Q86XD5

Protein FAM131B // UniProt Profile

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Species	H. sapiens
Number of Interactions	48 / 57
Average Interaction Score	0.755

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.988	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	0.988	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

Q86XD5

Interaction Score

P53350

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein kinase PLK1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Midbody (GO:0030496)	0.8	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Spindle (GO:0005819)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Spindle midzone (GO:0051233)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Spindle microtubule (GO:0005876)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Spindle pole (GO:0000922)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Centriolar satellite (GO:0034451)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Centriole (GO:0005814)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Condensed nuclear chromosome outer kinetochore (GO:0000942)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Synaptonemal complex (GO:0000795)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Chromatin (GO:0000785)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Kinetochore (GO:0000776)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q86XD5

Interaction Score

O14965

(UniProtKB/Swiss-Prot/P) Details

Aurora kinase A

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Midbody (GO:0030496)	0.657	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Pronucleus (GO:0045120)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Female germ germinal vesicle (GO:0042585)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Spindle (GO:0005819)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Meiotic spindle (GO:0072687)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Spindle midzone (GO:0051233)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Spindle microtubule (GO:0005876)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Mitotic spindle pole (GO:0097431)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Spindle pole centrosome (GO:0031616)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Chromosome passenger complex (GO:0032133)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Centriole (GO:0005814)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Condensed nuclear chromosome, centromeric region (GO:0000780)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Axon hillock (GO:0043203)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Cilium (GO:0005929)	0.657	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q86XD5

Interaction Score

0.999

Q99741

(UniProtKB/Swiss-Prot/P) Details

Cell division control protein 6 homolog

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Spindle midzone (GO:0051233)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Spindle pole (GO:0000922)	0.999	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Intercellular bridge (GO:0045171)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q86XD5

Interaction Score

0.999

Q9UNY4

(UniProtKB/Swiss-Prot/P) Details

Transcription termination factor 2

Q86XD5

Interaction Score

0.999

Q93050

(UniProtKB/Swiss-Prot/P) Details

V-type proton ATPase 116 kDa subunit a isoform 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear speck (GO:0016607)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.99	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.99	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endosome membrane (GO:0010008)	0.99	Unknown: traceable author statement	GO	PubMed
Cytosol	Vacuolar proton-transporting V-type ATPase complex (GO:0016471)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Vacuolar proton-transporting V-type ATPase, V0 domain (GO:0000220)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Lysosomal membrane (GO:0005765)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Phagocytic vesicle membrane (GO:0030670)	0.99	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Melanosome (GO:0042470)	0.99	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Secretory granule membrane (GO:0030667)	0.99	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.987	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.987	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.987	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.987	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q86XD5

Interaction Score

0.998

P11388

(UniProtKB/Swiss-Prot/P) Details

DNA topoisomerase 2-alpha

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	DNA topoisomerase complex (ATP-hydrolyzing) (GO:0009330)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Viral integration complex (GO:0019035)	1	Unknown: non-traceable author statement	GO	PubMed
Cytosol	Centriole (GO:0005814)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear chromosome (GO:0000228)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Condensed chromosome (GO:0000793)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q86XD5

Interaction Score

0.998

Q15788

(UniProtKB/Swiss-Prot/P) Details

Nuclear receptor coactivator 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.96	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Nucleus	Nuclear chromatin (GO:0000790)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q86XD5

Interaction Score

0.996

Q13459

(UniProtKB/Swiss-Prot/P) Details

Unconventional myosin-IXb

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cell cortex (GO:0005938)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Myosin complex (GO:0016459)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Actin filament (GO:0005884)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q86XD5

Interaction Score

0.996

Q9Y6D5

(UniProtKB/Swiss-Prot/P) Details

Brefeldin A-inhibited guanine nucleotide-exchange protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Endomembrane system (GO:0012505)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.999	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Trans-Golgi network (GO:0005802)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Recycling endosome (GO:0055037)	0.999	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Axonemal microtubule (GO:0005879)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Dendritic spine (GO:0043197)	0.996	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.996	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Symmetric synapse (GO:0032280)	0.996	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Asymmetric synapse (GO:0032279)	0.996	Predicted: inferred from sequence or structural similarity	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q86XD5

