Q9BTE1

Dynactin subunit 5    //   UniProt Profile 

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Species

H. sapiens

Number of Interactions

31 / 37

Average Interaction Score

0.813

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.86 Unknown: traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nuclear membrane (GO:0031965) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear membrane (GO:0031965) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Centrosome (GO:0005813) 0.86 Experimental: inferred from direct assay GO PubMed 
Nucleus Condensed chromosome kinetochore (GO:0000777) 1 Unknown: inferred from electronic annotation GO PubMed 

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.


Interactions

All Details

Q9BTE1

Interaction Score
1

P63167

(UniProtKB/Swiss-Prot/P) Details

Dynein light chain 1, cytoplasmic

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Unknown: traceable author statement GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Signalosome (GO:0008180) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nuclear body (GO:0016604) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Tertiary granule membrane (GO:0070821) 0.3 Unknown: traceable author statement GO PubMed 
Cytosol Mitotic spindle (GO:0072686) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasmic dynein complex (GO:0005868) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Centrosome (GO:0005813) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Microtubule (GO:0005874) 1 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Kinetochore (GO:0000776) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Cilium (GO:0005929) 0.657 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.657 Unknown: HDA GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.657 Unknown: traceable author statement GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q9BTE1

Interaction Score
1

Q9NYP9

(UniProtKB/Swiss-Prot/P) Details

Protein Mis18-alpha

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.988 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytosol (GO:0005829) 0.988 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.988 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.997 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.997 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.997 Unknown: traceable author statement GO PubMed 
Nucleus Chromatin (GO:0000785) 0.997 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus Chromosome, centromeric region (GO:0000775) 0.997 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9BTE1

Interaction Score
0.999

Q9UJW0

(UniProtKB/Swiss-Prot/P) Details

Dynactin subunit 4

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Unknown: traceable author statement GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytosol (GO:0005829) 1 Unknown: traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 0.996 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.996 Unknown: traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 0.996 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 0.996 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.8 Experimental: experimental eSLDB PubMed 
Cytosol Cytoskeleton (GO:0005856) 1 Experimental: experimental eSLDB PubMed 
Cytosol Cytoskeleton (GO:0005856) 1 Experimental: experimental Organelle PubMed 
Cytosol Spindle pole (GO:0000922) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasmic dynein complex (GO:0005868) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Dynactin complex (GO:0005869) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Centrosome (GO:0005813) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Centrosome (GO:0005813) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Stress fiber (GO:0001725) 1 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Kinetochore (GO:0000776) 0.996 Unknown: inferred from electronic annotation GO PubMed 
Membrane Focal adhesion (GO:0005925) 0.3 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9BTE1

Interaction Score
0.994

Q14203

(UniProtKB/Swiss-Prot/P) Details

Dynactin subunit 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Cell leading edge (GO:0031252) 0.931 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Retromer complex (GO:0030904) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Neuronal cell body (GO:0043025) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Cell cortex (GO:0005938) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear envelope (GO:0005635) 0.96 Experimental: inferred from direct assay GO PubMed 
Cytosol Intermediate filament cytoskeleton (GO:0045111) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Intermediate filament cytoskeleton (GO:0045111) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Spindle (GO:0005819) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Spindle pole (GO:0000922) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Microtubule associated complex (GO:0005875) 1 Experimental: inferred from mutant phenotype GO PubMed 
Cytosol Dynein complex (GO:0030286) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Dynactin complex (GO:0005869) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Centrosome (GO:0005813) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Centrosome (GO:0005813) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Centriole (GO:0005814) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Microtubule (GO:0005874) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Microtubule plus end (GO:0035371) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Kinetochore (GO:0000776) 0.96 Experimental: inferred from direct assay GO PubMed 
Membrane Neuron projection (GO:0043005) 0.931 Experimental: inferred from direct assay GO PubMed 
Membrane Axon (GO:0030424) 0.931 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.931 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

Q9BTE1

Interaction Score
0.994

Q13561

(UniProtKB/Swiss-Prot/P) Details

Dynactin subunit 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endosome (GO:0005768) 0.8 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Lysosome (GO:0005764) 1 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoskeleton (GO:0005856) 1 Experimental: experimental Organelle PubMed 
Cytosol Dynein complex (GO:0030286) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Dynactin complex (GO:0005869) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Centrosome (GO:0005813) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Centrosome (GO:0005813) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Microtubule (GO:0005874) 1 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Chromosome (GO:0005694) 0.96 Experimental: experimental Organelle PubMed 
Nucleus Kinetochore (GO:0000776) 0.96 Experimental: inferred from direct assay GO PubMed 
Membrane Growth cone (GO:0030426) 0.51 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.51 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Vesicle (GO:0031982) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 1 Unknown: HDA GO PubMed 

