P78334

Gamma-aminobutyric acid receptor subunit epsilon // UniProt Profile

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Species	H. sapiens
Number of Interactions	81 / 102
Average Interaction Score	0.853

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Chloride channel complex (GO:0034707)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.998	Predicted: pTarget method	LOCATE	PubMed
Membrane	Plasma membrane (GO:0005886)	0.998	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Cell junction (GO:0030054)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Postsynaptic membrane (GO:0045211)	0.998	Unknown: inferred from electronic annotation	GO	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

P78334

Interaction Score

0.999

P52569

(UniProtKB/Swiss-Prot/P) Details

Cationic amino acid transporter 2

P78334

Interaction Score

0.999

O60353

(UniProtKB/Swiss-Prot/P) Details

Frizzled-6

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle membrane (GO:0030659)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: pTarget method	LOCATE	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Apicolateral plasma membrane (GO:0016327)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Apical plasma membrane (GO:0016324)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P78334

Interaction Score

0.999

Q9NR82

(UniProtKB/Swiss-Prot/P) Details

Potassium voltage-gated channel subfamily KQT member 5

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Voltage-gated potassium channel complex (GO:0008076)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Clathrin coat (GO:0030118)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: pTarget method	LOCATE	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P78334

Interaction Score

0.999

Q14332

(UniProtKB/Swiss-Prot/P) Details

Frizzled-2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.8	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear body (GO:0016604)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Clathrin-coated endocytic vesicle membrane (GO:0030669)	0.3	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Cell junction (GO:0030054)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P78334

Interaction Score

0.999

Q13433

(UniProtKB/Swiss-Prot/P) Details

Zinc transporter ZIP6

P78334

Interaction Score

0.999

P04920

(UniProtKB/Swiss-Prot/P) Details

Anion exchange protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear speck (GO:0016607)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.999	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.999	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	0.999	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Apical plasma membrane (GO:0016324)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Basolateral plasma membrane (GO:0016323)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.999	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P78334

Interaction Score

0.999

P54760

(UniProtKB/Swiss-Prot/P) Details

Ephrin type-B receptor 4

P78334

Interaction Score

0.998

Q13586

(UniProtKB/Swiss-Prot/P) Details

Stromal interaction molecule 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Sarcoplasmic reticulum membrane (GO:0033017)	0.86	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.999	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Cortical endoplasmic reticulum (GO:0032541)	0.999	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.999	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Integral to endoplasmic reticulum membrane (GO:0030176)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule (GO:0005874)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.998	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.998	Experimental: experimental	Organelle	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	0.998	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P78334

Interaction Score

0.998

Q15842

(UniProtKB/Swiss-Prot/P) Details

ATP-sensitive inward rectifier potassium channel 8

P78334

Interaction Score

0.998

P01891

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, A-68 alpha chain

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	0.992	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.989	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Integral to lumenal side of endoplasmic reticulum membrane (GO:0071556)	0.989	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.989	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.989	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Recycling endosome membrane (GO:0055038)	0.989	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Early endosome membrane (GO:0031901)	0.989	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Phagocytic vesicle membrane (GO:0030670)	0.989	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	ER to Golgi transport vesicle membrane (GO:0012507)	0.989	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.992	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.992	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	MHC class I protein complex (GO:0042612)	0.992	Predicted: inferred from sequence or structural similarity	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P78334

Interaction Score

0.997

P16188

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, A-30 alpha chain

P78334

Interaction Score

0.996

Q86X29

(UniProtKB/Swiss-Prot/P) Details

Lipolysis-stimulated lipoprotein receptor

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.987	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.987	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.987	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.931	Experimental: experimental	MatrixDB	PubMed
Extracellular	Low-density lipoprotein particle (GO:0034362)	0.931	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Very-low-density lipoprotein particle (GO:0034361)	0.931	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Chylomicron (GO:0042627)	0.931	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.987	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.987	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.987	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.987	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.987	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P78334

