prot/P) Details

Protein YIPF4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.96	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.998	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.998	Experimental: experimental	Human Proteinpedia	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.998	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.994	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.994	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.994	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.998

P15260

(UniProtKB/Swiss-Prot/P) Details

Interferon gamma receptor 1

Q13520

Interaction Score

0.998

P04921

(UniProtKB/Swiss-Prot/P) Details

Glycophorin-C

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cortical cytoskeleton (GO:0030863)	0.992	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Membrane (GO:0016020)	0.994	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.994	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.994	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.994	Experimental: experimental	Organelle	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	0.994	Unknown: traceable author statement	GO	PubMed
Membrane	Cell-cell adherens junction (GO:0005913)	0.994	Predicted: inferred from biological aspect of ancestor	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.997

Q9H2H9

(UniProtKB/Swiss-Prot/P) Details

Sodium-coupled neutral amino acid transporter 1

Q13520

Interaction Score

0.997

P30825

(UniProtKB/Swiss-Prot/P) Details

High affinity cationic amino acid transporter 1

Q13520

Interaction Score

0.997

O75379

(UniProtKB/Swiss-Prot/P) Details

Vesicle-associated membrane protein 4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Cell surface (GO:0009986)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Endomembrane system (GO:0012505)	0.972	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Trans-Golgi network membrane (GO:0032588)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Lysosome (GO:0005764)	0.972	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Clathrin coated vesicle membrane (GO:0030665)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Synaptic vesicle (GO:0008021)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Secretory-pathway	Integral to synaptic vesicle membrane (GO:0030285)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Transport vesicle (GO:0030133)	1	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.992	Experimental: experimental	eSLDB	PubMed
Membrane	SNARE complex (GO:0031201)	0.992	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.992	Unknown: traceable author statement	GO	PubMed
Cytosol	Vesicle (GO:0031982)	0.972	Experimental: experimental	eSLDB	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.997

Q03518

(UniProtKB/Swiss-Prot/P) Details

Antigen peptide transporter 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Integral to endoplasmic reticulum membrane (GO:0030176)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	TAP complex (GO:0042825)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum-Golgi intermediate compartment membrane (GO:0033116)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Lysosome (GO:0005764)	0.988	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Phagocytic vesicle membrane (GO:0030670)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	0.988	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.992	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.992	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.992	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.992	Experimental: experimental	Organelle	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.997

O00767

(UniProtKB/Swiss-Prot/P) Details

Acyl-CoA desaturase

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleolus (GO:0005730)	0.8	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.992	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.992	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.992	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.992	Predicted: pTarget method	LOCATE	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.997

O15243

(UniProtKB/Swiss-Prot/P) Details

Leptin receptor gene-related protein

Q13520

Interaction Score

0.997

Q5BJF2

(UniProtKB/Swiss-Prot/P) Details

Sigma intracellular receptor 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear membrane (GO:0031965)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear membrane (GO:0031965)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.958	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Rough endoplasmic reticulum (GO:0005791)	0.958	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Rough endoplasmic reticulum membrane (GO:0030867)	0.958	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Lysosome (GO:0005764)	0.992	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.992	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.992	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.992	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.997

Q9BQA9

(UniProtKB/Swiss-Prot/P) Details

Cytochrome b-245 chaperone 1

Q13520

Interaction Score

0.997

P54849

(UniProtKB/Swiss-Prot/P) Details

Epithelial membrane protein 1

Q13520

Interaction Score

0.997

O00155

(UniProtKB/Swiss-Prot/P) Details

Probable G-protein coupled receptor 25

Q13520

Interaction Score

0.996

Q14416

(UniProtKB/Swiss-Prot/P) Details

Metabotropic glutamate receptor 2

Q13520

Interaction Score

0.996

Q8N661

(UniProtKB/Swiss-Prot/P) Details

Lysoplasmalogenase

Q13520

Interaction Score

0.996

O95292

(UniProtKB/Swiss-Prot/P) Details

Vesicle-associated membrane protein-associated protein B/C

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.96	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.96	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	0.8	Experimental: experimental	Human Proteinpedia	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum exit site (GO:0070971)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.987	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.987	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.987	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	0.987	Predicted: PAML algorithm	PA-GOSUB	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.996

Q8IWU4

(UniProtKB/Swiss-Prot/P) Details

Zinc transporter 8

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.999	Experimental: experimental	Human Proteinpedia	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.999	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Secretory granule (GO:0030141)	0.999	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Secretory granule membrane (GO:0030667)	0.999	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Transport vesicle membrane (GO:0030658)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.987	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.987	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.987	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.987	Predicted: PAML algorithm	PA-GOSUB	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.996