Interaction Score

0.995

Q9UK61

(UniProtKB/Swiss-Prot/P) Details

Protein TASOR

Q86XD5

Interaction Score

0.993

Q96EE3

(UniProtKB/Swiss-Prot/P) Details

Nucleoporin SEH1

Q86XD5

Interaction Score

0.991

Q9BSJ5

(UniProtKB/Swiss-Prot/P) Details

Uncharacterized protein C17orf80

Q86XD5

Interaction Score

0.99

Q8WVD2

(UniProtKB/TrEmbl/P) Details

MYO9B protein

Q86XD5

Interaction Score

0.989

Q6BDS2

(UniProtKB/Swiss-Prot/P) Details

UHRF1-binding protein 1

Q86XD5

Interaction Score

0.988

I3L072

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein C17orf80

Q86XD5

Interaction Score

0.988

Q96AP0

(UniProtKB/Swiss-Prot/P) Details

Adrenocortical dysplasia protein homolog

Q86XD5

Interaction Score

0.987

Q6IBW4

(UniProtKB/Swiss-Prot/P) Details

Condensin-2 complex subunit H2

Q86XD5

Interaction Score

0.984

O15228

(UniProtKB/Swiss-Prot/P) Details

Dihydroxyacetone phosphate acyltransferase

Q86XD5

Interaction Score

0.983

Q68D91

(UniProtKB/Swiss-Prot/P) Details

Metallo-beta-lactamase domain-containing protein 2

Q86XD5

Interaction Score

0.982

P49356

(UniProtKB/Swiss-Prot/P) Details

Protein farnesyltransferase subunit beta

Q86XD5

Interaction Score

0.963

P12236

(UniProtKB/Swiss-Prot/P) Details

ADP/ATP translocase 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Experimental: experimental	Organelle	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial inner membrane (GO:0005743)	0.999	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrial inner membrane presequence translocase complex (GO:0005744)	0.999	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.3	Unknown: HDA	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.96	Experimental: experimental	Human Proteinpedia	PubMed
Extracellular	Extracellular region (GO:0005576)	0.96	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.96	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.91	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Organelle inner membrane (GO:0019866)	0.96	Experimental: experimental	Organelle	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q86XD5

Interaction Score

0.96

Q9BSI4

(UniProtKB/Swiss-Prot/P) Details

TERF1-interacting nuclear factor 2

Q86XD5

Interaction Score

0.96

Q9NUX5

(UniProtKB/Swiss-Prot/P) Details

Protection of telomeres protein 1

Q86XD5

Interaction Score

0.959

Q9Y487

(UniProtKB/Swiss-Prot/P) Details

V-type proton ATPase 116 kDa subunit a isoform 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.971	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endosome membrane (GO:0010008)	0.657	Unknown: traceable author statement	GO	PubMed
Cytosol	Vacuolar proton-transporting V-type ATPase complex (GO:0016471)	0.971	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Vacuolar proton-transporting V-type ATPase, V0 domain (GO:0000220)	0.971	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Lysosomal membrane (GO:0005765)	0.971	Unknown: HDA	GO	PubMed
Secretory-pathway	Phagocytic vesicle membrane (GO:0030670)	0.657	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Acrosomal vesicle (GO:0001669)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.996	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.996	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.996	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q86XD5

