O43482

Protein Mis18-beta // UniProt Profile

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Species	H. sapiens
Number of Interactions	210 / 260
Average Interaction Score	0.886

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Cajal body (GO:0015030)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Chromatin (GO:0000785)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Chromocenter (GO:0010369)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Chromosome, centromeric region (GO:0000775)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed

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Interactions

All Details

O43482

Interaction Score

P37198

(UniProtKB/Swiss-Prot/P) Details

Nuclear pore glycoprotein p62

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Flemming body (GO:0090543)	0.8	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Endomembrane system (GO:0012505)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Unknown: non-traceable author statement	GO	PubMed
Mitochondrion	Pore complex (GO:0046930)	0.8	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear membrane (GO:0031965)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear membrane (GO:0031965)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear envelope (GO:0005635)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear pore (GO:0005643)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nuclear pore central transport channel (GO:0044613)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.86	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Mitotic spindle (GO:0072686)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Spindle pole (GO:0000922)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Annulate lamellae (GO:0005642)	0.86	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

CCSB, BioGRID, IntAct

Interaction Source Publication:

PubMed

O43482

Interaction Score

P14678

(UniProtKB/Swiss-Prot/P) Details

Small nuclear ribonucleoprotein-associated proteins B and B'

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Ribonucleoprotein complex (GO:0030529)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Small nuclear ribonucleoprotein complex (GO:0030532)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Telomerase holoenzyme complex (GO:0005697)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Histone pre-mRNA 3'end processing complex (GO:0071204)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	U1 snRNP (GO:0005685)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	U2 snRNP (GO:0005686)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	U4 snRNP (GO:0005687)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	U4/U6 x U5 tri-snRNP complex (GO:0046540)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	U5 snRNP (GO:0005682)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	U7 snRNP (GO:0005683)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	SMN-Sm protein complex (GO:0034719)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Methylosome (GO:0034709)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Spliceosomal complex (GO:0005681)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	U2-type catalytic step 2 spliceosome (GO:0071007)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	U2-type prespliceosome (GO:0071004)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	U12-type spliceosomal complex (GO:0005689)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Catalytic step 2 spliceosome (GO:0071013)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

O43482

Interaction Score

Q8NCD3

(UniProtKB/Swiss-Prot/P) Details

Holliday junction recognition protein

O43482

Interaction Score

O75934

(UniProtKB/Swiss-Prot/P) Details

Pre-mRNA-splicing factor SPF27

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Prp19 complex (GO:0000974)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Ribonucleoprotein complex (GO:0030529)	0.992	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Spliceosomal complex (GO:0005681)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Precatalytic spliceosome (GO:0071011)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	U2-type catalytic step 2 spliceosome (GO:0071007)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Catalytic step 2 spliceosome (GO:0071013)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Centrosome (GO:0005813)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	DNA replication factor A complex (GO:0005662)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

O43482

Interaction Score

Q9UBB9

(UniProtKB/Swiss-Prot/P) Details

Tuftelin-interacting protein 11

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.972	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.972	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Spliceosomal complex (GO:0005681)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	U2-type post-mRNA release spliceosomal complex (GO:0071008)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Catalytic step 2 spliceosome (GO:0071013)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear chromosome, telomeric region (GO:0000784)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.86	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

O43482

Interaction Score

P29084

(UniProtKB/Swiss-Prot/P) Details

Transcription initiation factor IIE subunit beta

O43482

Interaction Score

P61244

(UniProtKB/Swiss-Prot/P) Details

Protein max

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.86	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	PML body (GO:0016605)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	MLL1 complex (GO:0071339)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	RNA polymerase II transcription factor complex (GO:0090575)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Protein-DNA complex (GO:0032993)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear chromatin (GO:0000790)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Dendrite (GO:0030425)	0.3	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

O43482

Interaction Score

O60341

(UniProtKB/Swiss-Prot/P) Details

Lysine-specific histone demethylase 1A

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Transcription factor complex (GO:0005667)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear chromosome, telomeric region (GO:0000784)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear chromatin (GO:0000790)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

O43482

Interaction Score

P49450

(UniProtKB/Swiss-Prot/P) Details

Histone H3-like centromeric protein A

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.3	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Unknown: HDA	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Chromosome (GO:0005694)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Condensed nuclear chromosome, centromeric region (GO:0000780)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Condensed nuclear chromosome kinetochore (GO:0000778)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear centromeric heterochromatin (GO:0031618)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Chromosome, centromeric region (GO:0000775)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Condensed chromosome inner kinetochore (GO:0000939)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nuclear nucleosome (GO:0000788)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O43482

Interaction Score

O15516

(UniProtKB/Swiss-Prot/P) Details

Circadian locomoter output cycles protein kaput

O43482

Interaction Score

P05412

(UniProtKB/Swiss-Prot/P) Details

Transcription factor AP-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Transcriptional repressor complex (GO:0017053)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	AP1 complex (GO:0035976)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Chromosome (GO:0005694)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nuclear chromosome (GO:0000228)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nuclear euchromatin (GO:0005719)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

O43482

Interaction Score

P0C1Z6

(UniProtKB/Swiss-Prot/P) Details

TCF3 fusion partner

O43482

Interaction Score

O00327

(UniProtKB/Swiss-Prot/P) Details

Aryl hydrocarbon receptor nuclear translocator-like protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Chromatoid body (GO:0033391)	0.988	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.988	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	PML body (GO:0016605)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Transcription factor complex (GO:0005667)	1	Predicted: inferred from physical interaction	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

