O75461

Transcription factor E2F6    //   UniProt Profile 

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Species

 H. sapiens

Number of Interactions

 96 / 119

Average Interaction Score

 0.864

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus MLL1 complex (GO:0071339) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus RNA polymerase II transcription factor complex (GO:0090575) 1 Experimental: inferred from direct assay GO PubMed 

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.


Interactions

All Details

O75461

Interaction Score
1

P03372

(UniProtKB/Swiss-Prot/P) Details

Estrogen receptor

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
N/A Transcriptional preinitiation complex (GO:0097550) 0.8 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.992 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.992 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.992 Unknown: traceable author statement GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.992 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Unknown: traceable author statement GO PubMed 
Nucleus Macromolecular complex (GO:0032991) 1 Experimental: inferred from mutant phenotype GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Chromosome (GO:0005694) 1 Experimental: experimental Organelle PubMed 
Nucleus Nuclear chromatin (GO:0000790) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Transcriptionally active chromatin (GO:0035327) 1 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.902 Unknown: non-traceable author statement GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.902 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.902 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75461

Interaction Score
1

Q99496

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase RING2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Ubiquitin ligase complex (GO:0000151) 0.94 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.94 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nuclear body (GO:0016604) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear body (GO:0016604) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus MLL1 complex (GO:0071339) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus PcG protein complex (GO:0031519) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus PRC1 complex (GO:0035102) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Euchromatin (GO:0000791) 1 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Sex chromatin (GO:0001739) 1 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed , PubMed 

O75461

Interaction Score
1

Q13547

(UniProtKB/Swiss-Prot/P) Details

Histone deacetylase 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Neuronal cell body (GO:0043025) 0.902 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.902 Unknown: traceable author statement GO PubMed 
Cytosol Cytosol (GO:0005829) 0.902 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus NuRD complex (GO:0016581) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Transcription factor complex (GO:0005667) 1 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Macromolecular complex (GO:0032991) 1 Unknown: HDA GO PubMed 
Nucleus Histone deacetylase complex (GO:0000118) 1 Unknown: traceable author statement GO PubMed 
Nucleus Sin3 complex (GO:0016580) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear chromatin (GO:0000790) 1 Unknown: HDA GO PubMed 
Nucleus Chromatin (GO:0000785) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Heterochromatin (GO:0000792) 1 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

O75461

Interaction Score
1

Q01094

(UniProtKB/Swiss-Prot/P) Details

Transcription factor E2F1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Mitochondrion Mitochondrion (GO:0005739) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Rb-E2F complex (GO:0035189) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Macromolecular complex (GO:0032991) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Centrosome (GO:0005813) 0.96 Experimental: inferred from direct assay GO PubMed 
Cytosol Centrosome (GO:0005813) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nuclear chromatin (GO:0000790) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed 

O75461

Interaction Score
1

Q03164

(UniProtKB/Swiss-Prot/P) Details

Histone-lysine N-methyltransferase 2A

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.96 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Histone methyltransferase complex (GO:0035097) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus MLL1 complex (GO:0071339) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75461

Interaction Score
1

Q06587

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase RING1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.96 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nuclear speck (GO:0016607) 1 Unknown: inferred from electronic annotation GO PubMed 
Nucleus PcG protein complex (GO:0031519) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus PRC1 complex (GO:0035102) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Sex chromatin (GO:0001739) 1 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed , PubMed 

O75461

Interaction Score
1

P35226

(UniProtKB/Swiss-Prot/P) Details

Polycomb complex protein BMI-1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Ubiquitin ligase complex (GO:0000151) 0.992 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.992 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.992 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleolus (GO:0005730) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Unknown: traceable author statement GO PubMed 
Nucleus Nuclear body (GO:0016604) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear body (GO:0016604) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus PcG protein complex (GO:0031519) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus PRC1 complex (GO:0035102) 1 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.7 Predicted: pTarget method LOCATE PubMed 

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed 

O75461

Interaction Score
1

P61244

(UniProtKB/Swiss-Prot/P) Details

Protein max

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.94 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.86 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Unknown: traceable author statement GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus PML body (GO:0016605) 1 Unknown: inferred from electronic annotation GO PubMed 
Nucleus MLL1 complex (GO:0071339) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus RNA polymerase II transcription factor complex (GO:0090575) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Protein-DNA complex (GO:0032993) 1 Experimental: inferred from mutant phenotype GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.94 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nuclear chromatin (GO:0000790) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Dendrite (GO:0030425) 0.3 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed , PubMed 

