Q5VTR2

E3 ubiquitin-protein ligase BRE1A    //   UniProt Profile 

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Species

H. sapiens

Number of Interactions

129 / 168

Average Interaction Score

0.887

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Ubiquitin ligase complex (GO:0000151) 0.988 Experimental: inferred from direct assay GO PubMed 
Cytosol HULC complex (GO:0033503) 0.988 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.988 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleolus (GO:0005730) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

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Interactions

All Details

Q5VTR2

Interaction Score
1

P04637

(UniProtKB/Swiss-Prot/P) Details

Cellular tumor antigen p53

Q5VTR2

Interaction Score
1

Q9H410

(UniProtKB/Swiss-Prot/P) Details

Kinetochore-associated protein DSN1 homolog

Q5VTR2

Interaction Score
1

P63146

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin-conjugating enzyme E2 B

Q5VTR2

Interaction Score
1

O43542

(UniProtKB/Swiss-Prot/P) Details

DNA repair protein XRCC3

Q5VTR2

Interaction Score
1

P42858

(UniProtKB/Swiss-Prot/P) Details

Huntingtin

Q5VTR2

Interaction Score
1

Q09161

(UniProtKB/Swiss-Prot/P) Details

Nuclear cap-binding protein subunit 1

Q5VTR2

Interaction Score
1

P12004

(UniProtKB/Swiss-Prot/P) Details

Proliferating cell nuclear antigen

Q5VTR2

Interaction Score
1

P33778

(UniProtKB/Swiss-Prot/P) Details

Histone H2B type 1-B

Q5VTR2

Interaction Score
1

Q16778

(UniProtKB/Swiss-Prot/P) Details

Histone H2B type 2-E

Q5VTR2

Interaction Score
1

Q9HAU4

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase SMURF2

Q5VTR2

Interaction Score
1

P29084

(UniProtKB/Swiss-Prot/P) Details

Transcription initiation factor IIE subunit beta

Q5VTR2

Interaction Score
1

Q92905

(UniProtKB/Swiss-Prot/P) Details

COP9 signalosome complex subunit 5

Q5VTR2

Interaction Score
1

P62805

(UniProtKB/Swiss-Prot/P) Details

Histone H4

Q5VTR2

Interaction Score
1

P52597

(UniProtKB/Swiss-Prot/P) Details

Heterogeneous nuclear ribonucleoprotein F

Q5VTR2

Interaction Score
1

P22314

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin-like modifier-activating enzyme 1

Q5VTR2

Interaction Score
1

O75150

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase BRE1B

Q5VTR2

Interaction Score
1

Q7KZ85

(UniProtKB/Swiss-Prot/P) Details

Transcription elongation factor SPT6

Q5VTR2

Interaction Score
1

O96017

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein kinase Chk2

Q5VTR2

Interaction Score
1

Q9UQ80

(UniProtKB/Swiss-Prot/P) Details

Proliferation-associated protein 2G4

Q5VTR2

Interaction Score
1

P16104

(UniProtKB/Swiss-Prot/P) Details

Histone H2AX

Q5VTR2

Interaction Score
1

P10275

(UniProtKB/Swiss-Prot/P) Details

Androgen receptor

Q5VTR2

Interaction Score
1

Q13503

(UniProtKB/Swiss-Prot/P) Details

Mediator of RNA polymerase II transcription subunit 21

Q5VTR2

Interaction Score
1

Q06330

(UniProtKB/Swiss-Prot/P) Details

Recombining binding protein suppressor of hairless

Q5VTR2

Interaction Score
1

Q9Y5K5

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin carboxyl-terminal hydrolase isozyme L5