O43482

Interaction Score

Q969G3

(UniProtKB/Swiss-Prot/P) Details

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Transcriptional repressor complex (GO:0017053)	1	Predicted: inferred from physical interaction	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Unknown: HDA	GO	PubMed
Nucleus	SWI/SNF complex (GO:0016514)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	NBAF complex (GO:0071565)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	NpBAF complex (GO:0071564)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Chromosome (GO:0005694)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nuclear chromosome (GO:0000228)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nuclear chromatin (GO:0000790)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

O43482

Interaction Score

O95619

(UniProtKB/Swiss-Prot/P) Details

YEATS domain-containing protein 4

O43482

Interaction Score

Q14676

(UniProtKB/Swiss-Prot/P) Details

Mediator of DNA damage checkpoint protein 1

O43482

Interaction Score

P42166

(UniProtKB/Swiss-Prot/P) Details

Lamina-associated polypeptide 2, isoform alpha

O43482

Interaction Score

Q9NPJ6

(UniProtKB/Swiss-Prot/P) Details

Mediator of RNA polymerase II transcription subunit 4

O43482

Interaction Score

Q86UW9

(UniProtKB/Swiss-Prot/P) Details

Probable E3 ubiquitin-protein ligase DTX2

O43482

Interaction Score

Q15910

(UniProtKB/Swiss-Prot/P) Details

Histone-lysine N-methyltransferase EZH2

O43482

Interaction Score

Q9NQ94

(UniProtKB/Swiss-Prot/P) Details

APOBEC1 complementation factor

O43482

Interaction Score

Q6NZI2

(UniProtKB/Swiss-Prot/P) Details

Caveolae-associated protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.96	Experimental: experimental	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.999	Unknown: traceable author statement	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.999	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.86	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Membrane raft (GO:0045121)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Caveola (GO:0005901)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

O43482

Interaction Score

Q9UKL0

(UniProtKB/Swiss-Prot/P) Details

REST corepressor 1

O43482

Interaction Score

Q96DF8

(UniProtKB/Swiss-Prot/P) Details

Splicing factor ESS-2 homolog

O43482

Interaction Score

P09067

(UniProtKB/Swiss-Prot/P) Details

Homeobox protein Hox-B5

O43482

Interaction Score

P52435

(UniProtKB/Swiss-Prot/P) Details

DNA-directed RNA polymerase II subunit RPB11-a

O43482

Interaction Score

Q13227

(UniProtKB/Swiss-Prot/P) Details

G protein pathway suppressor 2

O43482

Interaction Score

Q9BZD4

(UniProtKB/Swiss-Prot/P) Details

Kinetochore protein Nuf2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.3	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Chromosome (GO:0005694)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Chromosome, centromeric region (GO:0000775)	1	Unknown: non-traceable author statement	GO	PubMed
Nucleus	Condensed chromosome kinetochore (GO:0000777)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Ndc80 complex (GO:0031262)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

O43482

Interaction Score

O75150

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase BRE1B

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Ubiquitin ligase complex (GO:0000151)	0.997	Experimental: inferred from direct assay	GO	PubMed
Cytosol	HULC complex (GO:0033503)	0.997	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.997	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.997	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Neuron projection (GO:0043005)	0.897	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Nerve terminal (GO:0043679)	0.897	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.897	Unknown: HDA	GO	PubMed
Membrane	Extrinsic to membrane (GO:0019898)	0.897	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O43482

Interaction Score

P31273

(UniProtKB/Swiss-Prot/P) Details

Homeobox protein Hox-C8

O43482

Interaction Score

P17482

(UniProtKB/Swiss-Prot/P) Details

Homeobox protein Hox-B9

O43482

Interaction Score

Q96RU7

(UniProtKB/Swiss-Prot/P) Details

Tribbles homolog 3

O43482

Interaction Score

P12757

(UniProtKB/Swiss-Prot/P) Details

Ski-like protein

O43482

Interaction Score

Q9UPQ7

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase PDZRN3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.999	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.79	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Neuromuscular junction (GO:0031594)	0.79	Predicted: inferred from biological aspect of ancestor	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O43482

Interaction Score

Q14161

(UniProtKB/Swiss-Prot/P) Details

ARF GTPase-activating protein GIT2

O43482

Interaction Score

P13631

(UniProtKB/Swiss-Prot/P) Details

Retinoic acid receptor gamma

O43482

Interaction Score

Q8N720

(UniProtKB/Swiss-Prot/P) Details

Zinc finger protein 655

O43482

Interaction Score

Q9BV90

(UniProtKB/Swiss-Prot/P) Details

U11/U12 small nuclear ribonucleoprotein 25 kDa protein

O43482

Interaction Score

Q9NP66

(UniProtKB/Swiss-Prot/P) Details

High mobility group protein 20A

O43482

Interaction Score

Q5R372

(UniProtKB/Swiss-Prot/P) Details

Rab GTPase-activating protein 1-like

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.988	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.982	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.982	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytosol (GO:0005829)	0.982	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleolus (GO:0005730)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.988	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Early endosome (GO:0005769)	0.988	Experimental: inferred from direct assay	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.7	Predicted: SVM decision tree	eSLDB	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

O43482

Interaction Score

Q9NPD8

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin-conjugating enzyme E2 T

O43482

Interaction Score

Q9NRA8

(UniProtKB/Swiss-Prot/P) Details

Eukaryotic translation initiation factor 4E transporter

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.997	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.997	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoplasmic mRNA processing body (GO:0000932)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.997	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.997	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nuclear speck (GO:0016607)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	PML body (GO:0016605)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

