P05230

Fibroblast growth factor 1 // UniProt Profile

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Species	H. sapiens
Number of Interactions	46 / 54
Average Interaction Score	0.886

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.958	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	0.958	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cell cortex (GO:0005938)	0.958	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.999	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.999	Predicted: pTarget method	LOCATE	PubMed
Extracellular	Extracellular region (GO:0005576)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.999	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.999	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.8	Experimental: experimental	MatrixDB	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

P05230

Interaction Score

P35052

(UniProtKB/Swiss-Prot/P) Details

Glypican-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.853	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	0.98	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.98	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi lumen (GO:0005796)	0.853	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.853	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Lysosomal lumen (GO:0043202)	0.98	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.998	Unknown: HDA	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.998	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.998	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.998	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.998	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane raft (GO:0045121)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Intrinsic to plasma membrane (GO:0031226)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Anchored to plasma membrane (GO:0046658)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.98	Unknown: HDA	GO	PubMed
Membrane	Synapse (GO:0045202)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P05230

Interaction Score

P98160

(UniProtKB/Swiss-Prot/P) Details

Basement membrane-specific heparan sulfate proteoglycan core protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.79	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	0.902	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi lumen (GO:0005796)	0.79	Unknown: traceable author statement	GO	PubMed
Cytosol	Lysosomal lumen (GO:0043202)	0.902	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.996	Unknown: HDA	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.996	Predicted: pTarget method	LOCATE	PubMed
Extracellular	Extracellular region (GO:0005576)	0.996	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.996	Unknown: HDA	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.996	Unknown: HDA	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.996	Experimental: experimental	MatrixDB	PubMed
Extracellular	Basement membrane (GO:0005604)	0.996	Unknown: traceable author statement	GO	PubMed
Membrane	Membrane (GO:0016020)	0.98	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.98	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.98	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.902	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.98	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct, MatrixDB

Interaction Source Publication:

PubMed

P05230

Interaction Score

Q03167

(UniProtKB/Swiss-Prot/P) Details

Transforming growth factor beta receptor type 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.8	Experimental: experimental	eSLDB	PubMed
Membrane	Cell surface (GO:0009986)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.657	Unknown: unspecified method	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.999	Experimental: experimental	eSLDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.999	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.999	Unknown: HDA	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.999	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Experimental: experimental	eSLDB	PubMed
Membrane	External side of plasma membrane (GO:0009897)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Inhibin-betaglycan-ActRII complex (GO:0034673)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Receptor complex (GO:0043235)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.657	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P05230

Interaction Score

P21802

(UniProtKB/Swiss-Prot/P) Details

Fibroblast growth factor receptor 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.902	Experimental: experimental	eSLDB	PubMed
Membrane	Cell surface (GO:0009986)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cell cortex (GO:0005938)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.96	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.96	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	Membrane (GO:0016020)	1	Unknown: non-traceable author statement	GO	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Unknown: non-traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Excitatory synapse (GO:0060076)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed

Interaction Source Database:

IntAct, BioGRID, DIP, HPRD

Interaction Source Publication:

PubMed

P05230

Interaction Score

Q9Y625

(UniProtKB/Swiss-Prot/P) Details

Glypican-6

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.86	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.3	Unknown: HDA	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.86	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi lumen (GO:0005796)	0.86	Unknown: traceable author statement	GO	PubMed
Cytosol	Lysosomal lumen (GO:0043202)	0.86	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.992	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.992	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.992	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.992	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.996	Experimental: experimental	eSLDB	PubMed
Membrane	Membrane (GO:0016020)	0.996	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.996	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.996	Experimental: experimental	Organelle	PubMed
Membrane	Anchored to plasma membrane (GO:0046658)	0.996	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P05230

Interaction Score

P34741

(UniProtKB/Swiss-Prot/P) Details

Syndecan-2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.86	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum lumen (GO:0005788)	0.51	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Golgi lumen (GO:0005796)	0.51	Unknown: traceable author statement	GO	PubMed
Cytosol	Lysosomal lumen (GO:0043202)	0.86	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.988	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.988	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.988	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P05230