Interaction Score

0.995

P13746

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, A-11 alpha chain

P78334

Interaction Score

0.995

Q96AE7

(UniProtKB/Swiss-Prot/P) Details

Tetratricopeptide repeat protein 17

P78334

Interaction Score

0.993

P04439

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, A-3 alpha chain

P78334

Interaction Score

0.989

Q5JRA6

(UniProtKB/Swiss-Prot/P) Details

Transport and Golgi organization protein 1 homolog

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.994	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.996	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.996	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endoplasmic reticulum exit site (GO:0070971)	0.994	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum lumen (GO:0005788)	0.994	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.994	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Lysosome (GO:0005764)	0.996	Predicted: pTarget method	LOCATE	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Membrane (GO:0016020)	0.958	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.958	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.958	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P78334

Interaction Score

0.985

P30447

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, A-23 alpha chain

P78334

Interaction Score

0.984

Q96CP6

(UniProtKB/Swiss-Prot/P) Details

GRAM domain-containing protein 1A

P78334

Interaction Score

0.983

O60427

(UniProtKB/Swiss-Prot/P) Details

Fatty acid desaturase 1

P78334

Interaction Score

0.977

P01892

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, A-2 alpha chain

P78334

Interaction Score

0.975

P13224

(UniProtKB/Swiss-Prot/P) Details

Platelet glycoprotein Ib beta chain

P78334

Interaction Score

0.973

Q9NRU3

(UniProtKB/Swiss-Prot/P) Details

Metal transporter CNNM1

P78334

Interaction Score

0.964

Q8TEQ8

(UniProtKB/Swiss-Prot/P) Details

GPI ethanolamine phosphate transferase 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Endomembrane system (GO:0012505)	0.8	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleolus (GO:0005730)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.996	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.996	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.996	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.996	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.902	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.902	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.902	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P78334

Interaction Score

0.964

Q9BX95

(UniProtKB/Swiss-Prot/P) Details

Sphingosine-1-phosphate phosphatase 1

P78334

Interaction Score

0.949

Q9H3K2

(UniProtKB/Swiss-Prot/P) Details

Growth hormone-inducible transmembrane protein

P78334

Interaction Score

0.949

Q9H3S5

(UniProtKB/Swiss-Prot/P) Details

GPI mannosyltransferase 1

P78334

Interaction Score

0.949

Q9Y3B3

(UniProtKB/Swiss-Prot/P) Details

Transmembrane emp24 domain-containing protein 7

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum-Golgi intermediate compartment (GO:0005793)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum-Golgi intermediate compartment membrane (GO:0033116)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	COPI vesicle coat (GO:0030126)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	COPII vesicle coat (GO:0030127)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Transport vesicle (GO:0030133)	1	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.86	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.86	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P78334

Interaction Score

0.949

P81408

(UniProtKB/Swiss-Prot/P) Details

Protein FAM189B

P78334

Interaction Score

0.947

Q9H6U8

(UniProtKB/Swiss-Prot/P) Details

Alpha-1,2-mannosyltransferase ALG9

P78334

Interaction Score

0.947

Q96S66

(UniProtKB/Swiss-Prot/P) Details

Chloride channel CLIC-like protein 1

P78334

Interaction Score

0.947

Q7Z2K6

(UniProtKB/Swiss-Prot/P) Details

Endoplasmic reticulum metallopeptidase 1

P78334

Interaction Score

0.947

Q9NUT2

(UniProtKB/Swiss-Prot/P) Details

ATP-binding cassette sub-family B member 8, mitochondrial

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Experimental: experimental	Organelle	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial envelope (GO:0005740)	0.999	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrial inner membrane (GO:0005743)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleolus (GO:0005730)	0.992	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.853	Unknown: traceable author statement	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.853	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	ATP-binding cassette (ABC) transporter complex (GO:0043190)	0.853	Unknown: traceable author statement	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P78334