O75461

Interaction Score
1

Q13185

(UniProtKB/Swiss-Prot/P) Details

Chromobox protein homolog 3

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nuclear inner membrane (GO:0005637) 1 Unknown: non-traceable author statement GO PubMed 
Nucleus Nuclear envelope (GO:0005635) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Unknown: traceable author statement GO PubMed 
Nucleus Nuclear body (GO:0016604) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Spindle (GO:0005819) 0.8 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear chromosome, telomeric region (GO:0000784) 1 Unknown: HDA GO PubMed 
Nucleus Nuclear euchromatin (GO:0005719) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear heterochromatin (GO:0005720) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear centromeric heterochromatin (GO:0031618) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Nucleus Chromatin (GO:0000785) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Chromosome, centromeric region (GO:0000775) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Condensed chromosome, centromeric region (GO:0000779) 1 Predicted: inferred from sequence or structural similarity GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed , PubMed 

O75461

Interaction Score
1

P83916

(UniProtKB/Swiss-Prot/P) Details

Chromobox protein homolog 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Female pronucleus (GO:0001939) 1 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Male pronucleus (GO:0001940) 1 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Unknown: traceable author statement GO PubMed 
Nucleus Nuclear body (GO:0016604) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Spindle (GO:0005819) 0.8 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear chromosome, telomeric region (GO:0000784) 1 Unknown: HDA GO PubMed 
Nucleus Nuclear heterochromatin (GO:0005720) 1 Unknown: traceable author statement GO PubMed 
Nucleus Chromatin (GO:0000785) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Centromeric heterochromatin (GO:0005721) 1 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Chromocenter (GO:0010369) 1 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Chromosome, centromeric region (GO:0000775) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

O75461

Interaction Score
1

P61964

(UniProtKB/Swiss-Prot/P) Details

WD repeat-containing protein 5

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Histone methyltransferase complex (GO:0035097) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus MLL3/4 complex (GO:0044666) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Set1C/COMPASS complex (GO:0048188) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus MLL1 complex (GO:0071339) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Histone acetyltransferase complex (GO:0000123) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Ada2/Gcn5/Ada3 transcription activator complex (GO:0005671) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cilium basal body (GO:0036064) 0.7 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed , PubMed 

O75461

Interaction Score
1

Q92769

(UniProtKB/Swiss-Prot/P) Details

Histone deacetylase 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.3 Unknown: traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Unknown: traceable author statement GO PubMed 
Nucleus NuRD complex (GO:0016581) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Macromolecular complex (GO:0032991) 1 Unknown: HDA GO PubMed 
Nucleus ESC/E(Z) complex (GO:0035098) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Sin3 complex (GO:0016580) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear chromatin (GO:0000790) 1 Unknown: HDA GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

O75461

Interaction Score
1

Q9HC52

(UniProtKB/Swiss-Prot/P) Details

Chromobox protein homolog 8

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Human Proteinpedia PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleolus (GO:0005730) 1 Experimental: experimental Human Proteinpedia PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus PcG protein complex (GO:0031519) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus PRC1 complex (GO:0035102) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear chromatin (GO:0000790) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Heterochromatin (GO:0000792) 1 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

O75461

Interaction Score
1

Q9H2F5

(UniProtKB/Swiss-Prot/P) Details

Enhancer of polycomb homolog 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nuclear membrane (GO:0031965) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Piccolo NuA4 histone acetyltransferase complex (GO:0032777) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus NuA4 histone acetyltransferase complex (GO:0035267) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

HPRD, BioGRID

Interaction Source Publication:

PubMed 

O75461

Interaction Score
1

Q9H4L7

(UniProtKB/Swiss-Prot/P) Details

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nuclear matrix (GO:0016363) 1 Unknown: non-traceable author statement GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Site of double-strand break (GO:0035861) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear replication fork (GO:0043596) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Heterochromatin (GO:0000792) 1 Predicted: inferred from sequence or structural similarity GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75461

Interaction Score
1

Q14186

(UniProtKB/Swiss-Prot/P) Details

Transcription factor Dp-1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.96 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus RNA polymerase II transcription factor complex (GO:0090575) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed , PubMed 

O75461

Interaction Score
1

Q92800

(UniProtKB/Swiss-Prot/P) Details

Histone-lysine N-methyltransferase EZH1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Human Proteinpedia PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleolus (GO:0005730) 1 Experimental: experimental Human Proteinpedia PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus ESC/E(Z) complex (GO:0035098) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

HPRD, BioGRID

Interaction Source Publication:

PubMed 

O75461

Interaction Score
1

P35227

(UniProtKB/Swiss-Prot/P) Details

Polycomb group RING finger protein 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Unknown: traceable author statement GO PubMed 
Nucleus Nuclear body (GO:0016604) 1 Unknown: inferred from electronic annotation GO PubMed 
Nucleus PcG protein complex (GO:0031519) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus PRC1 complex (GO:0035102) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear chromatin (GO:0000790) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Sex chromatin (GO:0001739) 1 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

O75461

Interaction Score
1

O75530

(UniProtKB/Swiss-Prot/P) Details

Polycomb protein EED

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.94 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytosol (GO:0005829) 0.94 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Unknown: non-traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Pronucleus (GO:0045120) 1 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus ESC/E(Z) complex (GO:0035098) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Sex chromatin (GO:0001739) 1 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75461

Interaction Score
1

Q15910

(UniProtKB/Swiss-Prot/P) Details

Histone-lysine N-methyltransferase EZH2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Pronucleus (GO:0045120) 1 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Unknown: traceable author statement GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus ESC/E(Z) complex (GO:0035098) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear chromatin (GO:0000790) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

HPRD, BioGRID

Interaction Source Publication:

PubMed , PubMed 

O75461

Interaction Score
1

Q969R5

(UniProtKB/Swiss-Prot/P) Details

Lethal(3)malignant brain tumor-like protein 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Human Proteinpedia PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Unknown: traceable author statement GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed , PubMed 

O75461

Interaction Score
1

Q9Y2G2

(UniProtKB/Swiss-Prot/P) Details

Caspase recruitment domain-containing protein 8

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol NLRP3 inflammasome complex (GO:0072559) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Macromolecular complex (GO:0032991) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75461

Interaction Score
1

Q15326

(UniProtKB/Swiss-Prot/P) Details

Zinc finger MYND domain-containing protein 11

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Chromosome (GO:0005694) 1 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

HPRD, BioGRID

Interaction Source Publication:

PubMed 

O75461

Interaction Score
1

O14686

(UniProtKB/Swiss-Prot/P) Details

Histone-lysine N-methyltransferase 2D

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.94 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytosol (GO:0005829) 0.94 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 1 Unknown: non-traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Unknown: traceable author statement GO PubMed 
Nucleus Histone methyltransferase complex (GO:0035097) 1 Predicted: inferred from physical interaction GO PubMed 
Nucleus MLL3/4 complex (GO:0044666) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75461

Interaction Score
1

Q13127

(UniProtKB/Swiss-Prot/P) Details

RE1-silencing transcription factor

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytosol (GO:0005829) 0.86 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Unknown: traceable author statement GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Transcriptional repressor complex (GO:0017053) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

O75461

Interaction Score
1

Q8N344

(UniProtKB/Swiss-Prot/P) Details

Mesoderm induction early response protein 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.988 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.988 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.988 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Macromolecular complex (GO:0032991) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75461

Interaction Score
1

Q14188

(UniProtKB/Swiss-Prot/P) Details

Transcription factor Dp-2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Unknown: traceable author statement GO PubMed 
Nucleus RNA polymerase II transcription factor complex (GO:0090575) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed , PubMed 

O75461

Interaction Score
1

P41229

(UniProtKB/Swiss-Prot/P) Details

Lysine-specific demethylase 5C

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.96 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID, DIP, IntAct

Interaction Source Publication:

PubMed , PubMed 

O75461

Interaction Score
1

Q05195

(UniProtKB/Swiss-Prot/P) Details

Max dimerization protein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.86 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.86 Unknown: unspecified method The Human Protein Atlas PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.86 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.86 Unknown: unspecified method The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Unknown: traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Unknown: unspecified method The Human Protein Atlas PubMed 
Nucleus Nuclear chromatin (GO:0000790) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75461

Interaction Score
1

Q8IY57

(UniProtKB/Swiss-Prot/P) Details

YY1-associated factor 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.8 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed , PubMed 

