Q969W9

Protein TMEPAI // UniProt Profile

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Species	H. sapiens
Number of Interactions	12 / 17
Average Interaction Score	0.798

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.96	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.998	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Early endosome membrane (GO:0031901)	0.998	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endosome membrane (GO:0010008)	0.998	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.902	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.902	Unknown: non-traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.902	Unknown: traceable author statement	GO	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

Q969W9

Interaction Score

O14964

(UniProtKB/Swiss-Prot/P) Details

Hepatocyte growth factor-regulated tyrosine kinase substrate

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endosome (GO:0005768)	1	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endosome (GO:0005768)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Early endosome (GO:0005769)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Early endosome membrane (GO:0031901)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Multivesicular body membrane (GO:0032585)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	ESCRT-0 complex (GO:0033565)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Lysosome (GO:0005764)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Lysosome (GO:0005764)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.8	Experimental: experimental	eSLDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q969W9

Interaction Score

Q86VP6

(UniProtKB/Swiss-Prot/P) Details

Cullin-associated NEDD8-dissociated protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Ubiquitin ligase complex (GO:0000151)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cullin-RING ubiquitin ligase complex (GO:0031461)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.972	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.972	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Secretory granule lumen (GO:0034774)	0.972	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.86	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	0.86	Experimental: experimental	MatrixDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q969W9

Interaction Score

0.999

P46934

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase NEDD4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Ubiquitin ligase complex (GO:0000151)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cell cortex (GO:0005938)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.8	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Chromatin (GO:0000785)	0.8	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.86	Experimental: inferred from mutant phenotype	GO	PubMed
Membrane	Apicolateral plasma membrane (GO:0016327)	0.86	Unknown: traceable author statement	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

HPRD, BioGRID

Interaction Source Publication:

PubMed

Q969W9

Interaction Score

0.998

Q9NRR5

(UniProtKB/Swiss-Prot/P) Details

Ubiquilin-4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytosolic proteasome complex (GO:0031597)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear proteasome complex (GO:0031595)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.958	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.958	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Autophagic vacuole (GO:0005776)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.958	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

HPRD, IntAct, BioGRID

Interaction Source Publication:

Androgen receptor

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.86	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.86	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear chromatin (GO:0000790)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.3	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q969W9

Interaction Score

0.826

Q9BTE1

(UniProtKB/Swiss-Prot/P) Details

Dynactin subunit 5

Q969W9

Interaction Score

Q9NUA2

(UniProtKB/TrEmbl/P) Details

Androgen receptor

Q969W9

Interaction Score

A0A087WUX9

(UniProtKB/TrEmbl/P) Details

Androgen receptor

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Q969W9

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

Q969W9

O14964

Hepatocyte growth factor-regulated tyrosine kinase substrate

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q969W9

Q86VP6

Cullin-associated NEDD8-dissociated protein 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q969W9

P46934

E3 ubiquitin-protein ligase NEDD4

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q969W9

Q9NRR5

Ubiquilin-4

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q969W9

O00399

Dynactin subunit 6

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q969W9

Q92783

Signal transducing adapter molecule 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q969W9

Q59F94

Ataxin-1 ubiquitin-like interacting protein variant

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q969W9

Q14258

E3 ubiquitin/ISG15 ligase TRIM25

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q969W9

P10275

Androgen receptor

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q969W9

Q9BTE1

Dynactin subunit 5

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q969W9

Q9NUA2

Androgen receptor

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q969W9

A0A087WUX9

Androgen receptor

Localizations:

Interaction Source Database:

Interaction Source Publication: