O95674

Phosphatidate cytidylyltransferase 2 // UniProt Profile

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Species	H. sapiens
Number of Interactions	32 / 33
Average Interaction Score	0.91

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.992	Experimental: experimental	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.992	Predicted: pTarget method	LOCATE	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.992	Experimental: experimental	Organelle	PubMed
Mitochondrion	Mitochondrial inner membrane (GO:0005743)	0.992	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.94	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.902	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.902	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Organelle inner membrane (GO:0019866)	0.96	Experimental: experimental	Organelle	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

O95674

Interaction Score

Q13286

(UniProtKB/Swiss-Prot/P) Details

Battenin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.86	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.86	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	0.8	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Integral to endoplasmic reticulum membrane (GO:0030176)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi stack (GO:0005795)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Trans-Golgi network (GO:0005802)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Early endosome (GO:0005769)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Late endosome (GO:0005770)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Autophagic vacuole (GO:0005776)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Lysosome (GO:0005764)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Lysosome (GO:0005764)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Lysosome (GO:0005764)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Lysosome (GO:0005764)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Lysosomal membrane (GO:0005765)	1	Unknown: HDA	GO	PubMed
Secretory-pathway	Synaptic vesicle (GO:0008021)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Neuron projection (GO:0043005)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Membrane raft (GO:0045121)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Caveola (GO:0005901)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O95674

Interaction Score

Q99816

(UniProtKB/Swiss-Prot/P) Details

Tumor susceptibility gene 101 protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Flemming body (GO:0090543)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleolus (GO:0005730)	0.992	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endosome (GO:0005768)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Early endosome (GO:0005769)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Late endosome membrane (GO:0031902)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Early endosome membrane (GO:0031901)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Late endosome (GO:0005770)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Secretory-pathway	Multivesicular body (GO:0005771)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endosome membrane (GO:0010008)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	ESCRT I complex (GO:0000813)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.994	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.994	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.994	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

O95674

Interaction Score

O75503

(UniProtKB/Swiss-Prot/P) Details

Ceroid-lipofuscinosis neuronal protein 5

O95674

Interaction Score

0.999

Q8IWL3

(UniProtKB/Swiss-Prot/P) Details

Iron-sulfur cluster co-chaperone protein HscB, mitochondrial

O95674

Interaction Score

0.998

Q9Y282

(UniProtKB/Swiss-Prot/P) Details

Endoplasmic reticulum-Golgi intermediate compartment protein 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.986	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.986	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endoplasmic reticulum-Golgi intermediate compartment membrane (GO:0033116)	0.986	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.986	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.986	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.853	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.853	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.853	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

O95674

Interaction Score

0.998

O43889

(UniProtKB/Swiss-Prot/P) Details

Cyclic AMP-responsive element-binding protein 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.988	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	0.988	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.971	Unknown: inferred by curator	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.971	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	0.971	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.971	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.902	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.902	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.3	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O95674

Interaction Score

0.998

Q16740

(UniProtKB/Swiss-Prot/P) Details

ATP-dependent Clp protease proteolytic subunit, mitochondrial

O95674

Interaction Score

0.997

Q8TED1

(UniProtKB/Swiss-Prot/P) Details

Probable glutathione peroxidase 8

O95674

Interaction Score

0.996

O95859

(UniProtKB/Swiss-Prot/P) Details

Tetraspanin-12

O95674

Interaction Score

0.996

Q6NUS6

(UniProtKB/Swiss-Prot/P) Details

Tectonic-3

O95674

Interaction Score

0.995

Q96MG2

(UniProtKB/Swiss-Prot/P) Details

Junctional sarcoplasmic reticulum protein 1

O95674

Interaction Score

0.994

Q9H9V4

(UniProtKB/Swiss-Prot/P) Details

RING finger protein 122

O95674

Interaction Score

0.985

P02545

(UniProtKB/Swiss-Prot/P) Details

Prelamin-A/C

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Endomembrane system (GO:0012505)	0.998	Experimental: experimental	Organelle	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Unknown: HDA	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Lamin filament (GO:0005638)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nuclear membrane (GO:0031965)	1	Unknown: HDA	GO	PubMed
Nucleus	Nuclear envelope (GO:0005635)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.998	Experimental: experimental	Organelle	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.8	Experimental: experimental	MatrixDB	PubMed
Cytosol	Organelle inner membrane (GO:0019866)	0.998	Experimental: experimental	Organelle	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O95674