O75461

Interaction Score
1

P17980

(UniProtKB/Swiss-Prot/P) Details

26S proteasome regulatory subunit 6A

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytoplasmic mRNA processing body (GO:0000932) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Unknown: traceable author statement GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Proteasome complex (GO:0000502) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosolic proteasome complex (GO:0031597) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Proteasome accessory complex (GO:0022624) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Proteasome regulatory particle, base subcomplex (GO:0008540) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Unknown: HDA GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nuclear proteasome complex (GO:0031595) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Unknown: traceable author statement GO PubMed 
Secretory-pathway Secretory granule lumen (GO:0034774) 0.3 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.86 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.86 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.86 Unknown: HDA GO PubMed 
Membrane Membrane (GO:0016020) 0.86 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75461

Interaction Score
1

Q8N488

(UniProtKB/Swiss-Prot/P) Details

RING1 and YY1-binding protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus PcG protein complex (GO:0031519) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed 

O75461

Interaction Score
1

Q96JM7

(UniProtKB/Swiss-Prot/P) Details

Lethal(3)malignant brain tumor-like protein 3

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleolus (GO:0005730) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleolus (GO:0005730) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

DIP, IntAct

Interaction Source Publication:

PubMed 

O75461

Interaction Score
1

Q8IWI9

(UniProtKB/Swiss-Prot/P) Details

MAX gene-associated protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.94 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.999 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.999 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 0.999 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.999 Unknown: traceable author statement GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.999 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus MLL1 complex (GO:0071339) 0.999 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed , PubMed 

O75461

Interaction Score
1

Q9ULU4

(UniProtKB/Swiss-Prot/P) Details

Protein kinase C-binding protein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Human Proteinpedia PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Dendritic shaft (GO:0043198) 0.51 Unknown: inferred from electronic annotation GO PubMed 
Membrane Dendritic spine (GO:0043197) 0.51 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75461

Interaction Score
1

Q9UJW3

(UniProtKB/Swiss-Prot/P) Details

DNA (cytosine-5)-methyltransferase 3-like

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.3 Unknown: HDA GO PubMed 
Nucleus Nucleus (GO:0005634) 0.999 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.999 Unknown: non-traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 0.999 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 0.999 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nuclear speck (GO:0016607) 0.999 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus ESC/E(Z) complex (GO:0035098) 0.999 Predicted: inferred from sequence or structural similarity GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.999

Q5VZL5

(UniProtKB/Swiss-Prot/P) Details

Zinc finger MYM-type protein 4

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.94 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Cytosol (GO:0005829) 0.94 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.998 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.998 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 0.998 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.998 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.998 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.999

Q8N668

(UniProtKB/Swiss-Prot/P) Details

COMM domain-containing protein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cul2-RING ubiquitin ligase complex (GO:0031462) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.998 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.998 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.998 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.998 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Recycling endosome (GO:0055037) 0.972 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Early endosome (GO:0005769) 0.972 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endosome membrane (GO:0010008) 0.972 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed , PubMed 

O75461

Interaction Score
0.999

Q9BYE7

(UniProtKB/Swiss-Prot/P) Details

Polycomb group RING finger protein 6

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.998 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.998 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.998 Unknown: traceable author statement GO PubMed 
Nucleus PcG protein complex (GO:0031519) 0.998 Experimental: inferred from direct assay GO PubMed 
Nucleus PRC1 complex (GO:0035102) 0.998 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

HPRD, BioGRID, IntAct

Interaction Source Publication:

PubMed , PubMed 

O75461

Interaction Score
0.996

Q9NX08

(UniProtKB/Swiss-Prot/P) Details

COMM domain-containing protein 8

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.988 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytosol (GO:0005829) 0.988 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.988 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.988 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.988 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.988 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed , PubMed 

O75461

Interaction Score
0.996

P10398

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein kinase A-Raf

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
N/A Cellular component (GO:0005575) 0.3 Unknown: no biological data available GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.91 Predicted: inferred from biological aspect of ancestor GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus Nucleus (GO:0005634) 0.988 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.988 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Fibrillar center (GO:0001650) 0.988 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.994

Q96II5

(UniProtKB/TrEmbl/P) Details

ARAF protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.988 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.988 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Fibrillar center (GO:0001650) 0.988 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.988