O43482

Interaction Score

Q96PN8

(UniProtKB/Swiss-Prot/P) Details

Testis-specific serine/threonine-protein kinase 3

O43482

Interaction Score

0.999

Q9BZE0

(UniProtKB/Swiss-Prot/P) Details

Zinc finger protein GLIS2

O43482

Interaction Score

0.999

Q9NYP9

(UniProtKB/Swiss-Prot/P) Details

Protein Mis18-alpha

O43482

Interaction Score

0.999

Q9UID3

(UniProtKB/Swiss-Prot/P) Details

Vacuolar protein sorting-associated protein 51 homolog

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.972	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.972	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleolus (GO:0005730)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	GARP complex (GO:0000938)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Trans-Golgi network membrane (GO:0032588)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Recycling endosome (GO:0055037)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.86	Experimental: inferred from direct assay	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.86	Unknown: traceable author statement	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

O43482

Interaction Score

0.999

Q15915

(UniProtKB/Swiss-Prot/P) Details

Zinc finger protein ZIC 1

O43482

Interaction Score

0.999

Q6P0N0

(UniProtKB/Swiss-Prot/P) Details

Mis18-binding protein 1

O43482

Interaction Score

0.999

Q7Z4H7

(UniProtKB/Swiss-Prot/P) Details

HAUS augmin-like complex subunit 6

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nuclear speck (GO:0016607)	0.996	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Spindle (GO:0005819)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	HAUS complex (GO:0070652)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule (GO:0005874)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

O43482

Interaction Score

0.999

Q92949

(UniProtKB/Swiss-Prot/P) Details

Forkhead box protein J1

O43482

Interaction Score

0.999

Q13620

(UniProtKB/Swiss-Prot/P) Details

Cullin-4B

O43482

Interaction Score

0.999

Q6IBW4

(UniProtKB/Swiss-Prot/P) Details

Condensin-2 complex subunit H2

O43482

Interaction Score

0.999

Q96EK4

(UniProtKB/Swiss-Prot/P) Details

THAP domain-containing protein 11

O43482

Interaction Score

0.999

P04049

(UniProtKB/Swiss-Prot/P) Details

RAF proto-oncogene serine/threonine-protein kinase

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.982	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.982	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.982	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.86	Experimental: experimental	Organelle	PubMed
Mitochondrion	Mitochondrial outer membrane (GO:0005741)	0.86	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nuclear speck (GO:0016607)	0.988	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.7	Predicted: inferred from physical interaction	GO	PubMed
Membrane	Pseudopodium (GO:0031143)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.86	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

O43482

Interaction Score

0.999

O43711

(UniProtKB/Swiss-Prot/P) Details

T-cell leukemia homeobox protein 3

O43482

Interaction Score

0.999

P20618

(UniProtKB/Swiss-Prot/P) Details

Proteasome subunit beta type-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Proteasome complex (GO:0000502)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Proteasome core complex (GO:0005839)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Proteasome core complex, beta-subunit complex (GO:0019774)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.994	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.994	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.994	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.994	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Secretory granule lumen (GO:0034774)	0.3	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.3	Unknown: traceable author statement	GO	PubMed
Membrane	Membrane (GO:0016020)	0.8	Experimental: experimental	MatrixDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

O43482

Interaction Score

0.999

Q96PU8

(UniProtKB/Swiss-Prot/P) Details

Protein quaking

O43482

Interaction Score

0.998

O75052

(UniProtKB/Swiss-Prot/P) Details

Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Sarcoplasmic reticulum membrane (GO:0033017)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.982	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.982	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear membrane (GO:0031965)	0.982	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Z disc (GO:0030018)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Sarcolemma (GO:0042383)	0.973	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	T-tubule (GO:0030315)	0.973	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Caveola (GO:0005901)	0.973	Predicted: inferred from sequence or structural similarity	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O43482

Interaction Score

0.998

Q9H596

(UniProtKB/Swiss-Prot/P) Details

Dual specificity protein phosphatase 21

O43482

Interaction Score

0.998

Q7Z3B4

(UniProtKB/Swiss-Prot/P) Details

Nucleoporin p54

O43482

Interaction Score

0.998

Q9HAQ2

(UniProtKB/Swiss-Prot/P) Details

Kinesin-like protein KIF9

O43482

Interaction Score

0.998

Q9NX70

(UniProtKB/Swiss-Prot/P) Details

Mediator of RNA polymerase II transcription subunit 29

O43482

Interaction Score

0.998

Q9UJ41

(UniProtKB/Swiss-Prot/P) Details

Rab5 GDP/GTP exchange factor

O43482

Interaction Score

0.997

Q96P16

(UniProtKB/Swiss-Prot/P) Details

Regulation of nuclear pre-mRNA domain-containing protein 1A

O43482

Interaction Score

0.997

Q53HC9

(UniProtKB/Swiss-Prot/P) Details

EARP-interacting protein

O43482

Interaction Score

0.996

Q8WU58

(UniProtKB/Swiss-Prot/P) Details

Protein FAM222B

O43482

Interaction Score

0.996

P42684

(UniProtKB/Swiss-Prot/P) Details

Tyrosine-protein kinase ABL2

O43482

Interaction Score

0.996

P78424

(UniProtKB/Swiss-Prot/P) Details

POU domain, class 6, transcription factor 2

O43482

Interaction Score

0.996

O14770

(UniProtKB/Swiss-Prot/P) Details

Homeobox protein Meis2

O43482

Interaction Score

0.996

P42167

(UniProtKB/Swiss-Prot/P) Details

Lamina-associated polypeptide 2, isoforms beta/gamma

O43482

Interaction Score

0.995

Q8TAE8

(UniProtKB/Swiss-Prot/P) Details

Growth arrest and DNA damage-inducible proteins-interacting protein 1

O43482

Interaction Score

0.995

O14561

(UniProtKB/Swiss-Prot/P) Details

Acyl carrier protein, mitochondrial

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.7	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial matrix (GO:0005759)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Mitochondrion	Mitochondrial large ribosomal subunit (GO:0005762)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrial membrane (GO:0031966)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Mitochondrion	Mitochondrial inner membrane (GO:0005743)	1	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrial respiratory chain complex I (GO:0005747)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