Interaction Score

0.983

P31937

(UniProtKB/Swiss-Prot/P) Details

3-hydroxyisobutyrate dehydrogenase, mitochondrial

O95674

Interaction Score

0.981

Q7Z7G2

(UniProtKB/Swiss-Prot/P) Details

Complexin-4

O95674

Interaction Score

0.974

Q13651

(UniProtKB/Swiss-Prot/P) Details

Interleukin-10 receptor subunit alpha

O95674

Interaction Score

0.974

Q9H2H9

(UniProtKB/Swiss-Prot/P) Details

Sodium-coupled neutral amino acid transporter 1

O95674

Interaction Score

0.962

Q8IV31

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 139

O95674

Interaction Score

0.959

Q8TDT2

(UniProtKB/Swiss-Prot/P) Details

Probable G-protein coupled receptor 152

O95674

Interaction Score

0.943

Q9HBL7

(UniProtKB/Swiss-Prot/P) Details

Plasminogen receptor

O95674

Interaction Score

0.941

Q8TAF8

(UniProtKB/Swiss-Prot/P) Details

LHFPL tetraspan subfamily member 5 protein

O95674

Interaction Score

0.936

Q5JX71

(UniProtKB/Swiss-Prot/P) Details

Protein FAM209A

O95674

Interaction Score

0.932

Q9HB07

(UniProtKB/Swiss-Prot/P) Details

UPF0160 protein MYG1, mitochondrial

O95674

Interaction Score

0.926

Q96B21

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 45B

O95674

Interaction Score

0.897

Q8WWF3

(UniProtKB/Swiss-Prot/P) Details

Serine-rich single-pass membrane protein 1

O95674

Interaction Score

0.882

A0A024QZB8

(UniProtKB/TrEmbl/P) Details

Battenin

O95674

Interaction Score

0.882

Q2TA70

(UniProtKB/TrEmbl/P) Details

Battenin

O95674

Interaction Score

0.867

B4DFF3

(UniProtKB/TrEmbl/P) Details

Battenin

O95674

Interaction Score

0.819

Q14684

(UniProtKB/Swiss-Prot/P) Details

Ribosomal RNA processing protein 1 homolog B

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Preribosome, large subunit precursor (GO:0030687)	0.853	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Preribosome, small subunit precursor (GO:0030688)	0.853	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.853	Unknown: HDA	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Unknown: HDA	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Granular component (GO:0001652)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Euchromatin (GO:0000791)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Heterochromatin (GO:0000792)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

O95674

Interaction Score

0.672

Q5TCI8

(UniProtKB/TrEmbl/P) Details

Prelamin-A/C

O95674

Interaction Score

0.64

B4DMY6

(UniProtKB/TrEmbl/P) Details

Battenin

O95674

Interaction Score

A8MZ59

(UniProtKB/Swiss-Prot/P) Details

Leucine-twenty homeobox

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O95674

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

O95674

Q13286

Battenin

Localizations:

Interaction Source Database:

Interaction Source Publication:

O95674

Q99816

Tumor susceptibility gene 101 protein

Localizations:

Interaction Source Database:

Interaction Source Publication:

O95674

O75503

Ceroid-lipofuscinosis neuronal protein 5

Localizations:

Interaction Source Database:

Interaction Source Publication:

O95674

Q8IWL3

Iron-sulfur cluster co-chaperone protein HscB, mitochondrial

Localizations:

Interaction Source Database:

Interaction Source Publication:

O95674

Q9Y282

Endoplasmic reticulum-Golgi intermediate compartment protein 3

Localizations:

Interaction Source Database:

Interaction Source Publication:

O95674

O43889

Cyclic AMP-responsive element-binding protein 3

Localizations:

Interaction Source Database:

Interaction Source Publication:

O95674

Q16740

ATP-dependent Clp protease proteolytic subunit, mitochondrial

Localizations:

Interaction Source Database:

Interaction Source Publication:

O95674

Q8TED1

Probable glutathione peroxidase 8

Localizations:

Interaction Source Database:

Interaction Source Publication:

O95674

O95859

Tetraspanin-12

Localizations:

Interaction Source Database:

Interaction Source Publication:

O95674

Q6NUS6

Tectonic-3

Localizations:

Interaction Source Database:

Interaction Source Publication:

O95674

Q96MG2

Junctional sarcoplasmic reticulum protein 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

O95674

Q9H9V4

RING finger protein 122

Localizations:

Interaction Source Database:

Interaction Source Publication:

O95674