Q86UW9

Probable E3 ubiquitin-protein ligase DTX2 // UniProt Profile

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Species	H. sapiens
Number of Interactions	130 / 150
Average Interaction Score	0.835

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.996	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.996	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.996	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nuclear membrane (GO:0031965)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear membrane (GO:0031965)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Lysosome (GO:0005764)	0.996	Predicted: pTarget method	LOCATE	PubMed

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Interactions

All Details

Q86UW9

Interaction Score

Q02548

(UniProtKB/Swiss-Prot/P) Details

Paired box protein Pax-5

Q86UW9

Interaction Score

Q86Y01

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase DTX1

Q86UW9

Interaction Score

Q9NRR5

(UniProtKB/Swiss-Prot/P) Details

Ubiquilin-4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytosolic proteasome complex (GO:0031597)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear proteasome complex (GO:0031595)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.958	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.958	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Autophagic vacuole (GO:0005776)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.958	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

Q86UW9

Interaction Score

P63165

(UniProtKB/Swiss-Prot/P) Details

Small ubiquitin-related modifier 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.972	Experimental: experimental	eSLDB	PubMed
Cytosol	Nuclear stress granule (GO:0097165)	0.972	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.972	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Fibrillar center (GO:0001650)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nuclear membrane (GO:0031965)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear membrane (GO:0031965)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear envelope (GO:0005635)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nuclear pore (GO:0005643)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	PML body (GO:0016605)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	SUMO activating enzyme complex (GO:0031510)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Heterochromatin (GO:0000792)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	XY body (GO:0001741)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendrite (GO:0030425)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.996	Experimental: experimental	eSLDB	PubMed
Membrane	Voltage-gated potassium channel complex (GO:0008076)	0.996	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.996	Experimental: inferred from direct assay	GO	PubMed
Membrane	Synapse (GO:0045202)	0.996	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

Q86UW9

Interaction Score

Q14258

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin/ISG15 ligase TRIM25

Q86UW9

Interaction Score

P49736

(UniProtKB/Swiss-Prot/P) Details

DNA replication licensing factor MCM2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Chromosome (GO:0005694)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nuclear chromosome, telomeric region (GO:0000784)	1	Unknown: HDA	GO	PubMed
Nucleus	MCM complex (GO:0042555)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear origin of replication recognition complex (GO:0005664)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Chromatin (GO:0000785)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q86UW9

Interaction Score

Q7Z3K3

(UniProtKB/Swiss-Prot/P) Details

Pogo transposable element with ZNF domain

Q86UW9

Interaction Score

Q9NRA8

(UniProtKB/Swiss-Prot/P) Details

Eukaryotic translation initiation factor 4E transporter

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.997	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.997	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoplasmic mRNA processing body (GO:0000932)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.997	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.997	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nuclear speck (GO:0016607)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	PML body (GO:0016605)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

Q86UW9

Interaction Score

O43482

(UniProtKB/Swiss-Prot/P) Details

Protein Mis18-beta

Q86UW9

Interaction Score

P14652

(UniProtKB/Swiss-Prot/P) Details

Homeobox protein Hox-B2

Q86UW9

Interaction Score

Q9BQ95

(UniProtKB/Swiss-Prot/P) Details

Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

Q86UW9

Interaction Score

Q14676

(UniProtKB/Swiss-Prot/P) Details

Mediator of DNA damage checkpoint protein 1

Q86UW9

Interaction Score

Q14764

(UniProtKB/Swiss-Prot/P) Details

Major vault protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.972	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.972	Experimental: experimental	Organelle	PubMed
Nucleus	Nuclear pore (GO:0005643)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Secretory granule lumen (GO:0034774)	0.3	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.86	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	0.86	Experimental: experimental	MatrixDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q86UW9

