Q5SZD1

Uncharacterized protein C6orf141 // UniProt Profile

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Species	H. sapiens
Number of Interactions	104 / 146
Average Interaction Score	0.843

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nuclear membrane (GO:0031965)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

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Interactions

All Details

Q5SZD1

Interaction Score

0.982

P51587

(UniProtKB/Swiss-Prot/P) Details

Breast cancer type 2 susceptibility protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	BRCA2-MAGE-D1 complex (GO:0033593)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Secretory granule (GO:0030141)	0.8	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear chromosome, telomeric region (GO:0000784)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Lateral element (GO:0000800)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q5SZD1

Interaction Score

0.982

Q9Y6D9

(UniProtKB/Swiss-Prot/P) Details

Mitotic spindle assembly checkpoint protein MAD1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.997	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nuclear membrane (GO:0031965)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear envelope (GO:0005635)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear pore (GO:0005643)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.997	Experimental: experimental	Organelle	PubMed
Cytosol	Spindle (GO:0005819)	0.997	Unknown: non-traceable author statement	GO	PubMed
Cytosol	Mitotic spindle (GO:0072686)	0.997	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Mitotic spindle pole (GO:0097431)	0.997	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	0.997	Unknown: non-traceable author statement	GO	PubMed
Nucleus	Condensed chromosome kinetochore (GO:0000777)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Kinetochore (GO:0000776)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q5SZD1

Interaction Score

0.982

O75376

(UniProtKB/Swiss-Prot/P) Details

Nuclear receptor corepressor 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Transcriptional repressor complex (GO:0017053)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Histone deacetylase complex (GO:0000118)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Sin3 complex (GO:0016580)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Spindle microtubule (GO:0005876)	0.992	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear chromatin (GO:0000790)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q5SZD1

Interaction Score

0.982

Q9Y3I1

(UniProtKB/Swiss-Prot/P) Details

F-box only protein 7

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Ubiquitin ligase complex (GO:0000151)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Ubiquitin ligase complex (GO:0000151)	1	Experimental: experimental	Organelle	PubMed
Cytosol	SCF ubiquitin ligase complex (GO:0019005)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.8	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.998	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q5SZD1

Interaction Score

0.981

Q92540

(UniProtKB/Swiss-Prot/P) Details

Protein SMG7

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Telomerase holoenzyme complex (GO:0005697)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Intermediate filament cytoskeleton (GO:0045111)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intermediate filament cytoskeleton (GO:0045111)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q5SZD1

Interaction Score

0.981

Q5VUA4

(UniProtKB/Swiss-Prot/P) Details

Zinc finger protein 318

Q5SZD1

Interaction Score

0.981

Q7Z4H7

(UniProtKB/Swiss-Prot/P) Details

HAUS augmin-like complex subunit 6

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nuclear speck (GO:0016607)	0.996	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Spindle (GO:0005819)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	HAUS complex (GO:0070652)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule (GO:0005874)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q5SZD1

Interaction Score

0.981

O15379

(UniProtKB/Swiss-Prot/P) Details

Histone deacetylase 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.972	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.972	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Transcriptional repressor complex (GO:0017053)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Histone deacetylase complex (GO:0000118)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.96	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Spindle microtubule (GO:0005876)	0.972	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.8	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q5SZD1

Interaction Score

0.981

Q8NEZ3

(UniProtKB/Swiss-Prot/P) Details

WD repeat-containing protein 19

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.971	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.971	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.971	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Intraflagellar transport particle A (GO:0030991)	0.971	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cilium (GO:0005929)	0.981	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Motile cilium (GO:0031514)	0.981	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Photoreceptor connecting cilium (GO:0032391)	0.981	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Photoreceptor outer segment (GO:0001750)	0.981	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q5SZD1

Interaction Score

0.981

Q9UPR3

(UniProtKB/Swiss-Prot/P) Details

Protein SMG5

Q5SZD1

Interaction Score

0.98

P56282

(UniProtKB/Swiss-Prot/P) Details

DNA polymerase epsilon subunit 2

Q5SZD1

Interaction Score

0.98

Q9UJX4

(UniProtKB/Swiss-Prot/P) Details

Anaphase-promoting complex subunit 5

Q5SZD1

Interaction Score

0.98

Q9HBM1

(UniProtKB/Swiss-Prot/P) Details

Kinetochore protein Spc25

Q5SZD1

Interaction Score

0.979

O15350

(UniProtKB/Swiss-Prot/P) Details

Tumor protein p73

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.94	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.94	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Transcription factor complex (GO:0005667)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.96	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Chromatin (GO:0000785)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.8	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q5SZD1

Interaction Score

0.979

Q8NBT2

(UniProtKB/Swiss-Prot/P) Details

Kinetochore protein Spc24

Q5SZD1

Interaction Score

0.979

Q96BY7

(UniProtKB/Swiss-Prot/P) Details

Autophagy-related protein 2 homolog B

Q5SZD1

Interaction Score

0.979

Q13107

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin carboxyl-terminal hydrolase 4

Q5SZD1

Interaction Score

0.979

O00443

(UniProtKB/Swiss-Prot/P) Details

Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Unknown: traceable author statement	GO	PubMed
Cytosol	Phosphatidylinositol 3-kinase complex (GO:0005942)	0.998	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Clathrin-coated vesicle (GO:0030136)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.86	Unknown: HDA	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.86	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Vesicle (GO:0031982)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.998	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q5SZD1

Interaction Score

0.978

Q9P2F8

(UniProtKB/Swiss-Prot/P) Details

Signal-induced proliferation-associated 1-like protein 2

Q5SZD1

Interaction Score

0.978

O75792

(UniProtKB/Swiss-Prot/P) Details

Ribonuclease H2 subunit A

Q5SZD1

Interaction Score

0.978

Q9H7S9

(UniProtKB/Swiss-Prot/P) Details

Zinc finger protein 703

Q5SZD1

Interaction Score

0.977

O43379

(UniProtKB/Swiss-Prot/P) Details

WD repeat-containing protein 62

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	U5 snRNP (GO:0005682)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.982	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Precatalytic spliceosome (GO:0071011)	0.982	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Catalytic step 2 spliceosome (GO:0071013)	0.982	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Spindle pole (GO:0000922)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centriole (GO:0005814)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q5SZD1

Interaction Score

0.974

Q96RR4

(UniProtKB/Swiss-Prot/P) Details

Calcium/calmodulin-dependent protein kinase kinase 2

Q5SZD1

Interaction Score

0.974

O60907

(UniProtKB/Swiss-Prot/P) Details

F-box-like/WD repeat-containing protein TBL1X

Q5SZD1

Interaction Score

0.973

Q15750

(UniProtKB/Swiss-Prot/P) Details

TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

Q5SZD1

Interaction Score

0.973

O14628

(UniProtKB/Swiss-Prot/P) Details

Zinc finger protein 195

Q5SZD1

Interaction Score

0.971

Q9BWN1

(UniProtKB/Swiss-Prot/P) Details

Proline-rich protein 14

Q5SZD1

Interaction Score

0.971

Q99871

(UniProtKB/Swiss-Prot/P) Details

HAUS augmin-like complex subunit 7

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleolus (GO:0005730)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Spindle (GO:0005819)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	HAUS complex (GO:0070652)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Microtubule (GO:0005874)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q5SZD1

Interaction Score

0.971

Q15042

(UniProtKB/Swiss-Prot/P) Details

Rab3 GTPase-activating protein catalytic subunit

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Lipid particle (GO:0005811)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.96	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum tubular network (GO:0071782)	0.972	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.972	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.972	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.999	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q5SZD1

Interaction Score

0.969

Q9NXX6

(UniProtKB/Swiss-Prot/P) Details

Non-structural maintenance of chromosomes element 4 homolog A

Q5SZD1

Interaction Score

0.969

P46108

(UniProtKB/Swiss-Prot/P) Details

Adapter molecule crk

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.978	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.978	Unknown: inferred by curator	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.978	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.978	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.958	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.958	Experimental: experimental	Organelle	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.958	Predicted: inferred from physical interaction	GO	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	0.978	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane raft (GO:0045121)	0.971	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.971	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.971	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.971	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.978	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

