Q7KZ85

Transcription elongation factor SPT6    //   UniProt Profile 

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Species

H. sapiens

Number of Interactions

112 / 153

Average Interaction Score

0.935

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.94 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytosol (GO:0005829) 0.94 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Unknown: non-traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Unknown: traceable author statement GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Transcription elongation factor complex (GO:0008023) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus Transcriptionally active chromatin (GO:0035327) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

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Interactions

All Details

Q7KZ85

Interaction Score
1

P50402

(UniProtKB/Swiss-Prot/P) Details

Emerin

Q7KZ85

Interaction Score
1

P03372

(UniProtKB/Swiss-Prot/P) Details

Estrogen receptor

Q7KZ85

Interaction Score
1

P55072

(UniProtKB/Swiss-Prot/P) Details

Transitional endoplasmic reticulum ATPase

Q7KZ85

Interaction Score
1

P38398

(UniProtKB/Swiss-Prot/P) Details

Breast cancer type 1 susceptibility protein

Q7KZ85

Interaction Score
1

P35226

(UniProtKB/Swiss-Prot/P) Details

Polycomb complex protein BMI-1

Q7KZ85

Interaction Score
1

Q01780

(UniProtKB/Swiss-Prot/P) Details

Exosome component 10

Q7KZ85

Interaction Score
1

P04637

(UniProtKB/Swiss-Prot/P) Details

Cellular tumor antigen p53

Q7KZ85

Interaction Score
1

O94763

(UniProtKB/Swiss-Prot/P) Details

Unconventional prefoldin RPB5 interactor 1

Q7KZ85

Interaction Score
1

Q15796

(UniProtKB/Swiss-Prot/P) Details

Mothers against decapentaplegic homolog 2

Q7KZ85

Interaction Score
1

P19387

(UniProtKB/Swiss-Prot/P) Details

DNA-directed RNA polymerase II subunit RPB3

Q7KZ85

Interaction Score
1

Q5FBB7

(UniProtKB/Swiss-Prot/P) Details

Shugoshin 1

Q7KZ85

Interaction Score
1

P62136

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

Q7KZ85

Interaction Score
1

P14866

(UniProtKB/Swiss-Prot/P) Details

Heterogeneous nuclear ribonucleoprotein L

Q7KZ85

Interaction Score
1

P19338

(UniProtKB/Swiss-Prot/P) Details

Nucleolin

Q7KZ85

Interaction Score
1

O75150

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase BRE1B

Q7KZ85

Interaction Score
1

P29692

(UniProtKB/Swiss-Prot/P) Details

Elongation factor 1-delta

Q7KZ85

Interaction Score
1

P38936

(UniProtKB/Swiss-Prot/P) Details

Cyclin-dependent kinase inhibitor 1

Q7KZ85

Interaction Score
1

Q13469

(UniProtKB/Swiss-Prot/P) Details

Nuclear factor of activated T-cells, cytoplasmic 2

Q7KZ85

Interaction Score
1

P68400

(UniProtKB/Swiss-Prot/P) Details

Casein kinase II subunit alpha

Q7KZ85

Interaction Score
1

P16104

(UniProtKB/Swiss-Prot/P) Details

Histone H2AX

Q7KZ85

Interaction Score
1

Q5VTR2

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase BRE1A

Q7KZ85

Interaction Score
1

O75530

(UniProtKB/Swiss-Prot/P) Details

Polycomb protein EED

Q7KZ85

Interaction Score
1

P45973

(UniProtKB/Swiss-Prot/P) Details

Chromobox protein homolog 5

Q7KZ85

Interaction Score
