Q9H0A8

COMM domain-containing protein 4 // UniProt Profile

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Species	H. sapiens
Number of Interactions	66 / 88
Average Interaction Score	0.892

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.988	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.988	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.988	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	0.958	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.958	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.958	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Plasma membrane (GO:0005886)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

Q9H0A8

Interaction Score

Q9HC77

(UniProtKB/Swiss-Prot/P) Details

Centromere protein J

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.988	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cilium basal body (GO:0036064)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Centriole (GO:0005814)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Gamma-tubulin small complex (GO:0008275)	1	Unknown: non-traceable author statement	GO	PubMed
Cytosol	Microtubule (GO:0005874)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

Q9H0A8

Interaction Score

Q15154

(UniProtKB/Swiss-Prot/P) Details

Pericentriolar material 1 protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Apical part of cell (GO:0045177)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nuclear membrane (GO:0031965)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear membrane (GO:0031965)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.999	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Cilium basal body (GO:0036064)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Pericentriolar material (GO:0000242)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Centriolar satellite (GO:0034451)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centriole (GO:0005814)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Ciliary transition zone (GO:0035869)	0.86	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.86	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

Q9H0A8

Interaction Score

P19838

(UniProtKB/Swiss-Prot/P) Details

Nuclear factor NF-kappa-B p105 subunit

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	I-kappaB/NF-kappaB complex (GO:0033256)	0.998	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.8	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Secretory granule lumen (GO:0034774)	0.3	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.3	Unknown: traceable author statement	GO	PubMed
Membrane	Membrane (GO:0016020)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

Q9H0A8

Interaction Score

P26196

(UniProtKB/Swiss-Prot/P) Details

Probable ATP-dependent RNA helicase DDX6

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	RNA-induced silencing complex (GO:0016442)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasmic stress granule (GO:0010494)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Chromatoid body (GO:0033391)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasmic mRNA processing body (GO:0000932)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Unknown: inferred from electronic annotation	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.987	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.987	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleolus (GO:0005730)	0.987	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Heterochromatin (GO:0000792)	0.987	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Outer dense fiber (GO:0001520)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Sperm annulus (GO:0097227)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.657	Unknown: HDA	GO	PubMed
Membrane	Cell-cell adherens junction (GO:0005913)	0.657	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9H0A8

Interaction Score

Q68EM7

(UniProtKB/Swiss-Prot/P) Details

Rho GTPase-activating protein 17

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.996	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.996	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.996	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Tight junction (GO:0005923)	0.51	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9H0A8

Interaction Score

Q9P000

(UniProtKB/Swiss-Prot/P) Details

COMM domain-containing protein 9

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.988	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	0.988	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.972	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.972	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Secretory granule lumen (GO:0034774)	0.972	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.3	Unknown: traceable author statement	GO	PubMed
Membrane	Membrane (GO:0016020)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9H0A8

Interaction Score

0.999

O60566

(UniProtKB/Swiss-Prot/P) Details

Mitotic checkpoint serine/threonine-protein kinase BUB1 beta

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Ubiquitin ligase complex (GO:0000151)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Anaphase-promoting complex (GO:0005680)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Spindle midzone (GO:0051233)	1	Unknown: non-traceable author statement	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Chromosome (GO:0005694)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Condensed nuclear chromosome kinetochore (GO:0000778)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Condensed chromosome kinetochore (GO:0000777)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Condensed chromosome outer kinetochore (GO:0000940)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Kinetochore (GO:0000776)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

Q9H0A8

Interaction Score

0.999

Q9NPD3

(UniProtKB/Swiss-Prot/P) Details

Exosome complex component RRP41

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Unknown: non-traceable author statement	GO	PubMed
Cytosol	Exosome (RNase complex) (GO:0000178)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasmic exosome (RNase complex) (GO:0000177)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nuclear exosome (RNase complex) (GO:0000176)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Intermediate filament cytoskeleton (GO:0045111)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intermediate filament cytoskeleton (GO:0045111)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Transcriptionally active chromatin (GO:0035327)	1	Experimental: inferred from mutant phenotype	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9H0A8

