P27037

Activin receptor type-2A    //   UniProt Profile 

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Species

 H. sapiens

Number of Interactions

 53 / 70

Average Interaction Score

 0.901

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Cell surface (GO:0009986) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.96 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.999 Experimental: experimental eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.999 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.999 Experimental: experimental Organelle PubMed 
Membrane Inhibin-betaglycan-ActRII complex (GO:0034673) 0.999 Experimental: inferred from direct assay GO PubMed 
Membrane Integral to plasma membrane (GO:0005887) 0.999 Unknown: traceable author statement GO PubMed 
Membrane Receptor complex (GO:0043235) 0.999 Predicted: inferred from physical interaction GO PubMed 

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.


Interactions

All Details

P27037

Interaction Score
1

Q96RT1

(UniProtKB/Swiss-Prot/P) Details

Erbin

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.94 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nuclear membrane (GO:0031965) 1 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nuclear speck (GO:0016607) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear speck (GO:0016607) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.972 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular matrix (GO:0031012) 0.972 Experimental: experimental MatrixDB PubMed 
Extracellular Basement membrane (GO:0005604) 0.972 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Human Proteinpedia PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Basolateral plasma membrane (GO:0016323) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Basal plasma membrane (GO:0009925) 1 Unknown: non-traceable author statement GO PubMed 
Membrane Hemidesmosome (GO:0030056) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Cell junction (GO:0030054) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Neuromuscular junction (GO:0031594) 1 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P27037

Interaction Score
1

Q86UL8

(UniProtKB/Swiss-Prot/P) Details

Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.982 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.982 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 0.982 Predicted: inferred from sequence or structural similarity GO PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Experimental: inferred from direct assay GO PubMed 
Nucleus Macromolecular complex (GO:0032991) 0.94 Predicted: inferred from sequence or structural similarity GO PubMed 
Secretory-pathway Late endosome (GO:0005770) 0.7 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Dendrite (GO:0030425) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Postsynaptic density (GO:0014069) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 1 Experimental: experimental eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Slit diaphragm (GO:0036057) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Tight junction (GO:0005923) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Synapse (GO:0045202) 1 Predicted: inferred from sequence or structural similarity GO PubMed 

Interaction Source Database:

BioGRID, HPRD

Interaction Source Publication:

PubMed , PubMed 

P27037

Interaction Score
1

P36896

(UniProtKB/Swiss-Prot/P) Details

Activin receptor type-1B

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Cell surface (GO:0009986) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.96 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Experimental: experimental eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 1 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: pTarget method LOCATE PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane Integral to plasma membrane (GO:0005887) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Receptor complex (GO:0043235) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Activin receptor complex (GO:0048179) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

DIP, BioGRID

Interaction Source Publication:

PubMed , PubMed 

P27037

Interaction Score
1

Q8N6C5

(UniProtKB/Swiss-Prot/P) Details

Immunoglobulin superfamily member 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.958 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.958 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.958 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Membrane (GO:0016020) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Membrane (GO:0016020) 1 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Human Proteinpedia PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

HPRD, BioGRID

Interaction Source Publication:

PubMed 

P27037

Interaction Score
1

O60603

(UniProtKB/Swiss-Prot/P) Details

Toll-like receptor 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Cell surface (GO:0009986) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cell body (GO:0044297) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.86 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.902 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Phagocytic vesicle membrane (GO:0030670) 0.902 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Secretory granule membrane (GO:0030667) 0.902 Unknown: traceable author statement GO PubMed 
Membrane Cell projection (GO:0042995) 1 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Experimental: experimental eSLDB PubMed 
Membrane Membrane raft (GO:0045121) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: pTarget method LOCATE PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Toll-like receptor 1-Toll-like receptor 2 protein complex (GO:0035354) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Intrinsic to plasma membrane (GO:0031226) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Integral to plasma membrane (GO:0005887) 1 Unknown: traceable author statement GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P27037

Interaction Score
1

Q03167

(UniProtKB/Swiss-Prot/P) Details

Transforming growth factor beta receptor type 3

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.8 Experimental: experimental eSLDB PubMed 
Membrane Cell surface (GO:0009986) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.657 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytosol (GO:0005829) 0.657 Unknown: unspecified method The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.999 Experimental: experimental eSLDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.999 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.999 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 0.999 Unknown: HDA GO PubMed 
Extracellular Extracellular matrix (GO:0031012) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular matrix (GO:0031012) 0.999 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 1 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Experimental: experimental eSLDB PubMed 
Membrane External side of plasma membrane (GO:0009897) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Inhibin-betaglycan-ActRII complex (GO:0034673) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Integral to plasma membrane (GO:0005887) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Receptor complex (GO:0043235) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.657 Unknown: HDA GO PubMed 