1

Q92466

(UniProtKB/Swiss-Prot/P) Details

DNA damage-binding protein 2

Q7KZ85

Interaction Score
1

Q14258

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin/ISG15 ligase TRIM25

Q7KZ85

Interaction Score
1

P01100

(UniProtKB/Swiss-Prot/P) Details

Proto-oncogene c-Fos

Q7KZ85

Interaction Score
1

Q9NRC8

(UniProtKB/Swiss-Prot/P) Details

NAD-dependent protein deacetylase sirtuin-7

Q7KZ85

Interaction Score
1

Q14676

(UniProtKB/Swiss-Prot/P) Details

Mediator of DNA damage checkpoint protein 1

Q7KZ85

Interaction Score
1

P42166

(UniProtKB/Swiss-Prot/P) Details

Lamina-associated polypeptide 2, isoform alpha

Q7KZ85

Interaction Score
1

Q9NVU0

(UniProtKB/Swiss-Prot/P) Details

DNA-directed RNA polymerase III subunit RPC5

Q7KZ85

Interaction Score
1

O75190

(UniProtKB/Swiss-Prot/P) Details

DnaJ homolog subfamily B member 6

Q7KZ85

Interaction Score
1

O95602

(UniProtKB/Swiss-Prot/P) Details

DNA-directed RNA polymerase I subunit RPA1

Q7KZ85

Interaction Score
1

Q14690

(UniProtKB/Swiss-Prot/P) Details

Protein RRP5 homolog

Q7KZ85

Interaction Score
1

Q9NQG5

(UniProtKB/Swiss-Prot/P) Details

Regulation of nuclear pre-mRNA domain-containing protein 1B

Q7KZ85

Interaction Score
1

P19388

(UniProtKB/Swiss-Prot/P) Details

DNA-directed RNA polymerases I, II, and III subunit RPABC1

Q7KZ85

Interaction Score
1

P24928

(UniProtKB/Swiss-Prot/P) Details

DNA-directed RNA polymerase II subunit RPB1

Q7KZ85

Interaction Score
1

P68431

(UniProtKB/Swiss-Prot/P) Details

Histone H3.1

Q7KZ85

Interaction Score
1

O00267

(UniProtKB/Swiss-Prot/P) Details

Transcription elongation factor SPT5

Q7KZ85

Interaction Score
1

P23193

(UniProtKB/Swiss-Prot/P) Details

Transcription elongation factor A protein 1

Q7KZ85

Interaction Score
1

Q9UJX3

(UniProtKB/Swiss-Prot/P) Details

Anaphase-promoting complex subunit 7

Q7KZ85

Interaction Score
1

Q9BV73

(UniProtKB/Swiss-Prot/P) Details

Centrosome-associated protein CEP250

Q7KZ85

Interaction Score
1

O75496

(UniProtKB/Swiss-Prot/P) Details

Geminin

Q7KZ85

Interaction Score
1

Q6PD62

(UniProtKB/Swiss-Prot/P) Details

RNA polymerase-associated protein CTR9 homolog

Q7KZ85

Interaction Score
1

P63272

(UniProtKB/Swiss-Prot/P) Details

Transcription elongation factor SPT4

Q7KZ85

Interaction Score
1

P23258

(UniProtKB/Swiss-Prot/P) Details

Tubulin gamma-1 chain

Q7KZ85

Interaction Score
1

Q08945

(UniProtKB/Swiss-Prot/P) Details

FACT complex subunit SSRP1

Q7KZ85

Interaction Score
1

P25791

(UniProtKB/Swiss-Prot/P) Details

Rhombotin-2

Q7KZ85

Interaction Score
1

Q86XR8

(UniProtKB/Swiss-Prot/P) Details

Centrosomal protein of 57 kDa

Q7KZ85

Interaction Score
0.999

Q86WV1

(UniProtKB/Swiss-Prot/P) Details

Src kinase-associated phosphoprotein 1

Q7KZ85

Interaction Score
0.999

Q96ST2

(UniProtKB/Swiss-Prot/P) Details

Protein IWS1 homolog

Q7KZ85

Interaction Score
0.999

Q92731

(UniProtKB/Swiss-Prot/P) Details

Estrogen receptor beta

Q7KZ85

Interaction Score
0.999

P0CAP2

(UniProtKB/Swiss-Prot/P) Details

DNA-directed RNA polymerase II subunit GRINL1A

Q7KZ85

Interaction Score
0.999

Q9Y3F4

(UniProtKB/Swiss-Prot/P) Details