Interaction Score

0.947

Q96FL8

(UniProtKB/Swiss-Prot/P) Details

Multidrug and toxin extrusion protein 1

P78334

Interaction Score

0.947

Q9BU23

(UniProtKB/Swiss-Prot/P) Details

Lipase maturation factor 2

P78334

Interaction Score

0.927

Q59GF1

(UniProtKB/TrEmbl/P) Details

Anion exchange protein

P78334

Interaction Score

0.927

Q13948

(UniProtKB/Swiss-Prot/P) Details

Protein CASP

P78334

Interaction Score

0.927

Q9Y227

(UniProtKB/Swiss-Prot/P) Details

Ectonucleoside triphosphate diphosphohydrolase 4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Endomembrane system (GO:0012505)	0.998	Experimental: experimental	Organelle	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.999	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.999	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Integral to Golgi membrane (GO:0030173)	0.999	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Integral to Golgi membrane (GO:0030173)	0.999	Experimental: experimental	Organelle	PubMed
Cytosol	Vacuole (GO:0005773)	0.998	Experimental: experimental	eSLDB	PubMed
Cytosol	Lysosome (GO:0005764)	0.998	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.8	Experimental: experimental	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P78334

Interaction Score

0.925

P10314

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, A-32 alpha chain

P78334

Interaction Score

0.925

P10316

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, A-69 alpha chain

P78334

Interaction Score

0.925

P16189

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, A-31 alpha chain

P78334

Interaction Score

0.925

P16190

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, A-33 alpha chain

P78334

Interaction Score

0.925

P18462

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, A-25 alpha chain

P78334

Interaction Score

0.925

P30453

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, A-34 alpha chain

P78334

Interaction Score

0.925

P30456

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, A-43 alpha chain

P78334

Interaction Score

0.925

P30457

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, A-66 alpha chain

P78334

Interaction Score

0.925

P30459

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, A-74 alpha chain

P78334

Interaction Score

0.925

P30512

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, A-29 alpha chain

P78334

Interaction Score

0.924

P67812

(UniProtKB/Swiss-Prot/P) Details

Signal peptidase complex catalytic subunit SEC11A

P78334

Interaction Score

0.924

O43292

(UniProtKB/Swiss-Prot/P) Details

Glycosylphosphatidylinositol anchor attachment 1 protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Endomembrane system (GO:0012505)	0.94	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.998	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.998	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.998	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Integral to endoplasmic reticulum membrane (GO:0030176)	0.998	Experimental: experimental	Organelle	PubMed
Secretory-pathway	GPI-anchor transamidase complex (GO:0042765)	0.998	Unknown: traceable author statement	GO	PubMed
Cytosol	Lysosome (GO:0005764)	0.94	Predicted: pTarget method	LOCATE	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.79	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.79	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P78334

Interaction Score

0.924

Q6ZXV5

(UniProtKB/Swiss-Prot/P) Details

Transmembrane and TPR repeat-containing protein 3

P78334

Interaction Score

0.924

Q15005

(UniProtKB/Swiss-Prot/P) Details

Signal peptidase complex subunit 2

P78334

Interaction Score

0.924

Q9Y6A1

(UniProtKB/Swiss-Prot/P) Details

Protein O-mannosyl-transferase 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Endomembrane system (GO:0012505)	0.86	Experimental: experimental	Organelle	PubMed
Cytosol	Sarcoplasmic reticulum (GO:0016529)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Acrosomal vesicle (GO:0001669)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.79	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.79	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P78334

Interaction Score

0.924

B7ZAQ6

(UniProtKB/Swiss-Prot/P) Details

Golgi pH regulator A

P78334

Interaction Score

0.924

P0CG08

(UniProtKB/Swiss-Prot/P) Details

Golgi pH regulator B

P78334

Interaction Score

0.924

Q96D05

(UniProtKB/Swiss-Prot/P) Details

Uncharacterized protein FAM241B

P78334

Interaction Score

0.924

Q9NV64

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 39A

P78334

Interaction Score

0.908

O78126

(UniProtKB/TrEmbl/P) Details

MHC class I HLA-A

P78334

Interaction Score

0.908

Q96L35

(UniProtKB/TrEmbl/P) Details

EPH receptor B4, isoform CRA_b

P78334

Interaction Score

0.892

P30450

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, A-26 alpha chain

P78334

Interaction Score

0.892

Q96G97

(UniProtKB/Swiss-Prot/P) Details

Seipin

P78334

Interaction Score

0.826

Q9ULG6

(UniProtKB/Swiss-Prot/P) Details

Cell cycle progression protein 1

P78334

Interaction Score

0.799

P39880

(UniProtKB/Swiss-Prot/P) Details

Homeobox protein cut-like 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.3	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.998	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.998	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.998	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.8	Experimental: experimental	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P78334