Q5SZD1

Interaction Score

0.965

Q9BVV6

(UniProtKB/Swiss-Prot/P) Details

Protein TALPID3

Q5SZD1

Interaction Score

0.96

A5PL33

(UniProtKB/Swiss-Prot/P) Details

Protein KRBA1

Q5SZD1

Interaction Score

0.957

Q4KWH8

(UniProtKB/Swiss-Prot/P) Details

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1

Q5SZD1

Interaction Score

0.957

Q15468

(UniProtKB/Swiss-Prot/P) Details

SCL-interrupting locus protein

Q5SZD1

Interaction Score

0.955

Q12929

(UniProtKB/Swiss-Prot/P) Details

Epidermal growth factor receptor kinase substrate 8

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.987	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cell cortex (GO:0005938)	0.987	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Stereocilium (GO:0032420)	0.987	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Growth cone (GO:0030426)	0.897	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Ruffle membrane (GO:0032587)	0.897	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Cytosol	Vesicle (GO:0031982)	0.987	Unknown: HDA	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.987	Unknown: HDA	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.897	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Synapse (GO:0045202)	0.897	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

Q5SZD1

Interaction Score

0.952

Q9BZD4

(UniProtKB/Swiss-Prot/P) Details

Kinetochore protein Nuf2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.3	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Chromosome (GO:0005694)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Chromosome, centromeric region (GO:0000775)	1	Unknown: non-traceable author statement	GO	PubMed
Nucleus	Condensed chromosome kinetochore (GO:0000777)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Ndc80 complex (GO:0031262)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q5SZD1

Interaction Score

0.942

O60437

(UniProtKB/Swiss-Prot/P) Details

Periplakin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.86	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.999	Experimental: experimental	Organelle	PubMed
Cytosol	Cornified envelope (GO:0001533)	0.999	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.86	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.999	Unknown: HDA	GO	PubMed
Membrane	Desmosome (GO:0030057)	0.86	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q5SZD1

Interaction Score

0.941

Q3B7T1

(UniProtKB/Swiss-Prot/P) Details

Erythroid differentiation-related factor 1

Q5SZD1

Interaction Score

0.94

Q9Y2X9

(UniProtKB/Swiss-Prot/P) Details

Zinc finger protein 281

Q5SZD1

Interaction Score

0.94

Q9UPW6

(UniProtKB/Swiss-Prot/P) Details

DNA-binding protein SATB2

Q5SZD1

Interaction Score

0.94

Q6W2J9

(UniProtKB/Swiss-Prot/P) Details

BCL-6 corepressor

Q5SZD1

Interaction Score

0.938

Q96AV8

(UniProtKB/Swiss-Prot/P) Details

Transcription factor E2F7

Q5SZD1

Interaction Score

0.935

Q14149

(UniProtKB/Swiss-Prot/P) Details

MORC family CW-type zinc finger protein 3

Q5SZD1

Interaction Score

0.926

Q68CZ6

(UniProtKB/Swiss-Prot/P) Details

HAUS augmin-like complex subunit 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.96	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Spindle (GO:0005819)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Mitotic spindle (GO:0072686)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	HAUS complex (GO:0070652)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule (GO:0005874)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Intercellular bridge (GO:0045171)	0.96	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Intercellular bridge (GO:0045171)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q5SZD1

Interaction Score

0.926

Q9UJC3

(UniProtKB/Swiss-Prot/P) Details

Protein Hook homolog 1

Q5SZD1

Interaction Score

0.926

Q14315

(UniProtKB/Swiss-Prot/P) Details

Filamin-C

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Sarcoplasm (GO:0016528)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.8	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Costamere (GO:0043034)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Z disc (GO:0030018)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.994	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.994	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Sarcolemma (GO:0042383)	0.994	Experimental: inferred from direct assay	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.994	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q5SZD1

Interaction Score

0.926

P68366

(UniProtKB/Swiss-Prot/P) Details

Tubulin alpha-4A chain

Q5SZD1

Interaction Score

0.923

Q13554

(UniProtKB/Swiss-Prot/P) Details

Calcium/calmodulin-dependent protein kinase type II subunit beta

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Sarcoplasmic reticulum membrane (GO:0033017)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.79	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.79	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endocytic vesicle membrane (GO:0030666)	0.3	Unknown: traceable author statement	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Neuron projection (GO:0043005)	0.996	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.996	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Cell junction (GO:0030054)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Synapse (GO:0045202)	0.996	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q5SZD1

Interaction Score

0.922

Q9NYZ3

(UniProtKB/Swiss-Prot/P) Details

G2 and S phase-expressed protein 1

Q5SZD1

Interaction Score

0.922

Q13557

(UniProtKB/Swiss-Prot/P) Details

Calcium/calmodulin-dependent protein kinase type II subunit delta

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.997	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.997	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.997	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Sarcoplasmic reticulum membrane (GO:0033017)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.997	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.997	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.79	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.79	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endocytic vesicle membrane (GO:0030666)	0.3	Unknown: traceable author statement	GO	PubMed
Membrane	Neuron projection (GO:0043005)	0.996	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.996	Unknown: HDA	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.996	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Sarcolemma (GO:0042383)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q5SZD1

Interaction Score

0.915

Q86SX3

(UniProtKB/Swiss-Prot/P) Details

Tubulin epsilon and delta complex protein 1

Q5SZD1

Interaction Score

0.897

Q96SN8

(UniProtKB/Swiss-Prot/P) Details

CDK5 regulatory subunit-associated protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.8	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Unknown: non-traceable author statement	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Spindle pole (GO:0000922)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Mitotic spindle pole (GO:0097431)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Pericentriolar material (GO:0000242)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Gamma-tubulin ring complex (GO:0008274)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule (GO:0005874)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule plus end (GO:0035371)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q5SZD1

Interaction Score

0.897

Q15149

(UniProtKB/Swiss-Prot/P) Details

Plectin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Sarcoplasm (GO:0016528)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Costamere (GO:0043034)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Intermediate filament cytoskeleton (GO:0045111)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intermediate filament cytoskeleton (GO:0045111)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Brush border (GO:0005903)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Unknown: non-traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Sarcolemma (GO:0042383)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Hemidesmosome (GO:0030056)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q5SZD1

Interaction Score

0.897

Q3V6T2

(UniProtKB/Swiss-Prot/P) Details

Girdin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.998	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.998	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cilium basal body (GO:0036064)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	0.999	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Centriole (GO:0005814)	0.999	Experimental: inferred from direct assay	GO	PubMed
Membrane	Lamellipodium (GO:0030027)	0.992	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.992	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.992	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q5SZD1

