P61073

C-X-C chemokine receptor type 4    //   UniProt Profile 

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Species

H. sapiens

Number of Interactions

119 / 137

Average Interaction Score

0.933

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Cell leading edge (GO:0031252) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Cell surface (GO:0009986) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.902 Unknown: traceable author statement GO PubMed 
Nucleus Macromolecular complex (GO:0032991) 0.8 Experimental: inferred from mutant phenotype GO PubMed 
Secretory-pathway Early endosome (GO:0005769) 0.992 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Late endosome (GO:0005770) 0.992 Experimental: inferred from direct assay GO PubMed 
Cytosol Lysosome (GO:0005764) 0.902 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Cytoplasmic vesicle (GO:0031410) 0.992 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.902 Unknown: HDA GO PubMed 
Membrane Cell junction (GO:0030054) 1 Unknown: inferred from electronic annotation GO PubMed 

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Interactions

All Details

P61073

Interaction Score
1

Q03135

(UniProtKB/Swiss-Prot/P) Details

Caveolin-1

P61073

Interaction Score
1

P04233

(UniProtKB/Swiss-Prot/P) Details

HLA class II histocompatibility antigen gamma chain

P61073

Interaction Score
1

P61769

(UniProtKB/Swiss-Prot/P) Details

Beta-2-microglobulin

P61073

Interaction Score
1

Q9NQ11

(UniProtKB/Swiss-Prot/P) Details

Cation-transporting ATPase 13A2

P61073

Interaction Score
1

Q92633

(UniProtKB/Swiss-Prot/P) Details

Lysophosphatidic acid receptor 1

P61073

Interaction Score
1

O60603

(UniProtKB/Swiss-Prot/P) Details

Toll-like receptor 2

P61073

Interaction Score
1

P01730

(UniProtKB/Swiss-Prot/P) Details

T-cell surface glycoprotein CD4

P61073

Interaction Score
1

P27487

(UniProtKB/Swiss-Prot/P) Details

Dipeptidyl peptidase 4

P61073

Interaction Score
1

P35579

(UniProtKB/Swiss-Prot/P) Details

Myosin-9

P61073

Interaction Score
1

P63096

(UniProtKB/Swiss-Prot/P) Details

Guanine nucleotide-binding protein G(i) subunit alpha-1

P61073

Interaction Score
1

P40259

(UniProtKB/Swiss-Prot/P) Details

B-cell antigen receptor complex-associated protein beta chain

P61073

Interaction Score
1

O60674

(UniProtKB/Swiss-Prot/P) Details

Tyrosine-protein kinase JAK2

P61073

Interaction Score
1

P07237

(UniProtKB/Swiss-Prot/P) Details

Protein disulfide-isomerase

P61073

Interaction Score
1

P32121

(UniProtKB/Swiss-Prot/P) Details

Beta-arrestin-2

P61073

Interaction Score
1

Q04900

(UniProtKB/Swiss-Prot/P) Details

Sialomucin core protein 24

P61073

Interaction Score
1

P31431

(UniProtKB/Swiss-Prot/P) Details

Syndecan-4

P61073

Interaction Score
1

P21589

(UniProtKB/Swiss-Prot/P) Details

5'-nucleotidase

P61073

Interaction Score
1

Q05397

(UniProtKB/Swiss-Prot/P) Details

Focal adhesion kinase 1

P61073

Interaction Score
1

P08311

(UniProtKB/Swiss-Prot/P) Details

Cathepsin G

P61073

Interaction Score
1

P16284

(UniProtKB/Swiss-Prot/P) Details

Platelet endothelial cell adhesion molecule

P61073

Interaction Score
1

Q31612

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, B-73 alpha chain

P61073

Interaction Score
1

P08246

(UniProtKB/Swiss-Prot/P) Details

Neutrophil elastase

P61073

Interaction Score
1

Q9Y3E0

(UniProtKB/Swiss-Prot/P) Details

Vesicle transport protein GOT1B

P61073

Interaction Score
1

P51681

(UniProtKB/Swiss-Prot/P) Details

C-C chemokine receptor type 5

P61073

Interaction Score
1

P08575

(UniProtKB/Swiss-Prot/P) Details

Receptor-type tyrosine-protein phosphatase C

P61073

Interaction Score
1

P11142

(UniProtKB/Swiss-Prot/P) Details

Heat shock cognate 71 kDa protein

P61073

Interaction Score
1

P43005

(UniProtKB/Swiss-Prot/P) Details

Excitatory amino acid transporter 3

P61073

Interaction Score
1

Q16643

(UniProtKB/Swiss-Prot/P) Details

Drebrin

P61073

Interaction Score
1

Q16288

(UniProtKB/Swiss-Prot/P) Details

NT-3 growth factor receptor

P61073

Interaction Score
1

Q14344

(UniProtKB/Swiss-Prot/P) Details

Guanine nucleotide-binding protein subunit alpha-13

P61073

Interaction Score
1

O43505

(UniProtKB/Swiss-Prot/P) Details

Beta-1,4-glucuronyltransferase 1

P61073

Interaction Score
1

Q96J02

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase Itchy homolog

P61073

Interaction Score
1

P54578

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin carboxyl-terminal hydrolase 14

