Q92545

Transmembrane protein 131 // UniProt Profile

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Species	H. sapiens
Number of Interactions	29 / 40
Average Interaction Score	0.888

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
N/A	Cellular component (GO:0005575)	0.3	Unknown: no biological data available	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.853	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.853	Unknown: unspecified method	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Intermediate filament cytoskeleton (GO:0045111)	0.853	Unknown: unspecified method	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.937	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.937	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.937	Unknown: inferred from electronic annotation	GO	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

Q92545

Interaction Score

0.999

Q93086

(UniProtKB/Swiss-Prot/P) Details

P2X purinoceptor 5

Q92545

Interaction Score

0.998

Q9Y275

(UniProtKB/Swiss-Prot/P) Details

Tumor necrosis factor ligand superfamily member 13B

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.8	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.96	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.96	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.994	Experimental: experimental	eSLDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.994	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.994	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.994	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Membrane (GO:0016020)	0.996	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.996	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.996	Unknown: non-traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.996	Experimental: experimental	Organelle	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q92545

Interaction Score

0.997

P04629

(UniProtKB/Swiss-Prot/P) Details

High affinity nerve growth factor receptor

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Neuronal cell body (GO:0043025)	0.897	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.897	Unknown: unspecified method	The Human Protein Atlas	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.897	Unknown: unspecified method	The Human Protein Atlas	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.7	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.994	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.994	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Early endosome (GO:0005769)	0.994	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Late endosome membrane (GO:0031902)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Early endosome membrane (GO:0031901)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Late endosome (GO:0005770)	0.994	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Lysosome (GO:0005764)	0.897	Predicted: pTarget method	LOCATE	PubMed
Membrane	Dendrite (GO:0030425)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Axon (GO:0030424)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Receptor complex (GO:0043235)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q92545

Interaction Score

0.997

Q13635

(UniProtKB/Swiss-Prot/P) Details

Protein patched homolog 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Midbody (GO:0030496)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.96	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.972	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.972	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endocytic vesicle membrane (GO:0030666)	0.972	Unknown: traceable author statement	GO	PubMed
Membrane	Dendritic growth cone (GO:0044294)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Postsynaptic density (GO:0014069)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Axonal growth cone (GO:0044295)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Cilium membrane (GO:0060170)	1	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Caveola (GO:0005901)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q92545

Interaction Score

0.996

Q8TDD5

(UniProtKB/Swiss-Prot/P) Details

Mucolipin-3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.902	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleolus (GO:0005730)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Late endosome membrane (GO:0031902)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Early endosome membrane (GO:0031901)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Autophagic vacuole membrane (GO:0000421)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Lysosomal membrane (GO:0005765)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.956	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.956	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.956	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.956	Predicted: PAML algorithm	PA-GOSUB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q92545

Interaction Score

0.995

Q16635

(UniProtKB/Swiss-Prot/P) Details

Tafazzin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.86	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.996	Predicted: SVM decision tree	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.996	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.996	Predicted: pTarget method	LOCATE	PubMed
Mitochondrion	Mitochondrial membrane (GO:0031966)	0.996	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Mitochondrion	Mitochondrial inner membrane (GO:0005743)	0.996	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.8	Experimental: experimental	Human Proteinpedia	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Intrinsic to membrane (GO:0031224)	0.992	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.992	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.992	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q92545

Interaction Score

0.993

Q3KR37

(UniProtKB/Swiss-Prot/P) Details

GRAM domain-containing protein 1B

Q92545

Interaction Score

0.988

Q9H6Z9

(UniProtKB/Swiss-Prot/P) Details

Egl nine homolog 3

Q92545

Interaction Score

0.986

Q6UX71

(UniProtKB/Swiss-Prot/P) Details

Plexin domain-containing protein 2

Q92545

Interaction Score

0.984

Q86UE6

(UniProtKB/Swiss-Prot/P) Details

Leucine-rich repeat transmembrane neuronal protein 1

Q92545

Interaction Score

0.982

O14764

(UniProtKB/Swiss-Prot/P) Details

Gamma-aminobutyric acid receptor subunit delta

Q92545

Interaction Score

0.981

P13747

(UniProtKB/Swiss-Prot/P) Details

HLA class I histocompatibility antigen, alpha chain E

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	0.992	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Integral to lumenal side of endoplasmic reticulum membrane (GO:0071556)	0.882	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.882	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Recycling endosome membrane (GO:0055038)	0.882	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Early endosome membrane (GO:0031901)	0.882	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Phagocytic vesicle membrane (GO:0030670)	0.882	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	ER to Golgi transport vesicle membrane (GO:0012507)	0.882	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.992	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.992	Unknown: traceable author statement	GO	PubMed
Membrane	MHC class I protein complex (GO:0042612)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.3	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q92545