Interaction Score

Q96RU7

(UniProtKB/Swiss-Prot/P) Details

Tribbles homolog 3

Q86UW9

Interaction Score

Q9UKT9

(UniProtKB/Swiss-Prot/P) Details

Zinc finger protein Aiolos

Q86UW9

Interaction Score

Q8HWS3

(UniProtKB/Swiss-Prot/P) Details

DNA-binding protein RFX6

Q86UW9

Interaction Score

Q93062

(UniProtKB/Swiss-Prot/P) Details

RNA-binding protein with multiple splicing

Q86UW9

Interaction Score

Q03989

(UniProtKB/Swiss-Prot/P) Details

AT-rich interactive domain-containing protein 5A

Q86UW9

Interaction Score

Q96N77

(UniProtKB/Swiss-Prot/P) Details

Zinc finger protein 641

Q86UW9

Interaction Score

Q86Y82

(UniProtKB/Swiss-Prot/P) Details

Syntaxin-12

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Endomembrane system (GO:0012505)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Pre-autophagosomal structure (GO:0000407)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Cytosol	BLOC-1 complex (GO:0031083)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.996	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Recycling endosome membrane (GO:0055038)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Early endosome membrane (GO:0031901)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Phagocytic vesicle (GO:0045335)	0.996	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.998	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.998	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Membrane raft (GO:0045121)	0.998	Experimental: inferred from direct assay	GO	PubMed
Membrane	SNARE complex (GO:0031201)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Vesicle (GO:0031982)	1	Experimental: inferred from mutant phenotype	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

Q86UW9

Interaction Score

Q9HBZ2

(UniProtKB/Swiss-Prot/P) Details

Aryl hydrocarbon receptor nuclear translocator 2

Q86UW9

Interaction Score

P28070

(UniProtKB/Swiss-Prot/P) Details

Proteasome subunit beta type-4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Proteasome complex (GO:0000502)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Proteasome core complex (GO:0005839)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Proteasome core complex, beta-subunit complex (GO:0019774)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.91	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.902	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.902	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.902	Unknown: traceable author statement	GO	PubMed
Cytosol	Intermediate filament cytoskeleton (GO:0045111)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q86UW9

Interaction Score

Q9GZT8

(UniProtKB/Swiss-Prot/P) Details

NIF3-like protein 1

Q86UW9

Interaction Score

0.999

Q15038

(UniProtKB/Swiss-Prot/P) Details

DAZ-associated protein 2

Q86UW9

Interaction Score

0.999

P57052

(UniProtKB/Swiss-Prot/P) Details

Splicing regulator RBM11

Q86UW9

Interaction Score

0.999

P31947

(UniProtKB/Swiss-Prot/P) Details

14-3-3 protein sigma

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.8	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.86	Experimental: experimental	Human Proteinpedia	PubMed
Extracellular	Extracellular space (GO:0005615)	0.3	Unknown: traceable author statement	GO	PubMed
Membrane	Membrane (GO:0016020)	0.8	Experimental: experimental	MatrixDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

Q86UW9

Interaction Score

0.999

P51668

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin-conjugating enzyme E2 D1

Q86UW9

Interaction Score

0.999

P47897

(UniProtKB/Swiss-Prot/P) Details

Glutamine--tRNA ligase

Q86UW9

Interaction Score

0.999

P62837

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin-conjugating enzyme E2 D2

Q86UW9

Interaction Score

0.999

Q15436

(UniProtKB/Swiss-Prot/P) Details

Protein transport protein Sec23A

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.999	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Endoplasmic reticulum exit site (GO:0070971)	0.999	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.999	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	ER to Golgi transport vesicle membrane (GO:0012507)	0.999	Experimental: inferred from genetic interaction	GO	PubMed
Secretory-pathway	COPII vesicle coat (GO:0030127)	0.999	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Extrinsic to membrane (GO:0019898)	0.8	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q86UW9