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed , PubMed 

Q9BTE1

Interaction Score
0.994

Q93062

(UniProtKB/Swiss-Prot/P) Details

RNA-binding protein with multiple splicing

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.999 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasmic stress granule (GO:0010494) 0.999 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasmic mRNA processing body (GO:0000932) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Cytosol U1 snRNP (GO:0005685) 0.999 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Cytosol (GO:0005829) 0.999 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.999 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.96 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

Q9BTE1

Interaction Score
0.991

Q3KP66

(UniProtKB/Swiss-Prot/P) Details

Innate immunity activator protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.982 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.982 Experimental: inferred from mutant phenotype GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.982 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Experimental: inferred from mutant phenotype GO PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Predicted: pTarget method LOCATE PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9BTE1

Interaction Score
0.987

Q1MSJ5

(UniProtKB/Swiss-Prot/P) Details

Centrosome and spindle pole-associated protein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.91 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.91 Predicted: pTarget method LOCATE PubMed 
Cytosol Spindle (GO:0005819) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Spindle pole (GO:0000922) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Microtubule organizing center (GO:0005815) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Centrosome (GO:0005813) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Microtubule (GO:0005874) 1 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9BTE1

Interaction Score
0.98

O00399

(UniProtKB/Swiss-Prot/P) Details

Dynactin subunit 6

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.998 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.998 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.998 Unknown: traceable author statement GO PubMed 
Cytosol Cytosol (GO:0005829) 0.998 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.8 Experimental: experimental Organelle PubMed 
Nucleus Nucleolus (GO:0005730) 0.86 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Dynactin complex (GO:0005869) 0.998 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Centrosome (GO:0005813) 0.998 Experimental: inferred from direct assay GO PubMed 
Nucleus Condensed chromosome kinetochore (GO:0000777) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9BTE1

Interaction Score
0.972

Q16643

(UniProtKB/Swiss-Prot/P) Details

Drebrin

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Unknown: non-traceable author statement GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.8 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoskeleton (GO:0005856) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 1 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoskeleton (GO:0005856) 1 Experimental: experimental Organelle PubMed 
Cytosol Cortical cytoskeleton (GO:0030863) 1 Unknown: traceable author statement GO PubMed 
Cytosol Actin cytoskeleton (GO:0015629) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Actin cytoskeleton (GO:0015629) 1 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Actin cytoskeleton (GO:0015629) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Actomyosin (GO:0042641) 1 Unknown: non-traceable author statement GO PubMed 
Membrane Growth cone (GO:0030426) 0.997 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Dendrite (GO:0030425) 0.997 Unknown: non-traceable author statement GO PubMed 
Membrane Postsynaptic density (GO:0014069) 0.997 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.997 Experimental: experimental Human Proteinpedia PubMed 
Membrane Plasma membrane (GO:0005886) 0.997 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Gap junction (GO:0005921) 0.997 Unknown: inferred from electronic annotation GO PubMed 
Membrane Postsynaptic membrane (GO:0045211) 0.997 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

Q9BTE1

Interaction Score
0.965

Q9NSJ5

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein DKFZp761J032

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.96 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.8 Experimental: experimental eSLDB PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.8 Experimental: experimental eSLDB PubMed 
Cytosol Cytoskeleton (GO:0005856) 0.96 Experimental: experimental eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9BTE1

Interaction Score
0.938

B4E3T4

(UniProtKB/TrEmbl/P) Details

HCG2043421, isoform CRA_c

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9BTE1

Interaction Score
0.91

Q9H688

(UniProtKB/TrEmbl/P) Details

cDNA: FLJ22490 fis, clone HRC10983

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.91 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.91 Predicted: pTarget method LOCATE PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9BTE1