Interaction Score

0.977

P34903

(UniProtKB/Swiss-Prot/P) Details

Gamma-aminobutyric acid receptor subunit alpha-3

Q92545

Interaction Score

0.971

Q9HAT2

(UniProtKB/Swiss-Prot/P) Details

Sialate O-acetylesterase

Q92545

Interaction Score

0.962

P59665

(UniProtKB/Swiss-Prot/P) Details

Neutrophil defensin 1

Q92545

Interaction Score

0.945

Q6UWQ5

(UniProtKB/Swiss-Prot/P) Details

Lysozyme-like protein 1

Q92545

Interaction Score

0.942

Q15388

(UniProtKB/Swiss-Prot/P) Details

Mitochondrial import receptor subunit TOM20 homolog

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	Human Proteinpedia	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: pTarget method	LOCATE	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	Organelle	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial outer membrane (GO:0005741)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrial outer membrane translocase complex (GO:0005742)	1	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Integral to mitochondrial outer membrane (GO:0031307)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.96	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.96	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.8	Experimental: experimental	eSLDB	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q92545

Interaction Score

0.906

Q96S52

(UniProtKB/Swiss-Prot/P) Details

GPI transamidase component PIG-S

Q92545

Interaction Score

0.896

A0A024R3M2

(UniProtKB/TrEmbl/P) Details

GRAM domain-containing protein 1B

Q92545

Interaction Score

0.896

A0A2R8Y5X2

(UniProtKB/TrEmbl/P) Details

GRAM domain-containing protein 1B

Q92545

Interaction Score

0.891

Q6DU44

(UniProtKB/TrEmbl/P) Details

HLA class I histocompatibility antigen, alpha chain E

Q92545

Interaction Score

0.851

Q9NRD1

(UniProtKB/Swiss-Prot/P) Details

F-box only protein 6

Q92545

Interaction Score

0.7

Q8NI27

(UniProtKB/Swiss-Prot/P) Details

THO complex subunit 2

Q92545

Interaction Score

0.7

Q6PD62

(UniProtKB/Swiss-Prot/P) Details

RNA polymerase-associated protein CTR9 homolog

Q92545

Interaction Score

0.673

P04179

(UniProtKB/Swiss-Prot/P) Details

Superoxide dismutase [Mn], mitochondrial

Q92545

Interaction Score

0.656

O19682

(UniProtKB/TrEmbl/P) Details

HLA-E

Q92545

Interaction Score

0.656

Q8NBL9

(UniProtKB/TrEmbl/P) Details

cDNA PSEC0119 fis, clone PLACE1002376, highly similar to GPI transamidase component PIG-S

Q92545

Interaction Score

0.64

X5DR71

(UniProtKB/TrEmbl/P) Details

Tyrosine-protein kinase receptor

Q92545

Interaction Score

0.597

Q13438

(UniProtKB/Swiss-Prot/P) Details

Protein OS-9

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Q92545

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

Q92545

Q93086

P2X purinoceptor 5

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q92545

Q9Y275

Tumor necrosis factor ligand superfamily member 13B

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q92545

P04629

High affinity nerve growth factor receptor

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q92545

Q13635

Protein patched homolog 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q92545

Q8TDD5

Mucolipin-3

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q92545

Q16635

Tafazzin

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q92545

Q3KR37

GRAM domain-containing protein 1B

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q92545

Q9H6Z9

Egl nine homolog 3

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q92545

Q6UX71

Plexin domain-containing protein 2

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q92545

Q86UE6

Leucine-rich repeat transmembrane neuronal protein 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q92545

O14764

Gamma-aminobutyric acid receptor subunit delta

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q92545

P13747

HLA class I histocompatibility antigen, alpha chain E

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q92545