Q9UHX3

(UniProtKB/Swiss-Prot/P) Details

Adhesion G protein-coupled receptor E2

Q13520

Interaction Score

0.996

P54852

(UniProtKB/Swiss-Prot/P) Details

Epithelial membrane protein 3

Q13520

Interaction Score

0.996

Q8IVJ1

(UniProtKB/Swiss-Prot/P) Details

Solute carrier family 41 member 1

Q13520

Interaction Score

0.996

Q9BRI3

(UniProtKB/Swiss-Prot/P) Details

Zinc transporter 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Late endosome (GO:0005770)	0.8	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Vacuole (GO:0005773)	0.999	Experimental: experimental	eSLDB	PubMed
Cytosol	Lysosomal membrane (GO:0005765)	0.999	Unknown: HDA	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.987	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.987	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.987	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.987	Predicted: PAML algorithm	PA-GOSUB	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.995

Q969L2

(UniProtKB/Swiss-Prot/P) Details

Protein MAL2

Q13520

Interaction Score

0.994

Q15848

(UniProtKB/Swiss-Prot/P) Details

Adiponectin

Q13520

Interaction Score

0.993

Q96MX0

(UniProtKB/Swiss-Prot/P) Details

CKLF-like MARVEL transmembrane domain-containing protein 3

Q13520

Interaction Score

0.993

O95393

(UniProtKB/Swiss-Prot/P) Details

Bone morphogenetic protein 10

Q13520

Interaction Score

0.992

Q8TDT2

(UniProtKB/Swiss-Prot/P) Details

Probable G-protein coupled receptor 152

Q13520

Interaction Score

0.992

Q6ZSM3

(UniProtKB/Swiss-Prot/P) Details

Monocarboxylate transporter 12

Q13520

Interaction Score

0.992

Q7RTY0

(UniProtKB/Swiss-Prot/P) Details

Monocarboxylate transporter 13

Q13520

Interaction Score

0.992

Q9BUN8

(UniProtKB/Swiss-Prot/P) Details

Derlin-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Signal recognition particle (GO:0048500)	0.8	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Signal recognition particle receptor complex (GO:0005785)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Cdc48p-Npl4p-Ufd1p AAA ATPase complex (GO:0034098)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Integral to endoplasmic reticulum membrane (GO:0030176)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Early endosome (GO:0005769)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Late endosome (GO:0005770)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.972	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.972	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.972	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.992

Q8TB61

(UniProtKB/Swiss-Prot/P) Details

Adenosine 3'-phospho 5'-phosphosulfate transporter 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Integral to endoplasmic reticulum membrane (GO:0030176)	0.999	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.999	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.999	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.999	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.999	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Integral to Golgi membrane (GO:0030173)	0.999	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.972	Experimental: inferred from direct assay	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.972	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.972	Unknown: non-traceable author statement	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.992

Q8IVQ6

(UniProtKB/Swiss-Prot/P) Details

Palmitoyltransferase ZDHHC21

Q13520

Interaction Score

0.992

P60059

(UniProtKB/Swiss-Prot/P) Details

Protein transport protein Sec61 subunit gamma

Q13520

Interaction Score

0.992

O95807

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 50A

Q13520

Interaction Score

0.992

Q9NP72

(UniProtKB/Swiss-Prot/P) Details

Ras-related protein Rab-18

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular (GO:0005622)	0.994	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.994	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.994	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	0.994	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.8	Experimental: experimental	Human Proteinpedia	PubMed
Secretory-pathway	Endoplasmic reticulum tubular network (GO:0071782)	0.991	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.991	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.991	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.991	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Secretory granule membrane (GO:0030667)	0.991	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.971	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.971	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.971	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Synapse (GO:0045202)	0.971	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.992