Serine-threonine kinase receptor-associated protein

Q7KZ85

Interaction Score
0.999

Q96EY4

(UniProtKB/Swiss-Prot/P) Details

Translation machinery-associated protein 16

Q7KZ85

Interaction Score
0.999

Q8WUA7

(UniProtKB/Swiss-Prot/P) Details

TBC1 domain family member 22A

Q7KZ85

Interaction Score
0.999

Q6EEV4

(UniProtKB/Swiss-Prot/P) Details

DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5

Q7KZ85

Interaction Score
0.999

Q9BRP4

(UniProtKB/Swiss-Prot/P) Details

Proteasomal ATPase-associated factor 1

Q7KZ85

Interaction Score
0.999

P42167

(UniProtKB/Swiss-Prot/P) Details

Lamina-associated polypeptide 2, isoforms beta/gamma

Q7KZ85

Interaction Score
0.999

P63104

(UniProtKB/Swiss-Prot/P) Details

14-3-3 protein zeta/delta

Q7KZ85

Interaction Score
0.998

P04626

(UniProtKB/Swiss-Prot/P) Details

Receptor tyrosine-protein kinase erbB-2

Q7KZ85

Interaction Score
0.998

Q9UBK9

(UniProtKB/Swiss-Prot/P) Details

Protein UXT

Q7KZ85

Interaction Score
0.998

Q9NWS0

(UniProtKB/Swiss-Prot/P) Details

PIH1 domain-containing protein 1

Q7KZ85

Interaction Score
0.997

O14730

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein kinase RIO3

Q7KZ85

Interaction Score
0.994

O75147

(UniProtKB/Swiss-Prot/P) Details

Obscurin-like protein 1

Q7KZ85

Interaction Score
0.993

A0A0A0MRY0

(UniProtKB/TrEmbl/P) Details

TBC1 domain family member 22A

Q7KZ85

Interaction Score
0.993

Q8TAF3

(UniProtKB/Swiss-Prot/P) Details

WD repeat-containing protein 48

Q7KZ85

Interaction Score
0.991

P0CAP1

(UniProtKB/Swiss-Prot/P) Details

Myocardial zonula adherens protein

Q7KZ85

Interaction Score
0.988

Q9NVX0

(UniProtKB/Swiss-Prot/P) Details

HAUS augmin-like complex subunit 2

Q7KZ85

Interaction Score
0.988

Q9UHV9

(UniProtKB/Swiss-Prot/P) Details

Prefoldin subunit 2

Q7KZ85

Interaction Score
0.987

Q9NY26

(UniProtKB/Swiss-Prot/P) Details

Zinc transporter ZIP1

Q7KZ85

Interaction Score
0.987

Q8TAP6

(UniProtKB/Swiss-Prot/P) Details

Centrosomal protein of 76 kDa

Q7KZ85

Interaction Score
0.985

Q53GA5

(UniProtKB/TrEmbl/P) Details

Cellular tumor antigen p53

Q7KZ85

Interaction Score
0.985

B4E1Q4

(UniProtKB/TrEmbl/P) Details

Serine/threonine-protein kinase RIO3

Q7KZ85

Interaction Score
0.983

P60903

(UniProtKB/Swiss-Prot/P) Details

Protein S100-A10

Q7KZ85

Interaction Score
0.982

Q14999

(UniProtKB/Swiss-Prot/P) Details

Cullin-7

Q7KZ85

Interaction Score
0.98

H3BP16

(UniProtKB/TrEmbl/P) Details

HAUS augmin-like complex subunit 2

Q7KZ85

Interaction Score
0.979

Q9UBT1

(UniProtKB/TrEmbl/P) Details

Estrogen receptor

Q7KZ85

Interaction Score
0.979

Q6DKI7

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein PVRIG

Q7KZ85

Interaction Score
0.978

Q13480

(UniProtKB/Swiss-Prot/P) Details

GRB2-associated-binding protein 1

Q7KZ85

Interaction Score
0.978

B0QYI1

(UniProtKB/TrEmbl/P) Details

TBC1 domain family member 22A

Q7KZ85

Interaction Score
0.973

P57775

(UniProtKB/Swiss-Prot/P) Details

F-box/WD repeat-containing protein 4

Q7KZ85

Interaction Score
0.958

P61758

(UniProtKB/Swiss-Prot/P) Details

Prefoldin subunit 3

Q7KZ85

Interaction Score
0.954

Q96CW5

(UniProtKB/Swiss-Prot/P) Details

Gamma-tubulin complex component 3