O43482

Interaction Score

0.994

Q13616

(UniProtKB/Swiss-Prot/P) Details

Cullin-1

O43482

Interaction Score

0.994

Q6P5Z2

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein kinase N3

O43482

Interaction Score

0.993

Q6NSJ2

(UniProtKB/Swiss-Prot/P) Details

Pleckstrin homology-like domain family B member 3

O43482

Interaction Score

0.992

P02533

(UniProtKB/Swiss-Prot/P) Details

Keratin, type I cytoskeletal 14

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Basal part of cell (GO:0045178)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Intermediate filament cytoskeleton (GO:0045111)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Intermediate filament (GO:0005882)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Keratin filament (GO:0045095)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell periphery (GO:0071944)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

O43482

Interaction Score

0.992

P40855

(UniProtKB/Swiss-Prot/P) Details

Peroxisomal biogenesis factor 19

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.96	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Peroxisome (GO:0005777)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Peroxisome (GO:0005777)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Peroxisome (GO:0005777)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Peroxisome (GO:0005777)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Peroxisomal membrane (GO:0005778)	1	Unknown: HDA	GO	PubMed
Membrane	Brush border membrane (GO:0031526)	0.94	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.94	Experimental: experimental	eSLDB	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

O43482

Interaction Score

0.992

O43739

(UniProtKB/Swiss-Prot/P) Details

Cytohesin-3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.3	Unknown: traceable author statement	GO	PubMed
Membrane	Ruffle (GO:0001726)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Experimental: experimental	Organelle	PubMed
Membrane	Extrinsic to internal side of plasma membrane (GO:0031234)	0.999	Experimental: inferred from direct assay	GO	PubMed
Membrane	Adherens junction (GO:0005912)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Tight junction (GO:0005923)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O43482

Interaction Score

0.992

Q8NFW9

(UniProtKB/Swiss-Prot/P) Details

Rab effector MyRIP

O43482

Interaction Score

0.992

Q7Z6R9

(UniProtKB/Swiss-Prot/P) Details

Transcription factor AP-2-delta

O43482

Interaction Score

0.99

O60826

(UniProtKB/Swiss-Prot/P) Details

Coiled-coil domain-containing protein 22

O43482

Interaction Score

0.989

Q6PF18

(UniProtKB/Swiss-Prot/P) Details

MORN repeat-containing protein 3

O43482

Interaction Score

0.988

Q4V328

(UniProtKB/Swiss-Prot/P) Details

GRIP1-associated protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.94	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.79	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Recycling endosome membrane (GO:0055038)	0.79	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendrite (GO:0030425)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Axon (GO:0030424)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Experimental: experimental	MatrixDB	PubMed
Extracellular	Blood microparticle (GO:0072562)	0.86	Unknown: HDA	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.657	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

O43482

Interaction Score

0.988

Q92851

(UniProtKB/Swiss-Prot/P) Details

Caspase-10

O43482

Interaction Score

0.987

Q96BD5

(UniProtKB/Swiss-Prot/P) Details

PHD finger protein 21A

O43482

Interaction Score

0.987

Q13618

(UniProtKB/Swiss-Prot/P) Details

Cullin-3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cul3-RING ubiquitin ligase complex (GO:0031463)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.937	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.937	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.937	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.86	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Polar microtubule (GO:0005827)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Sperm flagellum (GO:0036126)	0.86	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.86	Unknown: HDA	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O43482

Interaction Score

0.987

Q8TD31

(UniProtKB/Swiss-Prot/P) Details

Coiled-coil alpha-helical rod protein 1

O43482

Interaction Score

0.987

O60504

(UniProtKB/Swiss-Prot/P) Details

Vinexin

O43482

Interaction Score

0.986

A8MUM1

(UniProtKB/TrEmbl/P) Details

EARP-interacting protein

O43482

Interaction Score

0.984

O75604

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin carboxyl-terminal hydrolase 2

O43482

Interaction Score

0.982

Q9NQL9

(UniProtKB/Swiss-Prot/P) Details

Doublesex- and mab-3-related transcription factor 3

O43482

Interaction Score

0.981

Q96MY7

(UniProtKB/Swiss-Prot/P) Details

Protein FAM161B

O43482

Interaction Score

0.981

Q86X02

(UniProtKB/Swiss-Prot/P) Details

Cerebellar degeneration-related protein 2-like

O43482

Interaction Score

0.98

Q9Y448

(UniProtKB/Swiss-Prot/P) Details

Small kinetochore-associated protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Mitotic spindle (GO:0072686)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Spindle pole (GO:0000922)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Microtubule plus end (GO:0035371)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Condensed chromosome kinetochore (GO:0000777)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Kinetochore (GO:0000776)	0.902	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