Interaction Score

0.999

Q14512

(UniProtKB/Swiss-Prot/P) Details

Fibroblast growth factor-binding protein 1

P05230

Interaction Score

0.999

P21579

(UniProtKB/Swiss-Prot/P) Details

Synaptotagmin-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.988	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.988	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.992	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Chromaffin granule membrane (GO:0042584)	0.992	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Dense core granule (GO:0031045)	0.992	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Clathrin coated vesicle membrane (GO:0030665)	0.992	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Synaptic vesicle (GO:0008021)	0.992	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Synaptic vesicle membrane (GO:0030672)	0.992	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Secretory-pathway	Integral to synaptic vesicle membrane (GO:0030285)	0.992	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Clathrin sculpted acetylcholine transport vesicle membrane (GO:0060201)	0.992	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Clathrin sculpted glutamate transport vesicle membrane (GO:0060203)	0.992	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Clathrin sculpted monoamine transport vesicle membrane (GO:0070083)	0.992	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Clathrin sculpted gamma-aminobutyric acid transport vesicle membrane (GO:0061202)	0.992	Unknown: traceable author statement	GO	PubMed
Membrane	Neuron projection (GO:0043005)	0.989	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Neuron projection terminus (GO:0044306)	0.989	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Axon (GO:0030424)	0.989	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	SNARE complex (GO:0031201)	0.989	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.989	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Vesicle (GO:0031982)	0.988	Experimental: experimental	eSLDB	PubMed
Membrane	Cell junction (GO:0030054)	0.989	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Excitatory synapse (GO:0060076)	0.989	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Presynaptic membrane (GO:0042734)	0.989	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

HPRD, BioGRID

Interaction Source Publication:

PubMed

P05230

Interaction Score

0.999

P51654

(UniProtKB/Swiss-Prot/P) Details

Glypican-3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Endoplasmic reticulum lumen (GO:0005788)	0.51	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Golgi lumen (GO:0005796)	0.51	Unknown: traceable author statement	GO	PubMed
Cytosol	Lysosomal lumen (GO:0043202)	0.3	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.992	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.992	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.992	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.992	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Intrinsic to plasma membrane (GO:0031226)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Anchored to plasma membrane (GO:0046658)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P05230

Interaction Score

0.999

Q99584

(UniProtKB/Swiss-Prot/P) Details

Protein S100-A13

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleolus (GO:0005730)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Mast cell granule (GO:0042629)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Unknown: HDA	GO	PubMed
Extracellular	Extracellular space (GO:0005615)	0.86	Experimental: inferred from direct assay	GO	PubMed
Membrane	Membrane (GO:0016020)	0.992	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.992	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

HPRD, BioGRID

Interaction Source Publication:

PubMed

, PubMed

P05230

Interaction Score

0.999

P15880

(UniProtKB/Swiss-Prot/P) Details

40S ribosomal protein S2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	Organelle	PubMed
Cytosol	Ribonucleoprotein complex (GO:0030529)	0.999	Experimental: experimental	Organelle	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytosolic small ribosomal subunit (GO:0022627)	0.999	Unknown: HDA	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.972	Unknown: HDA	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	0.972	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.972	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.657	Unknown: HDA	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.999	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.657	Unknown: HDA	GO	PubMed
Membrane	Synapse (GO:0045202)	0.657	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed

P05230

Interaction Score

0.999

Q63HQ2

(UniProtKB/Swiss-Prot/P) Details

Pikachurin

P05230

Interaction Score

0.998

P31431

(UniProtKB/Swiss-Prot/P) Details

Syndecan-4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.86	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi lumen (GO:0005796)	0.86	Unknown: traceable author statement	GO	PubMed
Cytosol	Lysosomal lumen (GO:0043202)	0.657	Unknown: traceable author statement	GO	PubMed
Cytosol	Costamere (GO:0043034)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Membrane raft (GO:0045121)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Unknown: non-traceable author statement	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.657	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P05230