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed 

P27037

Interaction Score
1

P37023

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein kinase receptor R3

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Cell surface (GO:0009986) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Neuronal cell body (GO:0043025) 0.79 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Lysosome (GO:0005764) 0.79 Predicted: pTarget method LOCATE PubMed 
Membrane Dendrite (GO:0030425) 1 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Predicted: SVM decision tree eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: pTarget method LOCATE PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane Integral to plasma membrane (GO:0005887) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

DIP, HPRD

Interaction Source Publication:

PubMed 

P27037

Interaction Score
1

Q04771

(UniProtKB/Swiss-Prot/P) Details

Activin receptor type-1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Apical part of cell (GO:0045177) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytosol (GO:0005829) 0.86 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleolus (GO:0005730) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Experimental: experimental eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: pTarget method LOCATE PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane Integral to plasma membrane (GO:0005887) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Activin receptor complex (GO:0048179) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

DIP, BioGRID

Interaction Source Publication:

PubMed , PubMed 

P27037

Interaction Score
1

P37173

(UniProtKB/Swiss-Prot/P) Details

TGF-beta receptor type-2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.3 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Membrane raft (GO:0045121) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane External side of plasma membrane (GO:0009897) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Caveola (GO:0005901) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Receptor complex (GO:0043235) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Transforming growth factor beta receptor complex (GO:0070022) 1 Unknown: inferred by curator GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P27037

Interaction Score
1

P17813

(UniProtKB/Swiss-Prot/P) Details

Endoglin

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.992 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.992 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 0.992 Experimental: inferred from direct assay GO PubMed 
Extracellular Endothelial microparticle (GO:0072563) 0.992 Unknown: inferred from electronic annotation GO PubMed 
Membrane Membrane (GO:0016020) 1 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Predicted: SVM decision tree eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane External side of plasma membrane (GO:0009897) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Receptor complex (GO:0043235) 1 Predicted: inferred from physical interaction GO PubMed 
Membrane Transforming growth factor beta receptor complex (GO:0070022) 1 Unknown: inferred by curator GO PubMed 
Membrane Focal adhesion (GO:0005925) 1 Unknown: HDA GO PubMed 

Interaction Source Database:

HPRD, BioGRID

Interaction Source Publication:

PubMed 

P27037

Interaction Score
0.999

P43115

(UniProtKB/Swiss-Prot/P) Details

Prostaglandin E2 receptor EP3 subtype

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Endomembrane system (GO:0012505) 0.8 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 0.86 Experimental: experimental Organelle PubMed 
Nucleus Nuclear envelope (GO:0005635) 0.86 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.994 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.994 Unknown: non-traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.994 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.994 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 0.994 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to plasma membrane (GO:0005887) 0.994 Unknown: traceable author statement GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P27037

Interaction Score
0.999

P05111

(UniProtKB/Swiss-Prot/P) Details

Inhibin alpha chain

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.8 Experimental: experimental eSLDB PubMed 
Membrane Photoreceptor inner segment (GO:0001917) 0.98 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Neuronal cell body (GO:0043025) 0.902 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.902 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.902 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Photoreceptor outer segment (GO:0001750) 0.98 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.958 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.958 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Inhibin A complex (GO:0043512) 0.958 Experimental: inferred from direct assay GO PubMed 
Membrane Membrane (GO:0016020) 0.98 Experimental: experimental MatrixDB PubMed 
Membrane Inhibin-betaglycan-ActRII complex (GO:0034673) 0.98 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P27037

Interaction Score
0.999

O95393

(UniProtKB/Swiss-Prot/P) Details

Bone morphogenetic protein 10

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.8 Experimental: experimental eSLDB PubMed 
Membrane Cell surface (GO:0009986) 0.96 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.96 Experimental: inferred from direct assay GO PubMed 
Cytosol Z disc (GO:0030018) 0.96 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.987 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.987 Predicted: pTarget method LOCATE PubMed 
Extracellular Extracellular region (GO:0005576) 0.987 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 0.987 Experimental: inferred from direct assay GO PubMed 
Membrane Membrane (GO:0016020) 0.96 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P27037