P61073

Interaction Score
1

Q5T3F8

(UniProtKB/Swiss-Prot/P) Details

CSC1-like protein 2

P61073

Interaction Score
1

P29350

(UniProtKB/Swiss-Prot/P) Details

Tyrosine-protein phosphatase non-receptor type 6

P61073

Interaction Score
1

O95395

(UniProtKB/Swiss-Prot/P) Details

Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3

P61073

Interaction Score
0.999

P52333

(UniProtKB/Swiss-Prot/P) Details

Tyrosine-protein kinase JAK3

P61073

Interaction Score
0.999

P01889

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, B-7 alpha chain

P61073

Interaction Score
0.999

P52630

(UniProtKB/Swiss-Prot/P) Details

Signal transducer and activator of transcription 2

P61073

Interaction Score
0.999

P41587

(UniProtKB/Swiss-Prot/P) Details

Vasoactive intestinal polypeptide receptor 2

P61073

Interaction Score
0.999

O95715

(UniProtKB/Swiss-Prot/P) Details

C-X-C motif chemokine 14

P61073

Interaction Score
0.998

P32302

(UniProtKB/Swiss-Prot/P) Details

C-X-C chemokine receptor type 5

P61073

Interaction Score
0.998

P42224

(UniProtKB/Swiss-Prot/P) Details

Signal transducer and activator of transcription 1-alpha/beta

P61073

Interaction Score
0.998

P23458

(UniProtKB/Swiss-Prot/P) Details

Tyrosine-protein kinase JAK1

P61073

Interaction Score
0.998

P48061

(UniProtKB/Swiss-Prot/P) Details

Stromal cell-derived factor 1

P61073

Interaction Score
0.996

P40763

(UniProtKB/Swiss-Prot/P) Details

Signal transducer and activator of transcription 3

P61073

Interaction Score
0.994

Q8WV48

(UniProtKB/Swiss-Prot/P) Details

Coiled-coil domain-containing protein 107

P61073

Interaction Score
0.993

Q92783

(UniProtKB/Swiss-Prot/P) Details

Signal transducing adapter molecule 1

P61073

Interaction Score
0.992

P35626

(UniProtKB/Swiss-Prot/P) Details

Beta-adrenergic receptor kinase 2

P61073

Interaction Score
0.985

P30460

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, B-8 alpha chain

P61073

Interaction Score
0.985

P30462

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, B-14 alpha chain

P61073

Interaction Score
0.985

P30475

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, B-39 alpha chain

P61073

Interaction Score
0.985

P30479

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, B-41 alpha chain

P61073

Interaction Score
0.985

Q95365

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, B-38 alpha chain

P61073

Interaction Score
0.981

P15498

(UniProtKB/Swiss-Prot/P) Details

Proto-oncogene vav

P61073

Interaction Score
0.98

Q06124

(UniProtKB/Swiss-Prot/P) Details

Tyrosine-protein phosphatase non-receptor type 11

P61073

Interaction Score
0.98

O15524

(UniProtKB/Swiss-Prot/P) Details

Suppressor of cytokine signaling 1

P61073

Interaction Score
0.979

Q9H8X2

(UniProtKB/Swiss-Prot/P) Details

Inositol-pentakisphosphate 2-kinase

P61073

Interaction Score
0.978

Q8N4D4

(UniProtKB/TrEmbl/P) Details

Cation-transporting ATPase

P61073

Interaction Score
0.978

Q8NBS1

(UniProtKB/TrEmbl/P) Details

Cation-transporting ATPase

P61073

Interaction Score
0.978

Q59GN8

(UniProtKB/TrEmbl/P) Details

PTK2 protein tyrosine kinase 2 isoform b variant

P61073

Interaction Score
0.978

P51692

(UniProtKB/Swiss-Prot/P) Details

Signal transducer and activator of transcription 5B

P61073

Interaction Score
0.973

Q8N433

(UniProtKB/TrEmbl/P) Details

G protein-coupled receptor kinase

P61073

Interaction Score
0.973

O43312

(UniProtKB/Swiss-Prot/P) Details

Metastasis suppressor protein 1

P61073

Interaction Score
0.955

O14543

(UniProtKB/Swiss-Prot/P) Details

Suppressor of cytokine signaling 3

P61073

Interaction Score
0.95

P30480

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, B-42 alpha chain

P61073

Interaction Score
0.95

P30486

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, B-48 alpha chain

P61073

Interaction Score
0.95

Q29836

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, B-67 alpha chain

P61073

Interaction Score
0.95

Q31610

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, B-81 alpha chain

P61073

Interaction Score
0.944

P10244

(UniProtKB/Swiss-Prot/P) Details

Myb-related protein B

P61073

Interaction Score
0.94

A0N0R2

(UniProtKB/TrEmbl/P) Details

Burkitt lymphoma receptor 1, GTP binding protein (Chemokine (C-X-C motif) receptor 5), isoform CRA_a