P05067

(UniProtKB/Swiss-Prot/P) Details

Amyloid-beta A4 protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 1 Experimental: experimental eSLDB PubMed 
Membrane Cell surface (GO:0009986) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Coated pit (GO:0005905) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Apical part of cell (GO:0045177) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Unknown: traceable author statement GO PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.96 Experimental: experimental eSLDB PubMed 
Nucleus Nuclear envelope lumen (GO:0005641) 0.96 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 1 Experimental: experimental eSLDB PubMed 
Secretory-pathway Rough endoplasmic reticulum (GO:0005791) 1 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Smooth endoplasmic reticulum (GO:0005790) 1 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Endoplasmic reticulum lumen (GO:0005788) 1 Unknown: traceable author statement GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 1 Experimental: experimental eSLDB PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Golgi lumen (GO:0005796) 1 Unknown: traceable author statement GO PubMed 
Secretory-pathway Trans-Golgi network membrane (GO:0032588) 1 Unknown: traceable author statement GO PubMed 
Secretory-pathway Endosome (GO:0005768) 1 Experimental: experimental eSLDB PubMed 
Secretory-pathway Endosome (GO:0005768) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endosome lumen (GO:0031904) 1 Unknown: traceable author statement GO PubMed 
Cytosol Lysosome (GO:0005764) 1 Experimental: experimental eSLDB PubMed 
Secretory-pathway Platelet alpha granule lumen (GO:0031093) 1 Unknown: traceable author statement GO PubMed 
Secretory-pathway ER to Golgi transport vesicle (GO:0030134) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Spindle midzone (GO:0051233) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Astrocyte projection (GO:0097449) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Dendritic shaft (GO:0043198) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Dendritic spine (GO:0043197) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Axon (GO:0030424) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Main axon (GO:0044304) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Ciliary rootlet (GO:0035253) 1 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.98 Experimental: experimental eSLDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.98 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.98 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular space (GO:0005615) 0.98 Unknown: HDA GO PubMed 
Membrane Membrane (GO:0016020) 1 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Membrane raft (GO:0045121) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: pTarget method LOCATE PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane Integral to plasma membrane (GO:0005887) 1 Unknown: traceable author statement GO PubMed 
Membrane Receptor complex (GO:0043235) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Vesicle (GO:0031982) 1 Experimental: experimental eSLDB PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 1 Unknown: HDA GO PubMed 
Membrane Cell-cell junction (GO:0005911) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Synapse (GO:0045202) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Neuromuscular junction (GO:0031594) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Presynaptic active zone (GO:0048786) 1 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.988

P04792

(UniProtKB/Swiss-Prot/P) Details

Heat shock protein beta-1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Unknown: traceable author statement GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Unknown: traceable author statement GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Proteasome complex (GO:0000502) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Nucleus Nucleus (GO:0005634) 0.96 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.96 Experimental: inferred from direct assay GO PubMed 
Cytosol Z disc (GO:0030018) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 1 Unknown: traceable author statement GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 1 Experimental: experimental Organelle PubMed 
Cytosol Spindle (GO:0005819) 1 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular space (GO:0005615) 0.86 Unknown: HDA GO PubMed 
Extracellular Extracellular matrix (GO:0031012) 0.86 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.98 Experimental: experimental MatrixDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.98 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.98 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 1 Unknown: HDA GO PubMed 
Membrane Focal adhesion (GO:0005925) 0.98 Unknown: HDA GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.988

P31949

(UniProtKB/Swiss-Prot/P) Details

Protein S100-A11

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.987 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.987 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.987 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.96 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.96 Experimental: experimental Organelle PubMed 
Secretory-pathway Secretory granule lumen (GO:0034774) 0.3 Unknown: traceable author statement GO PubMed 
Membrane Ruffle (GO:0001726) 0.972 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.51 Unknown: HDA GO PubMed 
Extracellular Extracellular space (GO:0005615) 0.51 Unknown: HDA GO PubMed 
Membrane Membrane (GO:0016020) 0.972 Experimental: experimental MatrixDB PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.987 Unknown: HDA GO PubMed 
Membrane Cell-cell adherens junction (GO:0005913) 0.972 Unknown: HDA GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.987

Q9H0A8

(UniProtKB/Swiss-Prot/P) Details

COMM domain-containing protein 4

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.988 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.988 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.988 Experimental: experimental Human Proteinpedia PubMed 
Nucleus Nucleus (GO:0005634) 0.958 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.958 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 0.958 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Plasma membrane (GO:0005886) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed , PubMed 