Q7KZ85

Interaction Score
0.95

F5H0C4

(UniProtKB/TrEmbl/P) Details

Proteasomal ATPase-associated factor 1

Q7KZ85

Interaction Score
0.95

H0Y4W6

(UniProtKB/TrEmbl/P) Details

Estrogen receptor

Q7KZ85

Interaction Score
0.946

Q8NEM0

(UniProtKB/Swiss-Prot/P) Details

Microcephalin

Q7KZ85

Interaction Score
0.934

O15121

(UniProtKB/Swiss-Prot/P) Details

Sphingolipid delta(4)-desaturase DES1

Q7KZ85

Interaction Score
0.923

Q9NYS7

(UniProtKB/Swiss-Prot/P) Details

WD repeat and SOCS box-containing protein 2

Q7KZ85

Interaction Score
0.912

G5E972

(UniProtKB/TrEmbl/P) Details

Lamina-associated polypeptide 2, isoforms beta/gamma

Q7KZ85

Interaction Score
0.911

F5H1T4

(UniProtKB/TrEmbl/P) Details

Receptor tyrosine-protein kinase erbB-2

Q7KZ85

Interaction Score
0.911

J3QLU9

(UniProtKB/TrEmbl/P) Details

Receptor protein-tyrosine kinase

Q7KZ85

Interaction Score
0.91

Q9BZD3

(UniProtKB/Swiss-Prot/P) Details

Putative GRINL1B complex locus protein 2

Q7KZ85

Interaction Score
0.905

Q6DD88

(UniProtKB/Swiss-Prot/P) Details

Atlastin-3

Q7KZ85

Interaction Score
0.902

B4DWR3

(UniProtKB/TrEmbl/P) Details

Prefoldin subunit 3

Q7KZ85

Interaction Score
0.897

Q9H8B3

(UniProtKB/TrEmbl/P) Details

cDNA FLJ13792 fis, clone THYRO1000072, weakly similar to MYOSIN LIGHT CHAIN KINASE, SMOOTH MUSCLE AND NON-MUSCLE ISOZYMES

Q7KZ85

Interaction Score
0.855

Q6FH24

(UniProtKB/TrEmbl/P) Details

Prefoldin subunit 3

Q7KZ85

Interaction Score
0.8

Q6FGR6

(UniProtKB/TrEmbl/P) Details

HCG2025883, isoform CRA_b

Q7KZ85

Interaction Score
0.8

A0A087WT22

(UniProtKB/TrEmbl/P) Details

Cellular tumor antigen p53

Q7KZ85

Interaction Score
0.8

A0A087WXZ1

(UniProtKB/TrEmbl/P) Details

Cellular tumor antigen p53

Q7KZ85

Interaction Score
0.8

A0A087X1Q1

(UniProtKB/TrEmbl/P) Details

Cellular tumor antigen p53

Q7KZ85

Interaction Score
0.8

E9PJK2

(UniProtKB/TrEmbl/P) Details

Polycomb protein EED

Q7KZ85

Interaction Score
0.8

A0A0C4DH01

(UniProtKB/TrEmbl/P) Details

DNA-directed RNA polymerase III subunit RPC5

Q7KZ85

Interaction Score
0.7

A1Z5I9

(UniProtKB/TrEmbl/P) Details

Mediator of DNA damage checkpoint 1 variant 1

Q7KZ85

Interaction Score
0.7

Q6NTA2

(UniProtKB/TrEmbl/P) Details

HNRNPL protein

Q7KZ85

Interaction Score
0.658

Q8NA56

(UniProtKB/Swiss-Prot/P) Details

Tetratricopeptide repeat protein 29

Q7KZ85

Interaction Score
0.658

Q8TC83

(UniProtKB/TrEmbl/P) Details

TTC29 protein

Q7KZ85

Interaction Score
0.658

Q4KMX6

(UniProtKB/TrEmbl/P) Details

ANAPC7 protein

Q7KZ85

Interaction Score
0.658

Q69YV3

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein DKFZp762H177

Q7KZ85

Interaction Score
0.56

Q59G12

(UniProtKB/TrEmbl/P) Details

Lamina-associated polypeptide 2, isoforms beta/gamma variant

Q7KZ85

Interaction Score
0.56

F5H6I7

(UniProtKB/TrEmbl/P) Details

Atlastin-3

Q7KZ85

Interaction Score
0.282

A0A0A0MTL8

(UniProtKB/TrEmbl/P) Details

Zinc transporter ZIP1

Q7KZ85

Interaction Score
0

X5DNK3

(UniProtKB/TrEmbl/P) Details

Receptor protein-tyrosine kinase

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ComPPI is published in Nucleic Acids Research Database Issue 2015