Interaction Score

0.999

Q14774

(UniProtKB/Swiss-Prot/P) Details

H2.0-like homeobox protein

Q86UW9

Interaction Score

0.999

Q96SF7

(UniProtKB/Swiss-Prot/P) Details

T-box transcription factor TBX15

Q86UW9

Interaction Score

0.999

Q9BVN2

(UniProtKB/Swiss-Prot/P) Details

RUN and SH3 domain-containing protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.79	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.79	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.973	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Early endosome (GO:0005769)	0.973	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.973	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Microtubule (GO:0005874)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Postsynaptic density (GO:0014069)	0.897	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.897	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Cell junction (GO:0030054)	0.897	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Postsynaptic membrane (GO:0045211)	0.897	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q86UW9

Interaction Score

0.999

Q9UM19

(UniProtKB/Swiss-Prot/P) Details

Hippocalcin-like protein 4

Q86UW9

Interaction Score

0.999

Q14192

(UniProtKB/Swiss-Prot/P) Details

Four and a half LIM domains protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.971	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.971	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.971	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.971	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.971	Unknown: traceable author statement	GO	PubMed
Cytosol	Z disc (GO:0030018)	0.971	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	M band (GO:0031430)	0.971	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	0.971	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.7	Predicted: pTarget method	LOCATE	PubMed
Membrane	Focal adhesion (GO:0005925)	0.86	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.86	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

Q86UW9

Interaction Score

0.999

Q6P597

(UniProtKB/Swiss-Prot/P) Details

Kinesin light chain 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Kinesin complex (GO:0005871)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Microtubule (GO:0005874)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Neuron projection (GO:0043005)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Ciliary rootlet (GO:0035253)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Motile cilium (GO:0031514)	0.657	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

Q86UW9

Interaction Score

0.999

O15162

(UniProtKB/Swiss-Prot/P) Details

Phospholipid scramblase 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.86	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleolus (GO:0005730)	0.992	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.96	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.992	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.992	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.992	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	1	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Membrane raft (GO:0045121)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: pTarget method	LOCATE	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.86	Unknown: HDA	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

Q86UW9

Interaction Score

0.999

P46531

(UniProtKB/Swiss-Prot/P) Details

Neurogenic locus notch homolog protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	MAML1-RBP-Jkappa- ICN1 complex (GO:0002193)	0.998	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell surface (GO:0009986)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.3	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.998	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.657	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.657	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Acrosomal vesicle (GO:0001669)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Receptor complex (GO:0043235)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Apical plasma membrane (GO:0016324)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Adherens junction (GO:0005912)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed

Q86UW9

Interaction Score

0.999

P61601

(UniProtKB/Swiss-Prot/P) Details

Neurocalcin-delta

Q86UW9

Interaction Score

0.998

Q15645

(UniProtKB/Swiss-Prot/P) Details

Pachytene checkpoint protein 2 homolog

Q86UW9

Interaction Score

0.997

Q8N9I9

(UniProtKB/Swiss-Prot/P) Details

Probable E3 ubiquitin-protein ligase DTX3

Q86UW9

Interaction Score

0.997

Q96F45

(UniProtKB/Swiss-Prot/P) Details

Zinc finger protein 503

Q86UW9

Interaction Score

0.997

Q9H6L4

(UniProtKB/Swiss-Prot/P) Details

Armadillo repeat-containing protein 7

Q86UW9

Interaction Score

0.997

Q6PIY7

(UniProtKB/Swiss-Prot/P) Details

Poly(A) RNA polymerase GLD2

Q86UW9

Interaction Score

0.997

Q9BYV2

(UniProtKB/Swiss-Prot/P) Details

Tripartite motif-containing protein 54

Q86UW9

Interaction Score

0.997

Q6NX45

(UniProtKB/Swiss-Prot/P) Details

Zinc finger protein 774

Q86UW9

Interaction Score

0.996

O14964

(UniProtKB/Swiss-Prot/P) Details

Hepatocyte growth factor-regulated tyrosine kinase substrate

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endosome (GO:0005768)	1	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endosome (GO:0005768)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Early endosome (GO:0005769)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Early endosome membrane (GO:0031901)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Multivesicular body membrane (GO:0032585)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	ESCRT-0 complex (GO:0033565)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Lysosome (GO:0005764)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Lysosome (GO:0005764)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.8	Experimental: experimental	eSLDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q86UW9

Interaction Score

0.996

Q9NZD8

(UniProtKB/Swiss-Prot/P) Details

Maspardin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.996	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.996	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endosome membrane (GO:0010008)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Trans-Golgi network transport vesicle (GO:0030140)	0.996	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.8	Experimental: experimental	eSLDB	PubMed
Cytosol	Vesicle (GO:0031982)	1	Experimental: experimental	eSLDB	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

Q86UW9

Interaction Score

0.996

P84074

(UniProtKB/Swiss-Prot/P) Details

Neuron-specific calcium-binding protein hippocalcin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Perikaryon (GO:0043204)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Neuronal cell body membrane (GO:0032809)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Dendrite cytoplasm (GO:0032839)	0.928	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendritic spine head (GO:0044327)	0.928	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendrite membrane (GO:0032590)	0.928	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Axon (GO:0030424)	0.928	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Extrinsic to membrane (GO:0019898)	0.928	Predicted: inferred from sequence or structural similarity	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q86UW9

Interaction Score

0.996

Q15654

(UniProtKB/Swiss-Prot/P) Details

Thyroid receptor-interacting protein 6

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.997	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.997	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.997	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.997	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Interleukin-1 receptor complex (GO:0045323)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

Q86UW9

Interaction Score

0.994

Q15437

(UniProtKB/Swiss-Prot/P) Details

Protein transport protein Sec23B

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Endomembrane system (GO:0012505)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.931	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.931	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.931	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	COPII vesicle coat (GO:0030127)	0.931	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

Q86UW9

Interaction Score

0.994

Q8IVS8

(UniProtKB/Swiss-Prot/P) Details

Glycerate kinase

Q86UW9

Interaction Score

0.993

Q9H8W4

(UniProtKB/Swiss-Prot/P) Details

Pleckstrin homology domain-containing family F member 2

Q86UW9

Interaction Score

0.992

Q8WWY6

(UniProtKB/Swiss-Prot/P) Details

Methyl-CpG-binding domain protein 3-like 1

Q86UW9

Interaction Score

0.991

Q6ZNG0

(UniProtKB/Swiss-Prot/P) Details

Zinc finger protein 620

Q86UW9

Interaction Score

0.991

P61077

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin-conjugating enzyme E2 D3

Q86UW9

Interaction Score

0.99

Q9UFD9

(UniProtKB/Swiss-Prot/P) Details

RIMS-binding protein 3A

Q86UW9

Interaction Score

0.988

P62166

(UniProtKB/Swiss-Prot/P) Details

Neuronal calcium sensor 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.992	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.992	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.992	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.853	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.853	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Dense core granule (GO:0031045)	0.853	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendrite (GO:0030425)	0.99	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Postsynaptic density (GO:0014069)	0.99	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.99	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.99	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Cell junction (GO:0030054)	0.99	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Postsynaptic membrane (GO:0045211)	0.99	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