O43482

Interaction Score

0.979

Q8N865

(UniProtKB/Swiss-Prot/P) Details

Uncharacterized protein C7orf31

O43482

Interaction Score

0.978

B7ZAP0

(UniProtKB/Swiss-Prot/P) Details

Rab GTPase-activating protein 1-like, isoform 10

O43482

Interaction Score

0.978

Q5JUK2

(UniProtKB/Swiss-Prot/P) Details

Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1

O43482

Interaction Score

0.978

Q8TDH9

(UniProtKB/Swiss-Prot/P) Details

Biogenesis of lysosome-related organelles complex 1 subunit 5

O43482

Interaction Score

0.976

P0CG20

(UniProtKB/Swiss-Prot/P) Details

Proline-rich protein 35

O43482

Interaction Score

0.974

Q8N443

(UniProtKB/Swiss-Prot/P) Details

RIB43A-like with coiled-coils protein 1

O43482

Interaction Score

0.974

Q96BZ8

(UniProtKB/Swiss-Prot/P) Details

Leukocyte receptor cluster member 1

O43482

Interaction Score

0.973

Q8TAX8

(UniProtKB/TrEmbl/P) Details

MYC associated factor X

O43482

Interaction Score

0.973

Q9H4R4

(UniProtKB/Swiss-Prot/P) Details

Putative nuclear receptor corepressor 1-like protein NCOR1P1

O43482

Interaction Score

0.972

P19012

(UniProtKB/Swiss-Prot/P) Details

Keratin, type I cytoskeletal 15

O43482

Interaction Score

0.972

Q9Y297

(UniProtKB/Swiss-Prot/P) Details

F-box/WD repeat-containing protein 1A

O43482

Interaction Score

0.968

Q9BUW7

(UniProtKB/Swiss-Prot/P) Details

UPF0184 protein C9orf16

O43482

Interaction Score

0.96

Q68DM7

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein DKFZp686G01261

O43482

Interaction Score

0.96

O95872

(UniProtKB/Swiss-Prot/P) Details

G patch domain and ankyrin repeat-containing protein 1

O43482

Interaction Score

0.96

Q8N6Y0

(UniProtKB/Swiss-Prot/P) Details

Usher syndrome type-1C protein-binding protein 1

O43482

Interaction Score

0.96

P06753

(UniProtKB/Swiss-Prot/P) Details

Tropomyosin alpha-3 chain

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.8	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Muscle thin filament tropomyosin (GO:0005862)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Actin filament (GO:0005884)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Stress fiber (GO:0001725)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

O43482

Interaction Score

0.96

F8W0J4

(UniProtKB/TrEmbl/P) Details

YEATS domain-containing protein 4

O43482

Interaction Score

0.959

P04259

(UniProtKB/Swiss-Prot/P) Details

Keratin, type II cytoskeletal 6B

O43482

Interaction Score

0.958

P15056

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein kinase B-raf

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular (GO:0005622)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.79	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.79	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.7	Predicted: inferred from biological aspect of ancestor	GO	PubMed

Interaction Source Database:

HPRD, IntAct

Interaction Source Publication:

PubMed

O43482

Interaction Score

0.958

Q9BVN2

(UniProtKB/Swiss-Prot/P) Details

RUN and SH3 domain-containing protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.79	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.79	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.973	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Early endosome (GO:0005769)	0.973	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.973	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Microtubule (GO:0005874)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Postsynaptic density (GO:0014069)	0.897	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.897	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Cell junction (GO:0030054)	0.897	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Postsynaptic membrane (GO:0045211)	0.897	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

O43482

Interaction Score

0.958

O00233

(UniProtKB/Swiss-Prot/P) Details

26S proteasome non-ATPase regulatory subunit 9

O43482

Interaction Score

0.956

Q9BXY8

(UniProtKB/Swiss-Prot/P) Details

Protein BEX2

O43482

Interaction Score

0.952

Q7Z3H4

(UniProtKB/Swiss-Prot/P) Details

Sterile alpha motif domain-containing protein 7

O43482

Interaction Score

0.95

Q6P1W5

(UniProtKB/Swiss-Prot/P) Details

Uncharacterized protein C1orf94

O43482

Interaction Score

0.948

Q6ZMS7

(UniProtKB/Swiss-Prot/P) Details

Protein ZNF783

O43482

Interaction Score

0.94

Q5SW79

(UniProtKB/Swiss-Prot/P) Details

Centrosomal protein of 170 kDa

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Spindle (GO:0005819)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Centriole (GO:0005814)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule (GO:0005874)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O43482

Interaction Score

0.94

Q96EV8

(UniProtKB/Swiss-Prot/P) Details

Dysbindin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Midbody (GO:0030496)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Midbody (GO:0030496)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Sarcoplasm (GO:0016528)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	BLOC-1 complex (GO:0031083)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.956	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Endosome membrane (GO:0010008)	0.956	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Melanosome membrane (GO:0033162)	0.956	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Synaptic vesicle membrane (GO:0030672)	0.956	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Growth cone (GO:0030426)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Neuron projection (GO:0043005)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Dendritic spine (GO:0043197)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Postsynaptic density (GO:0014069)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Axon (GO:0030424)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Sarcolemma (GO:0042383)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Postsynaptic membrane (GO:0045211)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

O43482

Interaction Score

0.94

K4DI93

(UniProtKB/TrEmbl/P) Details

Cullin 4B, isoform CRA_e

O43482

Interaction Score

0.94

B4DUA7

(UniProtKB/TrEmbl/P) Details

Intersex-like

O43482

Interaction Score

0.94

Q6Q0C0

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase TRAF7

O43482

Interaction Score

0.94

Q9P2A4

(UniProtKB/Swiss-Prot/P) Details

ABI gene family member 3

O43482

Interaction Score

0.94

Q9Y6H1

(UniProtKB/Swiss-Prot/P) Details

Coiled-coil-helix-coiled-coil-helix domain-containing protein 2

O43482

Interaction Score

0.939

Q567U6

(UniProtKB/Swiss-Prot/P) Details

Coiled-coil domain-containing protein 93

O43482

Interaction Score

0.939

Q5SQN1

(UniProtKB/Swiss-Prot/P) Details

Synaptosomal-associated protein 47

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Neuronal cell body (GO:0043025)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.994	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	0.994	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	BLOC-1 complex (GO:0031083)	0.994	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Secretory-pathway	Synaptic vesicle membrane (GO:0030672)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendrite (GO:0030425)	0.937	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	SNARE complex (GO:0031201)	0.937	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.937	Predicted: inferred from biological aspect of ancestor	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O43482