P61073

Interaction Score
0.94

Q2YD84

(UniProtKB/TrEmbl/P) Details

Chemokine (C-X-C motif) receptor 5

P61073

Interaction Score
0.928

P30484

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, B-46 alpha chain

P61073

Interaction Score
0.926

P03989

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, B-27 alpha chain

P61073

Interaction Score
0.926

P10319

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, B-58 alpha chain

P61073

Interaction Score
0.926

P18463

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, B-37 alpha chain

P61073

Interaction Score
0.926

P18464

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, B-51 alpha chain

P61073

Interaction Score
0.926

P18465

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, B-57 alpha chain

P61073

Interaction Score
0.926

P30461

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, B-13 alpha chain

P61073

Interaction Score
0.926

P30464

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, B-15 alpha chain

P61073

Interaction Score
0.926

P30466

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, B-18 alpha chain

P61073

Interaction Score
0.926

P30481

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, B-44 alpha chain

P61073

Interaction Score
0.926

P30483

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, B-45 alpha chain

P61073

Interaction Score
0.926

P30485

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, B-47 alpha chain

P61073

Interaction Score
0.926

P30487

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, B-49 alpha chain

P61073

Interaction Score
0.926

P30488

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, B-50 alpha chain

P61073

Interaction Score
0.926

P30490

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, B-52 alpha chain

P61073

Interaction Score
0.926

P30491

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, B-53 alpha chain

P61073

Interaction Score
0.926

P30492

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, B-54 alpha chain

P61073

Interaction Score
0.926

P30493

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, B-55 alpha chain

P61073

Interaction Score
0.926

P30495

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, B-56 alpha chain

P61073

Interaction Score
0.926

P30498

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, B-78 alpha chain

P61073

Interaction Score
0.926

P30685

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, B-35 alpha chain

P61073

Interaction Score
0.926

Q04826

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, B-40 alpha chain

P61073

Interaction Score
0.926

Q29718

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, B-82 alpha chain

P61073

Interaction Score
0.926

Q29940

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, B-59 alpha chain

P61073

Interaction Score
0.924

Q8WVE6

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 171

P61073

Interaction Score
0.916

B7Z7U4

(UniProtKB/TrEmbl/P) Details

Tyrosine-protein kinase receptor

P61073

Interaction Score
0.912

Q6NZX3

(UniProtKB/TrEmbl/P) Details

5'-nucleotidase, ecto

P61073

Interaction Score
0.901

P50502

(UniProtKB/Swiss-Prot/P) Details

Hsc70-interacting protein

P61073

Interaction Score
0.892

Q2TNI1

(UniProtKB/TrEmbl/P) Details

Caveolin

P61073

Interaction Score
0.892

Q59E85

(UniProtKB/TrEmbl/P) Details

Caveolin

P61073

Interaction Score
0.892

Q7Z4F3

(UniProtKB/TrEmbl/P) Details

Caveolin

P61073

Interaction Score
0.886

Q658W2

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein DKFZp666O0110

P61073

Interaction Score
0.838

Q6FI39

(UniProtKB/TrEmbl/P) Details

SOCS3 protein

P61073

Interaction Score
0.8

Q38L21

(UniProtKB/TrEmbl/P) Details

C-C chemokine receptor type 5

P61073

Interaction Score
0.8

Q5VZX0

(UniProtKB/TrEmbl/P) Details

Endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2, isoform CRA_a

P61073

Interaction Score
0.769

Q8IZP2

(UniProtKB/Swiss-Prot/P) Details

Putative protein FAM10A4

P61073

Interaction Score
0.722

Q0IJ56

(UniProtKB/TrEmbl/P) Details

ST13 protein

P61073

Interaction Score
0.7

Q96CY4

(UniProtKB/TrEmbl/P) Details

Neurotrophic tyrosine kinase, receptor, type 3, isoform CRA_e

P61073

Interaction Score
0.64

A0A024R7M7

(UniProtKB/TrEmbl/P) Details

Tyrosine-protein kinase

P61073

Interaction Score
0.64

A8K910

(UniProtKB/TrEmbl/P) Details

Tyrosine-protein kinase

P61073

Interaction Score
0.64

B4DYV1

(UniProtKB/TrEmbl/P) Details

Tyrosine-protein kinase

P61073

Interaction Score
0.64

A0A024R757

(UniProtKB/TrEmbl/P) Details

Caveolin

P61073

Interaction Score
0.64

A9XTE5

(UniProtKB/TrEmbl/P) Details

Caveolin

P61073

Interaction Score
0.64

X5D2R1

(UniProtKB/TrEmbl/P) Details

Tyrosine-protein kinase receptor

P61073

Interaction Score
0.64

X5D7M5

(UniProtKB/TrEmbl/P) Details

Tyrosine-protein kinase receptor

P61073

Interaction Score
0.64

X5DNW6

(UniProtKB/TrEmbl/P) Details

Tyrosine-protein kinase receptor

P61073

Interaction Score
0.631

Q59GM6

(UniProtKB/TrEmbl/P) Details

PTK2 protein tyrosine kinase 2 isoform b variant

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ComPPI is published in Nucleic Acids Research Database Issue 2015