Interaction Score

0.999

Q04206

(UniProtKB/Swiss-Prot/P) Details

Transcription factor p65

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	I-kappaB/NF-kappaB complex (GO:0033256)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Transcription factor complex (GO:0005667)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear chromatin (GO:0000790)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

Q9H0A8

Interaction Score

0.999

Q8N668

(UniProtKB/Swiss-Prot/P) Details

COMM domain-containing protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cul2-RING ubiquitin ligase complex (GO:0031462)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Recycling endosome (GO:0055037)	0.972	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Early endosome (GO:0005769)	0.972	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endosome membrane (GO:0010008)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed

Q9H0A8

Interaction Score

0.999

A5D8V7

(UniProtKB/Swiss-Prot/P) Details

Coiled-coil domain-containing protein 151

Q9H0A8

Interaction Score

0.999

Q01201

(UniProtKB/Swiss-Prot/P) Details

Transcription factor RelB

Q9H0A8

Interaction Score

0.999

Q9Y5K8

(UniProtKB/Swiss-Prot/P) Details

V-type proton ATPase subunit D

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.91	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Vacuolar membrane (GO:0005774)	0.999	Experimental: experimental	Organelle	PubMed
Cytosol	Lysosomal membrane (GO:0005765)	0.999	Unknown: HDA	GO	PubMed
Cytosol	Centrosome (GO:0005813)	0.999	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cilium (GO:0005929)	0.994	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.994	Experimental: inferred from direct assay	GO	PubMed
Membrane	Proton-transporting V-type ATPase complex (GO:0033176)	0.994	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.994	Unknown: traceable author statement	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.999	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9H0A8

Interaction Score

0.999

Q9Y5K5

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin carboxyl-terminal hydrolase isozyme L5

Q9H0A8

Interaction Score

0.999

P54727

(UniProtKB/Swiss-Prot/P) Details

UV excision repair protein RAD23 homolog B

Q9H0A8

Interaction Score

0.999

Q96S44

(UniProtKB/Swiss-Prot/P) Details

EKC/KEOPS complex subunit TP53RK

Q9H0A8

Interaction Score

0.999

Q13868

(UniProtKB/Swiss-Prot/P) Details

Exosome complex component RRP4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Exosome (RNase complex) (GO:0000178)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasmic exosome (RNase complex) (GO:0000177)	0.992	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.992	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear exosome (RNase complex) (GO:0000176)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9H0A8

Interaction Score

0.999

Q14258

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin/ISG15 ligase TRIM25

Q9H0A8

Interaction Score

0.999

Q9BTE3

(UniProtKB/Swiss-Prot/P) Details

Mini-chromosome maintenance complex-binding protein

Q9H0A8

Interaction Score

0.999

Q567U6

(UniProtKB/Swiss-Prot/P) Details

Coiled-coil domain-containing protein 93

Q9H0A8

Interaction Score

0.999

Q9BWU1

(UniProtKB/Swiss-Prot/P) Details

Cyclin-dependent kinase 19

Q9H0A8

Interaction Score

0.999

Q9NX08

(UniProtKB/Swiss-Prot/P) Details

COMM domain-containing protein 8

Q9H0A8

Interaction Score

0.998

P08237

(UniProtKB/Swiss-Prot/P) Details

ATP-dependent 6-phosphofructokinase, muscle type

Q9H0A8

Interaction Score

0.998

Q14186

(UniProtKB/Swiss-Prot/P) Details

Transcription factor Dp-1

Q9H0A8

Interaction Score

0.998

Q9GZQ3

(UniProtKB/Swiss-Prot/P) Details

COMM domain-containing protein 5

Q9H0A8

Interaction Score

0.997

O75665

(UniProtKB/Swiss-Prot/P) Details

Oral-facial-digital syndrome 1 protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cilium basal body (GO:0036064)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centriolar satellite (GO:0034451)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Centriole (GO:0005814)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cilium (GO:0005929)	0.86	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.86	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

