Q16740

ATP-dependent Clp protease proteolytic subunit, mitochondrial // UniProt Profile

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Species	H. sapiens
Number of Interactions	111 / 120
Average Interaction Score	0.812

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Endopeptidase Clp complex (GO:0009368)	0.8	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial matrix (GO:0005759)	1	Experimental: inferred from direct assay	GO	PubMed

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Interactions

All Details

Q16740

Interaction Score

O76031

(UniProtKB/Swiss-Prot/P) Details

ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Endopeptidase Clp complex (GO:0009368)	0.96	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.96	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	Organelle	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial matrix (GO:0005759)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrial nucleoid (GO:0042645)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrial endopeptidase Clp complex (GO:0009841)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrial inner membrane (GO:0005743)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, DIP, IntAct

Interaction Source Publication:

PubMed

, PubMed

Q16740

Interaction Score

Q9Y697

(UniProtKB/Swiss-Prot/P) Details

Cysteine desulfurase, mitochondrial

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: experimental	Organelle	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	Human Proteinpedia	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	Organelle	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrial matrix (GO:0005759)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q16740

Interaction Score

Q12931

(UniProtKB/Swiss-Prot/P) Details

Heat shock protein 75 kDa, mitochondrial

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial matrix (GO:0005759)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrial intermembrane space (GO:0005758)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Mitochondrion	Mitochondrial inner membrane (GO:0005743)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.94	Experimental: experimental	Human Proteinpedia	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed

Interaction Source Database:

DIP

Interaction Source Publication:

PubMed

Q16740

Interaction Score

P10809

(UniProtKB/Swiss-Prot/P) Details

60 kDa heat shock protein, mitochondrial

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Coated pit (GO:0005905)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: SVM decision tree	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	Organelle	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial matrix (GO:0005759)	1	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrial inner membrane (GO:0005743)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Cyclin-dependent protein kinase activating kinase holoenzyme complex (GO:0019907)	0.96	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Early endosome (GO:0005769)	0.988	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Secretory granule (GO:0030141)	0.988	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Coated vesicle (GO:0030135)	0.988	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.992	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.992	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.992	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.999	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	0.999	Experimental: experimental	MatrixDB	PubMed
Membrane	Lipopolysaccharide receptor complex (GO:0046696)	0.999	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q16740

Interaction Score

P52815

(UniProtKB/Swiss-Prot/P) Details

39S ribosomal protein L12, mitochondrial

Q16740

Interaction Score

O00483

(UniProtKB/Swiss-Prot/P) Details

Cytochrome c oxidase subunit NDUFA4

Q16740

Interaction Score

P11310

(UniProtKB/Swiss-Prot/P) Details

Medium-chain specific acyl-CoA dehydrogenase, mitochondrial

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	Human Proteinpedia	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: pTarget method	LOCATE	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	Organelle	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial matrix (GO:0005759)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrial membrane (GO:0031966)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.86	Unknown: HDA	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	0.86	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Peroxisome (GO:0005777)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Axon (GO:0030424)	0.8	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q16740

Interaction Score

Q9UHN1

(UniProtKB/Swiss-Prot/P) Details

DNA polymerase subunit gamma-2, mitochondrial

Q16740

Interaction Score

Q99643

(UniProtKB/Swiss-Prot/P) Details

Succinate dehydrogenase cytochrome b560 subunit, mitochondrial

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: pTarget method	LOCATE	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	Organelle	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrial inner membrane (GO:0005743)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Mitochondrion	Mitochondrial respiratory chain complex II (GO:0005749)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Lysosome (GO:0005764)	0.7	Predicted: pTarget method	LOCATE	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Respiratory chain complex II (GO:0045273)	0.853	Unknown: traceable author statement	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.853	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.853	Unknown: traceable author statement	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q16740