Q5QGT7

(UniProtKB/Swiss-Prot/P) Details

Receptor-transporting protein 2

Q13520

Interaction Score

0.992

Q01628

(UniProtKB/Swiss-Prot/P) Details

Interferon-induced transmembrane protein 3

Q13520

Interaction Score

0.991

Q9NV29

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 100

Q13520

Interaction Score

0.991

P20292

(UniProtKB/Swiss-Prot/P) Details

Arachidonate 5-lipoxygenase-activating protein

Q13520

Interaction Score

0.99

P27449

(UniProtKB/Swiss-Prot/P) Details

V-type proton ATPase 16 kDa proteolipid subunit

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endosome membrane (GO:0010008)	0.657	Unknown: traceable author statement	GO	PubMed
Cytosol	Vacuole (GO:0005773)	0.971	Experimental: experimental	eSLDB	PubMed
Cytosol	Vacuolar proton-transporting V-type ATPase, V0 domain (GO:0000220)	0.971	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Lysosomal membrane (GO:0005765)	0.971	Unknown: HDA	GO	PubMed
Secretory-pathway	Phagocytic vesicle membrane (GO:0030670)	0.657	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Tertiary granule membrane (GO:0070821)	0.657	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.971	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.971	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.971	Unknown: traceable author statement	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.971	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.971	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.989

P18031

(UniProtKB/Swiss-Prot/P) Details

Tyrosine-protein phosphatase non-receptor type 1

Q13520

Interaction Score

0.989

P78329

(UniProtKB/Swiss-Prot/P) Details

Phylloquinone omega-hydroxylase CYP4F2

Q13520

Interaction Score

0.989

Q16617

(UniProtKB/Swiss-Prot/P) Details

Protein NKG7

Q13520

Interaction Score

0.989

Q13190

(UniProtKB/Swiss-Prot/P) Details

Syntaxin-5

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum-Golgi intermediate compartment membrane (GO:0033116)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Secretory-pathway	ER to Golgi transport vesicle membrane (GO:0012507)	1	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.958	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.958	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	SNARE complex (GO:0031201)	0.958	Unknown: traceable author statement	GO	PubMed
Cytosol	Vesicle (GO:0031982)	0.86	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.988

Q15041

(UniProtKB/Swiss-Prot/P) Details

ADP-ribosylation factor-like protein 6-interacting protein 1

Q13520

Interaction Score

0.988

P78382

(UniProtKB/Swiss-Prot/P) Details

CMP-sialic acid transporter

Q13520

Interaction Score

0.988

A2RU14

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 218

Q13520

Interaction Score

0.988

Q8TDV0

(UniProtKB/Swiss-Prot/P) Details

Probable G-protein coupled receptor 151

Q13520

Interaction Score

0.988

Q92504

(UniProtKB/Swiss-Prot/P) Details

Zinc transporter SLC39A7

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.994	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.994	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.994	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.994	Predicted: pTarget method	LOCATE	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.956	Unknown: traceable author statement	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.956	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.956	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.956	Predicted: PAML algorithm	PA-GOSUB	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.988

Q969E2

(UniProtKB/Swiss-Prot/P) Details

Secretory carrier-associated membrane protein 4

Q13520

Interaction Score

0.988

Q9NZG7

(UniProtKB/Swiss-Prot/P) Details

Ninjurin-2

Q13520

Interaction Score

0.987

O95562

(UniProtKB/Swiss-Prot/P) Details

Vesicle transport protein SFT2B

Q13520

Interaction Score

0.986

Q9NS71

(UniProtKB/Swiss-Prot/P) Details

Gastrokine-1

Q13520

Interaction Score

0.984

O14925

(UniProtKB/Swiss-Prot/P) Details

Mitochondrial import inner membrane translocase subunit Tim23

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: pTarget method	LOCATE	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	Organelle	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial intermembrane space (GO:0005758)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrial inner membrane (GO:0005743)	1	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrial inner membrane presequence translocase complex (GO:0005744)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Integral to mitochondrial inner membrane (GO:0031305)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.96	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: experimental	Organelle	PubMed
Cytosol	Organelle inner membrane (GO:0019866)	0.8	Experimental: experimental	Organelle	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.984

P09601

(UniProtKB/Swiss-Prot/P) Details

Heme oxygenase 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.86	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.79	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	0.79	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.999	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.999	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.999	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.999	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.999	Unknown: unspecified method	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.86	Unknown: traceable author statement	GO	PubMed
Membrane	Membrane (GO:0016020)	0.931	Unknown: traceable author statement	GO	PubMed
Membrane	Membrane (GO:0016020)	0.931	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.931	Unknown: unspecified method	The Human Protein Atlas	PubMed
Membrane	Caveola (GO:0005901)	0.931	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.984