O75461

Interaction Score
0.982

P07948

(UniProtKB/Swiss-Prot/P) Details

Tyrosine-protein kinase Lyn

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Unknown: traceable author statement GO PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Mitochondrion Mitochondrial intermembrane space (GO:0005758) 0.51 Unknown: inferred from electronic annotation GO PubMed 
Mitochondrion Mitochondrial crista (GO:0030061) 0.51 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Predicted: inferred from sequence or structural similarity GO PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Experimental: experimental Human Proteinpedia PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.96 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Mast cell granule (GO:0042629) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Postsynaptic density (GO:0014069) 1 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane raft (GO:0045121) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Extrinsic to internal side of plasma membrane (GO:0031234) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Alpha2-beta1 integrin complex (GO:0034666) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 1 Unknown: HDA GO PubMed 
Membrane Cell-cell adherens junction (GO:0005913) 1 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.982

Q92569

(UniProtKB/Swiss-Prot/P) Details

Phosphatidylinositol 3-kinase regulatory subunit gamma

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.999 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.999 Unknown: traceable author statement GO PubMed 
Cytosol Phosphatidylinositol 3-kinase complex (GO:0005942) 0.999 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.999 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.94 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.973

Q5BJG6

(UniProtKB/TrEmbl/P) Details

ZMYND11 protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.973 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.973 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 0.973 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.973

Q8TAX8

(UniProtKB/TrEmbl/P) Details

MYC associated factor X

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.973 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.973 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 0.973 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.969

Q9UBT1

(UniProtKB/TrEmbl/P) Details

Estrogen receptor

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Predicted: pTarget method LOCATE PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.968

Q9Y242

(UniProtKB/Swiss-Prot/P) Details

Transcription factor 19

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.937 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.937 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 0.937 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.96

B7Z2J6

(UniProtKB/TrEmbl/P) Details

Zinc finger MYND domain-containing protein 11

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.96 Experimental: experimental eSLDB PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.96

J3QKD2

(UniProtKB/TrEmbl/P) Details

Zinc finger MYND domain-containing protein 11

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.96 Experimental: experimental eSLDB PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.95

Q7Z4G1

(UniProtKB/Swiss-Prot/P) Details

COMM domain-containing protein 6

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.937 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.937 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.937 Predicted: pTarget method LOCATE PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed , PubMed 

O75461

Interaction Score
0.94

Q6IT96

(UniProtKB/TrEmbl/P) Details

Histone deacetylase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.94 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Predicted: pTarget method LOCATE PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.94

P31151

(UniProtKB/Swiss-Prot/P) Details

Protein S100-A7

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.999 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.999 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.8 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.86 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Azurophil granule lumen (GO:0035578) 0.86 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.992 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular space (GO:0005615) 0.992 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular matrix (GO:0031012) 0.992 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.86 Experimental: experimental MatrixDB PubMed 
Membrane Focal adhesion (GO:0005925) 0.86 Unknown: non-traceable author statement GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.937

Q8WVV4

(UniProtKB/Swiss-Prot/P) Details

Protein POF1B

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.982 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.982 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Actin filament (GO:0005884) 0.982 Experimental: inferred from direct assay GO PubMed 
Membrane Adherens junction (GO:0005912) 0.972 Experimental: inferred from direct assay GO PubMed 
Membrane Desmosome (GO:0030057) 0.972 Unknown: inferred from electronic annotation GO PubMed 
Membrane Tight junction (GO:0005923) 0.972 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.912

E5RFV9

(UniProtKB/TrEmbl/P) Details

Caspase recruitment domain-containing protein 8

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.912

G3V302

(UniProtKB/TrEmbl/P) Details

Protein max

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.912

H0Y4W6

(UniProtKB/TrEmbl/P) Details

Estrogen receptor

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.91

Q5UGI2

(UniProtKB/TrEmbl/P) Details

Zinc finger MYND domain containing 11 transcript variant 3

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.91 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.91 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.897

Q9NWX5

(UniProtKB/Swiss-Prot/P) Details

Ankyrin repeat and SOCS box protein 6

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.937 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.937 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.937 Unknown: traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.847