Interaction Score

0.938

Q5VIR6

(UniProtKB/Swiss-Prot/P) Details

Vacuolar protein sorting-associated protein 53 homolog

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.992	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.999	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	GARP complex (GO:0000938)	0.999	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Trans-Golgi network membrane (GO:0032588)	0.999	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Recycling endosome (GO:0055037)	0.999	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endosome membrane (GO:0010008)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.8	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

O43482

Interaction Score

0.936

A1L4K1

(UniProtKB/Swiss-Prot/P) Details

Fibronectin type III and SPRY domain-containing protein 2

O43482

Interaction Score

0.935

Q8TAU3

(UniProtKB/Swiss-Prot/P) Details

Zinc finger protein 417

O43482

Interaction Score

0.934

P21549

(UniProtKB/Swiss-Prot/P) Details

Serine--pyruvate aminotransferase

O43482

Interaction Score

0.933

Q96HZ0

(UniProtKB/TrEmbl/P) Details

PHLDB3 protein

O43482

Interaction Score

0.93

Q96MP8

(UniProtKB/Swiss-Prot/P) Details

BTB/POZ domain-containing protein KCTD7

O43482

Interaction Score

0.928

R4GMQ1

(UniProtKB/TrEmbl/P) Details

Lysine-specific histone demethylase 1A

O43482

Interaction Score

0.928

B7Z3H4

(UniProtKB/TrEmbl/P) Details

Beta-transducin repeat containing isoform 4

O43482

Interaction Score

0.928

B7ZAG0

(UniProtKB/TrEmbl/P) Details

E3 ubiquitin-protein ligase PDZRN3

O43482

Interaction Score

0.928

E7ENB6

(UniProtKB/TrEmbl/P) Details

E3 ubiquitin-protein ligase PDZRN3

O43482

Interaction Score

0.928

Q769H0

(UniProtKB/TrEmbl/P) Details

StAR protein binding protein 1b

O43482

Interaction Score

0.928

F5H8L0

(UniProtKB/TrEmbl/P) Details

Rab GTPase-activating protein 1-like

O43482

Interaction Score

0.928

G3V302

(UniProtKB/TrEmbl/P) Details

Protein max

O43482

Interaction Score

0.928

Q5JXC2

(UniProtKB/Swiss-Prot/P) Details

Migration and invasion-inhibitory protein

O43482

Interaction Score

0.923

Q96D03

(UniProtKB/Swiss-Prot/P) Details

DNA damage-inducible transcript 4-like protein

O43482

Interaction Score

0.91

Q2TB68

(UniProtKB/TrEmbl/P) Details

CCHCR1 protein

O43482

Interaction Score

0.91

Q96L14

(UniProtKB/Swiss-Prot/P) Details

Cep170-like protein

O43482

Interaction Score

0.91

Q9BXU0

(UniProtKB/Swiss-Prot/P) Details

Testis-expressed protein 12

O43482

Interaction Score

0.905

Q9ULW5

(UniProtKB/Swiss-Prot/P) Details

Ras-related protein Rab-26

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.853	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.853	Unknown: unspecified method	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.998	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.998	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Secretory-pathway	Secretory granule membrane (GO:0030667)	0.998	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Synaptic vesicle (GO:0008021)	0.998	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Centrosome (GO:0005813)	0.853	Unknown: unspecified method	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.981	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.981	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.981	Unknown: unspecified method	The Human Protein Atlas	PubMed
Membrane	Intrinsic to plasma membrane (GO:0031226)	0.981	Predicted: inferred from sequence or structural similarity	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

O43482

Interaction Score

0.892

Q8N4L8

(UniProtKB/Swiss-Prot/P) Details

Coiled-coil domain-containing protein 24

O43482

Interaction Score

0.89

Q9BYJ9

(UniProtKB/Swiss-Prot/P) Details

YTH domain-containing family protein 1

O43482

Interaction Score

0.868

Q8N6U2

(UniProtKB/Swiss-Prot/P) Details

Putative uncharacterized protein encoded by LINC00612

O43482

Interaction Score

0.86

Q9NWM3

(UniProtKB/Swiss-Prot/P) Details

CUE domain-containing protein 1

O43482

Interaction Score

0.859

Q15654

(UniProtKB/Swiss-Prot/P) Details

Thyroid receptor-interacting protein 6

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.997	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.997	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.997	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.997	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Interleukin-1 receptor complex (GO:0045323)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

O43482

Interaction Score

0.856

P55040

(UniProtKB/Swiss-Prot/P) Details

GTP-binding protein GEM

O43482

Interaction Score

0.835

Q9BXF9

(UniProtKB/Swiss-Prot/P) Details

Tektin-3

O43482

Interaction Score

0.825

Q2WGJ6

(UniProtKB/Swiss-Prot/P) Details

Kelch-like protein 38

O43482

Interaction Score

0.8

Q9Y6A5

(UniProtKB/Swiss-Prot/P) Details

Transforming acidic coiled-coil-containing protein 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Mitotic spindle (GO:0072686)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Spindle pole (GO:0000922)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O43482