Interaction Score
0.999

P12643

(UniProtKB/Swiss-Prot/P) Details

Bone morphogenetic protein 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.8 Experimental: experimental eSLDB PubMed 
Membrane Cell surface (GO:0009986) 0.96 Experimental: inferred from direct assay GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.96 Experimental: inferred from direct assay GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.987 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.987 Predicted: pTarget method LOCATE PubMed 
Extracellular Extracellular region (GO:0005576) 0.987 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 0.987 Experimental: inferred from direct assay GO PubMed 
Membrane Membrane (GO:0016020) 0.96 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

DIP

Interaction Source Publication:

PubMed 

P27037

Interaction Score
0.999

A8MVW5

(UniProtKB/Swiss-Prot/P) Details

HEPACAM family member 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Midbody (GO:0030496) 0.958 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.86 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Golgi membrane (GO:0000139) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Spindle (GO:0005819) 0.96 Experimental: inferred from direct assay GO PubMed 
Cytosol Centrosome (GO:0005813) 0.96 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to membrane (GO:0016021) 0.958 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.958 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P27037

Interaction Score
0.998

Q9H158

(UniProtKB/Swiss-Prot/P) Details

Protocadherin alpha-C1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleolus (GO:0005730) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to membrane (GO:0016021) 0.958 Predicted: SVM decision tree eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.958 Experimental: experimental Organelle PubMed 
Membrane Integral to plasma membrane (GO:0005887) 0.958 Unknown: traceable author statement GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P27037

Interaction Score
0.997

O15165

(UniProtKB/Swiss-Prot/P) Details

Low-density lipoprotein receptor class A domain-containing protein 4

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.988 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.988 Experimental: inferred from direct assay GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.988 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.988 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.988 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.988 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Early endosome membrane (GO:0031901) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.86 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.86 Unknown: non-traceable author statement GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P27037

Interaction Score
0.996

Q96GQ5

(UniProtKB/Swiss-Prot/P) Details

RUS1 family protein C16orf58

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleolus (GO:0005730) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.853 Unknown: HDA GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.853 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.853 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P27037

Interaction Score
0.995

Q6NW40

(UniProtKB/Swiss-Prot/P) Details

RGM domain family member B

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleoplasm (GO:0005654) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Endoplasmic reticulum-Golgi intermediate compartment (GO:0005793) 0.7 Predicted: inferred from sequence or structural similarity GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to membrane (GO:0016021) 0.981 Predicted: SVM decision tree eSLDB PubMed 
Membrane Membrane raft (GO:0045121) 0.981 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.981 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Anchored to plasma membrane (GO:0046658) 0.981 Predicted: inferred from sequence or structural similarity GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P27037

Interaction Score
0.995

Q8TDQ0

(UniProtKB/Swiss-Prot/P) Details

Hepatitis A virus cellular receptor 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Cell surface (GO:0009986) 0.979 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Early endosome (GO:0005769) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to membrane (GO:0016021) 0.979 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.979 Unknown: inferred from electronic annotation GO PubMed 
Membrane Immunological synapse (GO:0001772) 0.979 Unknown: inferred from electronic annotation GO PubMed 
Membrane Cell junction (GO:0030054) 0.979 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P27037

Interaction Score
0.993

P18075

(UniProtKB/Swiss-Prot/P) Details

Bone morphogenetic protein 7

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.8 Experimental: experimental eSLDB PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.86 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleolus (GO:0005730) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.998 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.998 Predicted: pTarget method LOCATE PubMed 
Extracellular Extracellular region (GO:0005576) 0.998 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 0.998 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular matrix (GO:0031012) 0.998 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular matrix (GO:0031012) 0.998 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 
Cytosol Vesicle (GO:0031982) 0.86 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P27037

Interaction Score
0.992

P09529

(UniProtKB/Swiss-Prot/P) Details

Inhibin beta B chain

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.8 Experimental: experimental eSLDB PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 0.8 Experimental: inferred from direct assay GO PubMed 
Membrane Cell periphery (GO:0071944) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.937 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.937 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 0.937 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Membrane (GO:0016020) 0.86 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

BioGRID, HPRD

Interaction Source Publication:

PubMed , PubMed 

P27037

Interaction Score
0.99

Q9NU53

(UniProtKB/Swiss-Prot/P) Details

Glycoprotein integral membrane protein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Fibrillar center (GO:0001650) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.972 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.972 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.972 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P27037