Q59FG6

(UniProtKB/TrEmbl/P) Details

Myeloid/lymphoid or mixed-lineage leukemia 2 variant

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: pTarget method LOCATE PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.847

Q6PIA1

(UniProtKB/TrEmbl/P) Details

MLL2 protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: pTarget method LOCATE PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.847

Q68CY7

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein DKFZp686P05226

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.847

Q7Z3W2

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein DKFZp686F1293

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.847

Q8N381

(UniProtKB/TrEmbl/P) Details

Phosphoinositide-3-kinase, regulatory subunit 3

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.8

A0A0A0MSY9

(UniProtKB/TrEmbl/P) Details

Histone-lysine N-methyltransferase EZH1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleoplasm (GO:0005654) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.8

A0A087WVZ6

(UniProtKB/TrEmbl/P) Details

Protein kinase C-binding protein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleoplasm (GO:0005654) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.8

E9PJK2

(UniProtKB/TrEmbl/P) Details

Polycomb protein EED

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleoplasm (GO:0005654) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.8

G3V212

(UniProtKB/TrEmbl/P) Details

YY1 associated factor 2, isoform CRA_b

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleoplasm (GO:0005654) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.8

A0A0B4J287

(UniProtKB/TrEmbl/P) Details

COMM domain-containing protein 4

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Plasma membrane (GO:0005886) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.8

H3BQF2

(UniProtKB/TrEmbl/P) Details

COMM domain-containing protein 4

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Plasma membrane (GO:0005886) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.79

P09211

(UniProtKB/Swiss-Prot/P) Details

Glutathione S-transferase P

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol TRAF2-GSTP1 complex (GO:0097057) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Intracellular (GO:0005622) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Unknown: traceable author statement GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.988 Predicted: SVM decision tree eSLDB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.988 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.988 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Secretory granule lumen (GO:0034774) 0.3 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.51 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular space (GO:0005615) 0.51 Unknown: HDA GO PubMed 
Membrane Membrane (GO:0016020) 0.86 Experimental: experimental MatrixDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Vesicle (GO:0031982) 1 Unknown: HDA GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 1 Unknown: HDA GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.789

Q9BQE3

(UniProtKB/Swiss-Prot/P) Details

Tubulin alpha-1C chain

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.999 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.3 Unknown: HDA GO PubMed 
Cytosol Microtubule cytoskeleton (GO:0015630) 0.999 Experimental: inferred from direct assay GO PubMed 
Cytosol Microtubule cytoskeleton (GO:0015630) 0.999 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Microtubule (GO:0005874) 0.999 Unknown: traceable author statement GO PubMed 
Cytosol Vesicle (GO:0031982) 0.999 Unknown: HDA GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.775

P05089

(UniProtKB/Swiss-Prot/P) Details

Arginase-1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Neuronal cell body (GO:0043025) 0.969 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.969 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.969 Unknown: traceable author statement GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.969 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.969 Unknown: traceable author statement GO PubMed 
Mitochondrion Mitochondrial outer membrane (GO:0005741) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.3 Unknown: HDA GO PubMed 
Secretory-pathway Azurophil granule lumen (GO:0035578) 0.3 Unknown: traceable author statement GO PubMed 
Membrane Neuron projection (GO:0043005) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.86 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular space (GO:0005615) 0.86 Experimental: inferred from direct assay GO PubMed 
Membrane Membrane (GO:0016020) 0.86 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.718

P47929

(UniProtKB/Swiss-Prot/P) Details

Galectin-7

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.853 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.853 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular space (GO:0005615) 0.3 Unknown: traceable author statement GO PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.853 Unknown: HDA GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.7

A4D177

(UniProtKB/TrEmbl/P) Details

Chromobox homolog 3 (HP1 gamma homolog, Drosophila), isoform CRA_a

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.7

Q2HXV5

(UniProtKB/TrEmbl/P) Details

RACK7 isoform g

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.7

Q569J9

(UniProtKB/TrEmbl/P) Details

ZMYND8 protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.7

P22528

(UniProtKB/Swiss-Prot/P) Details

Cornifin-B

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: pTarget method LOCATE PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Unknown: traceable author statement GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 1 Experimental: experimental Organelle PubMed 
Cytosol Cornified envelope (GO:0001533) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.7

P22531

(UniProtKB/Swiss-Prot/P) Details

Small proline-rich protein 2E

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Unknown: traceable author statement GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 1 Experimental: experimental Organelle PubMed 
Cytosol Cornified envelope (GO:0001533) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.694