Q86UW9

Interaction Score

0.988

Q8TBB1

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase LNX

Q86UW9

Interaction Score

0.988

Q59F94

(UniProtKB/TrEmbl/P) Details

Ataxin-1 ubiquitin-like interacting protein variant

Q86UW9

Interaction Score

0.987

Q9BQY4

(UniProtKB/Swiss-Prot/P) Details

Rhox homeobox family member 2

Q86UW9

Interaction Score

0.987

Q6P1W5

(UniProtKB/Swiss-Prot/P) Details

Uncharacterized protein C1orf94

Q86UW9

Interaction Score

0.987

Q5JUK2

(UniProtKB/Swiss-Prot/P) Details

Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1

Q86UW9

Interaction Score

0.987

Q96H86

(UniProtKB/Swiss-Prot/P) Details

Zinc finger protein 764

Q86UW9

Interaction Score

0.986

Q4VC12

(UniProtKB/Swiss-Prot/P) Details

Putative protein MSS51 homolog, mitochondrial

Q86UW9

Interaction Score

0.986

Q08379

(UniProtKB/Swiss-Prot/P) Details

Golgin subfamily A member 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Endoplasmic reticulum-Golgi intermediate compartment membrane (GO:0033116)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi cisterna membrane (GO:0032580)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Golgi cis cisterna (GO:0000137)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Cis-Golgi network (GO:0005801)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	ER to Golgi transport vesicle (GO:0030134)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Cytosol	Mitotic spindle (GO:0072686)	0.958	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Spindle pole (GO:0000922)	0.958	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Microtubule (GO:0005874)	0.958	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.8	Experimental: experimental	eSLDB	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

Q86UW9

Interaction Score

0.986

O43521

(UniProtKB/Swiss-Prot/P) Details

Bcl-2-like protein 11

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Mitochondrion	Bcl-2 family protein complex (GO:0097136)	0.853	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Endomembrane system (GO:0012505)	0.956	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.956	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.956	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytosol (GO:0005829)	0.956	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.853	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Mitochondrion	Mitochondrial outer membrane (GO:0005741)	0.853	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.958	Experimental: experimental	eSLDB	PubMed
Membrane	Extrinsic to membrane (GO:0019898)	0.958	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.958	Predicted: PAML algorithm	PA-GOSUB	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q86UW9

