Q969R8

KICSTOR complex protein ITFG2    //   UniProt Profile 

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Species

 H. sapiens

Number of Interactions

 18 / 19

Average Interaction Score

 0.957

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.958 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytosol (GO:0005829) 0.958 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.86 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Lysosomal membrane (GO:0005765) 0.958 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.96 Experimental: experimental MatrixDB PubMed 
Extracellular Intercellular bridge (GO:0045171) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.


Interactions

All Details

Q969R8

Interaction Score
1

Q07912

(UniProtKB/Swiss-Prot/P) Details

Activated CDC42 kinase 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Coated pit (GO:0005905) 0.998 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.998 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.998 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.998 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 0.998 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endosome (GO:0005768) 0.958 Predicted: inferred from sequence or structural similarity GO PubMed 
Secretory-pathway Cytoplasmic vesicle membrane (GO:0030659) 0.958 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Clathrin-coated vesicle (GO:0030136) 0.958 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.998 Unknown: HDA GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.998 Predicted: SVM decision tree eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.998 Experimental: inferred from direct assay GO PubMed 
Membrane Extrinsic to internal side of plasma membrane (GO:0031234) 0.998 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Grb2-EGFR complex (GO:0070436) 0.998 Experimental: inferred from direct assay GO PubMed 
Membrane Adherens junction (GO:0005912) 0.998 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

HPRD, IntAct

Interaction Source Publication:

PubMed 

Q969R8

Interaction Score
0.999

Q96DN2

(UniProtKB/Swiss-Prot/P) Details

von Willebrand factor C and EGF domain-containing protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.992 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.992 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.992 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.958 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.958 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular matrix (GO:0031012) 0.958 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q969R8

Interaction Score
0.999

O75140

(UniProtKB/Swiss-Prot/P) Details

GATOR complex protein DEPDC5

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
N/A Iml1 complex (GO:1990130) 0.8 Experimental: inferred from direct assay GO PubMed 
Cytosol Cul3-RING ubiquitin ligase complex (GO:0031463) 0.999 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytosol (GO:0005829) 0.999 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 0.999 Predicted: inferred from sequence or structural similarity GO PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Lysosome (GO:0005764) 0.999 Experimental: inferred from direct assay GO PubMed 
Cytosol Lysosomal membrane (GO:0005765) 0.999 Unknown: HDA GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q969R8

Interaction Score
0.998

Q9Y664

(UniProtKB/Swiss-Prot/P) Details

KICSTOR complex protein kaptin

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.999 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytosol (GO:0005829) 0.999 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.96 Experimental: experimental Organelle PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Lysosomal membrane (GO:0005765) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Stereocilium (GO:0032420) 0.999 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 0.999 Experimental: experimental Organelle PubMed 
Cytosol Filamentous actin (GO:0031941) 0.999 Experimental: inferred from direct assay GO PubMed 
Membrane Lamellipodium (GO:0030027) 0.96 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q969R8

Interaction Score
0.998

Q5T011

(UniProtKB/Swiss-Prot/P) Details

KICSTOR complex protein SZT2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
N/A Iml1 complex (GO:1990130) 0.8 Experimental: inferred from direct assay GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.998 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.94 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Lysosomal membrane (GO:0005765) 0.998 Experimental: inferred from direct assay GO PubMed 
Cytosol Peroxisome (GO:0005777) 0.998 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Actin cytoskeleton (GO:0015629) 0.998 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q969R8

Interaction Score
0.997

Q9Y343

(UniProtKB/Swiss-Prot/P) Details

Sorting nexin-24

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.996 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 0.996 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytoplasm (GO:0005737) 0.996 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.996 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Secretory-pathway Cytoplasmic vesicle membrane (GO:0030659) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q969R8

Interaction Score
0.996

Q9BXJ5

(UniProtKB/Swiss-Prot/P) Details

Complement C1q tumor necrosis factor-related protein 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.96 Experimental: experimental eSLDB PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Centrosome (GO:0005813) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.956 Predicted: pTarget method LOCATE PubMed 
Extracellular Extracellular region (GO:0005576) 0.956 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 0.956 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Collagen (GO:0005581) 0.956 Unknown: inferred from electronic annotation GO PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q969R8

Interaction Score
0.995

Q14145

(UniProtKB/Swiss-Prot/P) Details

Kelch-like ECH-associated protein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cul3-RING ubiquitin ligase complex (GO:0031463) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Midbody (GO:0030496) 0.8 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.988 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.988 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.988 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Microtubule organizing center (GO:0005815) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Microtubule organizing center (GO:0005815) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Actin filament (GO:0005884) 1 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q969R8

Interaction Score
0.995

Q96MD2

(UniProtKB/Swiss-Prot/P) Details

KICSTOR complex protein C12orf66

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Lysosomal membrane (GO:0005765) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Microtubule cytoskeleton (GO:0015630) 0.86 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.96 Experimental: experimental MatrixDB PubMed 
Extracellular Intercellular bridge (GO:0045171) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q969R8

Interaction Score
0.993

Q14258

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin/ISG15 ligase TRIM25

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.988 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.988 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.988 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nuclear body (GO:0016604) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear body (GO:0016604) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q969R8

Interaction Score
0.99

A1X283

(UniProtKB/Swiss-Prot/P) Details

SH3 and PX domain-containing protein 2B

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.973 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.973 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.988 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.988 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Fibrillar center (GO:0001650) 0.988 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Podosome (GO:0002102) 0.973 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Cell projection (GO:0042995) 0.51 Unknown: inferred from electronic annotation GO PubMed 
Membrane Cell junction (GO:0030054) 0.51 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q969R8

Interaction Score
0.981

Q9BQS6

(UniProtKB/Swiss-Prot/P) Details

Heat shock protein beta-9

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.94 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q969R8

Interaction Score
0.96

Q1RMZ1

(UniProtKB/Swiss-Prot/P) Details

S-adenosylmethionine sensor upstream of mTORC1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
N/A Iml1 complex (GO:1990130) 0.8 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.94 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytosol (GO:0005829) 0.94 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleolus (GO:0005730) 0.7 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q969R8

Interaction Score
0.959

Q14642

(UniProtKB/Swiss-Prot/P) Details

Type I inositol 1,4,5-trisphosphate 5-phosphatase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Intracellular (GO:0005622) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytosol (GO:0005829) 0.86 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.902 Experimental: experimental eSLDB PubMed 
Membrane Membrane (GO:0016020) 0.902 Unknown: non-traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.902 Unknown: traceable author statement GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q969R8

Interaction Score
0.957

Q7KYR7

(UniProtKB/Swiss-Prot/P) Details

Butyrophilin subfamily 2 member A1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to membrane (GO:0016021) 0.994 Predicted: SVM decision tree eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.994 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.994 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 0.994 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Integral to plasma membrane (GO:0005887) 0.994 Unknown: traceable author statement GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q969R8

Interaction Score
0.947

Q86WR7

(UniProtKB/Swiss-Prot/P) Details

Proline and serine-rich protein 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.79 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytosol (GO:0005829) 0.79 Unknown: unspecified method The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.91 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 0.91 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Plasma membrane (GO:0005886) 0.3 Unknown: unspecified method The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q969R8

Interaction Score
0.826

G3V144

(UniProtKB/TrEmbl/P) Details

SH3 and PX domain-containing protein 2B

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Fibrillar center (GO:0001650) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q969R8

Interaction Score
0.64

A0A2R8Y6H3

(UniProtKB/TrEmbl/P) Details

GATOR complex protein DEPDC5

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Golgi apparatus (GO:0005794) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

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ComPPI is published in Nucleic Acids Research Database Issue 2015