Q08188

(UniProtKB/Swiss-Prot/P) Details

Protein-glutamine gamma-glutamyltransferase E

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.992 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.992 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 0.992 Experimental: experimental Organelle PubMed 
Extracellular Extracellular region (GO:0005576) 0.7 Predicted: pTarget method LOCATE PubMed 
Membrane Membrane (GO:0016020) 0.992 Experimental: experimental MatrixDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.992 Experimental: experimental Organelle PubMed 
Membrane Extrinsic to internal side of plasma membrane (GO:0031234) 0.992 Experimental: inferred from direct assay GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.992 Unknown: HDA GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.691

P05090

(UniProtKB/Swiss-Prot/P) Details

Apolipoprotein D

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.94 Experimental: experimental eSLDB PubMed 
Cytosol Neuronal cell body (GO:0043025) 0.987 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Cytosolic ribosome (GO:0022626) 0.987 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 0.987 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.94 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Dendrite (GO:0030425) 0.988 Predicted: inferred from sequence or structural similarity GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.853 Unknown: non-traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.853 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 0.853 Unknown: HDA GO PubMed 
Membrane Membrane (GO:0016020) 0.988 Experimental: experimental MatrixDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.988 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.987 Unknown: HDA GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.679

P62891

(UniProtKB/Swiss-Prot/P) Details

60S ribosomal protein L39

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.971 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Polysomal ribosome (GO:0042788) 0.971 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.971 Unknown: traceable author statement GO PubMed 
Cytosol Cytosolic large ribosomal subunit (GO:0022625) 0.971 Unknown: HDA GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: pTarget method LOCATE PubMed 
Extracellular Extracellular space (GO:0005615) 0.8 Experimental: inferred from direct assay GO PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.637

Q6NUK7

(UniProtKB/TrEmbl/P) Details

Tyrosine-protein kinase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Plasma membrane (GO:0005886) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.56

A0A0A0MRG2

(UniProtKB/TrEmbl/P) Details

Amyloid-beta A4 protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Integral to membrane (GO:0016021) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.56

E9PG40

(UniProtKB/TrEmbl/P) Details

Amyloid-beta A4 protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.56

P00367

(UniProtKB/Swiss-Prot/P) Details

Glutamate dehydrogenase 1, mitochondrial

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.8 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.999 Experimental: experimental eSLDB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.999 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.999 Predicted: pTarget method LOCATE PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.999 Predicted: PAML algorithm PA-GOSUB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.999 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Mitochondrion Mitochondrial matrix (GO:0005759) 0.999 Unknown: traceable author statement GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.357

P60409

(UniProtKB/Swiss-Prot/P) Details

Keratin-associated protein 10-7

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytosol (GO:0005829) 0.51 Unknown: traceable author statement GO PubMed 
Cytosol Keratin filament (GO:0045095) 0.51 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.7 Predicted: pTarget method LOCATE PubMed 

Interaction Source Database:

CCSB, BioGRID, IntAct

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.21

P01036

(UniProtKB/Swiss-Prot/P) Details

Cystatin-S

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.79 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 0.79 Unknown: HDA GO PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.3 Unknown: HDA GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.21

P02814

(UniProtKB/Swiss-Prot/P) Details

Submaxillary gland androgen-regulated protein 3B

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.8 Experimental: experimental eSLDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.79 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 0.79 Unknown: traceable author statement GO PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.3 Unknown: HDA GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0.21

P04745

(UniProtKB/Swiss-Prot/P) Details

Alpha-amylase 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.8 Experimental: experimental eSLDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.937 Predicted: pTarget method LOCATE PubMed 
Extracellular Extracellular region (GO:0005576) 0.937 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 0.937 Unknown: HDA GO PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.3 Unknown: HDA GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0

Q00765

(UniProtKB/Swiss-Prot/P) Details

Receptor expression-enhancing protein 5

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Endoplasmic reticulum tubular network (GO:0071782) 0.96 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.86 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.86 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

O75461

Interaction Score
0

P09228

(UniProtKB/Swiss-Prot/P) Details

Cystatin-SA

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.8 Experimental: experimental eSLDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.79 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 0.79 Unknown: HDA GO PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

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ComPPI is published in Nucleic Acids Research Database Issue 2015