Q5VTR2

Interaction Score
1

Q8N6T7

(UniProtKB/Swiss-Prot/P) Details

NAD-dependent protein deacetylase sirtuin-6

Q5VTR2

Interaction Score
1

P50750

(UniProtKB/Swiss-Prot/P) Details

Cyclin-dependent kinase 9

Q5VTR2

Interaction Score
1

Q6P1J9

(UniProtKB/Swiss-Prot/P) Details

Parafibromin

Q5VTR2

Interaction Score
1

P49336

(UniProtKB/Swiss-Prot/P) Details

Cyclin-dependent kinase 8

Q5VTR2

Interaction Score
1

P49459

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin-conjugating enzyme E2 A

Q5VTR2

Interaction Score
1

Q8N1G2

(UniProtKB/Swiss-Prot/P) Details

Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1

Q5VTR2

Interaction Score
1

Q8N7H5

(UniProtKB/Swiss-Prot/P) Details

RNA polymerase II-associated factor 1 homolog

Q5VTR2

Interaction Score
1

Q9ULK4

(UniProtKB/Swiss-Prot/P) Details

Mediator of RNA polymerase II transcription subunit 23

Q5VTR2

Interaction Score
1

P27348

(UniProtKB/Swiss-Prot/P) Details

14-3-3 protein theta

Q5VTR2

Interaction Score
1

Q13315

(UniProtKB/Swiss-Prot/P) Details

Serine-protein kinase ATM

Q5VTR2

Interaction Score
1

Q9BV68

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase RNF126

Q5VTR2

Interaction Score
1

P54277

(UniProtKB/Swiss-Prot/P) Details

PMS1 protein homolog 1

Q5VTR2

Interaction Score
1

Q99598

(UniProtKB/Swiss-Prot/P) Details

Translin-associated protein X

Q5VTR2

Interaction Score
1

Q9Y5B9

(UniProtKB/Swiss-Prot/P) Details

FACT complex subunit SPT16

Q5VTR2

Interaction Score
1

P42772

(UniProtKB/Swiss-Prot/P) Details

Cyclin-dependent kinase 4 inhibitor B

Q5VTR2

Interaction Score
1

P23396

(UniProtKB/Swiss-Prot/P) Details

40S ribosomal protein S3

Q5VTR2

Interaction Score
1

P68036

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin-conjugating enzyme E2 L3

Q5VTR2

Interaction Score
1

Q8TD55

(UniProtKB/Swiss-Prot/P) Details

Pleckstrin homology domain-containing family O member 2

Q5VTR2

Interaction Score
1

P51965

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin-conjugating enzyme E2 E1

Q5VTR2

Interaction Score
1

Q9BTA9

(UniProtKB/Swiss-Prot/P) Details

WW domain-containing adapter protein with coiled-coil

Q5VTR2

Interaction Score
1

O95721

(UniProtKB/Swiss-Prot/P) Details

Synaptosomal-associated protein 29

Q5VTR2

Interaction Score
0.999

Q9H3U1

(UniProtKB/Swiss-Prot/P) Details

Protein unc-45 homolog A

Q5VTR2

Interaction Score
0.999

Q8TDY2

(UniProtKB/Swiss-Prot/P) Details

RB1-inducible coiled-coil protein 1

Q5VTR2

Interaction Score
0.999

P54368

(UniProtKB/Swiss-Prot/P) Details

Ornithine decarboxylase antizyme 1

Q5VTR2

Interaction Score
0.999

Q15018

(UniProtKB/Swiss-Prot/P) Details

BRISC complex subunit Abraxas 2

Q5VTR2

Interaction Score
0.999

P0CG47

(UniProtKB/Swiss-Prot/P) Details

Polyubiquitin-B

Q5VTR2

Interaction Score
0.999

Q68DK7

(UniProtKB/Swiss-Prot/P) Details

Male-specific lethal 1 homolog

Q5VTR2

Interaction Score
0.999

P51665

(UniProtKB/Swiss-Prot/P) Details

26S proteasome non-ATPase regulatory subunit 7

Q5VTR2

Interaction Score
0.999

Q9NX04

(UniProtKB/Swiss-Prot/P) Details

Uncharacterized protein C1orf109

Q5VTR2

Interaction Score
0.999

Q6FI81

(UniProtKB/Swiss-Prot/P) Details

Anamorsin

Q5VTR2

Interaction Score
0.999

Q6PCT2

(UniProtKB/Swiss-Prot/P) Details

F-box/LRR-repeat protein 19

Q5VTR2

Interaction Score
0.999

O00487

(UniProtKB/Swiss-Prot/P) Details

26S proteasome non-ATPase regulatory subunit 14

Q5VTR2

Interaction Score
0.998

Q16777

(UniProtKB/Swiss-Prot/P) Details

Histone H2A type 2-C

Q5VTR2

Interaction Score
0.998

P0CG48

(UniProtKB/Swiss-Prot/P) Details

Polyubiquitin-C

Q5VTR2

Interaction Score
0.998

P06753

(UniProtKB/Swiss-Prot/P) Details

Tropomyosin alpha-3 chain

Q5VTR2

Interaction Score
0.998

Q6P1M3

(UniProtKB/Swiss-Prot/P) Details

Lethal(2) giant larvae protein homolog 2

Q5VTR2

Interaction Score
0.998

Q9Y4E8

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin carboxyl-terminal hydrolase 15