Interaction Score
0.902

O95198

(UniProtKB/Swiss-Prot/P) Details

Kelch-like protein 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cul3-RING ubiquitin ligase complex (GO:0031463) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Unknown: traceable author statement GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 1 Unknown: unspecified method The Human Protein Atlas PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.3 Unknown: unspecified method The Human Protein Atlas PubMed 
Cytosol Cytoskeleton (GO:0005856) 1 Experimental: experimental Organelle PubMed 
Cytosol Actin cytoskeleton (GO:0015629) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Ruffle (GO:0001726) 0.51 Unknown: inferred from electronic annotation GO PubMed 
Membrane Lamellipodium (GO:0030027) 0.51 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9BTE1

Interaction Score
0.881

Q969F0

(UniProtKB/Swiss-Prot/P) Details

Fetal and adult testis-expressed transcript protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Mitochondrion Mitochondrial outer membrane (GO:0005741) 0.8 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: pTarget method LOCATE PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.972 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.972 Experimental: experimental Human Proteinpedia PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 0.972 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.3 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed 

Q9BTE1

Interaction Score
0.86

Q14204

(UniProtKB/Swiss-Prot/P) Details

Cytoplasmic dynein 1 heavy chain 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Unknown: traceable author statement GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Azurophil granule lumen (GO:0035578) 0.3 Unknown: traceable author statement GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 1 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoskeleton (GO:0005856) 1 Experimental: experimental Organelle PubMed 
Cytosol Cytoplasmic dynein complex (GO:0005868) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Centrosome (GO:0005813) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Centrosome (GO:0005813) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Microtubule (GO:0005874) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Filopodium (GO:0030175) 0.902 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.972 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.972 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular matrix (GO:0031012) 0.972 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.902 Unknown: HDA GO PubMed 
Membrane Membrane (GO:0016020) 0.902 Experimental: experimental MatrixDB PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 1 Unknown: HDA GO PubMed 

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed 

Q9BTE1

Interaction Score
0.86

P61163

(UniProtKB/Swiss-Prot/P) Details

Alpha-centractin

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Myelin sheath (GO:0043209) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Unknown: traceable author statement GO PubMed 
Secretory-pathway COPI-coated vesicle (GO:0030137) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 1 Experimental: experimental Organelle PubMed 
Cytosol Microtubule cytoskeleton (GO:0015630) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Microtubule cytoskeleton (GO:0015630) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Manchette (GO:0002177) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Microtubule associated complex (GO:0005875) 1 Unknown: traceable author statement GO PubMed 
Cytosol Dynactin complex (GO:0005869) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Centrosome (GO:0005813) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Centriole (GO:0005814) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 1 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9BTE1

Interaction Score
0.86

P42025

(UniProtKB/Swiss-Prot/P) Details

Beta-centractin

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Unknown: traceable author statement GO PubMed 
Secretory-pathway Secretory granule lumen (GO:0034774) 0.3 Unknown: traceable author statement GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 1 Experimental: experimental Organelle PubMed 
Cytosol Microtubule cytoskeleton (GO:0015630) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Microtubule cytoskeleton (GO:0015630) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Dynactin complex (GO:0005869) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Centrosome (GO:0005813) 1 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.86 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.86 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.86 Unknown: HDA GO PubMed 
Membrane Membrane (GO:0016020) 0.86 Experimental: experimental MatrixDB PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 1 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9BTE1

Interaction Score
0.859

P47755

(UniProtKB/Swiss-Prot/P) Details

F-actin-capping protein subunit alpha-2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.999 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.999 Unknown: traceable author statement GO PubMed 
Cytosol Cytosol (GO:0005829) 0.999 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Cytoskeleton (GO:0005856) 0.999 Experimental: experimental Organelle PubMed 
Cytosol Cortical cytoskeleton (GO:0030863) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Actin cytoskeleton (GO:0015629) 0.999 Unknown: traceable author statement GO PubMed 
Cytosol F-actin capping protein complex (GO:0008290) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Membrane Brush border (GO:0005903) 0.902 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.86 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.86 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.902 Unknown: inferred from electronic annotation GO PubMed 
Membrane Membrane (GO:0016020) 0.902 Experimental: experimental MatrixDB PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.999 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed , PubMed 

Q9BTE1

Interaction Score
0.858

Q9Y2I6

(UniProtKB/Swiss-Prot/P) Details

Ninein-like protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.998 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.998 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.998 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.998 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Microtubule organizing center (GO:0005815) 0.998 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Microtubule (GO:0005874) 0.998 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Intercellular bridge (GO:0045171) 0.96 Experimental: inferred from direct assay GO PubMed 
Extracellular Intercellular bridge (GO:0045171) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed 