Interaction Score

0.897

Q9UPU7

(UniProtKB/Swiss-Prot/P) Details

TBC1 domain family member 2B

Q5SZD1

Interaction Score

0.896

O94927

(UniProtKB/Swiss-Prot/P) Details

HAUS augmin-like complex subunit 5

Q5SZD1

Interaction Score

0.891

A0A087WYM5

(UniProtKB/TrEmbl/P) Details

Protein TALPID3

Q5SZD1

Interaction Score

0.891

Q6TV06

(UniProtKB/TrEmbl/P) Details

Breast cancer-associated antigen SGA-56M

Q5SZD1

Interaction Score

0.891

A0A0C4DH65

(UniProtKB/TrEmbl/P) Details

Protein KRBA1

Q5SZD1

Interaction Score

0.888

E9PD50

(UniProtKB/TrEmbl/P) Details

Protein SMG7

Q5SZD1

Interaction Score

0.887

P49642

(UniProtKB/Swiss-Prot/P) Details

DNA primase small subunit

Q5SZD1

Interaction Score

0.884

Q6PGR4

(UniProtKB/TrEmbl/P) Details

NCOR1 protein

Q5SZD1

Interaction Score

0.883

Q9BY89

(UniProtKB/Swiss-Prot/P) Details

Uncharacterized protein KIAA1671

Q5SZD1

Interaction Score

0.883

A6NF31

(UniProtKB/TrEmbl/P) Details

Oral-facial-digital syndrome 1 protein

Q5SZD1

Interaction Score

0.874

Q5VUJ6

(UniProtKB/Swiss-Prot/P) Details

Leucine-rich repeat and calponin homology domain-containing protein 2

Q5SZD1

Interaction Score

0.874

A0A0C4DFW9

(UniProtKB/TrEmbl/P) Details

Cellular tumor antigen p53

Q5SZD1

Interaction Score

0.864

Q6R327

(UniProtKB/Swiss-Prot/P) Details

Rapamycin-insensitive companion of mTOR

Q5SZD1

Interaction Score

0.855

Q7Z626

(UniProtKB/TrEmbl/P) Details

STIL protein

Q5SZD1

Interaction Score

0.85

Q9H019

(UniProtKB/Swiss-Prot/P) Details

Mitochondrial fission regulator 1-like

Q5SZD1

Interaction Score

0.85

A0A0A0MR87

(UniProtKB/TrEmbl/P) Details

SCL-interrupting locus protein

Q5SZD1

Interaction Score

0.847

Q6SPF0

(UniProtKB/Swiss-Prot/P) Details

Atherin

Q5SZD1

Interaction Score

0.785

O75665

(UniProtKB/Swiss-Prot/P) Details

Oral-facial-digital syndrome 1 protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cilium basal body (GO:0036064)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centriolar satellite (GO:0034451)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Centriole (GO:0005814)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cilium (GO:0005929)	0.86	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.86	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q5SZD1

Interaction Score

0.785

P15924

(UniProtKB/Swiss-Prot/P) Details

Desmoplakin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	0.3	Unknown: HDA	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Cornified envelope (GO:0001533)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intermediate filament (GO:0005882)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.96	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.96	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Experimental: experimental	Organelle	PubMed
Membrane	Basolateral plasma membrane (GO:0016323)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Fascia adherens (GO:0005916)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Intercalated disc (GO:0014704)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Desmosome (GO:0030057)	0.999	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q5SZD1

Interaction Score

0.752

Q59FT3

(UniProtKB/TrEmbl/P) Details

SATB family member 2 variant

Q5SZD1

Interaction Score

0.752

F5H0F9

(UniProtKB/TrEmbl/P) Details

Anaphase-promoting complex subunit 5

Q5SZD1

Interaction Score

0.7

Q9P2K8

(UniProtKB/Swiss-Prot/P) Details

eIF-2-alpha kinase GCN2

Q5SZD1

Interaction Score

0.699

Q8TCU4

(UniProtKB/Swiss-Prot/P) Details

Alstrom syndrome protein 1

Q5SZD1

Interaction Score

0.697

Q9NXB0

(UniProtKB/Swiss-Prot/P) Details

Meckel syndrome type 1 protein

Q5SZD1

Interaction Score

0.694

Q6ZRV2

(UniProtKB/Swiss-Prot/P) Details

Protein FAM83H

Q5SZD1

Interaction Score

0.694

O60573

(UniProtKB/Swiss-Prot/P) Details

Eukaryotic translation initiation factor 4E type 2

Q5SZD1

Interaction Score

0.691

P31321

(UniProtKB/Swiss-Prot/P) Details

cAMP-dependent protein kinase type I-beta regulatory subunit

Q5SZD1

Interaction Score

0.686

Q9Y6Y8

(UniProtKB/Swiss-Prot/P) Details

SEC23-interacting protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.98	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.98	Unknown: traceable author statement	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.98	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.98	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.999	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endoplasmic reticulum-Golgi intermediate compartment (GO:0005793)	0.999	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.999	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.999	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	ER to Golgi transport vesicle (GO:0030134)	0.999	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Secretory-pathway	ER to Golgi transport vesicle membrane (GO:0012507)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q5SZD1