Q9H0A8

Interaction Score

0.996

Q96NL6

(UniProtKB/Swiss-Prot/P) Details

Sodium channel and clathrin linker 1

Q9H0A8

Interaction Score

0.996

Q8NBT0

(UniProtKB/Swiss-Prot/P) Details

POC1 centriolar protein homolog A

Q9H0A8

Interaction Score

0.996

O60826

(UniProtKB/Swiss-Prot/P) Details

Coiled-coil domain-containing protein 22

Q9H0A8

Interaction Score

0.994

Q9NQP4

(UniProtKB/Swiss-Prot/P) Details

Prefoldin subunit 4

Q9H0A8

Interaction Score

0.993

O75663

(UniProtKB/Swiss-Prot/P) Details

TIP41-like protein

Q9H0A8

Interaction Score

0.993

Q01813

(UniProtKB/Swiss-Prot/P) Details

ATP-dependent 6-phosphofructokinase, platelet type

Q9H0A8

Interaction Score

0.992

Q86VX2

(UniProtKB/Swiss-Prot/P) Details

COMM domain-containing protein 7

Q9H0A8

Interaction Score

0.991

Q8TCE6

(UniProtKB/Swiss-Prot/P) Details

Protein FAM45A

Q9H0A8

Interaction Score

0.988

Q86X83

(UniProtKB/Swiss-Prot/P) Details

COMM domain-containing protein 2

Q9H0A8

Interaction Score

0.988

Q9UBQ0

(UniProtKB/Swiss-Prot/P) Details

Vacuolar protein sorting-associated protein 29

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Retromer complex (GO:0030904)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Retromer complex, inner shell (GO:0030906)	1	Unknown: non-traceable author statement	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.986	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.986	Experimental: experimental	Human Proteinpedia	PubMed
Secretory-pathway	Early endosome (GO:0005769)	0.986	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Late endosome (GO:0005770)	0.986	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endosome membrane (GO:0010008)	0.986	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9H0A8