Q9BV81

(UniProtKB/Swiss-Prot/P) Details

ER membrane protein complex subunit 6

Q13520

Interaction Score

0.984

Q9H0R3

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 222

Q13520

Interaction Score

0.984

Q9NWF4

(UniProtKB/Swiss-Prot/P) Details

Solute carrier family 52, riboflavin transporter, member 1

Q13520

Interaction Score

0.984

Q8WV19

(UniProtKB/Swiss-Prot/P) Details

Vesicle transport protein SFT2A

Q13520

Interaction Score

0.984

P47884

(UniProtKB/Swiss-Prot/P) Details

Olfactory receptor 1D4

Q13520

Interaction Score

0.983

Q9NUM3

(UniProtKB/Swiss-Prot/P) Details

Zinc transporter ZIP9

Q13520

Interaction Score

0.983

Q96IW7

(UniProtKB/Swiss-Prot/P) Details

Vesicle-trafficking protein SEC22a

Q13520

Interaction Score

0.982

Q8NET1

(UniProtKB/Swiss-Prot/P) Details

Beta-defensin 108B

Q13520

Interaction Score

0.982

Q8N5I4

(UniProtKB/Swiss-Prot/P) Details

Dehydrogenase/reductase SDR family member on chromosome X

Q13520

Interaction Score

0.982

Q96JW4

(UniProtKB/Swiss-Prot/P) Details

Solute carrier family 41 member 2

Q13520

Interaction Score

0.981

Q9NRZ7

(UniProtKB/Swiss-Prot/P) Details

1-acyl-sn-glycerol-3-phosphate acyltransferase gamma

Q13520

Interaction Score

0.979

Q6UX34

(UniProtKB/Swiss-Prot/P) Details

Protein SNORC

Q13520

Interaction Score

0.978

Q6ZPD8

(UniProtKB/Swiss-Prot/P) Details

Diacylglycerol O-acyltransferase 2-like protein 6

Q13520

Interaction Score

0.976

O76024

(UniProtKB/Swiss-Prot/P) Details

Wolframin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Proteasome complex (GO:0000502)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.994	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.994	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endoplasmic reticulum lumen (GO:0005788)	0.994	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.994	Unknown: non-traceable author statement	GO	PubMed
Secretory-pathway	Integral to endoplasmic reticulum membrane (GO:0030176)	0.994	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Integral to synaptic vesicle membrane (GO:0030285)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendrite (GO:0030425)	0.91	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.91	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.976

Q96HH6

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 19

Q13520

Interaction Score

0.976

Q8NHS1

(UniProtKB/Swiss-Prot/P) Details

Claudin domain-containing protein 2

Q13520

Interaction Score

0.976

Q92982

(UniProtKB/Swiss-Prot/P) Details

Ninjurin-1

Q13520

Interaction Score

0.976

Q7Z5S9

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 144

Q13520

Interaction Score

0.976

Q9BXJ8

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 120A

Q13520

Interaction Score

0.976

Q6ICL7

(UniProtKB/Swiss-Prot/P) Details

Solute carrier family 35 member E4

Q13520

Interaction Score

0.974

Q8N138

(UniProtKB/Swiss-Prot/P) Details

ORM1-like protein 3

Q13520

Interaction Score

0.974

O60725

(UniProtKB/Swiss-Prot/P) Details

Protein-S-isoprenylcysteine O-methyltransferase

Q13520

Interaction Score

0.974

O43169

(UniProtKB/Swiss-Prot/P) Details

Cytochrome b5 type B

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.958	Experimental: experimental	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.958	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrial outer membrane (GO:0005741)	0.958	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.902	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.902	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.902	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.974

Q9HDC5

(UniProtKB/Swiss-Prot/P) Details

Junctophilin-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Junctional membrane complex (GO:0030314)	0.931	Unknown: non-traceable author statement	GO	PubMed
Cytosol	Junctional sarcoplasmic reticulum membrane (GO:0014701)	0.931	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.992	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.94	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Z disc (GO:0030018)	0.931	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.931	Experimental: experimental	eSLDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.902	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.902	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.972

P34810

(UniProtKB/Swiss-Prot/P) Details

Macrosialin

Q13520

Interaction Score

0.971

O14798

(UniProtKB/Swiss-Prot/P) Details

Tumor necrosis factor receptor superfamily member 10C

Q13520

Interaction Score

0.971

Q8IY26

(UniProtKB/Swiss-Prot/P) Details

Phospholipid phosphatase 6

Q13520

Interaction Score

0.97

P02652

(UniProtKB/Swiss-Prot/P) Details

Apolipoprotein A-II

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.902	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.902	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	0.902	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum lumen (GO:0005788)	0.902	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Early endosome (GO:0005769)	0.902	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	1	Unknown: non-traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	1	Predicted: pTarget method	LOCATE	PubMed
Extracellular	Extracellular region (GO:0005576)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Blood microparticle (GO:0072562)	1	Unknown: HDA	GO	PubMed
Extracellular	Very-low-density lipoprotein particle (GO:0034361)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Chylomicron (GO:0042627)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	High-density lipoprotein particle (GO:0034364)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Spherical high-density lipoprotein particle (GO:0034366)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Membrane (GO:0016020)	0.8	Experimental: experimental	MatrixDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.902	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.968