Q5VTR2

Interaction Score
0.997

Q9HCI7

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase MSL2

Q5VTR2

Interaction Score
0.997

Q9BWF2

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase TRAIP

Q5VTR2

Interaction Score
0.997

O95429

(UniProtKB/Swiss-Prot/P) Details

BAG family molecular chaperone regulator 4

Q5VTR2

Interaction Score
0.996

O95793

(UniProtKB/Swiss-Prot/P) Details

Double-stranded RNA-binding protein Staufen homolog 1

Q5VTR2

Interaction Score
0.996

Q9P270

(UniProtKB/Swiss-Prot/P) Details

SLAIN motif-containing protein 2

Q5VTR2

Interaction Score
0.996

Q9NZM3

(UniProtKB/Swiss-Prot/P) Details

Intersectin-2

Q5VTR2

Interaction Score
0.996

Q9NQW7

(UniProtKB/Swiss-Prot/P) Details

Xaa-Pro aminopeptidase 1

Q5VTR2

Interaction Score
0.994

Q71DI3

(UniProtKB/Swiss-Prot/P) Details

Histone H3.2

Q5VTR2

Interaction Score
0.993

Q9Y3C0

(UniProtKB/Swiss-Prot/P) Details

WASH complex subunit 3

Q5VTR2

Interaction Score
0.991

Q6FI13

(UniProtKB/Swiss-Prot/P) Details

Histone H2A type 2-A

Q5VTR2

Interaction Score
0.99

A0A0D9SG71

(UniProtKB/TrEmbl/P) Details

Ubiquitin-conjugating enzyme E2 A

Q5VTR2

Interaction Score
0.989

Q9BTM9

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin-related modifier 1

Q5VTR2

Interaction Score
0.988

P52732

(UniProtKB/Swiss-Prot/P) Details

Kinesin-like protein KIF11

Q5VTR2

Interaction Score
0.988

Q9Y6A5

(UniProtKB/Swiss-Prot/P) Details

Transforming acidic coiled-coil-containing protein 3

Q5VTR2

Interaction Score
0.988

P33176

(UniProtKB/Swiss-Prot/P) Details

Kinesin-1 heavy chain

Q5VTR2

Interaction Score
0.988

Q5XG96

(UniProtKB/TrEmbl/P) Details

PMS1 protein homolog 1

Q5VTR2

Interaction Score
0.988

Q12965

(UniProtKB/Swiss-Prot/P) Details

Unconventional myosin-Ie

Q5VTR2

Interaction Score
0.987

P04062

(UniProtKB/Swiss-Prot/P) Details

Glucosylceramidase

Q5VTR2

Interaction Score
0.987

Q53GA5

(UniProtKB/TrEmbl/P) Details

Cellular tumor antigen p53

Q5VTR2

Interaction Score
0.986

Q8IUH5

(UniProtKB/Swiss-Prot/P) Details

Palmitoyltransferase ZDHHC17

Q5VTR2

Interaction Score
0.98

Q9Y2J4

(UniProtKB/Swiss-Prot/P) Details

Angiomotin-like protein 2

Q5VTR2

Interaction Score
0.979

Q5T6H7

(UniProtKB/TrEmbl/P) Details

Xaa-Pro aminopeptidase 1

Q5VTR2

Interaction Score
0.972

Q8N6Y0

(UniProtKB/Swiss-Prot/P) Details