Interaction Score
0.989

O00220

(UniProtKB/Swiss-Prot/P) Details

Tumor necrosis factor receptor superfamily member 10A

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Cell surface (GO:0009986) 0.958 Experimental: inferred from direct assay GO PubMed 
Cytosol Intracellular (GO:0005622) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.958 Unknown: traceable author statement GO PubMed 
Membrane Integral to plasma membrane (GO:0005887) 0.958 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P27037

Interaction Score
0.985

Q96G30

(UniProtKB/Swiss-Prot/P) Details

Melanocortin-2 receptor accessory protein 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.86 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.958 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.958 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.958 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P27037

Interaction Score
0.978

Q9UK05

(UniProtKB/Swiss-Prot/P) Details

Growth/differentiation factor 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.8 Experimental: experimental eSLDB PubMed 
Cytosol Cell (GO:0005623) 0.51 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.981 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.981 Predicted: pTarget method LOCATE PubMed 
Extracellular Extracellular region (GO:0005576) 0.981 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 0.981 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.51 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P27037

Interaction Score
0.972

P22004

(UniProtKB/Swiss-Prot/P) Details

Bone morphogenetic protein 6

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.8 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.51 Unknown: inferred from electronic annotation GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.91 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 0.91 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 
Cytosol Vesicle (GO:0031982) 0.51 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID, HPRD

Interaction Source Publication:

PubMed 

P27037

Interaction Score
0.971

P43026

(UniProtKB/Swiss-Prot/P) Details

Growth/differentiation factor 5

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.8 Experimental: experimental eSLDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.996 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.996 Predicted: pTarget method LOCATE PubMed 
Extracellular Extracellular region (GO:0005576) 0.996 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.996 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 0.996 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Membrane (GO:0016020) 0.86 Experimental: experimental MatrixDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.86 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID, HPRD

Interaction Source Publication:

PubMed 

P27037

Interaction Score
0.971

P08476

(UniProtKB/Swiss-Prot/P) Details

Inhibin beta A chain

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.8 Experimental: experimental eSLDB PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.998 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.998 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Inhibin A complex (GO:0043512) 0.998 Experimental: inferred from direct assay GO PubMed 
Extracellular Activin A complex (GO:0043509) 0.998 Experimental: inferred from direct assay GO PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

DIP, HPRD, BioGRID

Interaction Source Publication:

PubMed , PubMed , PubMed 

P27037

Interaction Score
0.968

O60383

(UniProtKB/Swiss-Prot/P) Details

Growth/differentiation factor 9

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.8 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.973 Predicted: pTarget method LOCATE PubMed 
Extracellular Extracellular region (GO:0005576) 0.973 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 0.973 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed 

P27037

Interaction Score
0.964

Q5JR98

(UniProtKB/Swiss-Prot/P) Details

Tctex1 domain-containing protein 4

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.853 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.937 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.937 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.937 Predicted: pTarget method LOCATE PubMed 
Secretory-pathway Acrosomal vesicle (GO:0001669) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Microtubule organizing center (GO:0005815) 0.853 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Axoneme (GO:0005930) 0.853 Unknown: inferred from electronic annotation GO PubMed 
Membrane Sperm flagellum (GO:0036126) 0.8 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed 

P27037

Interaction Score
0.958

Q86T65

(UniProtKB/Swiss-Prot/P) Details

Disheveled-associated activator of morphogenesis 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.997 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.997 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.997 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.997 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.997 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P27037

Interaction Score
0.957

P55103

(UniProtKB/Swiss-Prot/P) Details

Inhibin beta C chain

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.8 Experimental: experimental eSLDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.981 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.981 Predicted: pTarget method LOCATE PubMed 
Extracellular Extracellular region (GO:0005576) 0.981 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 0.981 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed 

P27037

Interaction Score
0.952

Q86TG7

(UniProtKB/Swiss-Prot/P) Details

Retrotransposon-derived protein PEG10

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.992 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.992 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.992 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.988 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.988 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.988 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P27037

Interaction Score
0.952

Q9Y3C5

(UniProtKB/Swiss-Prot/P) Details

RING finger protein 11

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Ubiquitin ligase complex (GO:0000151) 0.992 Experimental: inferred from direct assay GO PubMed 
Cytosol Ubiquitin ligase complex (GO:0000151) 0.992 Experimental: experimental Organelle PubMed 
Cytosol Cytoplasm (GO:0005737) 0.992 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Recycling endosome (GO:0055037) 0.51 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Early endosome (GO:0005769) 0.51 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.992 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P27037