P11684

(UniProtKB/Swiss-Prot/P) Details

Uteroglobin

Q13520

Interaction Score

0.965

P81534

(UniProtKB/Swiss-Prot/P) Details

Beta-defensin 103

Q13520

Interaction Score

0.964

Q9BWQ6

(UniProtKB/Swiss-Prot/P) Details

Protein YIPF2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Mitochondrion	Mitochondrion (GO:0005739)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: experimental	Human Proteinpedia	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi trans cisterna (GO:0000138)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi medial cisterna (GO:0005797)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Trans-Golgi network (GO:0005802)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Late endosome membrane (GO:0031902)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Transport vesicle (GO:0030133)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.86	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.86	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.964

Q9Y548

(UniProtKB/Swiss-Prot/P) Details

Protein YIPF1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: experimental	Human Proteinpedia	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: experimental	Human Proteinpedia	PubMed
Secretory-pathway	Golgi trans cisterna (GO:0000138)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi medial cisterna (GO:0005797)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Trans-Golgi network (GO:0005802)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Late endosome membrane (GO:0031902)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Transport vesicle (GO:0030133)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.86	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.86	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.964

Q9P0S3

(UniProtKB/Swiss-Prot/P) Details

ORM1-like protein 1

Q13520

Interaction Score

0.964

Q53FV1

(UniProtKB/Swiss-Prot/P) Details

ORM1-like protein 2

Q13520

Interaction Score

0.964

P37268

(UniProtKB/Swiss-Prot/P) Details

Squalene synthase

Q13520

Interaction Score

0.964

Q6ZVE7

(UniProtKB/Swiss-Prot/P) Details

Vesicle transport protein GOT1A

Q13520

Interaction Score

0.964

Q8WWP7

(UniProtKB/Swiss-Prot/P) Details

GTPase IMAP family member 1

Q13520

Interaction Score

0.964

Q07326

(UniProtKB/Swiss-Prot/P) Details

Phosphatidylinositol-glycan biosynthesis class F protein

Q13520

Interaction Score

0.964

Q8N511

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 199

Q13520

Interaction Score

0.964

Q9P0N8

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase MARCH2

Q13520

Interaction Score

0.964

Q8N0U8

(UniProtKB/Swiss-Prot/P) Details

Vitamin K epoxide reductase complex subunit 1-like protein 1

Q13520

Interaction Score

0.964

Q9H2C2

(UniProtKB/Swiss-Prot/P) Details

Protein ARV1

Q13520

Interaction Score

0.963

Q9Y6G1

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 14A

Q13520

Interaction Score

0.963

Q8WVV5

(UniProtKB/Swiss-Prot/P) Details

Butyrophilin subfamily 2 member A2

Q13520

Interaction Score

0.962

O14653

(UniProtKB/Swiss-Prot/P) Details

Golgi SNAP receptor complex member 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.79	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	0.79	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Secretory-pathway	Endoplasmic reticulum-Golgi intermediate compartment membrane (GO:0033116)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Late endosome membrane (GO:0031902)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Secretory-pathway	ER to Golgi transport vesicle membrane (GO:0012507)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.853	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.853	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	SNARE complex (GO:0031201)	0.853	Predicted: inferred from sequence or structural similarity	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.962