Interaction Score

0.681

Q8IWZ3

(UniProtKB/Swiss-Prot/P) Details

Ankyrin repeat and KH domain-containing protein 1

Q5SZD1

Interaction Score

0.671

O43924

(UniProtKB/Swiss-Prot/P) Details

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta

Q5SZD1

Interaction Score

0.658

Q71RB4

(UniProtKB/TrEmbl/P) Details

PP2121

Q5SZD1

Interaction Score

0.658

A4D2J9

(UniProtKB/TrEmbl/P) Details

Calcium/calmodulin-dependent protein kinase (CaM kinase) II beta

Q5SZD1

Interaction Score

0.658

A0A0A0MRG9

(UniProtKB/TrEmbl/P) Details

CDK5 regulatory subunit-associated protein 2

Q5SZD1

Interaction Score

0.656

Q12815

(UniProtKB/Swiss-Prot/P) Details

Tastin

Q5SZD1

Interaction Score

0.637

Q59FE1

(UniProtKB/TrEmbl/P) Details

Eukaryotic translation initiation factor 4E member 2 variant

Q5SZD1

Interaction Score

0.637

Q7Z3M0

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein DKFZp686M1993

Q5SZD1

Interaction Score

0.56

E9PSF2

(UniProtKB/TrEmbl/P) Details

SCL-interrupting locus protein

Q5SZD1

Interaction Score

0.56

B8ZZ50

(UniProtKB/TrEmbl/P) Details

Eukaryotic translation initiation factor 4E type 2

Q5SZD1

Interaction Score

0.56

B8ZZL3

(UniProtKB/TrEmbl/P) Details

Eukaryotic translation initiation factor 4E type 2

Q5SZD1

Interaction Score

0.56

B9A023

(UniProtKB/TrEmbl/P) Details

Eukaryotic translation initiation factor 4E type 2

Q5SZD1

Interaction Score

0.56

D6R938

(UniProtKB/TrEmbl/P) Details

Calcium/calmodulin-dependent protein kinase (CaM kinase) II delta, isoform CRA_e

Q5SZD1

Interaction Score

0.56

E9PBG7

(UniProtKB/TrEmbl/P) Details

Calcium/calmodulin-dependent protein kinase type II subunit delta

Q5SZD1

Interaction Score

0.56

E9PF82

(UniProtKB/TrEmbl/P) Details

Calcium/calmodulin-dependent protein kinase type II subunit delta

Q5SZD1

Interaction Score

0.49

Q08AK7

(UniProtKB/TrEmbl/P) Details

Ubiquitin specific peptidase 4

Q5SZD1

Interaction Score

0.49

Q6IB24

(UniProtKB/TrEmbl/P) Details

PDE6D protein

Q5SZD1

Interaction Score

0.49

O14997

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein

Q5SZD1

Interaction Score

0.49

H0Y2S2

(UniProtKB/TrEmbl/P) Details

Meckel syndrome type 1 protein

Q5SZD1

Interaction Score

0.49

Q59H94

(UniProtKB/TrEmbl/P) Details

Gamma filamin variant

Q5SZD1

Interaction Score

0.49

Q53RG0

(UniProtKB/TrEmbl/P) Details

Eukaryotic translation initiation factor 4E member 2, isoform CRA_c

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Q5SZD1

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

Q5SZD1

P51587

Breast cancer type 2 susceptibility protein

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q5SZD1

Q9Y6D9

Mitotic spindle assembly checkpoint protein MAD1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q5SZD1

O75376

Nuclear receptor corepressor 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q5SZD1

Q9Y3I1

F-box only protein 7

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q5SZD1

Q92540

Protein SMG7

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q5SZD1

Q5VUA4

Zinc finger protein 318

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q5SZD1

Q7Z4H7

HAUS augmin-like complex subunit 6

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q5SZD1

O15379

Histone deacetylase 3

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q5SZD1

Q8NEZ3

WD repeat-containing protein 19

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q5SZD1

Q9UPR3

Protein SMG5

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q5SZD1

P56282

DNA polymerase epsilon subunit 2

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q5SZD1

Q9UJX4

Anaphase-promoting complex subunit 5

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q5SZD1