Q9BTE1

Interaction Score
0.857

Q9NPQ8

(UniProtKB/Swiss-Prot/P) Details

Synembryn-A

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.996 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.996 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.996 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytosol (GO:0005829) 0.996 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.7 Predicted: inferred from sequence or structural similarity GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9BTE1

Interaction Score
0.85

A4D0V4

(UniProtKB/TrEmbl/P) Details

Capping protein (Actin filament) muscle Z-line, alpha 2, isoform CRA_b

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.988 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.988 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoskeleton (GO:0005856) 0.988 Experimental: experimental Human Proteinpedia PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9BTE1

Interaction Score
0.845

Q96HB5

(UniProtKB/Swiss-Prot/P) Details

Coiled-coil domain-containing protein 120

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.982 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.982 Predicted: PAML algorithm PA-GOSUB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.3 Unknown: unspecified method The Human Protein Atlas PubMed 
Secretory-pathway Endosome (GO:0005768) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Centriole (GO:0005814) 0.982 Experimental: inferred from direct assay GO PubMed 
Membrane Growth cone (GO:0030426) 0.3 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9BTE1

Interaction Score
0.826

Q969W9

(UniProtKB/Swiss-Prot/P) Details

Protein TMEPAI

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.998 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.96 Experimental: inferred from direct assay GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Golgi membrane (GO:0000139) 0.998 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Early endosome membrane (GO:0031901) 0.998 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endosome membrane (GO:0010008) 0.998 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.902 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.902 Unknown: non-traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.902 Unknown: traceable author statement GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9BTE1

Interaction Score
0.688

Q9GZP0

(UniProtKB/Swiss-Prot/P) Details

Platelet-derived growth factor D

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.971 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Endoplasmic reticulum lumen (GO:0005788) 0.971 Unknown: traceable author statement GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.971 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Golgi membrane (GO:0000139) 0.971 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.981 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.981 Predicted: pTarget method LOCATE PubMed 
Extracellular Extracellular region (GO:0005576) 0.981 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 0.981 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9BTE1

Interaction Score
0.688

Q6MZZ3

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein DKFZp686I0746

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.8 Experimental: experimental eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9BTE1

Interaction Score
0.688

P07919

(UniProtKB/Swiss-Prot/P) Details

Cytochrome b-c1 complex subunit 6, mitochondrial

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Mitochondrion Mitochondrion (GO:0005739) 1 Experimental: experimental eSLDB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 1 Unknown: HDA GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 1 Predicted: pTarget method LOCATE PubMed 
Mitochondrion Mitochondrion (GO:0005739) 1 Experimental: experimental Organelle PubMed 
Mitochondrion Mitochondrion (GO:0005739) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Mitochondrion Mitochondrial inner membrane (GO:0005743) 1 Unknown: traceable author statement GO PubMed 
Mitochondrion Mitochondrial respiratory chain (GO:0005746) 1 Unknown: traceable author statement GO PubMed 
Mitochondrion Mitochondrial respiratory chain complex III (GO:0005750) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental eSLDB PubMed 
Cytosol Organelle inner membrane (GO:0019866) 0.8 Experimental: experimental Organelle PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9BTE1

Interaction Score
0.481

B4DFZ5

(UniProtKB/TrEmbl/P) Details

cDNA FLJ60241, highly similar to Kelch-like protein 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.3 Unknown: unspecified method The Human Protein Atlas PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.3 Unknown: unspecified method The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9BTE1

Interaction Score
0.481

E9PEX9

(UniProtKB/TrEmbl/P) Details

Kelch-like protein 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.3 Unknown: unspecified method The Human Protein Atlas PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.3 Unknown: unspecified method The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9BTE1

Interaction Score
0

Q567R0

(UniProtKB/TrEmbl/P) Details

UQCRH protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9BTE1

Interaction Score
0

Q9H1M4

(UniProtKB/Swiss-Prot/P) Details

Beta-defensin 127

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.8 Experimental: experimental eSLDB PubMed 
N/A Cellular component (GO:0005575) 0.3 Unknown: no biological data available GO PubMed 
Membrane Cell surface (GO:0009986) 0.94 Predicted: inferred from biological aspect of ancestor GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.937 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.937 Predicted: pTarget method LOCATE PubMed 
Extracellular Extracellular region (GO:0005576) 0.937 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Membrane (GO:0016020) 0.94 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

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ComPPI is published in Nucleic Acids Research Database Issue 2015