Interaction Score
0.928

P57105

(UniProtKB/Swiss-Prot/P) Details

Synaptojanin-2-binding protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Mitochondrion Mitochondrion (GO:0005739) 0.998 Experimental: experimental eSLDB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.998 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.998 Predicted: PAML algorithm PA-GOSUB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.998 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Mitochondrion Integral to mitochondrial outer membrane (GO:0031307) 0.998 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.8 Experimental: experimental eSLDB PubMed 

Interaction Source Database:

HPRD, BioGRID

Interaction Source Publication:

PubMed , PubMed 

P27037

Interaction Score
0.922

A0A0J9YYF7

(UniProtKB/TrEmbl/P) Details

Disheveled-associated activator of morphogenesis 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P27037

Interaction Score
0.92

Q9UER7

(UniProtKB/Swiss-Prot/P) Details

Death domain-associated protein 6

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.958 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.958 Unknown: traceable author statement GO PubMed 
Cytosol Cytosol (GO:0005829) 0.958 Predicted: inferred from sequence or structural similarity GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleolus (GO:0005730) 1 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Unknown: traceable author statement GO PubMed 
Nucleus Nuclear body (GO:0016604) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear body (GO:0016604) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus PML body (GO:0016605) 1 Unknown: traceable author statement GO PubMed 
Nucleus Chromosome, centromeric region (GO:0000775) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

P27037

Interaction Score
0.909

O00325

(UniProtKB/TrEmbl/P) Details

Prostaglandin E receptor 3 (Subtype EP3), isoform CRA_g

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Integral to membrane (GO:0016021) 0.91 Predicted: SVM decision tree eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.91 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P27037

Interaction Score
0.898

Q9UI38

(UniProtKB/Swiss-Prot/P) Details

Probable threonine protease PRSS50

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.94 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.8 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.94 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P27037

Interaction Score
0.892

A3QNQ0

(UniProtKB/TrEmbl/P) Details

TGF-beta receptor type-2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P27037

Interaction Score
0.874

Q96JM4

(UniProtKB/Swiss-Prot/P) Details

Leucine-rich repeat and IQ domain-containing protein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P27037

Interaction Score
0.799

Q96CG0

(UniProtKB/TrEmbl/P) Details

ENG protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Integral to membrane (GO:0016021) 0.8 Experimental: experimental eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P27037

Interaction Score
0.768

B4DSP0

(UniProtKB/TrEmbl/P) Details

HCG1642748, isoform CRA_b

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P27037

Interaction Score
0.768

Q53F85

(UniProtKB/TrEmbl/P) Details

Death-associated protein 6 variant

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.8 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.8 Experimental: experimental eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P27037

Interaction Score
0.699

J3KNF6

(UniProtKB/TrEmbl/P) Details

RGM domain family member B

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleoplasm (GO:0005654) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Integral to membrane (GO:0016021) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P27037

Interaction Score
0.699

Q5T9B9

(UniProtKB/TrEmbl/P) Details

Endoglin (Osler-Rendu-Weber syndrome 1), isoform CRA_b

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Integral to membrane (GO:0016021) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P27037

Interaction Score
0.64

D2JYI1

(UniProtKB/TrEmbl/P) Details

TGF-beta receptor type-2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P27037

Interaction Score
0.64

D3DPA4

(UniProtKB/TrEmbl/P) Details

Serine/threonine-protein kinase receptor

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P27037

Interaction Score
0.64

B3KWR9

(UniProtKB/TrEmbl/P) Details

Toll-like receptor

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P27037

Interaction Score
0.64

A0A0S2Z4S4

(UniProtKB/TrEmbl/P) Details

Toll-like receptor

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P27037

Interaction Score
0.56

A4D1W7

(UniProtKB/TrEmbl/P) Details

Inhibin, beta A (Activin A, activin AB alpha polypeptide), isoform CRA_a

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.8 Experimental: experimental eSLDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.7 Predicted: pTarget method LOCATE PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P27037

Interaction Score
0

Q4VBA3

(UniProtKB/TrEmbl/P) Details

BMP6 protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.8 Experimental: experimental eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

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ComPPI is published in Nucleic Acids Research Database Issue 2015