Interaction Score

0.948

Q5MJ33

(UniProtKB/TrEmbl/P) Details

Protection of telomeres protein 1 variant 4

Q86XD5

Interaction Score

0.899

Q5JTY5

(UniProtKB/Swiss-Prot/P) Details

COBW domain-containing protein 3

Q86XD5

Interaction Score

0.899

Q86TH5

(UniProtKB/TrEmbl/P) Details

ARFGEF2 protein

Q86XD5

Interaction Score

0.899

Q59FR3

(UniProtKB/TrEmbl/P) Details

ADP-ribosylation factor guanine nucleotide-exchange factor 2 variant

Q86XD5

Interaction Score

0.843

A0A0A0MQY7

(UniProtKB/TrEmbl/P) Details

VWFA and cache domain-containing protein 1

Q86XD5

Interaction Score

0.843

Q5VU97

(UniProtKB/Swiss-Prot/P) Details

VWFA and cache domain-containing protein 1

Q86XD5

Interaction Score

0.79

P16260

(UniProtKB/Swiss-Prot/P) Details

Graves disease carrier protein

Q86XD5

Interaction Score

0.79

Q9BRX8

(UniProtKB/Swiss-Prot/P) Details

Redox-regulatory protein FAM213A

Q86XD5

Interaction Score

0.79

Q9Y619

(UniProtKB/Swiss-Prot/P) Details

Mitochondrial ornithine transporter 1

Q86XD5

Interaction Score

0.79

P07919

(UniProtKB/Swiss-Prot/P) Details

Cytochrome b-c1 complex subunit 6, mitochondrial

Q86XD5

Interaction Score

0.768

B4DFJ1

(UniProtKB/TrEmbl/P) Details

cDNA FLJ53728, highly similar to TERF1-interacting nuclear factor 2

Q86XD5

Interaction Score

0.768

Q86TW2

(UniProtKB/Swiss-Prot/P) Details

Uncharacterized aarF domain-containing protein kinase 1

Q86XD5

Interaction Score

0.768

Q9BSF4

(UniProtKB/Swiss-Prot/P) Details

Mitochondrial import inner membrane translocase subunit Tim29

Q86XD5

Interaction Score

0.768

A8MTK3

(UniProtKB/TrEmbl/P) Details

POT1 protection of telomeres 1 homolog (S. pombe), isoform CRA_a

Q86XD5

Interaction Score

0.692

A0A0A0MRU4

(UniProtKB/TrEmbl/P) Details

COBW domain-containing protein 3

Q86XD5

Interaction Score

0.296

Q9BPX6

(UniProtKB/Swiss-Prot/P) Details

Calcium uptake protein 1, mitochondrial

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular (GO:0005622)	0.3	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: SVM decision tree	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial intermembrane space (GO:0005758)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Uniplex complex (GO:1990246)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrial inner membrane (GO:0005743)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Integral to mitochondrial membrane (GO:0032592)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Calcium channel complex (GO:0034704)	0.7	Predicted: inferred from sequence or structural similarity	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q86XD5

Interaction Score

Q53X12

(UniProtKB/TrEmbl/P) Details

V-type proton ATPase subunit a

Q86XD5

Interaction Score

Q53ET5

(UniProtKB/TrEmbl/P) Details

V-type proton ATPase subunit a

Q86XD5

Interaction Score

Q5CZH6

(UniProtKB/TrEmbl/P) Details

V-type proton ATPase subunit a

Q86XD5

Interaction Score

A0A0A6YYH9

(UniProtKB/TrEmbl/P) Details

COBW domain-containing protein 5

Q86XD5

Interaction Score

A0A087WWG3

(UniProtKB/TrEmbl/P) Details

COBW domain-containing protein 3

Q86XD5

Interaction Score

Q6I9V5

(UniProtKB/TrEmbl/P) Details

SLC25A6 protein

Q86XD5

Interaction Score

A0A286YF11

(UniProtKB/TrEmbl/P) Details

Calcium uptake protein 1, mitochondrial

Q86XD5

Interaction Score

Q567R0

(UniProtKB/TrEmbl/P) Details

UQCRH protein

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Q86XD5

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

Q86XD5

P53350

Serine/threonine-protein kinase PLK1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86XD5

O14965

Aurora kinase A

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86XD5

Q99741

Cell division control protein 6 homolog

Localizations:

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Interaction Source Publication:

Q86XD5

Q9UNY4

Transcription termination factor 2

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86XD5

Q93050

V-type proton ATPase 116 kDa subunit a isoform 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86XD5

P11388

DNA topoisomerase 2-alpha

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86XD5

Q15788

Nuclear receptor coactivator 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86XD5

Q13459

Unconventional myosin-IXb

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86XD5

Q9Y6D5

Brefeldin A-inhibited guanine nucleotide-exchange protein 2

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86XD5

Q9UK61

Protein TASOR

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86XD5

Q96EE3

Nucleoporin SEH1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86XD5

Q9BSJ5

Uncharacterized protein C17orf80

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86XD5