Interaction Score

0.8

G5E972

(UniProtKB/TrEmbl/P) Details

Lamina-associated polypeptide 2, isoforms beta/gamma

O43482

Interaction Score

0.8

Q3ZCT4

(UniProtKB/TrEmbl/P) Details

CLOCK protein

O43482

Interaction Score

0.8

Q53EU0

(UniProtKB/TrEmbl/P) Details

Clock variant

O43482

Interaction Score

0.8

A0A0C4DGQ6

(UniProtKB/TrEmbl/P) Details

Regulation of nuclear pre-mRNA domain-containing protein 1A

O43482

Interaction Score

0.8

O14964

(UniProtKB/Swiss-Prot/P) Details

Hepatocyte growth factor-regulated tyrosine kinase substrate

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endosome (GO:0005768)	1	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endosome (GO:0005768)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Early endosome (GO:0005769)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Early endosome membrane (GO:0031901)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Multivesicular body membrane (GO:0032585)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	ESCRT-0 complex (GO:0033565)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Lysosome (GO:0005764)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Lysosome (GO:0005764)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.8	Experimental: experimental	eSLDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

O43482

Interaction Score

0.8

Q5JVL4

(UniProtKB/Swiss-Prot/P) Details

EF-hand domain-containing protein 1

O43482

Interaction Score

0.8

O43790

(UniProtKB/Swiss-Prot/P) Details

Keratin, type II cuticular Hb6

O43482

Interaction Score

0.8

Q9NNX1

(UniProtKB/Swiss-Prot/P) Details

Tuftelin

O43482

Interaction Score

0.799

O95678

(UniProtKB/Swiss-Prot/P) Details

Keratin, type II cytoskeletal 75

O43482

Interaction Score

0.799

P56539

(UniProtKB/Swiss-Prot/P) Details

Caveolin-3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: experimental	eSLDB	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.972	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.972	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Z disc (GO:0030018)	0.998	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Membrane raft (GO:0045121)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Dystrophin-associated glycoprotein complex (GO:0016010)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Sarcolemma (GO:0042383)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	T-tubule (GO:0030315)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Caveola (GO:0005901)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Vesicle (GO:0031982)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Intercalated disc (GO:0014704)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Neuromuscular junction (GO:0031594)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O43482

Interaction Score

0.798

Q96CN9

(UniProtKB/Swiss-Prot/P) Details

GRIP and coiled-coil domain-containing protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.998	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.998	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.992	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.992	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

CCSB, BioGRID, IntAct

Interaction Source Publication:

PubMed

O43482

Interaction Score

0.798

Q86Y13

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase DZIP3

O43482

Interaction Score

0.798

Q8IYX7

(UniProtKB/Swiss-Prot/P) Details

Stabilizer of axonemal microtubules 1

O43482

Interaction Score

0.795

O76014

(UniProtKB/Swiss-Prot/P) Details

Keratin, type I cuticular Ha7

O43482

Interaction Score

0.793

Q9HCH0

(UniProtKB/Swiss-Prot/P) Details

Nck-associated protein 5-like

O43482

Interaction Score

0.793

Q8TCT0

(UniProtKB/Swiss-Prot/P) Details

Ceramide kinase

O43482

Interaction Score

0.793

Q9P2K6

(UniProtKB/Swiss-Prot/P) Details

Kelch-like protein 42

O43482

Interaction Score

0.793

P78385

(UniProtKB/Swiss-Prot/P) Details

Keratin, type II cuticular Hb3

O43482

Interaction Score

0.788

P12035

(UniProtKB/Swiss-Prot/P) Details

Keratin, type II cytoskeletal 3

O43482

Interaction Score

0.786

Q9BSW2

(UniProtKB/Swiss-Prot/P) Details

EF-hand calcium-binding domain-containing protein 4B

O43482

Interaction Score

0.776

Q8IVT2

(UniProtKB/Swiss-Prot/P) Details

Mitotic interactor and substrate of PLK1

O43482

Interaction Score

0.775

Q96JG6

(UniProtKB/Swiss-Prot/P) Details

Syndetin

O43482

Interaction Score

0.775

Q92764

(UniProtKB/Swiss-Prot/P) Details

Keratin, type I cuticular Ha5

O43482

Interaction Score

0.775

Q7Z3Y8

(UniProtKB/Swiss-Prot/P) Details

Keratin, type I cytoskeletal 27

O43482

Interaction Score

0.768

E7EWM2

(UniProtKB/TrEmbl/P) Details

Centrosomal protein of 170 kDa

O43482

Interaction Score

0.768

A0A087WWU8

(UniProtKB/TrEmbl/P) Details

Tropomyosin alpha-3 chain

O43482

Interaction Score

0.766

Q96RQ9

(UniProtKB/Swiss-Prot/P) Details

L-amino-acid oxidase

O43482

Interaction Score

0.765

Q6A162

(UniProtKB/Swiss-Prot/P) Details

Keratin, type I cytoskeletal 40

O43482

Interaction Score

0.765

Q14533

(UniProtKB/Swiss-Prot/P) Details

Keratin, type II cuticular Hb1

O43482

Interaction Score

0.752

F8W822

(UniProtKB/TrEmbl/P) Details

ARF GTPase-activating protein GIT2

O43482

Interaction Score

0.75

Q12815

(UniProtKB/Swiss-Prot/P) Details

Tastin

O43482

Interaction Score

0.728

Q1A5X7

(UniProtKB/Swiss-Prot/P) Details

Putative WASP homolog-associated protein with actin, membranes and microtubules-like protein 1