Q9Y6D0

(UniProtKB/Swiss-Prot/P) Details

Selenoprotein K

Q13520

Interaction Score

0.962

Q6N075

(UniProtKB/Swiss-Prot/P) Details

Molybdate-anion transporter

Q13520

Interaction Score

0.962

O60831

(UniProtKB/Swiss-Prot/P) Details

PRA1 family protein 2

Q13520

Interaction Score

0.961

Q9NX47

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase MARCH5

Q13520

Interaction Score

0.961

P01350

(UniProtKB/Swiss-Prot/P) Details

Gastrin

Q13520

Interaction Score

0.96

P09466

(UniProtKB/Swiss-Prot/P) Details

Glycodelin

Q13520

Interaction Score

0.96

O95406

(UniProtKB/Swiss-Prot/P) Details

Protein cornichon homolog 1

Q13520

Interaction Score

0.959

Q6UX98

(UniProtKB/Swiss-Prot/P) Details

Probable palmitoyltransferase ZDHHC24

Q13520

Interaction Score

0.959

Q96GQ5

(UniProtKB/Swiss-Prot/P) Details

RUS1 family protein C16orf58

Q13520

Interaction Score

0.957

Q8IXM6

(UniProtKB/Swiss-Prot/P) Details

Nurim

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Endomembrane system (GO:0012505)	0.8	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nuclear membrane (GO:0031965)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear membrane (GO:0031965)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear inner membrane (GO:0005637)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nuclear envelope (GO:0005635)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.853	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.853	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.853	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.951

Q7Z2K6

(UniProtKB/Swiss-Prot/P) Details

Endoplasmic reticulum metallopeptidase 1

Q13520

Interaction Score

0.949

P78383

(UniProtKB/Swiss-Prot/P) Details

Solute carrier family 35 member B1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.86	Unknown: traceable author statement	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.86	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Integral to endoplasmic reticulum membrane (GO:0030176)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Integral to Golgi membrane (GO:0030173)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.8	Experimental: experimental	eSLDB	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.949

Q96BZ9

(UniProtKB/Swiss-Prot/P) Details

TBC1 domain family member 20

Q13520

Interaction Score

0.948

Q13113

(UniProtKB/Swiss-Prot/P) Details

PDZK1-interacting protein 1

Q13520

Interaction Score

0.948

Q9NW97

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 51

Q13520

Interaction Score

0.948

Q9BU79

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 243

Q13520

Interaction Score

0.948

Q9NS69

(UniProtKB/Swiss-Prot/P) Details

Mitochondrial import receptor subunit TOM22 homolog

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	Organelle	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial outer membrane (GO:0005741)	1	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrial outer membrane translocase complex (GO:0005742)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Integral to mitochondrial outer membrane (GO:0031307)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.86	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.86	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.948

Q96NB2

(UniProtKB/Swiss-Prot/P) Details

Sideroflexin-2

Q13520

Interaction Score

0.948

Q96F15

(UniProtKB/Swiss-Prot/P) Details

GTPase IMAP family member 5

Q13520

Interaction Score

0.948

Q9H2L4

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 60

Q13520

Interaction Score

0.948

Q8TD22

(UniProtKB/Swiss-Prot/P) Details

Sideroflexin-5

Q13520

Interaction Score

0.946

Q96EC8

(UniProtKB/Swiss-Prot/P) Details

Protein YIPF6

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: experimental	Human Proteinpedia	PubMed
Secretory-pathway	Golgi trans cisterna (GO:0000138)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi medial cisterna (GO:0005797)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Cis-Golgi network (GO:0005801)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Trans-Golgi network (GO:0005802)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	ER to Golgi transport vesicle (GO:0030134)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.79	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.79	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.946

O75396

(UniProtKB/Swiss-Prot/P) Details

Vesicle-trafficking protein SEC22b

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Endomembrane system (GO:0012505)	0.96	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	0.8	Experimental: experimental	Human Proteinpedia	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum-Golgi intermediate compartment (GO:0005793)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum-Golgi intermediate compartment membrane (GO:0033116)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Phagocytic vesicle membrane (GO:0030670)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Melanosome (GO:0042470)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	ER to Golgi transport vesicle membrane (GO:0012507)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Synaptic vesicle (GO:0008021)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Transport vesicle (GO:0030133)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.96	Experimental: experimental	Human Proteinpedia	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.79	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	SNARE complex (GO:0031201)	0.79	Predicted: inferred from biological aspect of ancestor	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.946

Q9NTJ5

(UniProtKB/Swiss-Prot/P) Details

Phosphatidylinositide phosphatase SAC1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: experimental	Human Proteinpedia	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Integral to endoplasmic reticulum membrane (GO:0030176)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: experimental	Human Proteinpedia	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	1	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.79	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex (GO:0032281)	0.79	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q13520

Interaction Score

0.946

Q9NZ43

(UniProtKB/Swiss-Prot/P) Details

Vesicle transport protein USE1

Q13520

Interaction Score

0.946

Q3ZAQ7

(UniProtKB/Swiss-Prot/P) Details

Vacuolar ATPase assembly integral membrane protein VMA21

Q13520

Interaction Score

0.946

Q96CP7

(UniProtKB/Swiss-Prot/P) Details

Calfacilitin

Q13520

Interaction Score

0.946

Q96IV6

(UniProtKB/Swiss-Prot/P) Details

Fatty acid hydroxylase domain-containing protein 2

Q13520

Interaction Score

0.945

Q14849

(UniProtKB/Swiss-Prot/P) Details

StAR-related lipid transfer protein 3

Q13520

Interaction Score

0.945

Q6ZNB7

(UniProtKB/Swiss-Prot/P) Details

Alkylglycerol monooxygenase

Q13520

Interaction Score

0.945

Q7L5A8

(UniProtKB/Swiss-Prot/P) Details

Fatty acid 2-hydroxylase

Q13520

Interaction Score

0.945

Q5TGU0

(UniProtKB/Swiss-Prot/P) Details

Translocator protein 2

Q13520

Interaction Score

0.945

Q8N2K1

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin-conjugating enzyme E2 J2

Q13520

Interaction Score

0.944

Q8NBI2

(UniProtKB/Swiss-Prot/P) Details

Cytochrome b ascorbate-dependent protein 3

Q13520

Interaction Score

0.943

Q8N5M9

(UniProtKB/Swiss-Prot/P) Details

Protein jagunal homolog 1

Q13520

Interaction Score

0.942

Q71RG4

(UniProtKB/Swiss-Prot/P) Details

Transmembrane and ubiquitin-like domain-containing protein 2

Q13520

Interaction Score

0.941

P14060

(UniProtKB/Swiss-Prot/P) Details

3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1

Q13520

Interaction Score

0.941

Q8N6R1

(UniProtKB/Swiss-Prot/P) Details

Stress-associated endoplasmic reticulum protein 2

Q13520

Interaction Score

0.941

P02808

(UniProtKB/Swiss-Prot/P) Details

Statherin

Q13520

Interaction Score

0.939

Q9Y320

(UniProtKB/Swiss-Prot/P) Details

Thioredoxin-related transmembrane protein 2

Q13520

Interaction Score

0.939

Q68G75

(UniProtKB/Swiss-Prot/P) Details

LEM domain-containing protein 1

Q13520

Interaction Score

0.939

Q96AA3

(UniProtKB/Swiss-Prot/P) Details

Protein RFT1 homolog

Q13520

Interaction Score

0.939

Q8N8Q1

(UniProtKB/Swiss-Prot/P) Details

Cytochrome b561 domain-containing protein 1

Q13520

Interaction Score

0.93

Q96NL1

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 74

Q13520

Interaction Score

0.93

Q9NRX6

(UniProtKB/Swiss-Prot/P) Details

Protein kish-B

Q13520

Interaction Score

0.93

P48449

(UniProtKB/Swiss-Prot/P) Details

Lanosterol synthase

Q13520

Interaction Score

0.927

A0A1P0AYU5

(UniProtKB/TrEmbl/P) Details

Sideroflexin

Q13520

Interaction Score

0.927

Q96HA9

(UniProtKB/Swiss-Prot/P) Details

Peroxisomal membrane protein 11C

Q13520

Interaction Score

0.927

P57105

(UniProtKB/Swiss-Prot/P) Details

Synaptojanin-2-binding protein

Q13520

Interaction Score

0.924

Q969S0

(UniProtKB/Swiss-Prot/P) Details

UDP-xylose and UDP-N-acetylglucosamine transporter

Q13520

Interaction Score

0.923

Q9NV12

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 140

Q13520

Interaction Score

0.923

O95870

(UniProtKB/Swiss-Prot/P) Details

Protein ABHD16A

Q13520

Interaction Score

0.923

Q69YG0

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 42

Q13520

Interaction Score

0.923

Q8WY98

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 234

Q13520

Interaction Score

0.923

Q9H9B4

(UniProtKB/Swiss-Prot/P) Details

Sideroflexin-1

Q13520

Interaction Score

0.923

Q5SWH9

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 69

Q13520

Interaction Score

0.923

A0PK00

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 120B

Q13520

Interaction Score

0.923

Q5T1Q4

(UniProtKB/Swiss-Prot/P) Details

Solute carrier family 35 member F1

Q13520

Interaction Score

0.923

Q5JRM2

(UniProtKB/Swiss-Prot/P) Details

Uncharacterized protein CXorf66

Q13520

Interaction Score

0.923

Q5J8X5

(UniProtKB/Swiss-Prot/P) Details

Membrane-spanning 4-domains subfamily A member 13

Q13520

Interaction Score

0.923

Q4LDR2

(UniProtKB/Swiss-Prot/P) Details

Cortexin-3

Q13520

Interaction Score

0.923

Q8NBD8

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 229B