Interaction Score

O75880

(UniProtKB/Swiss-Prot/P) Details

Protein SCO1 homolog, mitochondrial

Q16740

Interaction Score

Q04837

(UniProtKB/Swiss-Prot/P) Details

Single-stranded DNA-binding protein, mitochondrial

Q16740

Interaction Score

Q00059

(UniProtKB/Swiss-Prot/P) Details

Transcription factor A, mitochondrial

Q16740

Interaction Score

Q9UGM6

(UniProtKB/Swiss-Prot/P) Details

Tryptophan--tRNA ligase, mitochondrial

Q16740

Interaction Score

P49448

(UniProtKB/Swiss-Prot/P) Details

Glutamate dehydrogenase 2, mitochondrial

Q16740

Interaction Score

P45954

(UniProtKB/Swiss-Prot/P) Details

Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial

Q16740

Interaction Score

O75390

(UniProtKB/Swiss-Prot/P) Details

Citrate synthase, mitochondrial

Q16740

Interaction Score

P21912

(UniProtKB/Swiss-Prot/P) Details

Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	Organelle	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial membrane (GO:0031966)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Mitochondrion	Mitochondrial inner membrane (GO:0005743)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Mitochondrion	Mitochondrial respiratory chain complex II (GO:0005749)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.992	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.992	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

DIP

Interaction Source Publication:

PubMed

Q16740

Interaction Score

P31040

(UniProtKB/Swiss-Prot/P) Details

Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Myelin sheath (GO:0043209)	0.958	Unknown: inferred from electronic annotation	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: SVM decision tree	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: pTarget method	LOCATE	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	Organelle	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial inner membrane (GO:0005743)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Mitochondrion	Mitochondrial respiratory chain complex II (GO:0005749)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	0.8	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.958	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane succinate dehydrogenase complex (GO:0045282)	0.958	Predicted: inferred from biological aspect of ancestor	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q16740

Interaction Score

0.999

Q96CU9

(UniProtKB/Swiss-Prot/P) Details

FAD-dependent oxidoreductase domain-containing protein 1

Q16740

Interaction Score

0.999

Q9H4K7

(UniProtKB/Swiss-Prot/P) Details

Mitochondrial ribosome-associated GTPase 2

Q16740

Interaction Score

0.999

O75439

(UniProtKB/Swiss-Prot/P) Details

Mitochondrial-processing peptidase subunit beta

Q16740

Interaction Score

0.999

Q92947

(UniProtKB/Swiss-Prot/P) Details

Glutaryl-CoA dehydrogenase, mitochondrial

Q16740

Interaction Score

0.999

P10109

(UniProtKB/Swiss-Prot/P) Details

Adrenodoxin, mitochondrial

Q16740

Interaction Score

0.999

P12074

(UniProtKB/Swiss-Prot/P) Details

Cytochrome c oxidase subunit 6A1, mitochondrial

Q16740

Interaction Score

0.999

P10606

(UniProtKB/Swiss-Prot/P) Details

Cytochrome c oxidase subunit 5B, mitochondrial

Q16740

Interaction Score

0.999

O95299

(UniProtKB/Swiss-Prot/P) Details

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial

Q16740

Interaction Score

0.999

Q15118

(UniProtKB/Swiss-Prot/P) Details

[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial

Q16740

Interaction Score

0.999

P13196

(UniProtKB/Swiss-Prot/P) Details

5-aminolevulinate synthase, nonspecific, mitochondrial

Q16740

Interaction Score

0.999

Q9UIJ7

(UniProtKB/Swiss-Prot/P) Details

GTP:AMP phosphotransferase AK3, mitochondrial

Q16740

Interaction Score

0.999

Q15120

(UniProtKB/Swiss-Prot/P) Details

[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial

Q16740

Interaction Score

0.999

O95831

(UniProtKB/Swiss-Prot/P) Details

Apoptosis-inducing factor 1, mitochondrial

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.79	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.79	Unknown: inferred from electronic annotation	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.998	Unknown: HDA	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.998	Experimental: experimental	Organelle	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrial intermembrane space (GO:0005758)	0.998	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrial inner membrane (GO:0005743)	0.998	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Experimental: experimental	Organelle	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.8	Experimental: experimental	eSLDB	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q16740