Interaction Score

0.799

Q3LIA3

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein Nbla10317

P78334

Interaction Score

0.799

M0QZ12

(UniProtKB/TrEmbl/P) Details

GRAM domain-containing protein 1A

P78334

Interaction Score

0.799

Q86UZ8

(UniProtKB/TrEmbl/P) Details

FZD2 protein

P78334

Interaction Score

0.799

Q541P7

(UniProtKB/TrEmbl/P) Details

EPH receptor B4, isoform CRA_a

P78334

Interaction Score

0.752

P05534

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, A-24 alpha chain

P78334

Interaction Score

0.752

P30455

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, A-36 alpha chain

P78334

Interaction Score

0.752

Q09160

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, A-80 alpha chain

P78334

Interaction Score

0.748

P0C7V7

(UniProtKB/Swiss-Prot/P) Details

Putative signal peptidase complex catalytic subunit SEC11B

P78334

Interaction Score

0.748

P14866

(UniProtKB/Swiss-Prot/P) Details

Heterogeneous nuclear ribonucleoprotein L

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Ribonucleoprotein complex (GO:0030529)	0.999	Experimental: experimental	Organelle	PubMed
Cytosol	Ribonucleoprotein granule (GO:0035770)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.999	Experimental: experimental	Human Proteinpedia	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.999	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

P78334

Interaction Score

0.699

Q6MZP1

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein DKFZp686D20222

P78334

Interaction Score

0.699

Q6ZMD3

(UniProtKB/TrEmbl/P) Details

cDNA FLJ23992 fis, clone HRC08583

P78334

Interaction Score

0.699

A0A0A0MR51

(UniProtKB/TrEmbl/P) Details

Fatty acid desaturase 1

P78334

Interaction Score

0.64

A0A024RC78

(UniProtKB/TrEmbl/P) Details

Signal peptidase complex catalytic subunit SEC11

P78334

Interaction Score

0.64

P30443

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, A-1 alpha chain

P78334

Interaction Score

H0YKT4

(UniProtKB/TrEmbl/P) Details

Signal peptidase complex catalytic subunit SEC11A

P78334

Interaction Score

P08397

(UniProtKB/Swiss-Prot/P) Details

Porphobilinogen deaminase

P78334

Interaction Score

G0XQ39

(UniProtKB/TrEmbl/P) Details

STIM1L

P78334

Interaction Score

Q9Y6J7

(UniProtKB/TrEmbl/P) Details

Cote1

P78334

Interaction Score

Q6NTA2

(UniProtKB/TrEmbl/P) Details

HNRNPL protein

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P78334

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

P78334

P52569

Cationic amino acid transporter 2

Localizations:

Interaction Source Database:

Interaction Source Publication:

P78334

O60353

Frizzled-6

Localizations:

Interaction Source Database:

Interaction Source Publication:

P78334

Q9NR82

Potassium voltage-gated channel subfamily KQT member 5

Localizations:

Interaction Source Database:

Interaction Source Publication:

P78334

Q14332

Frizzled-2

Localizations:

Interaction Source Database:

Interaction Source Publication:

P78334

Q13433

Zinc transporter ZIP6

Localizations:

Interaction Source Database:

Interaction Source Publication:

P78334

P04920

Anion exchange protein 2

Localizations:

Interaction Source Database:

Interaction Source Publication:

P78334

P54760

Ephrin type-B receptor 4

Localizations:

Interaction Source Database:

Interaction Source Publication:

P78334

Q13586

Stromal interaction molecule 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

P78334

Q15842

ATP-sensitive inward rectifier potassium channel 8

Localizations:

Interaction Source Database:

Interaction Source Publication:

P78334

P01891

HLA class I histocompatibility antigen, A-68 alpha chain

Localizations:

Interaction Source Database:

Interaction Source Publication:

P78334

P16188

HLA class I histocompatibility antigen, A-30 alpha chain

Localizations:

Interaction Source Database:

Interaction Source Publication:

P78334

Q86X29

Lipolysis-stimulated lipoprotein receptor

Localizations:

Interaction Source Database:

Interaction Source Publication:

P78334