Q13520

Interaction Score

0.905

O43451

(UniProtKB/Swiss-Prot/P) Details

Maltase-glucoamylase, intestinal

Q13520

Interaction Score

0.878

Q99674

(UniProtKB/Swiss-Prot/P) Details

Cell growth regulator with EF hand domain protein 1

Q13520

Interaction Score

0.852

Q6UWT4

(UniProtKB/Swiss-Prot/P) Details

Uncharacterized protein C5orf46

Q13520

Interaction Score

0.823

B2RUZ4

(UniProtKB/Swiss-Prot/P) Details

Small integral membrane protein 1

Q13520

Interaction Score

0.813

Q969S6

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 203

Q13520

Interaction Score

0.801

O75106

(UniProtKB/Swiss-Prot/P) Details

Retina-specific copper amine oxidase

Q13520

Interaction Score

0.797

Q6IBD0

(UniProtKB/TrEmbl/P) Details

CD52 antigen

Q13520

Interaction Score

0.787

I3L0A0

(UniProtKB/TrEmbl/P) Details

HCG2044781

Q13520

Interaction Score

0.785

Q96LL9

(UniProtKB/Swiss-Prot/P) Details

DnaJ homolog subfamily C member 30

Q13520

Interaction Score

0.77

Q5BVD1

(UniProtKB/Swiss-Prot/P) Details

TPA-induced transmembrane protein

Q13520

Interaction Score

0.748

O00124

(UniProtKB/Swiss-Prot/P) Details

UBX domain-containing protein 8

Q13520

Interaction Score

0.748

Q5RI15

(UniProtKB/Swiss-Prot/P) Details

Cytochrome c oxidase assembly protein COX20, mitochondrial

Q13520

Interaction Score

0.748

A6NDP7

(UniProtKB/Swiss-Prot/P) Details

Myeloid-associated differentiation marker-like protein 2

Q13520

Interaction Score

0.748

E9PQX1

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 262

Q13520

Interaction Score

0.741

Q6NT55

(UniProtKB/Swiss-Prot/P) Details

Cytochrome P450 4F22

Q13520

Interaction Score

0.697

Q9NUU6

(UniProtKB/Swiss-Prot/P) Details

Inactive ubiquitin thioesterase FAM105A

Q13520

Interaction Score

0.697

Q9BWH2

(UniProtKB/Swiss-Prot/P) Details

FUN14 domain-containing protein 2

Q13520

Interaction Score

0.697

A0A0C4DFN3

(UniProtKB/TrEmbl/P) Details

Monoglyceride lipase

Q13520

Interaction Score

0.64

Q96B49

(UniProtKB/Swiss-Prot/P) Details

Mitochondrial import receptor subunit TOM6 homolog

Q13520

Interaction Score

0.299

A0A1B0GTW0

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein

Q13520

Interaction Score

0.21

Q59EV6

(UniProtKB/TrEmbl/P) Details

Carboxypeptidase

Q13520

Interaction Score

0.21

A5D903

(UniProtKB/TrEmbl/P) Details

PRB1 protein

Q13520

Interaction Score

Q8WUN7

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin domain-containing protein 2

Q13520

Interaction Score

Q96SQ5

(UniProtKB/Swiss-Prot/P) Details

Zinc finger protein 587

Q13520

Interaction Score

Q6ZUI0

(UniProtKB/Swiss-Prot/P) Details

Tumor protein p63-regulated gene 1 protein

Q13520

Interaction Score

C9JKN6

(UniProtKB/TrEmbl/P) Details

Thrombospondin type-1 domain-containing protein 7B

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Q13520

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

Q13520

P02786

Transferrin receptor protein 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q13520

P50281

Matrix metalloproteinase-14

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q13520

P11215

Integrin alpha-M

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q13520

P29972

Aquaporin-1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q13520

P52803

Ephrin-A5

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q13520

Q9Y5Q5

Atrial natriuretic peptide-converting enzyme

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q13520

Q13277

Syntaxin-3

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q13520

P61266

Syntaxin-1B

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q13520

P07204

Thrombomodulin

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q13520

O95183

Vesicle-associated membrane protein 5

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q13520

Q7Z6L0

Proline-rich transmembrane protein 2

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q13520

Q8TAC9

Secretory carrier-associated membrane protein 5

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q13520