O43482

Interaction Score

0.7

Q6AHX0

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein DKFZp547L163

O43482

Interaction Score

0.7

Q6ZSJ9

(UniProtKB/Swiss-Prot/P) Details

Protein shisa-6

O43482

Interaction Score

0.7

O60220

(UniProtKB/Swiss-Prot/P) Details

Mitochondrial import inner membrane translocase subunit Tim8 A

O43482

Interaction Score

0.7

P10606

(UniProtKB/Swiss-Prot/P) Details

Cytochrome c oxidase subunit 5B, mitochondrial

O43482

Interaction Score

0.64

A4D0Z4

(UniProtKB/TrEmbl/P) Details

GRIP and coiled-coil domain containing 1, isoform CRA_a

O43482

Interaction Score

0.64

A0A087X0B7

(UniProtKB/TrEmbl/P) Details

Synaptosomal-associated protein 47

O43482

Interaction Score

0.64

F8VXI9

(UniProtKB/TrEmbl/P) Details

ARF GTPase-activating protein GIT2

O43482

Interaction Score

0.586

Q16623

(UniProtKB/Swiss-Prot/P) Details

Syntaxin-1A

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.991	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	0.51	Unknown: traceable author statement	GO	PubMed
Nucleus	Nuclear membrane (GO:0031965)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.991	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Acrosomal vesicle (GO:0001669)	0.991	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Synaptic vesicle (GO:0008021)	0.991	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Secretory-pathway	Integral to synaptic vesicle membrane (GO:0030285)	0.991	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Actomyosin (GO:0042641)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Neuron projection (GO:0043005)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Postsynaptic density (GO:0014069)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Axon (GO:0030424)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Voltage-gated potassium channel complex (GO:0008076)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	SNARE complex (GO:0031201)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex (GO:0070033)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Synaptobrevin 2-SNAP-25-syntaxin-1a complex (GO:0070044)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex (GO:0070032)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Cell junction (GO:0030054)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Presynaptic active zone membrane (GO:0048787)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O43482

Interaction Score

0.56

Q68DS0

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein DKFZp781N011

O43482

Interaction Score

0.56

Q8WY44

(UniProtKB/TrEmbl/P) Details

Quaking protein 3

O43482

Interaction Score

0.56

Q9Y3L8

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein

O43482

Interaction Score

0.56

Q6FI58

(UniProtKB/TrEmbl/P) Details

G protein-coupled receptor kinase-interactor 2 isoform 4 variant

O43482

Interaction Score

0.56

Q9H1P6

(UniProtKB/Swiss-Prot/P) Details

Uncharacterized protein C20orf85

O43482

Interaction Score

0.408

Q3LI72

(UniProtKB/Swiss-Prot/P) Details

Keratin-associated protein 19-5

O43482

Interaction Score

0.408

Q52LG2

(UniProtKB/Swiss-Prot/P) Details

Keratin-associated protein 13-2

O43482

Interaction Score

0.408

Q3LI70

(UniProtKB/Swiss-Prot/P) Details

Keratin-associated protein 19-6

O43482

Interaction Score

Q59G12

(UniProtKB/TrEmbl/P) Details

Lamina-associated polypeptide 2, isoforms beta/gamma variant

O43482

Interaction Score

A0A024R1I7

(UniProtKB/TrEmbl/P) Details

Tuftelin-interacting protein 11

O43482

Interaction Score

Q75ME0

(UniProtKB/TrEmbl/P) Details

STX1A protein

O43482

Interaction Score

A0A024R2D8

(UniProtKB/TrEmbl/P) Details

Caveolin

O43482

Interaction Score

Q8TBA6

(UniProtKB/Swiss-Prot/P) Details

Golgin subfamily A member 5

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi cisterna (GO:0031985)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Secretory-pathway	Cis-Golgi network (GO:0005801)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Transport vesicle (GO:0030133)	1	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.958	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.958	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.958	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

O43482

Interaction Score

Q9GZV7

(UniProtKB/Swiss-Prot/P) Details

Hyaluronan and proteoglycan link protein 2

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O43482

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

O43482

P37198

Nuclear pore glycoprotein p62

Localizations:

Interaction Source Database:

Interaction Source Publication:

O43482

P14678

Small nuclear ribonucleoprotein-associated proteins B and B'

Localizations:

Interaction Source Database:

Interaction Source Publication:

O43482

Q8NCD3

Holliday junction recognition protein

Localizations:

Interaction Source Database:

Interaction Source Publication:

O43482

O75934

Pre-mRNA-splicing factor SPF27

Localizations:

Interaction Source Database:

Interaction Source Publication:

O43482

Q9UBB9

Tuftelin-interacting protein 11

Localizations:

Interaction Source Database:

Interaction Source Publication:

O43482

P29084

Transcription initiation factor IIE subunit beta

Localizations:

Interaction Source Database:

Interaction Source Publication:

O43482

P61244

Protein max

Localizations:

Interaction Source Database:

Interaction Source Publication:

O43482

O60341

Lysine-specific histone demethylase 1A

Localizations:

Interaction Source Database:

Interaction Source Publication:

O43482

P49450

Histone H3-like centromeric protein A

Localizations:

Interaction Source Database:

Interaction Source Publication:

O43482

O15516

Circadian locomoter output cycles protein kaput

Localizations:

Interaction Source Database:

Interaction Source Publication:

O43482

P05412

Transcription factor AP-1

Localizations:

Interaction Source Database:

Interaction Source Publication:

O43482

P0C1Z6

TCF3 fusion partner

Localizations:

Interaction Source Database:

Interaction Source Publication:

O43482