Interaction Score

0.999

Q9Y2S7

(UniProtKB/Swiss-Prot/P) Details

Polymerase delta-interacting protein 2

Q16740

Interaction Score

0.999

Q16762

(UniProtKB/Swiss-Prot/P) Details

Thiosulfate sulfurtransferase

Q16740

Interaction Score

0.999

Q9NVH6

(UniProtKB/Swiss-Prot/P) Details

Trimethyllysine dioxygenase, mitochondrial

Q16740

Interaction Score

0.999

O43837

(UniProtKB/Swiss-Prot/P) Details

Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial

Q16740

Interaction Score

0.999

Q9NP92

(UniProtKB/Swiss-Prot/P) Details

39S ribosomal protein S30, mitochondrial

Q16740

Interaction Score

0.999

Q9NP81

(UniProtKB/Swiss-Prot/P) Details

Serine--tRNA ligase, mitochondrial

Q16740

Interaction Score

0.999

Q9UBX3

(UniProtKB/Swiss-Prot/P) Details

Mitochondrial dicarboxylate carrier

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Experimental: experimental	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial inner membrane (GO:0005743)	0.999	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.972	Unknown: HDA	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.972	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.972	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.91	Predicted: inferred from biological aspect of ancestor	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q16740

Interaction Score

0.999

P27144

(UniProtKB/Swiss-Prot/P) Details

Adenylate kinase 4, mitochondrial

Q16740

Interaction Score

0.999

Q9Y375

(UniProtKB/Swiss-Prot/P) Details

Complex I intermediate-associated protein 30, mitochondrial

Q16740

Interaction Score

0.998

P20674

(UniProtKB/Swiss-Prot/P) Details

Cytochrome c oxidase subunit 5A, mitochondrial

Q16740

Interaction Score

0.998

P03886

(UniProtKB/Swiss-Prot/P) Details

NADH-ubiquinone oxidoreductase chain 1

Q16740

Interaction Score

0.998

Q99798

(UniProtKB/Swiss-Prot/P) Details

Aconitate hydratase, mitochondrial

Q16740

Interaction Score

0.998

O95674

(UniProtKB/Swiss-Prot/P) Details

Phosphatidate cytidylyltransferase 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.992	Experimental: experimental	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.992	Predicted: pTarget method	LOCATE	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.992	Experimental: experimental	Organelle	PubMed
Mitochondrion	Mitochondrial inner membrane (GO:0005743)	0.992	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.94	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.902	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.902	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Organelle inner membrane (GO:0019866)	0.96	Experimental: experimental	Organelle	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q16740

Interaction Score

0.998

P55809

(UniProtKB/Swiss-Prot/P) Details

Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial

Q16740

Interaction Score

0.998

Q9NZJ6

(UniProtKB/Swiss-Prot/P) Details

Ubiquinone biosynthesis O-methyltransferase, mitochondrial

Q16740

Interaction Score

0.997

Q9BQ95

(UniProtKB/Swiss-Prot/P) Details

Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

Q16740

Interaction Score

0.997

Q96I59

(UniProtKB/Swiss-Prot/P) Details

Probable asparagine--tRNA ligase, mitochondrial

Q16740

Interaction Score

0.997

Q9NVA1

(UniProtKB/Swiss-Prot/P) Details

Ubiquinol-cytochrome-c reductase complex assembly factor 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.79	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.988	Experimental: experimental	Human Proteinpedia	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.988	Predicted: pTarget method	LOCATE	PubMed
Mitochondrion	Mitochondrial inner membrane (GO:0005743)	0.988	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.79	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q16740

Interaction Score

0.997

Q96E11

(UniProtKB/Swiss-Prot/P) Details

Ribosome-recycling factor, mitochondrial

Q16740

Interaction Score

0.996

P22830

(UniProtKB/Swiss-Prot/P) Details

Ferrochelatase, mitochondrial

Q16740

Interaction Score

0.994

P03928

(UniProtKB/Swiss-Prot/P) Details

ATP synthase protein 8

Q16740

Interaction Score

0.992

Q9NWQ9

(UniProtKB/Swiss-Prot/P) Details

Uncharacterized protein C14orf119

Q16740

Interaction Score

0.991

O75570

(UniProtKB/Swiss-Prot/P) Details

Peptide chain release factor 1, mitochondrial

Q16740

Interaction Score

0.991

P30038

(UniProtKB/Swiss-Prot/P) Details

Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial

Q16740

Interaction Score

0.991

Q9NWT8

(UniProtKB/Swiss-Prot/P) Details

Aurora kinase A-interacting protein

Q16740

Interaction Score

0.991

Q9HA77

(UniProtKB/Swiss-Prot/P) Details

Probable cysteine--tRNA ligase, mitochondrial

Q16740

Interaction Score

0.988

Q8N4T8

(UniProtKB/Swiss-Prot/P) Details

Carbonyl reductase family member 4

Q16740

Interaction Score

0.988

Q9H0R6

(UniProtKB/Swiss-Prot/P) Details

Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial

Q16740

Interaction Score

0.988

Q96IX5

(UniProtKB/Swiss-Prot/P) Details

Up-regulated during skeletal muscle growth protein 5

Q16740

Interaction Score

0.988

Q9NUB1

(UniProtKB/Swiss-Prot/P) Details

Acetyl-coenzyme A synthetase 2-like, mitochondrial

Q16740

Interaction Score

0.987

Q9Y2Q3

(UniProtKB/Swiss-Prot/P) Details

Glutathione S-transferase kappa 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular (GO:0005622)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.937	Predicted: SVM decision tree	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.937	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrial matrix (GO:0005759)	0.937	Unknown: traceable author statement	GO	PubMed
Cytosol	Peroxisome (GO:0005777)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Peroxisome (GO:0005777)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Peroxisome (GO:0005777)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Peroxisomal matrix (GO:0005782)	1	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q16740

Interaction Score

0.987

Q9H2U2

(UniProtKB/Swiss-Prot/P) Details

Inorganic pyrophosphatase 2, mitochondrial

Q16740

Interaction Score

0.984

Q9BVS5

(UniProtKB/Swiss-Prot/P) Details

tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial

Q16740

Interaction Score

0.972

P67775

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Protein phosphatase type 2A complex (GO:0000159)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.86	Unknown: non-traceable author statement	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.86	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	0.902	Unknown: non-traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.902	Experimental: experimental	Organelle	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Unknown: non-traceable author statement	GO	PubMed
Cytosol	Spindle pole (GO:0000922)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Chromosome, centromeric region (GO:0000775)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.657	Unknown: non-traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Synapse (GO:0045202)	0.657	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q16740

Interaction Score

0.972

Q96I36

(UniProtKB/Swiss-Prot/P) Details

Cytochrome c oxidase assembly protein COX14

Q16740

Interaction Score

0.96

Q9BPW8

(UniProtKB/Swiss-Prot/P) Details

Protein NipSnap homolog 1

Q16740

Interaction Score

0.955

P15954

(UniProtKB/Swiss-Prot/P) Details

Cytochrome c oxidase subunit 7C, mitochondrial

Q16740

Interaction Score

0.94

P14324

(UniProtKB/Swiss-Prot/P) Details

Farnesyl pyrophosphate synthase

Q16740

Interaction Score

0.94

P51659

(UniProtKB/Swiss-Prot/P) Details

Peroxisomal multifunctional enzyme type 2

Q16740

Interaction Score

0.937

Q9UDW1

(UniProtKB/Swiss-Prot/P) Details

Cytochrome b-c1 complex subunit 9

Q16740

Interaction Score

0.93

Q96EF6

(UniProtKB/Swiss-Prot/P) Details

F-box only protein 17

Q16740

Interaction Score

0.8

Q14145

(UniProtKB/Swiss-Prot/P) Details

Kelch-like ECH-associated protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cul3-RING ubiquitin ligase complex (GO:0031463)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Midbody (GO:0030496)	0.8	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.988	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Actin filament (GO:0005884)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q16740

Interaction Score

0.8

O15392

(UniProtKB/Swiss-Prot/P) Details

Baculoviral IAP repeat-containing protein 5

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Midbody (GO:0030496)	0.8	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Spindle (GO:0005819)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Chromosome passenger complex (GO:0032133)	1	Predicted: inferred from physical interaction	GO	PubMed
Cytosol	Microtubule (GO:0005874)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Chromosome (GO:0005694)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nuclear chromosome (GO:0000228)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Chromosome, centromeric region (GO:0000775)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Condensed chromosome kinetochore (GO:0000777)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Intercellular bridge (GO:0045171)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

DIP

Interaction Source Publication:

PubMed

Q16740

Interaction Score

0.8

Q9UKB1

(UniProtKB/Swiss-Prot/P) Details

F-box/WD repeat-containing protein 11

Q16740

Interaction Score

0.8

Q16637

(UniProtKB/Swiss-Prot/P) Details

Survival motor neuron protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Perikaryon (GO:0043204)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	SMN-Sm protein complex (GO:0034719)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	SMN complex (GO:0032797)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Gemini of coiled bodies (GO:0097504)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Cajal body (GO:0015030)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Z disc (GO:0030018)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Neuron projection (GO:0043005)	0.8	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q16740

Interaction Score

0.8

P20618

(UniProtKB/Swiss-Prot/P) Details

Proteasome subunit beta type-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Proteasome complex (GO:0000502)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Proteasome core complex (GO:0005839)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Proteasome core complex, beta-subunit complex (GO:0019774)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.994	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.994	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.994	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.994	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Secretory granule lumen (GO:0034774)	0.3	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.3	Unknown: traceable author statement	GO	PubMed
Membrane	Membrane (GO:0016020)	0.8	Experimental: experimental	MatrixDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q16740

Interaction Score

0.8

Q93062

(UniProtKB/Swiss-Prot/P) Details

RNA-binding protein with multiple splicing

Q16740

Interaction Score

0.799

P20839

(UniProtKB/Swiss-Prot/P) Details

Inosine-5'-monophosphate dehydrogenase 1

Q16740

Interaction Score

0.799

P61970

(UniProtKB/Swiss-Prot/P) Details

Nuclear transport factor 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear membrane (GO:0031965)	0.979	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nuclear outer membrane (GO:0005640)	0.979	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nuclear inner membrane (GO:0005637)	0.979	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nuclear pore central transport channel (GO:0044613)	0.979	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.979	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.998	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q16740

Interaction Score

0.797

Q86UW9

(UniProtKB/Swiss-Prot/P) Details

Probable E3 ubiquitin-protein ligase DTX2

Q16740

Interaction Score

0.794

Q96K76

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin carboxyl-terminal hydrolase 47

Q16740

Interaction Score

0.778

P00533

(UniProtKB/Swiss-Prot/P) Details

Epidermal growth factor receptor

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Cell surface (GO:0009986)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Endomembrane system (GO:0012505)	0.972	Experimental: experimental	Organelle	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.972	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.994	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.994	Experimental: experimental	Organelle	PubMed
Nucleus	Nuclear membrane (GO:0031965)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.994	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.999	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Early endosome membrane (GO:0031901)	0.999	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endosome membrane (GO:0010008)	0.999	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Clathrin coated vesicle membrane (GO:0030665)	0.999	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.86	Unknown: non-traceable author statement	GO	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Membrane raft (GO:0045121)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	AP-2 adaptor complex (GO:0030122)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: pTarget method	LOCATE	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Shc-EGFR complex (GO:0070435)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Receptor complex (GO:0043235)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Apical plasma membrane (GO:0016324)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Basolateral plasma membrane (GO:0016323)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Unknown: HDA	GO	PubMed
Membrane	Synapse (GO:0045202)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q16740

Interaction Score

0.768

O00422

(UniProtKB/Swiss-Prot/P) Details

Histone deacetylase complex subunit SAP18

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
N/A	ASAP complex (GO:0061574)	0.8	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.96	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Exon-exon junction complex (GO:0035145)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Histone deacetylase complex (GO:0000118)	1	Unknown: traceable author statement	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q16740

Interaction Score

0.75

Q96BQ3

(UniProtKB/Swiss-Prot/P) Details

Tripartite motif-containing protein 43

Q16740

Interaction Score

0.728

Q68D97

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein DKFZp686C13257

Q16740

Interaction Score

0.728

Q6ZNB1

(UniProtKB/TrEmbl/P) Details

Inosine-5'-monophosphate dehydrogenase

Q16740

Interaction Score

0.7

P58557

(UniProtKB/Swiss-Prot/P) Details

Endoribonuclease YbeY

Q16740

Interaction Score

0.7

Q8TBC8

(UniProtKB/TrEmbl/P) Details

Chromosome 21 open reading frame 57, isoform CRA_b

Q16740

Interaction Score

0.7

Q7Z4N8

(UniProtKB/Swiss-Prot/P) Details

Prolyl 4-hydroxylase subunit alpha-3

Q16740

Interaction Score

0.688

O14880

(UniProtKB/Swiss-Prot/P) Details

Microsomal glutathione S-transferase 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.86	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear envelope (GO:0005635)	0.94	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.958	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.958	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.958	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.853	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.853	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.853	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Organelle membrane (GO:0031090)	0.86	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q16740