Interaction Score

0.998

P67870

(UniProtKB/Swiss-Prot/P) Details

Casein kinase II subunit beta

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.79	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Unknown: traceable author statement	GO	PubMed
Cytosol	Protein kinase CK2 complex (GO:0005956)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.986	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear matrix (GO:0016363)	0.986	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.986	Unknown: traceable author statement	GO	PubMed
Nucleus	PcG protein complex (GO:0031519)	0.986	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Secretory granule lumen (GO:0034774)	0.79	Unknown: traceable author statement	GO	PubMed
Nucleus	Chromatin (GO:0000785)	0.986	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Cilium (GO:0005929)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.3	Unknown: traceable author statement	GO	PubMed
Membrane	Membrane (GO:0016020)	0.972	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.972	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.998	Unknown: HDA	GO	PubMed

Interaction Source Database:

HPRD, BioGRID

Interaction Source Publication:

PubMed

P05230

Interaction Score

0.997

P22607

(UniProtKB/Swiss-Prot/P) Details

Fibroblast growth factor receptor 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.998	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.998	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Transport vesicle (GO:0030133)	0.998	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Unknown: traceable author statement	GO	PubMed

Interaction Source Database:

IntAct, HPRD, BioGRID, DIP

Interaction Source Publication:

PubMed

, PubMed

P05230

Interaction Score

0.995

Q96SB4

(UniProtKB/Swiss-Prot/P) Details

SRSF protein kinase 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear matrix (GO:0016363)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

P05230

Interaction Score

0.994

P11362

(UniProtKB/Swiss-Prot/P) Details

Fibroblast growth factor receptor 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.79	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.79	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Unknown: non-traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.999	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.999	Unknown: non-traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Experimental: experimental	Organelle	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	0.999	Unknown: traceable author statement	GO	PubMed
Membrane	Receptor complex (GO:0043235)	0.999	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

MatrixDB, BioGRID, DIP, IntAct, HPRD

Interaction Source Publication:

PubMed

, PubMed

P05230

Interaction Score

0.993

P78369

(UniProtKB/Swiss-Prot/P) Details

Claudin-10

P05230

Interaction Score

0.992

O43427

(UniProtKB/Swiss-Prot/P) Details

Acidic fibroblast growth factor intracellular-binding protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Endomembrane system (GO:0012505)	0.79	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.79	Predicted: SVM decision tree	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.972	Experimental: experimental	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.972	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.972	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.96	Experimental: experimental	eSLDB	PubMed
Membrane	Membrane (GO:0016020)	0.96	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

HPRD, BioGRID

Interaction Source Publication:

PubMed

P05230

Interaction Score

0.992

P22455

(UniProtKB/Swiss-Prot/P) Details

Fibroblast growth factor receptor 4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.998	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.998	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Transport vesicle (GO:0030133)	0.998	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell-cell junction (GO:0005911)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

IntAct, HPRD, DIP, BioGRID

Interaction Source Publication:

PubMed

, PubMed

P05230

Interaction Score

0.983

E9PBI9

(UniProtKB/TrEmbl/P) Details

Syndecan

P05230

Interaction Score

0.981

P19784

(UniProtKB/Swiss-Prot/P) Details

Casein kinase II subunit alpha'

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.997	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.997	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.997	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.997	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.997	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.996	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	PcG protein complex (GO:0031519)	0.996	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Acrosomal vesicle (GO:0001669)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Chromatin (GO:0000785)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.3	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, HPRD

Interaction Source Publication:

PubMed

P05230

Interaction Score

0.962

P61758

(UniProtKB/Swiss-Prot/P) Details

Prefoldin subunit 3

P05230

Interaction Score

0.956

P68400

(UniProtKB/Swiss-Prot/P) Details

Casein kinase II subunit alpha

P05230

Interaction Score

0.953

D2CGD1

(UniProtKB/TrEmbl/P) Details

Fibroblast growth factor receptor

P05230

Interaction Score

0.945

P38646

(UniProtKB/Swiss-Prot/P) Details

Stress-70 protein, mitochondrial

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Myelin sheath (GO:0043209)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.51	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	Organelle	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial matrix (GO:0005759)	1	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrial nucleoid (GO:0042645)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.8	Experimental: experimental	MatrixDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.51	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.51	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID, HPRD

Interaction Source Publication:

PubMed

P05230

Interaction Score

0.928

Q0IJ44

(UniProtKB/TrEmbl/P) Details

Receptor protein-tyrosine kinase

P05230

Interaction Score

0.916

H7C410

(UniProtKB/TrEmbl/P) Details

Glypican-1

P05230

Interaction Score

0.912

Q8NI16

(UniProtKB/TrEmbl/P) Details

Receptor protein-tyrosine kinase

P05230

Interaction Score

0.892

Q16089

(UniProtKB/TrEmbl/P) Details

Fibroblast growth factor 1

P05230

Interaction Score

0.836

O60341

(UniProtKB/Swiss-Prot/P) Details

Lysine-specific histone demethylase 1A

P05230

Interaction Score

0.836

Q9UKL0

(UniProtKB/Swiss-Prot/P) Details

REST corepressor 1

P05230

Interaction Score

0.822

R4GMQ1

(UniProtKB/TrEmbl/P) Details

Lysine-specific histone demethylase 1A

P05230

Interaction Score

0.8

A0A0S2Z3Q6

(UniProtKB/TrEmbl/P) Details

Receptor protein-tyrosine kinase

P05230

Interaction Score

0.8

A0A024R9D1

(UniProtKB/TrEmbl/P) Details

Syndecan

P05230

Interaction Score

0.8

A0A141AXF1

(UniProtKB/TrEmbl/P) Details

Fibroblast growth factor receptor

P05230

Interaction Score

0.8

B4E1S6

(UniProtKB/TrEmbl/P) Details

Syndecan

P05230

Interaction Score

0.8

B4DVP5

(UniProtKB/TrEmbl/P) Details

Fibroblast growth factor receptor

P05230

Interaction Score

0.8

J3KPQ0

(UniProtKB/TrEmbl/P) Details

Fibroblast growth factor receptor

P05230

Interaction Score

0.769

Q9NP66

(UniProtKB/Swiss-Prot/P) Details

High mobility group protein 20A

P05230

Interaction Score

0.766

S4R381

(UniProtKB/TrEmbl/P) Details

Fibroblast growth factor receptor 2

P05230

Interaction Score

0.658

Q59F20

(UniProtKB/TrEmbl/P) Details

Neuropilin-1 variant

P05230

Interaction Score

0.64

A8K147

(UniProtKB/TrEmbl/P) Details

Multifunctional fusion protein

P05230

Interaction Score

0.64

Q53H15

(UniProtKB/TrEmbl/P) Details

Glypican 3 variant

P05230

Interaction Score

0.3

Q9P2K3

(UniProtKB/Swiss-Prot/P) Details

REST corepressor 3

P05230

Interaction Score

0.295

Q14687

(UniProtKB/Swiss-Prot/P) Details

Genetic suppressor element 1

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P05230

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

P05230

P35052

Glypican-1

Localizations:

Interaction Source Database:

Interaction Source Publication:

P05230

P98160

Basement membrane-specific heparan sulfate proteoglycan core protein

Localizations:

Interaction Source Database:

Interaction Source Publication:

P05230

Q03167

Transforming growth factor beta receptor type 3

Localizations:

Interaction Source Database:

Interaction Source Publication:

P05230

P21802

Fibroblast growth factor receptor 2

Localizations:

Interaction Source Database:

Interaction Source Publication:

P05230

Q9Y625

Glypican-6

Localizations:

Interaction Source Database:

Interaction Source Publication:

P05230

P34741

Syndecan-2

Localizations:

Interaction Source Database:

Interaction Source Publication:

P05230

Q14512

Fibroblast growth factor-binding protein 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

P05230

P21579

Synaptotagmin-1

Localizations:

Interaction Source Database:

Interaction Source Publication:

P05230

P51654

Glypican-3

Localizations:

Interaction Source Database:

Interaction Source Publication:

P05230

Q99584

Protein S100-A13

Localizations:

Interaction Source Database:

Interaction Source Publication:

P05230

P15880

40S ribosomal protein S2

Localizations:

Interaction Source Database:

Interaction Source Publication:

P05230

Q63HQ2

Pikachurin

Localizations:

Interaction Source Database:

Interaction Source Publication:

P05230