Usher syndrome type-1C protein-binding protein 1

Q5VTR2

Interaction Score
0.97

Q9BXU3

(UniProtKB/Swiss-Prot/P) Details

Testis-expressed protein 13A

Q5VTR2

Interaction Score
0.966

P04629

(UniProtKB/Swiss-Prot/P) Details

High affinity nerve growth factor receptor

Q5VTR2

Interaction Score
0.96

B7ZAA0

(UniProtKB/TrEmbl/P) Details

cDNA, FLJ79114, highly similar to PMS1 protein homolog 1

Q5VTR2

Interaction Score
0.96

E9PC40

(UniProtKB/TrEmbl/P) Details

PMS1 protein homolog 1

Q5VTR2

Interaction Score
0.96

Q3BDU3

(UniProtKB/TrEmbl/P) Details

PMS1 protein homolog 1

Q5VTR2

Interaction Score
0.958

Q96DE7

(UniProtKB/TrEmbl/P) Details

SMURF2 protein

Q5VTR2

Interaction Score
0.958

A0PJJ0

(UniProtKB/TrEmbl/P) Details

LLGL2 protein

Q5VTR2

Interaction Score
0.948

J3QRV5

(UniProtKB/TrEmbl/P) Details

Lethal(2) giant larvae protein homolog 2

Q5VTR2

Interaction Score
0.948

J3QQY4

(UniProtKB/TrEmbl/P) Details

Ornithine decarboxylase antizyme 1

Q5VTR2

Interaction Score
0.948

A0A087WWU8

(UniProtKB/TrEmbl/P) Details

Tropomyosin alpha-3 chain

Q5VTR2

Interaction Score
0.94

Q8TDR4

(UniProtKB/Swiss-Prot/P) Details

T-complex protein 10A homolog 1

Q5VTR2

Interaction Score
0.938

Q9Y2V7

(UniProtKB/Swiss-Prot/P) Details

Conserved oligomeric Golgi complex subunit 6

Q5VTR2

Interaction Score
0.937

Q5VYV7

(UniProtKB/Swiss-Prot/P) Details

Protein SLX4IP

Q5VTR2

Interaction Score
0.937

Q6PJX3

(UniProtKB/TrEmbl/P) Details

STAU1 protein

Q5VTR2

Interaction Score
0.91

Q9NUA2

(UniProtKB/TrEmbl/P) Details

Androgen receptor

Q5VTR2

Interaction Score
0.907

Q8N8Y1

(UniProtKB/TrEmbl/P) Details

Usher syndrome 1C binding protein 1, isoform CRA_a

Q5VTR2

Interaction Score
0.907

Q96IX9

(UniProtKB/Swiss-Prot/P) Details

Putative ankyrin repeat domain-containing protein 26-like 1

Q5VTR2

Interaction Score
0.899

Q6P164

(UniProtKB/TrEmbl/P) Details

Kinesin-like protein

Q5VTR2

Interaction Score
0.85

Q9NRW1

(UniProtKB/Swiss-Prot/P) Details

Ras-related protein Rab-6B

Q5VTR2

Interaction Score
0.8

A0A087WT22

(UniProtKB/TrEmbl/P) Details

Cellular tumor antigen p53

Q5VTR2

Interaction Score
0.8

A0A087WXZ1

(UniProtKB/TrEmbl/P) Details

Cellular tumor antigen p53

Q5VTR2

Interaction Score
0.8

A0A087X1Q1

(UniProtKB/TrEmbl/P) Details

Cellular tumor antigen p53

Q5VTR2

Interaction Score
0.8

B7Z306