Interaction Score

0.985

Q96M29

(UniProtKB/Swiss-Prot/P) Details

Tektin-5

Q86UW9

Interaction Score

0.981

Q5JTJ3

(UniProtKB/Swiss-Prot/P) Details

Cytochrome c oxidase assembly factor 6 homolog

Q86UW9

Interaction Score

0.981

P49639

(UniProtKB/Swiss-Prot/P) Details

Homeobox protein Hox-A1

Q86UW9

Interaction Score

0.98

Q99932

(UniProtKB/Swiss-Prot/P) Details

Sperm-associated antigen 8

Q86UW9

Interaction Score

0.978

Q9Y2X8

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin-conjugating enzyme E2 D4

Q86UW9

Interaction Score

0.978

Q63ZY3

(UniProtKB/Swiss-Prot/P) Details

KN motif and ankyrin repeat domain-containing protein 2

Q86UW9

Interaction Score

0.969

Q96G42

(UniProtKB/Swiss-Prot/P) Details

Kelch domain-containing protein 7B

Q86UW9

Interaction Score

0.959

B4E3T4

(UniProtKB/TrEmbl/P) Details

HCG2043421, isoform CRA_c

Q86UW9

Interaction Score

0.956

Q96LI6

(UniProtKB/Swiss-Prot/P) Details

Heat shock transcription factor, Y-linked

Q86UW9

Interaction Score

0.94

Q92567

(UniProtKB/Swiss-Prot/P) Details

Protein FAM168A

Q86UW9

Interaction Score

0.939

Q6AI39

(UniProtKB/Swiss-Prot/P) Details

BRD4-interacting chromatin-remodeling complex-associated protein-like

Q86UW9

Interaction Score

0.933

P62760

(UniProtKB/Swiss-Prot/P) Details

Visinin-like protein 1

Q86UW9

Interaction Score

0.933

P19113

(UniProtKB/Swiss-Prot/P) Details

Histidine decarboxylase

Q86UW9

Interaction Score

0.909

Q96NS8

(UniProtKB/Swiss-Prot/P) Details

Putative protein CLUHP3

Q86UW9

Interaction Score

0.909

Q6ZTB9

(UniProtKB/Swiss-Prot/P) Details

Putative zinc finger protein 833

Q86UW9

Interaction Score

0.909

Q58EX7

(UniProtKB/Swiss-Prot/P) Details

Puratrophin-1

Q86UW9

Interaction Score

0.909

Q8N8P3

(UniProtKB/TrEmbl/P) Details

cDNA FLJ39075 fis, clone NT2RP7016911

Q86UW9

Interaction Score

0.907

P37235

(UniProtKB/Swiss-Prot/P) Details

Hippocalcin-like protein 1

Q86UW9

Interaction Score

0.899

Q8IUC1

(UniProtKB/Swiss-Prot/P) Details

Keratin-associated protein 11-1

Q86UW9

Interaction Score

0.86

Q5TD97

(UniProtKB/Swiss-Prot/P) Details

Four and a half LIM domains protein 5

Q86UW9

Interaction Score

0.851

Q9NXW9

(UniProtKB/Swiss-Prot/P) Details

Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4

Q86UW9

Interaction Score

0.8

C9J7K9

(UniProtKB/TrEmbl/P) Details

Phospholipid scramblase

Q86UW9

Interaction Score

0.8

Q5SWW7

(UniProtKB/Swiss-Prot/P) Details

Uncharacterized protein C10orf55

Q86UW9

Interaction Score

0.8

A0A087WVE9

(UniProtKB/TrEmbl/P) Details

Aryl hydrocarbon receptor nuclear translocator 2

Q86UW9

Interaction Score

0.797

B4DGW9

(UniProtKB/TrEmbl/P) Details

cDNA FLJ50758, moderately similar to Hippocalcin-like protein 4

Q86UW9

Interaction Score

0.797

A0A087WW00

(UniProtKB/TrEmbl/P) Details

Ubiquitin-conjugating enzyme E2 D1

Q86UW9

Interaction Score

0.797

D6RAH7

(UniProtKB/TrEmbl/P) Details

Ubiquitin-conjugating enzyme E2 D3

Q86UW9

Interaction Score

0.797

A0A2R8YFH5

(UniProtKB/TrEmbl/P) Details

Protein transport protein Sec23B

Q86UW9

Interaction Score

0.797

Q96IW7

(UniProtKB/Swiss-Prot/P) Details

Vesicle-trafficking protein SEC22a

Q86UW9

Interaction Score

0.797

Q16740

(UniProtKB/Swiss-Prot/P) Details

ATP-dependent Clp protease proteolytic subunit, mitochondrial

Q86UW9

Interaction Score

0.787

Q9P2M1

(UniProtKB/Swiss-Prot/P) Details

LRP2-binding protein

Q86UW9

Interaction Score

0.7

A1Z5I9

(UniProtKB/TrEmbl/P) Details

Mediator of DNA damage checkpoint 1 variant 1

Q86UW9

Interaction Score

0.7

Q7Z3A3

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein DKFZp686M216

Q86UW9

Interaction Score

0.7

Q86TN1

(UniProtKB/TrEmbl/P) Details

ARNT2 protein

Q86UW9

Interaction Score

0.7

Q6I9R8

(UniProtKB/TrEmbl/P) Details

FHL2 protein

Q86UW9

Interaction Score

0.697

Q9UQL0

(UniProtKB/TrEmbl/P) Details

Ubiquitin-conjugating enzyme 1 isoform

Q86UW9

Interaction Score

0.697

O75544

(UniProtKB/TrEmbl/P) Details