Interaction Score

0.988

Q9Y6G5

(UniProtKB/Swiss-Prot/P) Details

COMM domain-containing protein 10

Q9H0A8

Interaction Score

0.987

O75461

(UniProtKB/Swiss-Prot/P) Details

Transcription factor E2F6

Q9H0A8

Interaction Score

0.987

Q8NDH3

(UniProtKB/Swiss-Prot/P) Details

Probable aminopeptidase NPEPL1

Q9H0A8

Interaction Score

0.987

P52565

(UniProtKB/Swiss-Prot/P) Details

Rho GDP-dissociation inhibitor 1

Q9H0A8

Interaction Score

0.982

F6VUX8

(UniProtKB/TrEmbl/P) Details

Centromere protein J

Q9H0A8

Interaction Score

0.977

A6NF31

(UniProtKB/TrEmbl/P) Details

Oral-facial-digital syndrome 1 protein

Q9H0A8

Interaction Score

0.976

P50225

(UniProtKB/Swiss-Prot/P) Details

Sulfotransferase 1A1

Q9H0A8

Interaction Score

0.973

Q9UBI1

(UniProtKB/Swiss-Prot/P) Details

COMM domain-containing protein 3

Q9H0A8

Interaction Score

0.969

Q53YM3

(UniProtKB/TrEmbl/P) Details

E2F transcription factor 6, isoform CRA_d

Q9H0A8

Interaction Score

0.969

Q6Q9Z5

(UniProtKB/TrEmbl/P) Details

E2F6 splice variant f

Q9H0A8

Interaction Score

0.958

Q969R5

(UniProtKB/Swiss-Prot/P) Details

Lethal(3)malignant brain tumor-like protein 2

Q9H0A8

Interaction Score

0.951

D6R992

(UniProtKB/TrEmbl/P) Details

Transcription factor RelB

Q9H0A8

Interaction Score

0.951

E9PJ95

(UniProtKB/TrEmbl/P) Details

COMM domain-containing protein 9

Q9H0A8

Interaction Score

0.948

D6RBA6

(UniProtKB/TrEmbl/P) Details

Sodium channel and clathrin linker 1

Q9H0A8

Interaction Score

0.948

F8VXU5

(UniProtKB/TrEmbl/P) Details

Vacuolar protein sorting-associated protein 29

Q9H0A8

Interaction Score

0.928

Q7Z4G1

(UniProtKB/Swiss-Prot/P) Details

COMM domain-containing protein 6

Q9H0A8

Interaction Score

0.898

Q53FR9

(UniProtKB/TrEmbl/P) Details

COMM domain containing 9 variant

Q9H0A8

Interaction Score

0.805

Q7Z3J2

(UniProtKB/Swiss-Prot/P) Details

UPF0505 protein C16orf62

Q9H0A8

Interaction Score

0.79

A0A087X0W8

(UniProtKB/TrEmbl/P) Details

Transcription factor p65

Q9H0A8

Interaction Score

0.79

J3QQX2

(UniProtKB/TrEmbl/P) Details

Rho GDP-dissociation inhibitor 1

Q9H0A8

Interaction Score

0.766

Q9HBV2

(UniProtKB/Swiss-Prot/P) Details

Sperm acrosome membrane-associated protein 1

Q9H0A8

Interaction Score

0.766

K7EN59

(UniProtKB/TrEmbl/P) Details

Coiled-coil domain-containing protein 151

Q9H0A8

Interaction Score

0.766

Q5RI15

(UniProtKB/Swiss-Prot/P) Details

Cytochrome c oxidase assembly protein COX20, mitochondrial

Q9H0A8

Interaction Score

0.757

O14972

(UniProtKB/Swiss-Prot/P) Details

Down syndrome critical region protein 3

Q9H0A8

Interaction Score

0.671

E7EWW0

(UniProtKB/TrEmbl/P) Details

VPS35 endosomal protein sorting factor-like

Q9H0A8

Interaction Score

0.465

D6RJ90

(UniProtKB/TrEmbl/P) Details

COMM domain containing 10, isoform CRA_b

Q9H0A8

Interaction Score

F5H7K1

(UniProtKB/TrEmbl/P) Details

VPS35 endosomal protein sorting factor-like

Q9H0A8

Interaction Score

A8MTY9

(UniProtKB/TrEmbl/P) Details

VPS26 endosomal protein sorting factor C

Q9H0A8

Interaction Score

A8MY26

(UniProtKB/TrEmbl/P) Details

VPS26 endosomal protein sorting factor C

Q9H0A8

Interaction Score

A0A2R8Y891

(UniProtKB/TrEmbl/P) Details

ATP-dependent 6-phosphofructokinase

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Q9H0A8

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

Q9H0A8

Q9HC77

Centromere protein J

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9H0A8

Q15154

Pericentriolar material 1 protein

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9H0A8

P19838

Nuclear factor NF-kappa-B p105 subunit

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9H0A8

P26196

Probable ATP-dependent RNA helicase DDX6

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9H0A8

Q68EM7

Rho GTPase-activating protein 17

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9H0A8

Q9P000

COMM domain-containing protein 9

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9H0A8

O60566

Mitotic checkpoint serine/threonine-protein kinase BUB1 beta

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9H0A8

Q9NPD3

Exosome complex component RRP41

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9H0A8

Q04206

Transcription factor p65

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9H0A8

Q8N668

COMM domain-containing protein 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9H0A8

A5D8V7

Coiled-coil domain-containing protein 151

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9H0A8

Q01201

Transcription factor RelB

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9H0A8