(UniProtKB/TrEmbl/P) Details

cDNA FLJ52264, highly similar to Ubiquitin-conjugating enzyme E2 E1

Q5VTR2

Interaction Score
0.8

J3KSZ8

(UniProtKB/TrEmbl/P) Details

Male-specific lethal 1 homolog

Q5VTR2

Interaction Score
0.8

M0QXA0

(UniProtKB/TrEmbl/P) Details

NAD-dependent protein deacetylase sirtuin-6

Q5VTR2

Interaction Score
0.8

M0R1N9

(UniProtKB/TrEmbl/P) Details

NAD-dependent protein deacetylase sirtuin-6

Q5VTR2

Interaction Score
0.8

Q53XC8

(UniProtKB/TrEmbl/P) Details

Full-length cDNA clone CS0DC014YE11 of Neuroblastoma of Homo sapiens

Q5VTR2

Interaction Score
0.8

Q05DL5

(UniProtKB/TrEmbl/P) Details

MED23 protein

Q5VTR2

Interaction Score
0.79

F5GWI9

(UniProtKB/TrEmbl/P) Details

WASH complex subunit 3

Q5VTR2

Interaction Score
0.79

F5GZ97

(UniProtKB/TrEmbl/P) Details

WASH complex subunit 3

Q5VTR2

Interaction Score
0.79

H3BVB1

(UniProtKB/TrEmbl/P) Details

F-box/LRR-repeat protein 19

Q5VTR2

Interaction Score
0.781

Q96PB7

(UniProtKB/Swiss-Prot/P) Details

Noelin-3

Q5VTR2

Interaction Score
0.7

Q6ZSG2

(UniProtKB/Swiss-Prot/P) Details

Protein FAM196A

Q5VTR2

Interaction Score
0.692

Q4KMR3

(UniProtKB/TrEmbl/P) Details

MYO1E variant protein

Q5VTR2

Interaction Score
0.692

Q9UHA7

(UniProtKB/Swiss-Prot/P) Details

Interleukin-36 alpha

Q5VTR2

Interaction Score
0.504

Q8NBS9

(UniProtKB/Swiss-Prot/P) Details

Thioredoxin domain-containing protein 5

Q5VTR2

Interaction Score
0

A0A087WUX9

(UniProtKB/TrEmbl/P) Details

Androgen receptor

Q5VTR2

Interaction Score
0

Q59F99

(UniProtKB/TrEmbl/P) Details

Staufen isoform b variant

Q5VTR2

Interaction Score
0

H3BT65

(UniProtKB/TrEmbl/P) Details

Anamorsin

Q5VTR2

Interaction Score
0

X5DR71

(UniProtKB/TrEmbl/P) Details

Tyrosine-protein kinase receptor

Q5VTR2

Interaction Score
0

B4DVP5

(UniProtKB/TrEmbl/P) Details

Fibroblast growth factor receptor

Q5VTR2

Interaction Score
0

J3KPQ0

(UniProtKB/TrEmbl/P) Details

Fibroblast growth factor receptor

Q5VTR2

Interaction Score
0

P22455

(UniProtKB/Swiss-Prot/P) Details

Fibroblast growth factor receptor 4

Q5VTR2

Interaction Score
0

A0A068F658

(UniProtKB/TrEmbl/P) Details

Glucosylceramidase

Q5VTR2

Interaction Score
0

Q6IMJ0

(UniProtKB/TrEmbl/P) Details

NOELIN3_V2

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ComPPI is published in Nucleic Acids Research Database Issue 2015