Interaction Score

0.64

A0A087X090

(UniProtKB/TrEmbl/P) Details

Farnesyl diphosphate synthase (Farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase), isoform CRA_a

Q16740

Interaction Score

0.64

P52736

(UniProtKB/Swiss-Prot/P) Details

Zinc finger protein 133

Q16740

Interaction Score

0.64

Q9BUV8

(UniProtKB/Swiss-Prot/P) Details

Uncharacterized protein RAB5IF

Q16740

Interaction Score

0.56

Q8WVK2

(UniProtKB/Swiss-Prot/P) Details

U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein

Q16740

Interaction Score

0.56

Q9NRQ2

(UniProtKB/Swiss-Prot/P) Details

Phospholipid scramblase 4

Q16740

Interaction Score

0.468

Q12805

(UniProtKB/Swiss-Prot/P) Details

EGF-containing fibulin-like extracellular matrix protein 1

Q16740

Interaction Score

0.24

Q8WYA1

(UniProtKB/Swiss-Prot/P) Details

Aryl hydrocarbon receptor nuclear translocator-like protein 2

Q16740

Interaction Score

0.24

Q9HBZ2

(UniProtKB/Swiss-Prot/P) Details

Aryl hydrocarbon receptor nuclear translocator 2

Q16740

Interaction Score

0.24

O95967

(UniProtKB/Swiss-Prot/P) Details

EGF-containing fibulin-like extracellular matrix protein 2

Q16740

Interaction Score

B7Z2I3

(UniProtKB/TrEmbl/P) Details

Receptor protein-tyrosine kinase

Q16740

Interaction Score

E7BSV0

(UniProtKB/TrEmbl/P) Details

Receptor protein-tyrosine kinase

Q16740

Interaction Score

E9PFD7

(UniProtKB/TrEmbl/P) Details

Receptor protein-tyrosine kinase

Q16740

Interaction Score

F2YGG7

(UniProtKB/TrEmbl/P) Details

Receptor protein-tyrosine kinase

Q16740

Interaction Score

Q504U8

(UniProtKB/TrEmbl/P) Details

Receptor protein-tyrosine kinase

Q16740

Interaction Score

Q3KRB6

(UniProtKB/TrEmbl/P) Details

Chromosome 20 open reading frame 44, isoform CRA_g

Q16740

Interaction Score

Q7Z3A3

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein DKFZp686M216

Q16740

Interaction Score

Q86TN1

(UniProtKB/TrEmbl/P) Details

ARNT2 protein

Q16740

Interaction Score

P30480

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, B-42 alpha chain

Q16740

Interaction Score

P01241

(UniProtKB/Swiss-Prot/P) Details

Somatotropin

Q16740

Interaction Score

Q499Y1

(UniProtKB/TrEmbl/P) Details

LOC151121 protein

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Q16740

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

Q16740

O76031

ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q16740

Q9Y697

Cysteine desulfurase, mitochondrial

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q16740

Q12931

Heat shock protein 75 kDa, mitochondrial

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q16740

P10809

60 kDa heat shock protein, mitochondrial

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q16740

P52815

39S ribosomal protein L12, mitochondrial

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q16740

O00483

Cytochrome c oxidase subunit NDUFA4

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q16740

P11310

Medium-chain specific acyl-CoA dehydrogenase, mitochondrial

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q16740

Q9UHN1

DNA polymerase subunit gamma-2, mitochondrial

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q16740

Q99643

Succinate dehydrogenase cytochrome b560 subunit, mitochondrial

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q16740

O75880

Protein SCO1 homolog, mitochondrial

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q16740

Q04837

Single-stranded DNA-binding protein, mitochondrial

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q16740

Q00059

Transcription factor A, mitochondrial

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q16740