BDP-1 protein

Q86UW9

Interaction Score

0.697

Q6FGY1

(UniProtKB/TrEmbl/P) Details

HPCAL1 protein

Q86UW9

Interaction Score

0.697

Q6P5X5

(UniProtKB/Swiss-Prot/P) Details

UPF0545 protein C22orf39

Q86UW9

Interaction Score

0.697

A2RU56

(UniProtKB/TrEmbl/P) Details

LOC401296 protein

Q86UW9

Interaction Score

0.697

Q9H1P6

(UniProtKB/Swiss-Prot/P) Details

Uncharacterized protein C20orf85

Q86UW9

Interaction Score

0.697

Q2M3A8

(UniProtKB/Swiss-Prot/P) Details

Putative uncharacterized protein MRGPRG-AS1

Q86UW9

Interaction Score

0.697

Q6ICL0

(UniProtKB/TrEmbl/P) Details

Em:AC006547.7 protein

Q86UW9

Interaction Score

0.697

B1ATL7

(UniProtKB/Swiss-Prot/P) Details

Proline-rich protein 32

Q86UW9

Interaction Score

0.697

Q8NI60

(UniProtKB/Swiss-Prot/P) Details

Atypical kinase COQ8A, mitochondrial

Q86UW9

Interaction Score

0.51

Q69YG0

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 42

Q86UW9

Interaction Score

0.508

Q6PEX3

(UniProtKB/Swiss-Prot/P) Details

Keratin-associated protein 26-1

Q86UW9

Interaction Score

0.508

Q3SYF9

(UniProtKB/Swiss-Prot/P) Details

Keratin-associated protein 19-7

Q86UW9

Interaction Score

0.508

Q8IUB9

(UniProtKB/Swiss-Prot/P) Details

Keratin-associated protein 19-1

Q86UW9

Interaction Score

0.508

Q8IUC2

(UniProtKB/Swiss-Prot/P) Details

Keratin-associated protein 8-1

Q86UW9

Interaction Score

0.508

Q3LI76

(UniProtKB/Swiss-Prot/P) Details

Keratin-associated protein 15-1

Q86UW9

Interaction Score

0.508

Q3LI70

(UniProtKB/Swiss-Prot/P) Details

Keratin-associated protein 19-6

Q86UW9

Interaction Score

0.508

Q3LI64

(UniProtKB/Swiss-Prot/P) Details

Keratin-associated protein 6-1

Q86UW9

Interaction Score

0.299

Q8IUC3

(UniProtKB/Swiss-Prot/P) Details

Keratin-associated protein 7-1

Q86UW9

Interaction Score

Q2XQU9

(UniProtKB/TrEmbl/P) Details

FHL2 isoform 5

Q86UW9

Interaction Score

O95870

(UniProtKB/Swiss-Prot/P) Details

Protein ABHD16A

Q86UW9

Interaction Score

Q8N1F1

(UniProtKB/Swiss-Prot/P) Details

Putative uncharacterized protein LRRC75A-AS1, mitochondrial

Q86UW9

Interaction Score

Q96MT4

(UniProtKB/Swiss-Prot/P) Details

Uncharacterized protein encoded by LINC01600

Q86UW9

Interaction Score

Q49A12

(UniProtKB/TrEmbl/P) Details

ZNF85 protein

Q86UW9

Interaction Score

Q96PJ5

(UniProtKB/Swiss-Prot/P) Details

Fc receptor-like protein 4

Q86UW9

Interaction Score

Q8NA97

(UniProtKB/Swiss-Prot/P) Details

Putative uncharacterized protein FER1L6-AS1

Q86UW9

Interaction Score

Q9NV39

(UniProtKB/Swiss-Prot/P) Details

Proline-rich protein 34

Q86UW9

Interaction Score

Q8N616

(UniProtKB/Swiss-Prot/P) Details

Putative uncharacterized protein encoded by LINC00311

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Q86UW9

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

Q86UW9

Q02548

Paired box protein Pax-5

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86UW9

Q86Y01

E3 ubiquitin-protein ligase DTX1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86UW9

Q9NRR5

Ubiquilin-4

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86UW9

P63165

Small ubiquitin-related modifier 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86UW9

Q14258

E3 ubiquitin/ISG15 ligase TRIM25

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86UW9

P49736

DNA replication licensing factor MCM2

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86UW9

Q7Z3K3

Pogo transposable element with ZNF domain

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86UW9

Q9NRA8

Eukaryotic translation initiation factor 4E transporter

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86UW9

O43482

Protein Mis18-beta

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86UW9

P14652

Homeobox protein Hox-B2

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86UW9

Q9BQ95

Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86UW9

Q14676

Mediator of DNA damage checkpoint protein 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q86UW9